Title: 4 Stars Hotels in Mediterranean Region, from CA $153 - Find Cheap Mediterranean Region Hotels With 4 Stars | Expedia.ca [Mediterranean Region Travel Guide](https://expedia.ca/Mediterranean-Region.dx844522342175883264)[Hotels in Mediterranean Region](https://expedia.ca/Mediterranean-Region-Hotels.d844522342175883264.Travel-Guide-Hotels)[Vacation Rentals in Mediterranean Region](https://expedia.ca/Mediterranean-Region-Vacation-Rentals.d844522342175883264.Travel-Guide-VacationRentals)[Flights to Mediterranean Region](https://expedia.ca/Cheap-Flights-To-Mediterranean-Region.d844522342175883264.Travel-Guide-Flights)[Mediterranean Region Car Rentals](https://expedia.ca/Car-Rentals-In-Mediterranean-Region.d844522342175883264.Car-Rental-Guide)[Mediterranean Region Vacation Packages](https://expedia.ca/Mediterranean-Region.d844522342175883264.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/9/abc24df6f2e3266327aa8b559e87e79a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 4 Stars Hotels in Mediterranean Region, from CA $153 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mediterranean Region 4 Star Hotels Tonight [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-10-24&endDate=2025-10-25&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-10-25&endDate=2025-10-26&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-10-31&endDate=2025-11-02&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mediterranean Region 4 Star Hotels ![Suite, 2 Bedrooms](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/ab2f831e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/a2a10c4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 19.80 per person)](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/d6482991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/ff31abe1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Barcelona Airport Hotel El Prat de Llobregat 8.6/10 Excellent (5018) "Would stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara CA $183 CA $206 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/Barcelona-Hotels-Barcelona-Airport-Hotel.h1439964.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/df3b5a06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/926d9120.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast buffet](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/w3000h1997x0y0-6151e0e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/97577ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Quirinale Rome City Centre 8.6/10 Excellent (1897) "Fantastic stay, centrally located with every amenity. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Desiree CA $221 CA $267 total includes taxes & fees Nov 18 - Nov 19 [](https://www.expedia.ca/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/530000/524600/524550/907de448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/530000/524600/524550/293d76dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food court](https://images.trvl-media.com/lodging/1000000/530000/524600/524550/f603c10a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/530000/524600/524550/cd478a3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Blu Hotel Lisbon City Center 8.2/10 Very good (2064) "We throughly enjoyed our family stay! " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jonathan CA $166 CA $189 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Lisbon-District-Hotels-Radisson-Blu-Hotel.h524550.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/50000/46600/46579/e98b4189.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/46600/46579/9205c7ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/50000/46600/46579/0e38920e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/1000000/50000/46600/46579/5c1e9a1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HF Fénix Lisboa Lisbon City Center 9.0/10 Wonderful (1003) "Great location, clean, excellent breakfast, staffs are so helpful and friendly especially Nelson. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Foroogh CA $132 CA $153 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Lisbon-District-Hotels-HF-Fenix-Lisboa.h46579.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/1000000/600000/598800/598707/bdf586a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Concierge desk](https://images.trvl-media.com/lodging/1000000/600000/598800/598707/63818f66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/600000/598800/598707/0ec66f53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/600000/598800/598707/6731a47e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Liabeny Madrid Centro 9.4/10 Exceptional (1465) "Goood hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bruny CA $260 CA $287 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Madrid-Hotels-Hotel-Liabeny.h598707.Hotel-Information) ![Suite Exterior (Aduana) | Living area](https://images.trvl-media.com/lodging/2000000/1180000/1170200/1170158/559c033d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1180000/1170200/1170158/f190b90c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite (Interior)](https://images.trvl-media.com/lodging/2000000/1180000/1170200/1170158/dd18821b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Penthouse, Hot Tub (Terrace)](https://images.trvl-media.com/lodging/2000000/1180000/1170200/1170158/8638c5ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Regina Madrid Centro 9.8/10 Exceptional (2176) "Really clean rooms, great staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christian CA $383 CA $422 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Madrid-Hotels-Hotel-Regina.h1170158.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/1000000/70000/68700/68689/81eaf4dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, Connecting Rooms (Balcony)](https://images.trvl-media.com/lodging/1000000/70000/68700/68689/9675b521.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/70000/68700/68689/316bb334.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/70000/68700/68689/d7553cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### INNSiDE by Melia Barcelona Apolo El Poble-sec 9.4/10 Exceptional (1428) "Great staff, location and clean hotel. Close to many famous tourist spots. Many great restaurants walking distance from hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pratik CA $258 CA $304 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Barcelona-Hotels-Hotel-Barcelona-Apolo.h68689.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/1500/1487/068d97a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Single Beds, Non Smoking (City View)](https://images.trvl-media.com/lodging/1000000/10000/1500/1487/98c7e2b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/1500/1487/544d6d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/1500/1487/d8ae337e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Moxy Barcelona Sants-Montjuïc 8.4/10 Very good (415) "Great place to stay." ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Elias Eduardo Solorzano de la CA $170 CA $207 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/Barcelona-Hotels-Moxy-Barcelona.h1487.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/24900/24814/27b61dc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/24900/24814/3e57499b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 28 per person)](https://images.trvl-media.com/lodging/1000000/30000/24900/24814/faf7bf86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/24900/24814/b955e0c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madrid Marriott Hotel Princesa Plaza Madrid Centro 8.8/10 Excellent (1393) "Had an amazing stay at this property. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mariz Stella CA $306 CA $336 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Madrid-Hotels-Hotel-Princesa-Plaza-Madrid.h24814.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/25700/25620/ee513b44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/25700/25620/05054966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/25700/25620/b244436f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 13.95 per person)](https://images.trvl-media.com/lodging/1000000/30000/25700/25620/73ea25a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Gran Versalles Chamberí 8.8/10 Excellent (1003) "I highly recommend this hotel. Nice rooms, clean and convenient. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rossmery CA $222 CA $244 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Madrid-Hotels-Hotel-Gran-Versalles.h25620.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/564200/564180/cf85cac6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/570000/564200/564180/b33d0995.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/570000/564200/564180/f7fcf37e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/570000/564200/564180/6222a531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Rome Airport Fiumicino 8.0/10 Very good (3184) "Excellent location Biggest compliment was the service & breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kesha CA $278 CA $325 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Rome-Hotels-Hilton-Rome-Airport.h564180.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1160000/1153200/1153145/94384cee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1153200/1153145/3983dc49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Roomy View | City view](https://images.trvl-media.com/lodging/2000000/1160000/1153200/1153145/917e3c89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; pizza](https://images.trvl-media.com/lodging/2000000/1160000/1153200/1153145/191f7bd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Hoxton Poblenou Sant Martí 9.0/10 Wonderful (535) "Fantastic location for the Design Week" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $193 CA $232 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Barcelona-Hotels-The-Hoxton-Poblenou.h1153145.Hotel-Information) ![Rock Star Suite](https://images.trvl-media.com/lodging/67000000/66910000/66907000/66906927/f79da699.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/67000000/66910000/66907000/66906927/f98c3931.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/67000000/66910000/66907000/66906927/d4593347.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rock Star Suite | Terrace/patio](https://images.trvl-media.com/lodging/67000000/66910000/66907000/66906927/b5a76fd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hard Rock Hotel Madrid Arganzuela 9.4/10 Exceptional (2312) "Great place to stay and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Americo CA $295 CA $325 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Madrid-Hotels-Hard-Rock-Hotel-Madrid.h66906927.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1590000/1587200/1587154/09c9808f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1590000/1587200/1587154/6e9d9bc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1590000/1587200/1587154/32debd2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1590000/1587200/1587154/823530ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Rome Airport Fiumicino 8.2/10 Very good (3384) "Amazing place to stay ! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ileana CA $236 CA $280 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/Rome-Hotels-Hilton-Garden-Inn-Rome-Airport.h1587154.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/1000000/10000/6400/6371/849fb031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/6400/6371/071683cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/6400/6371/67057582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/6400/6371/84ad3fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Baglioni Historic Centre of Florence 9.0/10 Wonderful (1040) "Fantastic stay!! A wonderful hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan CA $227 CA $273 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Florence-Hotels-Grand-Hotel-Baglioni.h6371.Hotel-Information) ![Outdoor pool, a heated pool, open 9:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/50000/45400/45395/0fd5e63f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/50000/45400/45395/f04a29f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar, pool views, open daily](https://images.trvl-media.com/lodging/1000000/50000/45400/45395/90bdf6af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/50000/45400/45395/5ca2d5e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Stanley Athens City Centre 8.8/10 Excellent (2043) "Excellent Hotel!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $135 CA $170 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Athens-Hotels-The-Stanley.h45395.Hotel-Information) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/95000000/94710000/94706900/94706900/2bd1dac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/95000000/94710000/94706900/94706900/48347036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/95000000/94710000/94706900/94706900/09cc2b0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/95000000/94710000/94706900/94706900/60762c8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### citizenM Rome Isola Tiberina Rome City Centre 9.6/10 Exceptional (719) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sabrina CA $272 CA $323 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Rome-Hotels-CitizenM-Rome-Isola-Tiberina.h94706900.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/42fcab3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar, lobby lounge](https://images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/93c5eda6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar, lobby lounge](https://images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/b9437e87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 7:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/61a4486f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza España Madrid Centro 9.4/10 Exceptional (4411) "Great hotel and service! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cynthia nory CA $294 CA $324 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Madrid-Hotels-Hotel-Riu-Plaza-Espana.h29345493.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/1000000/60000/54200/54154/104d793e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/60000/54200/54154/cd2c7794.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/60000/54200/54154/0ab142af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Suite | Living area](https://images.trvl-media.com/lodging/1000000/60000/54200/54154/050b307b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Delle Nazioni Rome City Centre 9.0/10 Wonderful (1020) "Friendly staff, clean and great breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Claudia CA $235 CA $283 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Rome-Hotels-Hotel-Delle-Nazioni.h54154.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/8000000/7370000/7369700/7369640/b05af088.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7370000/7369700/7369640/2ff4db25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/8000000/7370000/7369700/7369640/2a0c4c65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room](https://images.trvl-media.com/lodging/8000000/7370000/7369700/7369640/2c646af5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Meliá Lisboa Aeroporto Lisbon 9.4/10 Exceptional (2853) "Great room, lovely airport hotel, good breakfast and walkable in a couple of minutes from the terminal. Would stay again!" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Laurie CA $262 CA $291 total includes taxes & fees Nov 15 - Nov 16 [](https://www.expedia.ca/Lisbon-District-Hotels-Melia-Lisboa-Aeroporto.h7369640.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Mediterranean-Region-Hotels.s40-0-d844522342175883264.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Mediterranean-Region-Hotels.s40-0-d844522342175883264.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Mediterranean Region. ![InterContinental Barcelona by IHG](https://images.trvl-media.com/lodging/1000000/30000/28300/28279/3e96c0d9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### InterContinental Barcelona by IHG Avenida Ruis I Taulet 1-3, Barcelona CA $318 CA $376 total Nov 16 - Nov 17 includes taxes & fees 9.2/10 Wonderful! (999 reviews) [](https://expedia.ca/Barcelona-Hotels-InterContinental-Barcelona.h28279.Hotel-Information) ![Lamaro Hotel](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/a07cf64a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Lamaro Hotel Avenida Catedral, 7, Barcelona CA $361 CA $424 total Oct 26 - Oct 27 includes taxes & fees 9.4/10 Exceptional! (1,811 reviews) [](https://expedia.ca/Barcelona-Hotels-Hotel-Colon-Barcelona.h3388.Hotel-Information) ![Grand Hyatt Athens](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/dbfe795f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Grand Hyatt Athens 115, Syngrou Avenue, Athens, Attica CA $143 CA $169 total Nov 11 - Nov 12 includes taxes & fees 8.6/10 Excellent! (894 reviews) [](https://expedia.ca/Athens-Hotels-Grand-Hyatt-Athens.h21031.Hotel-Information) Still don't see what you're looking for? [See all properties in Mediterranean Region.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=25%2F10%2F2025&endDate=26%2F10%2F2025®ionId=844522342175883264&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=25%2F10%2F2025&endDate=26%2F10%2F2025®ionId=844522342175883264&star=40&star=40&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=25%2F10%2F2025&endDate=26%2F10%2F2025®ionId=844522342175883264&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=25%2F10%2F2025&endDate=26%2F10%2F2025®ionId=844522342175883264&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=25%2F10%2F2025&endDate=26%2F10%2F2025®ionId=844522342175883264&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=25%2F10%2F2025&endDate=26%2F10%2F2025®ionId=844522342175883264&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Mediterranean Region During your stay in Mediterranean Region, you can discover things to see and do in the local area. [See all hotels in Mediterranean Region](https://www.expedia.ca/Hotel-Search?startDate=2025-11-07&endDate=2025-11-08&adults=2®ionId=844522342175883264) ![Basilica de Santa Maria del Mar showing a church or cathedral and heritage architecture](https://images.trvl-media.com/place/6066991/c3c69d6e-c998-4f36-ad18-3e65173208c0.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Mediterranean Region Hotel Reviews ![Barcelona Airport Hotel](//images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/ab2f831e_y.jpg) ### Barcelona Airport Hotel 10/10 Excellent "Excellent hotel." [](https://expedia.ca/Barcelona-Hotels-Barcelona-Airport-Hotel.h1439964.Hotel-Information) ![Hotel Liabeny](//images.trvl-media.com/lodging/1000000/600000/598800/598707/bdf586a9_y.jpg) ### Hotel Liabeny 10/10 Excellent "The only suggestion for the breakfast menu would be to somehow keep the eggs hotter. They were appealing but not arm enough for me. " [](https://expedia.ca/Madrid-Hotels-Hotel-Liabeny.h598707.Hotel-Information) ![Locke de Santa Joana](//images.trvl-media.com/lodging/103000000/102360000/102360000/102359957/2f274b13_y.jpg) ### Locke de Santa Joana 10/10 Excellent "Amazing property!! " [](https://expedia.ca/Lisbon-District-Hotels-Locke-De-Santa-Joana.h102359957.Hotel-Information) ![The Hoxton Poblenou](//images.trvl-media.com/lodging/2000000/1160000/1153200/1153145/94384cee_y.jpg) ### The Hoxton Poblenou 10/10 Excellent "Thank you Hoxton!" [](https://expedia.ca/Barcelona-Hotels-The-Hoxton-Poblenou.h1153145.Hotel-Information) ![Hotel Riu Plaza España](//images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/42fcab3f_y.jpg) ### Hotel Riu Plaza España 10/10 Excellent "Property in excellent conditions!! Great service, beautiful rooftop! " [](https://expedia.ca/Madrid-Hotels-Hotel-Riu-Plaza-Espana.h29345493.Hotel-Information) ![Hotel Acta Moa- New Opening](//images.trvl-media.com/lodging/118000000/117140000/117137400/117137301/1fd8b13a_y.jpg) ### Hotel Acta Moa- New Opening 10/10 Excellent "The Service was excellent. Carlota and Mark were very helpful. " [](https://expedia.ca/Lisbon-District-Hotels-Acta-Moa.h117137301.Hotel-Information) ![Hotel Quirinale](//images.trvl-media.com/lodging/1000000/10000/1100/1058/df3b5a06_y.jpg) ### Hotel Quirinale 10/10 Excellent "Their place is very clean and staffs are so helpful! It’s a walking distance from many main attractions such as the colosseum as well as the Trevi fountain! More importantly, it is a walking distance from the termini! " [](https://expedia.ca/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) ![citizenM Rome Isola Tiberina](//images.trvl-media.com/lodging/95000000/94710000/94706900/94706900/2bd1dac3_y.jpg) ### citizenM Rome Isola Tiberina 10/10 Excellent "excellent" [](https://expedia.ca/Rome-Hotels-CitizenM-Rome-Isola-Tiberina.h94706900.Hotel-Information) ![Bettoja Hotel Mediterraneo](//images.trvl-media.com/lodging/1000000/10000/8800/8711/05f1eca2_y.jpg) ### Bettoja Hotel Mediterraneo 10/10 Excellent "Clean, big single room with 2 closet and space for the luggages. You can see the property when you get out from the Roma Termini" [](https://expedia.ca/Rome-Hotels-Bettoja-Hotel-Mediterraneo.h8711.Hotel-Information) ## Find out more about Mediterranean Region If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Mediterranean Region are calling your name. Known for providing first-rate service in amazing locations, each of the Mediterranean Region 4 Stars hotels lets discerning travelers bask in an unforgettable experience. Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day. It’s all waiting for you at the top four star hotels in Mediterranean Region. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Mediterranean Region, , neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Mediterranean Region hotels with 4 Stars provide everything you need to unwind in style.