Title: 4 Stars Hotels in Mediterranean Region, from CA $121 - Find Cheap Mediterranean Region Hotels With 4 Stars | Expedia.ca [Mediterranean Region Travel Guide](https://expedia.ca/Mediterranean-Region.dx844522342175883264)[Hotels in Mediterranean Region](https://expedia.ca/Mediterranean-Region-Hotels.d844522342175883264.Travel-Guide-Hotels)[Vacation Rentals in Mediterranean Region](https://expedia.ca/Mediterranean-Region-Vacation-Rentals.d844522342175883264.Travel-Guide-VacationRentals)[Flights to Mediterranean Region](https://expedia.ca/Cheap-Flights-To-Mediterranean-Region.d844522342175883264.Travel-Guide-Flights)[Mediterranean Region Car Rentals](https://expedia.ca/Car-Rentals-In-Mediterranean-Region.d844522342175883264.Car-Rental-Guide)[Mediterranean Region Vacation Packages](https://expedia.ca/Mediterranean-Region.d844522342175883264.Destination-Travel-Guides) ![Mazarrón, Spain](https://images.trvl-media.com/place/553248633936349954/597750c4-7c4e-4a36-b33c-904705e647c4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 4 Stars Hotels in Mediterranean Region, from CA $121 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mediterranean Region 4 Star Hotels Tonight [Dec 11 - Dec 12](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-12-11&endDate=2025-12-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 12 - Dec 13](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-12-12&endDate=2025-12-13&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-12-12&endDate=2025-12-14&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-12-19&endDate=2025-12-21&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mediterranean Region 4-star hotels ![Suite, 2 Bedrooms](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/ab2f831e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 19.80 per person)](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/d6482991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/361fc5bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/a2a10c4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Barcelona Airport Hotel [](https://www.expedia.ca/Barcelona-Hotels-Barcelona-Airport-Hotel.h1439964.Hotel-Information) El Prat de Llobregat 8.6/10 Excellent (5143) "Nice rooms, comfortable beds, great breakfast. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) NIDIA CA $187 CA $210 total includes taxes & fees Dec 12 - Dec 13 [](https://www.expedia.ca/Barcelona-Hotels-Barcelona-Airport-Hotel.h1439964.Hotel-Information) ![Daily buffet breakfast (EUR 13 per person)](https://images.trvl-media.com/lodging/1000000/10000/8800/8711/05f1eca2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/8800/8711/769a8858.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Premium Room](https://images.trvl-media.com/lodging/1000000/10000/8800/8711/137b4400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/10000/8800/8711/b3b84d3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bettoja Hotel Mediterraneo [](https://www.expedia.ca/Rome-Hotels-Bettoja-Hotel-Mediterraneo.h8711.Hotel-Information) Rome City Centre 8.6/10 Excellent (1001) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sabah CA $269 CA $321 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Rome-Hotels-Bettoja-Hotel-Mediterraneo.h8711.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1000/915/2f47a159.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers, lifeguards on site](https://images.trvl-media.com/lodging/1000000/10000/1000/915/59eabdfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/1000/915/d24a46e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/1000/915/085fa0c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Emperador [](https://www.expedia.ca/Madrid-Hotels-Hotel-Emperador.h915.Hotel-Information) Madrid Centro 9.2/10 Wonderful (1888) "The rooms and the hotel stood out in cleanliness also the staff was very friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alan Martin CA $203 CA $223 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Madrid-Hotels-Hotel-Emperador.h915.Hotel-Information) ![Suite Exterior (Aduana)](https://images.trvl-media.com/lodging/2000000/1180000/1170200/1170158/e8709f28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite (Interior)](https://images.trvl-media.com/lodging/2000000/1180000/1170200/1170158/dd18821b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Penthouse, Hot Tub (Terrace)](https://images.trvl-media.com/lodging/2000000/1180000/1170200/1170158/8638c5ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 25 per person)](https://images.trvl-media.com/lodging/2000000/1180000/1170200/1170158/99d6c383.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Regina [](https://www.expedia.ca/Madrid-Hotels-Hotel-Regina.h1170158.Hotel-Information) Madrid Centro 9.8/10 Exceptional (2210) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marisol CA $293 CA $322 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Madrid-Hotels-Hotel-Regina.h1170158.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/6600/6548/9e2b5c71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/1000000/10000/6600/6548/51590ab2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/10000/6600/6548/8dba7d16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/6600/6548/fa1f2ab3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Napoleon Hotel [](https://www.expedia.ca/Rome-Hotels-Napoleon-Hotel.h6548.Hotel-Information) Rome City Centre 8.4/10 Very good (1006) "Perfect location and great breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcia CA $153 CA $192 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Rome-Hotels-Napoleon-Hotel.h6548.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/1500/1487/068d97a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Single Beds, City View](https://images.trvl-media.com/lodging/1000000/10000/1500/1487/98c7e2b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1500/1487/e2492ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/1500/1487/d8ae337e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Moxy Barcelona [](https://www.expedia.ca/Barcelona-Hotels-Moxy-Barcelona.h1487.Hotel-Information) Sants-Montjuïc 8.4/10 Very good (451) "The staff was amazing! Really all of them. The cool vibe of the public space puts one at ease. Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rhonda CA $157 CA $193 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Barcelona-Hotels-Moxy-Barcelona.h1487.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/df3b5a06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/97577ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/d23d4f1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast buffet](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/w3000h1997x0y0-6151e0e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Quirinale [](https://www.expedia.ca/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) Rome City Centre 8.6/10 Excellent (1912) "Very nice stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monique CA $193 CA $237 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/1000000/600000/598800/598707/bdf586a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/600000/598800/598707/0ec66f53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Concierge desk](https://images.trvl-media.com/lodging/1000000/600000/598800/598707/63818f66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/600000/598800/598707/6731a47e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Liabeny [](https://www.expedia.ca/Madrid-Hotels-Hotel-Liabeny.h598707.Hotel-Information) Madrid Centro 9.4/10 Exceptional (1479) "Clean, convenient location, best breakfast" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) QING CA $235 CA $259 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Madrid-Hotels-Hotel-Liabeny.h598707.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/42fcab3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar, lobby lounge](https://images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/b9437e87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/db10d65a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 7:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/61a4486f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza España [](https://www.expedia.ca/Madrid-Hotels-Hotel-Riu-Plaza-Espana.h29345493.Hotel-Information) Madrid Centro 9.4/10 Exceptional (4515) "Great hotel, friendly staff, close to everything , amazing food and wonderful breakfast! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dora C CA $221 CA $243 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Madrid-Hotels-Hotel-Riu-Plaza-Espana.h29345493.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/6500/6444/df3566a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/6500/6444/6a11402b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/6500/6444/2febd567.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/6500/6444/8700b7b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Chamartin The One [](https://www.expedia.ca/Madrid-Hotels-Hotel-Chamartin-The-One.h6444.Hotel-Information) Chamartín 8.6/10 Excellent (1007) "Hotel is just Great . Outside the train stations looks horrible and dirty but once you go inside " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jhon CA $155 CA $171 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Madrid-Hotels-Hotel-Chamartin-The-One.h6444.Hotel-Information) ![Outdoor pool, a heated pool, open 9:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/50000/45400/45395/0fd5e63f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar, pool views, open daily](https://images.trvl-media.com/lodging/1000000/50000/45400/45395/7f93b28e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/50000/45400/45395/f04a29f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar, pool views, open daily](https://images.trvl-media.com/lodging/1000000/50000/45400/45395/90bdf6af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Stanley [](https://www.expedia.ca/Athens-Hotels-The-Stanley.h45395.Hotel-Information) Athens City Centre 8.8/10 Excellent (2078) "Great service amazing people close to Metro and a lot of good places" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Ramzi CA $126 CA $148 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Athens-Hotels-The-Stanley.h45395.Hotel-Information) ![Junior Suite | View from room](https://images.trvl-media.com/lodging/1000000/900000/891700/891685/41686160.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/891700/891685/99e99430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double or Twin Room, 1 Double Bed](https://images.trvl-media.com/lodging/1000000/900000/891700/891685/dab7b765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/900000/891700/891685/4723cd54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Isola Sacra Rome Airport [](https://www.expedia.ca/Rome-Hotels-Hotel-Isola-Sacra-Rome-Airport.h891685.Hotel-Information) Isola Sacra 9.0/10 Wonderful (1391) "Really lovely hotel with great beds and a wonderful breakfast " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Chantelle CA $98 CA $121 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Rome-Hotels-Hotel-Isola-Sacra-Rome-Airport.h891685.Hotel-Information) ![Rock Star Suite](https://images.trvl-media.com/lodging/67000000/66910000/66907000/66906927/f79da699.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/67000000/66910000/66907000/66906927/d4593347.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 24 per person)](https://images.trvl-media.com/lodging/67000000/66910000/66907000/66906927/d093c2d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/67000000/66910000/66907000/66906927/f98c3931.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hard Rock Hotel Madrid [](https://www.expedia.ca/Madrid-Hotels-Hard-Rock-Hotel-Madrid.h66906927.Hotel-Information) Arganzuela 9.4/10 Exceptional (2402) "La habitación súper limpia, el check in la gente muy amable, toda la estancia fue genial." ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Ana CA $220 CA $242 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Madrid-Hotels-Hard-Rock-Hotel-Madrid.h66906927.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/1000000/50000/46900/46853/c0b65756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/46900/46853/cf795ec3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/50000/46900/46853/97a49cca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 23 per person)](https://images.trvl-media.com/lodging/1000000/50000/46900/46853/ee5822b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Barceló Sants [](https://www.expedia.ca/Barcelona-Hotels-Barcelo-Sants.h46853.Hotel-Information) Sants-Montjuïc 9.0/10 Wonderful (1448) "Great location,friendly staff and comfy beds." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rafael CA $148 CA $183 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Barcelona-Hotels-Barcelo-Sants.h46853.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/1000000/60000/54200/54154/104d793e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/60000/54200/54154/0ab142af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Suite | Living area](https://images.trvl-media.com/lodging/1000000/60000/54200/54154/050b307b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/54200/54154/97f36694.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Delle Nazioni [](https://www.expedia.ca/Rome-Hotels-Hotel-Delle-Nazioni.h54154.Hotel-Information) Rome City Centre 9.0/10 Wonderful (1005) "Clean room, good service and excellent breakfast" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Bassam CA $261 CA $311 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Rome-Hotels-Hotel-Delle-Nazioni.h54154.Hotel-Information) ![Breakfast, lunch, dinner served; Mediterranean cuisine ](https://images.trvl-media.com/lodging/1000000/60000/54500/54490/35c80e1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/60000/54500/54490/aade7ae7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/1000000/60000/54500/54490/6c48d50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/54500/54490/454f8a85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grupotel Mayorazgo [](https://www.expedia.ca/Madrid-Hotels-Hotel-Mayorazgo.h54490.Hotel-Information) Madrid Centro 8.4/10 Very good (796) "Nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pamela CA $237 CA $261 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Madrid-Hotels-Hotel-Mayorazgo.h54490.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1160000/1153200/1153145/94384cee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1153200/1153145/3983dc49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1160000/1153200/1153145/c119b91f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Roomy View | City view](https://images.trvl-media.com/lodging/2000000/1160000/1153200/1153145/917e3c89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Hoxton Poblenou [](https://www.expedia.ca/Barcelona-Hotels-The-Hoxton-Poblenou.h1153145.Hotel-Information) Sant Martí 9.0/10 Wonderful (572) "A very charming hotel in a great part of Barcelon." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cassandra CA $222 CA $265 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/Barcelona-Hotels-The-Hoxton-Poblenou.h1153145.Hotel-Information) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/50000/47000/46910/41d02d4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/47000/46910/02e5dc34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/50000/47000/46910/e628cbb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/50000/47000/46910/7c07342b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### voco Madrid Retiro by IHG [](https://www.expedia.ca/Madrid-Hotels-Voco-Madrid-Retiro.h46910.Hotel-Information) Retiro 8.8/10 Excellent (1004) "Enjoyed our stay." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Roger CA $144 CA $158 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Madrid-Hotels-Voco-Madrid-Retiro.h46910.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/25700/25620/ee513b44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/25700/25620/b244436f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/25700/25620/92c7efd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/25700/25620/05054966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Gran Versalles [](https://www.expedia.ca/Madrid-Hotels-Hotel-Gran-Versalles.h25620.Hotel-Information) Chamberí 8.8/10 Excellent (1001) "Perfect hotel and perfect location, at a great price. They even upgraded us to a better room without additional cost. I wild totally recommend this hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ROBERTO CA $161 CA $177 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Madrid-Hotels-Hotel-Gran-Versalles.h25620.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/564200/564180/cf85cac6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/570000/564200/564180/6222a531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/570000/564200/564180/71fbf746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/570000/564200/564180/b33d0995.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Rome Airport [](https://www.expedia.ca/Rome-Hotels-Hilton-Rome-Airport.h564180.Hotel-Information) Fiumicino 8.0/10 Very good (3150) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen CA $249 CA $287 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Rome-Hotels-Hilton-Rome-Airport.h564180.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Mediterranean-Region-Hotels.s40-0-d844522342175883264.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Mediterranean-Region-Hotels.s40-0-d844522342175883264.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Mediterranean Region. ![Grand Hyatt Athens](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/dbfe795f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Grand Hyatt Athens 115, Syngrou Avenue Athens Attica CA $147 CA $174 total Jan 2 - Jan 3, 2026 includes taxes & fees 8.6/10 Excellent! (994 reviews) [](https://expedia.ca/Athens-Hotels-Grand-Hyatt-Athens.h21031.Hotel-Information) ![Lamaro Hotel](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/a07cf64a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Lamaro Hotel Avenida Catedral, 7 Barcelona CA $300 CA $357 total Dec 14 - Dec 15 includes taxes & fees 9.4/10 Exceptional! (1,811 reviews) [](https://expedia.ca/Barcelona-Hotels-Hotel-Colon-Barcelona.h3388.Hotel-Information) ![Hyatt Regency Barcelona Tower](https://images.trvl-media.com/lodging/2000000/1340000/1338000/1337977/3f36a705_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hyatt Regency Barcelona Tower Gran Via 144 L'Hospitalet de Llobregat CA $212 CA $243 total Dec 14 - Dec 15 includes taxes & fees 8.8/10 Excellent! (1,004 reviews) [](https://expedia.ca/Barcelona-Hotels-Hyatt-Regency-Barcelona-Tower.h1337977.Hotel-Information) Still don't see what you're looking for? [See all properties in Mediterranean Region.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=12%2F12%2F2025&endDate=13%2F12%2F2025®ionId=844522342175883264&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=12%2F12%2F2025&endDate=13%2F12%2F2025®ionId=844522342175883264&star=40&star=40&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=12%2F12%2F2025&endDate=13%2F12%2F2025®ionId=844522342175883264&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=12%2F12%2F2025&endDate=13%2F12%2F2025®ionId=844522342175883264&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=12%2F12%2F2025&endDate=13%2F12%2F2025®ionId=844522342175883264&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=12%2F12%2F2025&endDate=13%2F12%2F2025®ionId=844522342175883264&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Mediterranean Region During your stay in Mediterranean Region, you can discover things to see and do in the local area. [See all hotels in Mediterranean Region](https://www.expedia.ca/Hotel-Search?startDate=2025-12-25&endDate=2025-12-26&adults=2®ionId=844522342175883264) ![Mazarrón, Spain](https://images.trvl-media.com/place/553248633936349954/597750c4-7c4e-4a36-b33c-904705e647c4.jpg?impolicy=fcrop&w=900&h=599&p=1&q=high) ## Top Mediterranean Region Hotel Reviews ![UNA Hotels Decò Roma](https://images.trvl-media.com/lodging/3000000/2230000/2222500/2222425/f97ca989_y.jpg) ### UNA Hotels Decò Roma 10/10 Excellent "Ac cool breakfast good " [](https://expedia.ca/Rome-Hotels-UNAHOTELS-Deco-Roma.h2222425.Hotel-Information) ![Hotel Regina](https://images.trvl-media.com/lodging/2000000/1180000/1170200/1170158/e8709f28_y.jpg) ### Hotel Regina 10/10 Excellent "Great hotel in walking distance to the major attractions. Beautifully decorated for Christmas inside and outside. The room was clean and not too small. Delicious breakfast, one of the best ones we’ve had in the hotels when traveling. There’s a restaurant next to the hotel as well as coffee shops and shopping. Will stay again, highly recommend. " [](https://expedia.ca/Madrid-Hotels-Hotel-Regina.h1170158.Hotel-Information) ![Hotel Riu Plaza España](https://images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/42fcab3f_y.jpg) ### Hotel Riu Plaza España 10/10 Excellent "Great hotel, friendly staff, close to everything , amazing food and wonderful breakfast! " [](https://expedia.ca/Madrid-Hotels-Hotel-Riu-Plaza-Espana.h29345493.Hotel-Information) ![Radisson Blu Hotel](https://images.trvl-media.com/lodging/1000000/530000/524600/524550/907de448_y.jpg) ### Radisson Blu Hotel 10/10 Excellent "Excellent stay" [](https://expedia.ca/Lisbon-District-Hotels-Radisson-Blu-Hotel.h524550.Hotel-Information) ![Barcelona Airport Hotel](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/ab2f831e_y.jpg) ### Barcelona Airport Hotel 10/10 Excellent "It was great!" [](https://expedia.ca/Barcelona-Hotels-Barcelona-Airport-Hotel.h1439964.Hotel-Information) ![Hotel Emperador](https://images.trvl-media.com/lodging/1000000/10000/1000/915/2f47a159_y.jpg) ### Hotel Emperador 10/10 Excellent "Bello y bien ubicado " [](https://expedia.ca/Madrid-Hotels-Hotel-Emperador.h915.Hotel-Information) ![The Hive Hotel](https://images.trvl-media.com/lodging/25000000/24470000/24463300/24463268/ec6c185a_y.jpg) ### The Hive Hotel 10/10 Excellent "Quiet comfortable and great location " [](https://expedia.ca/Rome-Hotels-The-Hive-Hotel.h24463268.Hotel-Information) ![Hotel Acta Moa- New Opening](https://images.trvl-media.com/lodging/118000000/117140000/117137400/117137301/1fd8b13a_y.jpg) ### Hotel Acta Moa- New Opening 10/10 Excellent "It is a Brand New place! Very Good! Breakfast excelente and very excelente price!" [](https://expedia.ca/Lisbon-District-Hotels-Acta-Moa.h117137301.Hotel-Information) ![Hotel Delle Nazioni](https://images.trvl-media.com/lodging/1000000/60000/54200/54154/104d793e_y.jpg) ### Hotel Delle Nazioni 10/10 Excellent "Hotel Delle Nazioni is unbeatable. The rooms are modern and spotless, the location is perfect, and the service is always excellent. The price, the breakfast, the comfort everything is consistently amazing. Whenever I return, this is the only place I want to stay. " [](https://expedia.ca/Rome-Hotels-Hotel-Delle-Nazioni.h54154.Hotel-Information) ## Find out more about Mediterranean Region If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Mediterranean Region are calling your name. Known for providing first-rate service in amazing locations, each of the Mediterranean Region 4 Stars hotels lets discerning travelers bask in an unforgettable experience. Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day. It’s all waiting for you at the top four star hotels in Mediterranean Region. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Mediterranean Region, , neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Mediterranean Region hotels with 4 Stars provide everything you need to unwind in style.