Title: 4 Stars Hotels in Eastern Panama, Panama  - Find Cheap Eastern Panama Hotels With 4 Stars | Expedia.ca

 

[Eastern Panama Travel Guide](https://expedia.ca/Eastern-Panama.dx6246114)[Hotels in Eastern Panama](https://expedia.ca/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Vacation Rentals in Eastern Panama](https://expedia.ca/Eastern-Panama-Vacation-Rentals.d6246114.Travel-Guide-VacationRentals)[Flights to Eastern Panama](https://expedia.ca/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Things to do in Eastern Panama](https://expedia.ca/Things-To-Do-In-Eastern-Panama.d6246114.Travel-Guide-Activities)[Eastern Panama Car Rentals](https://expedia.ca/Car-Rentals-In-Eastern-Panama.d6246114.Car-Rental-Guide)[Eastern Panama Vacation Packages](https://expedia.ca/Eastern-Panama.d6246114.Destination-Travel-Guides)

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# 4 Stars Hotels in Eastern Panama, Panama

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## Check availability on Eastern Panama 4 Star Hotels

Tonight

[Oct 17 - Oct 18](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2025-10-17&endDate=2025-10-18&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2025-10-18&endDate=2025-10-19&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Eastern Panama 4 Star Hotels

![Luxury Suite](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/20f9a672.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/ece402e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, Ocean View | Terrace/patio](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/4275f8e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/36fec884.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ordovician Beach Resort

Isla Grande

10/10

Exceptional

(3)

"Amazing piece of Caribbean paradise! The staff went above and beyond to make us feel special."

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Francisco

[](https://www.expedia.ca/Ordovician-Beach-Resort.h103761591.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/108000000/107720000/107714100/107714077/956c2c4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Suite, Mountain View](https://images.trvl-media.com/lodging/108000000/107720000/107714100/107714077/14e84dc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/108000000/107720000/107714100/107714077/cc15fa52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/108000000/107720000/107714100/107714077/65c1a6f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mandalas Ecolodge

Caimitillo

[](https://www.expedia.ca/Caimitillo-Hotels-Mandalas-Ecolodge.h107714077.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4320000/4313000/4312945/a37c3663.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite](https://images.trvl-media.com/lodging/5000000/4320000/4313000/4312945/1caaad3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/5000000/4320000/4313000/4312945/a31596fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/5000000/4320000/4313000/4312945/849612f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### El Otro Lado

Portobelo

9.8/10

Exceptional

(8)

"Amazing.. Amazing. You need extra words, We loved it. We loved it.Amazing.. Amazing. You need extra words, We loved it. We loved it. Amazing.. Amazing. You need extra words, We loved it. We loved it. "

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jacob

[](https://www.expedia.ca/Portobelo-Hotels-El-Otro-Lado.h4312945.Hotel-Information)

![Premium bedding, down comforters, individually decorated](https://images.trvl-media.com/lodging/38000000/37040000/37032000/37031981/94721000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/38000000/37040000/37032000/37031981/576244d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![30-inch TV with premium channels, DVD player](https://images.trvl-media.com/lodging/38000000/37040000/37032000/37031981/5edecc13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premier Apartment, Bay View | Bathroom](https://images.trvl-media.com/lodging/38000000/37040000/37032000/37031981/838e9b19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Portobello Historico

Portobelo

[](https://www.expedia.ca/Portobelo-Hotels-Portobello-Historico.h37031981.Hotel-Information)

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## Learn more about Eastern Panama

Explore attractions like Cayos Holandeses and Chagres National Park as you discover things to see and do in Eastern Panama.

[See all hotels in Eastern Panama](https://www.expedia.ca/Hotel-Search?startDate=2025-11-01&endDate=2025-11-02&adults=2&regionId=6246114)

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## Top Eastern Panama Hotel Reviews

## Find out more about Eastern Panama

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Eastern Panama are calling your name. Known for providing first-rate service in amazing locations, each of the Eastern Panama 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Eastern Panama. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Eastern Panama, Panama, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Eastern Panama hotels with 4 Stars provide everything you need to unwind in style.

## Frequently asked questions

### How much does it cost to stay in a 4-star hotel in Eastern Panama?

> With Expedia's handy search filters, scoring a terrific deal on a 4-star hotel in Eastern Panama just got easier. Start by entering your chosen arrival date and length of your getaway. Then list the results by price and pick the option that best suits your style and budget.
> 
>   
> 
> -   Search for the lowest price

### What's the difference between 5-star and 4-star hotels in Eastern Panama?

> Give yourself the luxury treatment during your Eastern Panama vacation by staying at a 4-star hotel. As well as featuring upscale surroundings, these properties are typically packed with amenities like bathrobes, large beds and more. A 5-star hotel will go above and beyond to make your stay an even more lavish and memorable one. Concierge assistance, elegant furnishings and gourmet dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.

### Does Eastern Panama have any 4-star all-inclusive resorts?

> Use our "All inclusive" filter to search for your next escape in Eastern Panama where just about everything is taken care of, from your room to your food, activities and entertainment. We can also help you find standard 4-star stays in and around this leading destination.