Title: Book the Best Wytheville SPA Resorts from CA $165 - Spa Hotels in Wytheville, VA | Expedia.ca [Wytheville Travel Guide](https://expedia.ca/Wytheville.dx6056934)[Hotels in Wytheville](https://expedia.ca/Wytheville-Hotels.d6056934.Travel-Guide-Hotels)[Vacation Rentals in Wytheville](https://expedia.ca/Wytheville-Vacation-Rentals.d6056934.Travel-Guide-VacationRentals)[Wytheville Car Rentals](https://expedia.ca/Car-Rentals-In-Wytheville.d6056934.Car-Rental-Guide)[Wytheville Vacation Packages](https://expedia.ca/Wytheville.d6056934.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/fd2333620ffa5a37a1c42ce74b472c19.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Meng Fan # Find Spa Hotels in Wytheville, VA from CA $165 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Wytheville Spa Hotels Tonight [Sep 28 - Sep 29](https://www.expedia.ca/Hotel-Search?regionId=6056934&startDate=2025-09-28&endDate=2025-09-29&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 29 - Sep 30](https://www.expedia.ca/Hotel-Search?regionId=6056934&startDate=2025-09-29&endDate=2025-09-30&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6056934&startDate=2025-10-03&endDate=2025-10-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6056934&startDate=2025-10-10&endDate=2025-10-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Wytheville Spa Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/564000/563983/84b3cd41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/570000/564000/563983/93e9f41b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/564000/563983/39b2fca5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/570000/564000/563983/754a1adc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Hillsville I-77 Hillsville 9.2/10 Wonderful (1016) "I will definitely stay here again when traveling through here again." CA $144 CA $165 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Hillsville-Hotels-Comfort-Inn-Suites-Hillsville-I-77.h563983.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-12&endDate=2025-10-13®ionId=6056934&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Wytheville Hotel Reviews ![Country Inn & Suites by Radisson, Wytheville, VA](//images.trvl-media.com/lodging/2000000/1900000/1892100/1892033/faddabf5_y.jpg) ### Country Inn & Suites by Radisson, Wytheville, VA 10/10 Excellent "Very easy nice check inn" [](https://expedia.ca/Wytheville-Hotels-Country-Inn-Suites-By-Radisson.h1892033.Hotel-Information) ![Holiday Inn Express and Suites Wytheville by IHG](//images.trvl-media.com/lodging/5000000/4960000/4954500/4954449/c777bb33_y.jpg) ### Holiday Inn Express and Suites Wytheville by IHG 10/10 Excellent "Clean rooms felt safe" [](https://expedia.ca/Wytheville-Hotels-Holiday-Inn-Express-And-Suites-Wytheville.h4954449.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Wytheville? > Forget the stress of everyday life and book yourself a lush spa hotel. Travelers highly recommend the restaurants in Wytheville. Enjoy the entertainment choices and mountain views during your vacation. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your vacation. ### What's there to see and do in Wytheville? > Enjoy all that Wytheville has to offer when you visit Wytheville Meeting Center, Wohlfahrt Haus Dinner Theatre, and Galewinds Amusement Park. If you have extra time while you're in the area, you might want to see Big Walker Lookout and Jefferson National Forest. ### What is a Wytheville spa hotel? > Spa hotels in Wytheville provide lodging and have an on-site spa which offers services including massages as well as body treatments. Some also offer in-room treatments. 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