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Check prices for these dates

Next weekend
Aug 15 - Aug 17
In two weeks
Aug 22 - Aug 24
In one month
Sep 5 - Sep 7
In two months
Oct 3 - Oct 5

Browse Select Wykoff Vacation Homes

The Hen House Retreat - A Comfortable Place to Roost
Stroll through the charming garden, surrounded by lush plants and flowers, to the inviting porch with a comfortable bench.

The Hen House Retreat - A Comfortable Place to Roost

9.8 out of 10, Exceptional, (81)
"We enjoyed taking it easy watching some movies and crafting together for the weekend."
The price is CA $223
CA $273 total
includes taxes & fees
Aug 13 - Aug 14
The Hen House Retreat - A Comfortable Place to Roost
Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic
Enjoy meals in the kitchen with stainless steel appliances, a dining area, and a patio view.

Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic

10.0 out of 10, Exceptional, (31)
"This home is Central to the Mayo clinic The home is very nice and clean with everything you could possibly need for your stay. We would be back in a few months and definitely be staying here"
Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Enjoy cooking in this well-equipped kitchen with a double oven, microwave, and ample cabinetry.

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

10.0 out of 10, Exceptional, (90)
"perfect location perfect house. "
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Recliners. Single Level Living. Walk in shower.
Enjoy cooking in this well-equipped kitchen with a gas stove, refrigerator, and ample cabinetry.

Recliners. Single Level Living. Walk in shower.

10.0 out of 10, Exceptional, (21)
"Property is as described worked well for us."
Recliners. Single Level Living. Walk in shower.
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
Interior

Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

9.4 out of 10, Exceptional, (12)
"We enjoyed our stay and appreciated how easy it was to reserve and communicate with the host! Thank you so much!"
The price is CA $137
CA $376 total
includes taxes & fees
Aug 18 - Aug 19
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
Park in the Garage and Walk to Mayo Clinic
Relax in comfort with a bench and two armchairs, perfect for unwinding in a peaceful space.

Park in the Garage and Walk to Mayo Clinic

10.0 out of 10, Exceptional, (61)
"Cozy house that quick and easy to get to and from the hospital. Easy access to restaurants and all the main amenities that you need. "
Park in the Garage and Walk to Mayo Clinic
"Walden Pond" Adventure Amidst 44 Private Acres
Staircase leads to an upper level with rustic charm.

"Walden Pond" Adventure Amidst 44 Private Acres

10.0 out of 10, Exceptional, (132)
"Enjoyed our stay, good communication."
"Walden Pond" Adventure Amidst 44 Private Acres
Single Level Living with Comfortable Recliners
Enjoy meals in this kitchen with a sink, refrigerator, oven, and microwave, opening into a dining area with a view of the living room.

Single Level Living with Comfortable Recliners

10.0 out of 10, Exceptional, (33)
"It was really nice and clean"
Single Level Living with Comfortable Recliners
Harmony Home w/ Fire Pit: 5 Mi to Niagara Cave!
Compact kitchen with central island, sink, microwave, and stove, featuring light-colored cabinetry and a tiled backsplash.

Harmony Home w/ Fire Pit: 5 Mi to Niagara Cave!

9.6 out of 10, Exceptional, (8)
"House was very clean and full of amenities and instructions to make the stay easy and useful. Would stay here again in a heartbeat. "
Harmony Home w/ Fire Pit: 5 Mi to Niagara Cave!
Silver Lake Oasis
Cross a serene stone bridge over a peaceful pond surrounded by lush greenery and lily pads.

Silver Lake Oasis

9.6 out of 10, Exceptional, (36)
"A nice little place, well kept and just as advertised."
Silver Lake Oasis
Charming 4-bedroom house with 3 king/1 full beds, 2 full baths, AC, Wifi, Patio
Stucco exterior home with a front door, two windows, and a driveway.

Charming 4-bedroom house with 3 king/1 full beds, 2 full baths, AC, Wifi, Patio

10.0 out of 10, Exceptional, (6)
"A lovely home that was so comfortable for us to stay in "
The price is CA $219
CA $623 total
includes taxes & fees
Aug 14 - Aug 15
Charming 4-bedroom house with 3 king/1 full beds, 2 full baths, AC, Wifi, Patio
The Best of Southwest Rochester, MN
Relax in this inviting living room with a sofa, armchairs, and a small table.

The Best of Southwest Rochester, MN

The Best of Southwest Rochester, MN
New Listing! Bella Casa! Whole house downtown Rochester. (Near Mayo Clinic)
Relax in comfort with a large bed, a wall-mounted nightstand, and a cozy chair.

New Listing! Bella Casa! Whole house downtown Rochester. (Near Mayo Clinic)

9.8 out of 10, Exceptional, (39)
"Communication was fantastic, lovely house! "
New Listing! Bella Casa! Whole house downtown Rochester. (Near Mayo Clinic)
Entertainment for the whole family. Sleeps up to 10.
Enjoy cooking in the well-equipped kitchen with a central island, stainless steel appliances, and a dining area with a wooden table.

Entertainment for the whole family. Sleeps up to 10.

9.8 out of 10, Exceptional, (7)
"The house was very clean, with everything you needed. I loved the cinema and the communication with the owner, who was excellent, very friendly. I sincerely recommend it. The area was very quiet."
Entertainment for the whole family. Sleeps up to 10.
Beautiful Big House in a quaint little Town!
Kitchen features a double sink, microwave, oven, toaster, and dishwasher.

Beautiful Big House in a quaint little Town!

9.2 out of 10, Wonderful, (13)
"The house suited our needs."
Beautiful Big House in a quaint little Town!
Magical Nest Hideaway
Stunning two-story residence with a spacious balcony and beautifully maintained garden.

Magical Nest Hideaway

10.0 out of 10, Exceptional, (121)
"Stayed a couple days. Nice location and friendly owners. "
Magical Nest Hideaway
New Luxurious 5-BR Retreat with Gym & Game Area
Relax on the balcony with a comfortable bench and a wicker chair, taking in the view of the surrounding houses.

New Luxurious 5-BR Retreat with Gym & Game Area

10.0 out of 10, Exceptional, (26)
"Beautiful home, pristine condition, fun stay for a family group"
New Luxurious 5-BR Retreat with Gym & Game Area
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Enjoy cooking in this well-equipped kitchen with a central island, microwave, stove, and refrigerator.

☆Dee Dee's Den: A Dharma Dwellings Parent Company☆

10.0 out of 10, Exceptional, (40)
"Great space for full family "
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Lux 3BR Cozy Nook I Mins to Mayo & Dwtwn I Pets
Stunning single-story home with a gabled roof and welcoming entrance.

Lux 3BR Cozy Nook I Mins to Mayo & Dwtwn I Pets

9.6 out of 10, Exceptional, (4)
"Very cute and well maintained. We would definitely stay again. "
The price is CA $244
CA $623 total
includes taxes & fees
Aug 15 - Aug 16
Lux 3BR Cozy Nook I Mins to Mayo & Dwtwn I Pets
Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.
Situated in a residential area, this cozy home features a front porch and a grassy lawn.

Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.

10.0 out of 10, Exceptional, (8)
"House was exactly as described, very clean, quiet and cozy. Was perfect for my short stay visiting family. Would absolutely stay again. "
The price is CA $106
CA $313 total
includes taxes & fees
Aug 18 - Aug 19
Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Wykoff Hotel Reviews

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

10/10 Excellent
"Rooms very nice"
Lily 1-night trip
Posted 2 days ago
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's