Title: Hotels by Marriott Hotels & Resorts in Wykoff from CA $268 | Expedia.ca [Wykoff Travel Guide](https://expedia.ca/Wykoff.dx3000443967)[Hotels in Wykoff](https://expedia.ca/Wykoff-Hotels.d3000443967.Travel-Guide-Hotels)[Vacation Rentals in Wykoff](https://expedia.ca/Wykoff-Vacation-Rentals.d3000443967.Travel-Guide-VacationRentals)[Flights to Wykoff](https://expedia.ca/Cheap-Flights-To-Wykoff.d3000443967.Travel-Guide-Flights)[Wykoff Car Rentals](https://expedia.ca/Car-Rentals-In-Wykoff.d3000443967.Car-Rental-Guide)[Wykoff Vacation Packages](https://expedia.ca/Wykoff.d3000443967.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 23 - Jan 24](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2026-01-23&endDate=2026-01-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 24 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2026-01-24&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Wykoff Marriott Hotels & Resorts ![City view from property](https://images.trvl-media.com/lodging/1000000/10000/4000/3948/50a69e5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/4000/3948/7d048b62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4000/3948/3d74b192.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/4000/3948/c1a0e9f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Rochester Mayo Clinic [](https://www.expedia.ca/Rochester-Hotels-Marriott-Rochester-Mayo-Clinic.h3948.Hotel-Information) Downtown Rochester 8.4/10 Very good (529 reviews) "it was a fantastic " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul CA $233 CA $268 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/Rochester-Hotels-Marriott-Rochester-Mayo-Clinic.h3948.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-06&endDate=2026-02-07®ionId=3000443967&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FWykoff-Hotels-Marriott-Hotels-Resorts.0-0-d3000443967--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FWykoff-Hotels-Marriott-Hotels-Resorts.0-0-d3000443967--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) ## Top Wykoff Hotel Reviews ![Holiday Inn Express Rochester South - Mayo Area by IHG](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/62a372dd_y.jpg) ### Holiday Inn Express Rochester South - Mayo Area by IHG 10/10 Excellent "." [](https://expedia.ca/Rochester-Hotels-Comfort-Suites.h2184971.Hotel-Information) ![SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c_y.jpg) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys 10/10 Excellent "When I told my husband where we were staying he was not pleased at all. He wanted something closer to the hospital.When we got there he went and checked us in and check out the room he was very pleased. There was hot drinks always ready. The room was very clean and comfortable. The staff was extremely accommodating.We will stay there again. We left to go back home and stayed in another hotel and the second we walked in the room we both said this is not the SpringHill Suites. SpringHill Suites thank you for a memorable experience." [](https://expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) ![Home2 Suites by Hilton Rochester Mayo Clinic Area](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/444e106b_y.jpg) ### Home2 Suites by Hilton Rochester Mayo Clinic Area 10/10 Excellent "It has been a Great stay & very clean & quiet! Staff has been great also. " [](https://expedia.ca/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information) ![Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys](https://images.trvl-media.com/lodging/11000000/10950000/10947300/10947270/9bad372e_y.jpg) ### Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys 10/10 Excellent "Great execution of all facets of a good hotel." [](https://expedia.ca/Rochester-Hotels-Fairfield-Inn-Suites-Rochester-Mayo-Clinic-AreaSt-Marys.h10947270.Hotel-Information) ![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "Amazing all around! " [](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![The Berkman](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/50c22b07_y.jpg) ### The Berkman 10/10 Excellent "Amazing" [](https://expedia.ca/Rochester-Hotels-Berkman-Hotel.h46291477.Hotel-Information) ![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG 10/10 Excellent "Love the restaurant… truffle fries are the best!!! Staff is great!!!" [](https://expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Hyatt House Rochester/Mayo Clinic Area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1_y.jpg) ### Hyatt House Rochester/Mayo Clinic Area 10/10 Excellent "All the above!! Surprisingly pleasant and exceeded expectations. Expedia value was an extra bonus. " [](https://expedia.ca/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information) ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "The amenities and the great customer service. 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