Title: Hotels by Hilton Hotels in Wykoff from CA $274 | Expedia.ca [Wykoff Travel Guide](https://expedia.ca/Wykoff.dx3000443967)[Hotels in Wykoff](https://expedia.ca/Wykoff-Hotels.d3000443967.Travel-Guide-Hotels)[Vacation Rentals in Wykoff](https://expedia.ca/Wykoff-Vacation-Rentals.d3000443967.Travel-Guide-VacationRentals)[Flights to Wykoff](https://expedia.ca/Cheap-Flights-To-Wykoff.d3000443967.Travel-Guide-Flights)[Wykoff Car Rentals](https://expedia.ca/Car-Rentals-In-Wykoff.d3000443967.Car-Rental-Guide)[Wykoff Vacation Packages](https://expedia.ca/Wykoff.d3000443967.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 17 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2026-01-17&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 18 - Jan 19](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2026-01-18&endDate=2026-01-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Wykoff Hilton Hotels ![Presidential Suite, Multiple Beds | Living area](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/c7a0b093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/b1555778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch LCD TV with satellite channels, TV](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/ef0f8d85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/86063f91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Rochester Mayo Clinic Area [](https://www.expedia.ca/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information) Downtown Rochester 9.6/10 Exceptional (553 reviews) "Very courteous staff, loved the valet guy!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jean CA $238 CA $274 total includes taxes & fees Feb 7 - Feb 8 [](https://www.expedia.ca/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-31&endDate=2026-02-01®ionId=3000443967&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FWykoff-Hotels-Hilton-Hotels.0-0-d3000443967--bHiltonHotels.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FWykoff-Hotels-Hilton-Hotels.0-0-d3000443967--bHiltonHotels.Travel-Guide-Filter-Hotels) ## Top Wykoff Hotel Reviews ![SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c_y.jpg) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys 10/10 Excellent "Clean room...helpful staff. Thank you for a great experience. " [](https://expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) ![Home2 Suites by Hilton Rochester Mayo Clinic Area](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/444e106b_y.jpg) ### Home2 Suites by Hilton Rochester Mayo Clinic Area 10/10 Excellent "The room was clean. The staff was excellent. We enjoyed our stay." [](https://expedia.ca/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information) ![Hyatt House Rochester/Mayo Clinic Area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1_y.jpg) ### Hyatt House Rochester/Mayo Clinic Area 10/10 Excellent "The electrical outlet plugs in the room were worn out. Most would not hold a plug. Plug in their hair dryer or the brick to charge my phone and it would just drop out of the socket. Frustrating and especially in the bathroom NOT SAFE. The room was worn but meticulously clean. " [](https://expedia.ca/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information) ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg) ### Brentwood Inn & Suites 10/10 Excellent "Very convenient to mayo and dt area! Great value!" [](https://expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "The room was spotless, the staff very friendly, breakfast more than needed, coffee the best of anyplace we've stayed. " [](https://expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![The Berkman](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/50c22b07_y.jpg) ### The Berkman 10/10 Excellent "The room was amazing, spacious, nicely decorated, super clean, complete kitchen, bedroom separated from living… High quality finishes. Very good location accross the street from Mayo. " [](https://expedia.ca/Rochester-Hotels-Berkman-Hotel.h46291477.Hotel-Information) ![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG 10/10 Excellent "Property was excellent. " [](https://expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "Clean and nice rooms" [](https://expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg) ### Hampton Inn Rochester-South 10/10 Excellent "Room was very clean. Everything was very good" [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - More ways to book - [4 Star Hotels in Stewartville ](https://www.expedia.ca/4Star-Stewartville-Hotels.s40-0-d183438.Travel-Guide-Filter-Hotels) - [Hyatt Hotels in Apple Valley ](https://www.expedia.ca/Apple-Valley-Hotels-Hyatt-Hotels.0-0-d6003--bHyattHotels.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Bancroft ](https://www.expedia.ca/Bancroft-Minneapolis-St-Paul-Hotels-Hilton-Hotels.0-n553248635976472057-0--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Bayport ](https://www.expedia.ca/Bayport-Hotels-Hilton-Hotels.0-0-d3000442965--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Accor Hotels in Bloomington ](https://www.expedia.ca/Bloomington-Hotels-Accor-Hotels.0-0-d6287--bAccorHotels.Travel-Guide-Filter-Hotels) - [Best Western Hotels in Bloomington ](https://www.expedia.ca/Bloomington-Hotels-Best-Western.0-0-d6287--bBestWestern.Travel-Guide-Filter-Hotels) - 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