Title: Book the Best BUSINESS Hotels in Winston-Salem in 2025 | Expedia.ca [Hotels in Winston-Salem](https://expedia.ca/Winston-Salem-Hotels.d1605.Travel-Guide-Hotels)[Vacation Rentals in Winston-Salem](https://expedia.ca/Winston-Salem-Vacation-Rentals.d1605.Travel-Guide-VacationRentals)[Flights to Winston-Salem](https://expedia.ca/Cheap-Flights-To-Winston-Salem.d1605.Travel-Guide-Flights)[Things to do in Winston-Salem](https://expedia.ca/Things-To-Do-In-Winston-Salem.d1605.Travel-Guide-Activities)[Winston-Salem Car Rentals](https://expedia.ca/Car-Rentals-In-Winston-Salem.d1605.Car-Rental-Guide)[Winston-Salem Vacation Packages](https://expedia.ca/Winston-Salem.d1605.Destination-Travel-Guides) ![Winston - Salem showing a house, heritage elements and interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/82000/82242-Winston.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Winston-Salem, NC from CA $123 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Winston-Salem Business Hotels Tonight [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=1605&startDate=2025-10-16&endDate=2025-10-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Oct 17 - Oct 18](https://www.expedia.ca/Hotel-Search?regionId=1605&startDate=2025-10-17&endDate=2025-10-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=1605&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=1605&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Winston-Salem Business Hotels ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/26500/26487/98220637.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/1000000/30000/26500/26487/e8cc7313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/30000/26500/26487/468ec72a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26500/26487/eb49a547.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Historic Brookstown Inn, Trademark Collection by Wyndham Winston-Salem 9.6/10 Exceptional (1010) "Loved the large rooms and all the hospitality and history of the place. " CA $171 CA $193 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Winston-Salem-Hotels-The-Historic-Brookstown-Inn.h26487.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3060000/3052600/3052554/306cf64f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3060000/3052600/3052554/c3804171.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3060000/3052600/3052554/db22ed4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3060000/3052600/3052554/34553f1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Winston-Salem/University Area, NC Winston-Salem 9.0/10 Wonderful (1007) "I LOVED everything about my stay at Hampton Inn." CA $154 CA $174 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Winston-Salem-Hotels-Hampton-Inn-Suites-Winston-SalemUniversity-Area.h3052554.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2780000/2774700/2774641/12e4c384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch LCD TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/3000000/2780000/2774700/2774641/31804569.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2780000/2774700/2774641/72ab3d34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2780000/2774700/2774641/c306df28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Springhill Suites by Marriott Winston-Salem Hanes Mall Winston-Salem 9.0/10 Wonderful (1007) "Like every Springhill suites I’ve stayed at, this one was wonderful. Clean, open design, excellent breakfast. " CA $150 CA $170 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Winston-Salem-Hotels-Springhill-Suites-By-Marriott-Winston-Salem-Hanes-Mall.h2774641.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/14000000/13190000/13181300/13181289/44441b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; French cuisine ](https://images.trvl-media.com/lodging/14000000/13190000/13181300/13181289/00d421ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/14000000/13190000/13181300/13181289/37c81d82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/14000000/13190000/13181300/13181289/9657c278.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kimpton Cardinal Hotel by IHG Winston-Salem 9.0/10 Wonderful (1001) "The hotel is lovely! The staff were friendly and helpful. The restaurant was amazing! I would definitely stay again!" CA $210 CA $237 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Winston-Salem-Hotels-Kimpton-Cardinal-Hotel.h13181289.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12000/11901/7de40e3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12000/11901/33380a1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/12000/11901/08b3e090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/12000/11901/f8428b82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Hanes Mall Hotel Winston-Salem 7.6/10 Good (1006) "Great stay " CA $109 CA $123 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Winston-Salem-Hotels-Best-Western-Plus-Hanes-Mall-Hotel.h11901.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/810000/802600/802537/182391e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/810000/802600/802537/fd0c1046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/810000/802600/802537/f5f15af9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/802600/802537/0c37bff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Exp Winston Salem by IHG Winston-Salem 8.4/10 Very good (836) "Property and staff were great. Surrounding area had many shopping options" CA $122 CA $138 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Winston-Salem-Hotels-Holiday-Inn-Exp-Winston-Salem.h802537.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/8600/8533/97b1f25b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9 AM to 9 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/8600/8533/4cd1ef05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8600/8533/w7360h4908x0y0-ceb51a06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/8600/8533/ab78e044.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Winston-Salem Medical Center Area by IHG Winston-Salem 8.4/10 Very good (982) "The staff was very nice. The hotel was very clean and convenient. The rooms were very comfortable. " CA $134 CA $151 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Winston-Salem-Hotels-Holiday-Inn-Express-Winston-Salem-Downtown-West.h8533.Hotel-Information) ![Standard Room, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/210000/200700/200636/1519d557.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/210000/200700/200636/8d32a7db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/210000/200700/200636/9faf156f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/210000/200700/200636/ee1f87dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Hanes Mall Winston-Salem 8.8/10 Excellent (1010) "Perfect place for our visit " CA $128 CA $148 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Winston-Salem-Hotels-Comfort-Suites-Hanes-Mall.h200636.Hotel-Information) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/5600/5561/c46a044c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5600/5561/2daee002.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5600/5561/2d111cfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/5600/5561/0b44c388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Winston-Salem Hanes Mall Winston-Salem 9.2/10 Wonderful (1005) "Great location" CA $149 CA $168 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Winston-Salem-Hotels-Hampton-Inn-Winston-Salem-Hanes-Mall.h5561.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/1000000/30000/28400/28378/f835bd0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28400/28378/0ec08122.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/28400/28378/9addc774.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/28400/28378/4c61d9d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Winston Salem - University Winston-Salem 8.4/10 Very good (1003) "Great stay! Staff was very friendly and helpful." CA $147 CA $166 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Winston-Salem-Hotels-DoubleTree-By-Hilton-Hotel-Winston-Salem-University.h28378.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-30&endDate=2025-10-31®ionId=1605&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Winston-Salem Hotel Reviews ![Courtyard by Marriott Winston-Salem University](//images.trvl-media.com/lodging/1000000/10000/8000/7930/a6c41252_y.jpg) ### Courtyard by Marriott Winston-Salem University 10/10 Excellent "Very nice - slightly dated " [](https://expedia.ca/Winston-Salem-Hotels-Courtyard-By-Marriott-Winston-Salem-University.h7930.Hotel-Information) ![Sleep Inn Hanes Mall](//images.trvl-media.com/lodging/1000000/160000/151400/151327/a043f81d_y.jpg) ### Sleep Inn Hanes Mall 10/10 Excellent "It took a week to get my deposit back" [](https://expedia.ca/Winston-Salem-Hotels-Sleep-Inn-Hanes-Mall.h151327.Hotel-Information) ![Best Western Plus University Inn](//images.trvl-media.com/lodging/1000000/10000/5500/5431/c404a8e4_y.jpg) ### Best Western Plus University Inn 10/10 Excellent "Front desk staff is very unprofessional in appearance and demeanor. Appeared panicked dealing with the hotel being heavily booked. Do not like being addressed as "baby' or "honey" even in NC!" [](https://expedia.ca/Winston-Salem-Hotels-Best-Western-Plus-University-Inn.h5431.Hotel-Information) ![The Historic Brookstown Inn, Trademark Collection by Wyndham](//images.trvl-media.com/lodging/1000000/30000/26500/26487/98220637_y.jpg) ### The Historic Brookstown Inn, Trademark Collection by Wyndham 10/10 Excellent "Excellent breakfast, wonderfully clean space and very helpful staff " [](https://expedia.ca/Winston-Salem-Hotels-The-Historic-Brookstown-Inn.h26487.Hotel-Information) ![Courtyard by Marriott Winston-Salem Hanes Mall](//images.trvl-media.com/lodging/1000000/130000/129400/129363/d9aab144_y.jpg) ### Courtyard by Marriott Winston-Salem Hanes Mall 10/10 Excellent "This hotel needs 2 extras luggage carriages. They only have 2 for a 4 floors building. " [](https://expedia.ca/Winston-Salem-Hotels-Courtyard-By-Marriott-Winston-Salem-Hanes-Mall.h129363.Hotel-Information) ![Hawthorne Inn and Conference Center](//images.trvl-media.com/lodging/1000000/200000/190500/190495/da4ccf2c_y.jpg) ### Hawthorne Inn and Conference Center 10/10 Excellent "Terrific value. Great location. One of my most enjoyable stays this year." [](https://expedia.ca/Winston-Salem-Hotels-Hawthorne-Inn-And-Conference-Center.h190495.Hotel-Information) ![HomeTowne Studios by Red Roof Winston-Salem - University Pkwy](//images.trvl-media.com/lodging/1000000/120000/119300/119279/ac86f5b7_y.jpg) ### HomeTowne Studios by Red Roof Winston-Salem - University Pkwy 10/10 Excellent "Nice kitchen" [](https://expedia.ca/Winston-Salem-Hotels-HomeTowne-Studios-By-Red-Roof-Winston-Salem-University-Pkwy.h119279.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Winston-Salem](//images.trvl-media.com/lodging/1000000/290000/287500/287478/8634b3e9_y.jpg) ### La Quinta Inn & Suites by Wyndham Winston-Salem 10/10 Excellent "It’s a great property close to our event and not far from food and shopping " [](https://expedia.ca/Winston-Salem-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Winston-Salem.h287478.Hotel-Information) ![Hampton Inn Winston-Salem Hanes Mall](//images.trvl-media.com/lodging/1000000/10000/5600/5561/c46a044c_y.jpg) ### Hampton Inn Winston-Salem Hanes Mall 10/10 Excellent "The reason I am writing this review is because of one person. I don’t know her last name but her first name is Pat, she is in charge of the kitchen for breakfast. I had misunderstood the time given for breakfast, so when we came down there was nothing left. She saw that I was upset, came over and offered to make us something really quick. She went above and beyond to make sure we were happy. " [](https://expedia.ca/Winston-Salem-Hotels-Hampton-Inn-Winston-Salem-Hanes-Mall.h5561.Hotel-Information) ## Frequently asked questions ### Why book your business-friendly hotel in Winston-Salem with Expedia? > Here at Expedia, our top task is to help you find the ideal stay at the right price. From deluxe, corporate-friendly retreats to affordable motels filled with all the amenities you need, you'll have your next work trip arranged in just a few clicks. ### How can I find cheap business-friendly hotels in Winston-Salem? > When you're travelling for work in Winston-Salem, our "business friendly" filter will help you find the ideal hotel. From free WiFi and included breakfast to computer stations and concierge services, they have the amenities you need to do your job. 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[Wake Forest University Baptist Medical Center](https://www.expedia.ca/Wake-Forest-University-Baptist-Medical-Center-Winston-Salem.d6066217.Vacation-Attraction) - [Winston - Salem Vacations](https://www.expedia.ca/Winston-Salem.d602969.Destination-Travel-Guides) - [Visit Winston - Salem](https://www.expedia.ca/Winston-Salem.dx602969) - [All inclusive Vacation Packages Winston - Salem](https://www.expedia.ca/lp/theme-vacations/all-inclusive-vacations/602969/Winston-Salem) - [Avis Rental Cars in Winston - Salem](https://www.expedia.ca/Avis-Car-Rentals-In-Winston-Salem.d602969-c41.Car-Rental-Guide-Suppliers) - [Car rentals near Wake Forest University Baptist Medical Center](https://www.expedia.ca/Car-Rentals-In-Wake-Forest-University-Baptist-Medical-Center.d6066217.Car-Rental-Guide) - [Car rentals near Winston - Salem](https://www.expedia.ca/Car-Rentals-In-Winston-Salem.d602969.Car-Rental-Guide) - [Ilha Verde Rental Cars in Winston - Salem](https://www.expedia.ca/Ilha-Verde-Car-Rentals-In-Winston-Salem.d602969-c1130.Car-Rental-Guide-Suppliers) - 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