Title: Book the Best BUSINESS Hotels in Wheelersburg in 2026 | Expedia.ca [Hotels in Wheelersburg](https://expedia.ca/Wheelersburg-Hotels.d7601.Travel-Guide-Hotels)[Vacation Rentals in Wheelersburg](https://expedia.ca/Wheelersburg-Vacation-Rentals.d7601.Travel-Guide-VacationRentals)[Wheelersburg Car Rentals](https://expedia.ca/Car-Rentals-In-Wheelersburg.d7601.Car-Rental-Guide)[Wheelersburg Vacation Packages](https://expedia.ca/Wheelersburg.d7601.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/business.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Wheelersburg, OH from CA $105 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Wheelersburg Business Hotels Tonight [Dec 9 - Dec 10](https://www.expedia.ca/Hotel-Search?regionId=7601&startDate=2025-12-09&endDate=2025-12-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 10 - Dec 11](https://www.expedia.ca/Hotel-Search?regionId=7601&startDate=2025-12-10&endDate=2025-12-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=7601&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=7601&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Wheelersburg business-friendly hotels ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/4670d89c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub | Jetted tub](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/3d76b172.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/a0a61de5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/e2ea5317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Wheelersburg Wheelersburg 8.2/10 Very good (311) "The breakfast was very good, there was a variety of items to enjoy. Our rooms were very clean, and check-in was very easy. The property is well taken care of and the staff is friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susanne L. CA $123 CA $137 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Portsmouth-Hotels-Quality-Inn.h34164.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/27200/27143/74dfb1af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/27200/27143/b9331027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Concierge desk](https://images.trvl-media.com/lodging/1000000/30000/27200/27143/a88a036b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27200/27143/w2880h2595x0y12-728a117f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Wheelersburg Wheelersburg 7.0/10 Good (291) "was very nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) garrett [](https://www.expedia.ca/Portsmouth-Hotels-Red-Roof-Inn-Portsmouth-Wheelersburg.h27143.Hotel-Information) ![Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Walk-in Shower;Larger Room)](https://images.trvl-media.com/lodging/1000000/920000/914000/913954/23f0df18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/914000/913954/c1aca0be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/920000/914000/913954/e97936b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/920000/914000/913954/2de980ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western River Cities Russell 8.6/10 Excellent (427) "Staff was nice. Scott helped us out as well as the lady that works overnights. The room was simple and clean. Breakfast was good for what it was. Stayed here last year and will stay next year for Thanksgiving and Christmas as well when we visit family. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lindsay CA $141 CA $160 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Ashland-Hotels-Best-Western-River-Cities.h913954.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/9000000/8710000/8702000/8701954/68a37f70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/9000000/8710000/8702000/8701954/d7d0a5a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/9000000/8710000/8702000/8701954/e72efa29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8710000/8702000/8701954/20f08ebf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Ironton by IHG Ironton 9.4/10 Exceptional (549) "The room was very clean and staff was very polite. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Faith CA $139 CA $157 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Ironton-Hotels-Holiday-Inn-Express-Suites-Ironton.h8701954.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/2623add7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/fd51c93a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/d88101f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/37b6499f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Portsmouth Portsmouth 7.0/10 Good (682) "We loved it and returned each time we are back est." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Saundra CA $101 CA $112 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Portsmouth-Hotels-Super-8-By-Wyndham-Portsmouth.h39801.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/20000000/19390000/19381900/19381810/b049f15d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hiking](https://images.trvl-media.com/lodging/20000000/19390000/19381900/19381810/5e9c2a1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/20000000/19390000/19381900/19381810/c9c11ed9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/20000000/19390000/19381900/19381810/f35a46bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greenbo Lake State Resort Park Greenup 9.0/10 Wonderful (287) "Very nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) D [](https://www.expedia.ca/Ashland-Hotels-Greenbo-Lake-State-Resort-Park.h19381810.Hotel-Information) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/26900/26889/31b4bb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/26900/26889/9ef8c1b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/30000/26900/26889/351d1a45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/30000/26900/26889/17564b42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Jackson Jackson 7.4/10 Good (369) "Food was fresh, staff was very nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Philip CA $106 CA $123 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Chillicothe-Hotels-Days-Inn-By-Wyndham-Jackson.h26889.Hotel-Information) ![Down comforters, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/13000/12951/ea118a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13000/12951/a9e2d37d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13000/12951/12c36e9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/20000/13000/12951/b52c1b66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Piketon near Fairgrounds Piketon 8.2/10 Very good (369) "Great place to stay while visiting our son in Poulsbo." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carole CA $135 CA $153 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/Chillicothe-Hotels-Comfort-Inn.h12951.Hotel-Information) ![Individually furnished, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/520000/519800/519794/ea5c8667.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/520000/519800/519794/aefac9b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/519800/519794/6c22ff9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/519800/519794/225473ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Portsmouth Portsmouth 7.0/10 Good (564) "Property in need of regular maintenance, breakfast was sub par, 4 out 10, however the bed was comfortable. Will try a different property next time I'm in town " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Don CA $94 CA $105 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Portsmouth-Hotels-Quality-Inn-Suites.h519794.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20500/20403/42ca14f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/20500/20403/eea32895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20500/20403/7960e744.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/30000/20500/20403/b1b29d27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Portsmouth Downtown by IHG Portsmouth 8.6/10 Excellent (464) "Clean room, friendly staff. Love this hotel, i stay here every timeni visit family." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cyndi CA $170 CA $190 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Portsmouth-Hotels-Holiday-Inn-Portsmouth-Downtown.h20403.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-23&endDate=2025-12-24®ionId=7601&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Wheelersburg Hotel Reviews ![Super 8 by Wyndham Portsmouth](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/2623add7_y.jpg) ### Super 8 by Wyndham Portsmouth 10/10 Excellent "V " [](https://expedia.ca/Portsmouth-Hotels-Super-8-By-Wyndham-Portsmouth.h39801.Hotel-Information) ![Holiday Inn Portsmouth Downtown by IHG](https://images.trvl-media.com/lodging/1000000/30000/20500/20403/42ca14f7_y.jpg) ### Holiday Inn Portsmouth Downtown by IHG 10/10 Excellent "Clean room and friendly staff " [](https://expedia.ca/Portsmouth-Hotels-Holiday-Inn-Portsmouth-Downtown.h20403.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/60000/56000/55986/0f828bad_y.jpg) ### Quality Inn 10/10 Excellent "Yes" [](https://expedia.ca/Ashland-Hotels-Quality-Inn.h55986.Hotel-Information) ![Best Western River Cities](https://images.trvl-media.com/lodging/1000000/920000/914000/913954/23f0df18_y.jpg) ### Best Western River Cities 10/10 Excellent "Staff was nice. Scott helped us out as well as the lady that works overnights. The room was simple and clean. Breakfast was good for what it was. Stayed here last year and will stay next year for Thanksgiving and Christmas as well when we visit family. " [](https://expedia.ca/Ashland-Hotels-Best-Western-River-Cities.h913954.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/20000/14700/14647/6a921f8c_y.jpg) ### Quality Inn 8/10 Good "Big improvement over last stay there. Room was clean. Coffee was great. No marijuana smell in hallway" [](https://expedia.ca/Chillicothe-Hotels-Quality-Inn.h14647.Hotel-Information) ![Red Roof Inn Jackson, OH](https://images.trvl-media.com/lodging/1000000/920000/911900/911869/dc72906a_y.jpg) ### Red Roof Inn Jackson, OH 10/10 Excellent "Staff was incredibly courteous! " [](https://expedia.ca/Chillicothe-Hotels-Red-Roof-Inn-Jackson.h911869.Hotel-Information) ![Holiday Inn Express & Suites Ironton by IHG](https://images.trvl-media.com/lodging/9000000/8710000/8702000/8701954/68a37f70_y.jpg) ### Holiday Inn Express & Suites Ironton by IHG 10/10 Excellent "Great staff and very clean rooms" [](https://expedia.ca/Ironton-Hotels-Holiday-Inn-Express-Suites-Ironton.h8701954.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/4670d89c_y.jpg) ### Quality Inn 10/10 Excellent "Recently renovated and friendly staff" [](https://expedia.ca/Portsmouth-Hotels-Quality-Inn.h34164.Hotel-Information) ![Quality Inn & Suites Portsmouth](https://images.trvl-media.com/lodging/1000000/520000/519800/519794/ea5c8667_y.jpg) ### Quality Inn & Suites Portsmouth 10/10 Excellent "Everything " [](https://expedia.ca/Portsmouth-Hotels-Quality-Inn-Suites.h519794.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - 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