Title: Book the Best BUSINESS Hotels in Wheelersburg in 2026 | Expedia.ca

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# Find Business Hotels in Wheelersburg, OH from CA $108

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## Check availability on Wheelersburg Business Hotels

Tonight

[Dec 15 - Dec 16](https://www.expedia.ca/Hotel-Search?regionId=7601&startDate=2025-12-15&endDate=2025-12-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Tomorrow

[Dec 16 - Dec 17](https://www.expedia.ca/Hotel-Search?regionId=7601&startDate=2025-12-16&endDate=2025-12-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

This weekend

[Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=7601&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Next weekend

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=7601&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

## Our top choices for Wheelersburg business-friendly hotels

![Gym](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/fcecac02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/d5461db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Jetted Tub | Jetted tub](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/3d76b172.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/8b1239b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Wheelersburg

[](https://www.expedia.ca/Portsmouth-Hotels-Quality-Inn.h34164.Hotel-Information)

Wheelersburg

8.2/10

Very good

(312)

"Happy"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

CA $129

CA $143 total

includes taxes & fees

Dec 22 - Dec 23

[](https://www.expedia.ca/Portsmouth-Hotels-Quality-Inn.h34164.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/27200/27143/w2880h2160x0y1-7e953889.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Concierge desk](https://images.trvl-media.com/lodging/1000000/30000/27200/27143/a88a036b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27200/27143/w2880h2595x0y12-728a117f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/27200/27143/b6a3b6c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Red Roof Inn Wheelersburg

[](https://www.expedia.ca/Portsmouth-Hotels-Red-Roof-Inn-Portsmouth-Wheelersburg.h27143.Hotel-Information)

Wheelersburg

7.0/10

Good

(292)

"was very nice"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

garrett

[](https://www.expedia.ca/Portsmouth-Hotels-Red-Roof-Inn-Portsmouth-Wheelersburg.h27143.Hotel-Information)

![Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Walk-in Shower;Larger Room)](https://images.trvl-media.com/lodging/1000000/920000/914000/913954/70c14cf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/920000/914000/913954/204285d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/920000/914000/913954/075fa43a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/920000/914000/913954/e97936b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western River Cities

[](https://www.expedia.ca/Ashland-Hotels-Best-Western-River-Cities.h913954.Hotel-Information)

Russell

8.6/10

Excellent

(428)

"Staff was nice. Scott helped us out as well as the lady that works overnights. The room was simple and clean. Breakfast was good for what it was. Stayed here last year and will stay next year for Thanksgiving and Christmas as well when we visit family. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lindsay

CA $140

CA $159 total

includes taxes & fees

Jan 2 - Jan 3, 2026

[](https://www.expedia.ca/Ashland-Hotels-Best-Western-River-Cities.h913954.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/20000000/19390000/19381900/19381810/b049f15d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hiking](https://images.trvl-media.com/lodging/20000000/19390000/19381900/19381810/5e9c2a1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/20000000/19390000/19381900/19381810/f35a46bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/20000000/19390000/19381900/19381810/eabc2d46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Greenbo Lake State Resort Park

[](https://www.expedia.ca/Ashland-Hotels-Greenbo-Lake-State-Resort-Park.h19381810.Hotel-Information)

Greenup

9.0/10

Wonderful

(287)

"Very nice stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

D

[](https://www.expedia.ca/Ashland-Hotels-Greenbo-Lake-State-Resort-Park.h19381810.Hotel-Information)

![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/ffe2e28d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/1748f59e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/2623add7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/90787c22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Portsmouth

[](https://www.expedia.ca/Portsmouth-Hotels-Super-8-By-Wyndham-Portsmouth.h39801.Hotel-Information)

Portsmouth

7.0/10

Good

(684)

"I enjoyed my stay here, the staff was very accommodating and friendly. Would definitely stay again! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kaitlyn

CA $101

CA $112 total

includes taxes & fees

Dec 17 - Dec 18

[](https://www.expedia.ca/Portsmouth-Hotels-Super-8-By-Wyndham-Portsmouth.h39801.Hotel-Information)

![Indoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/9000000/8710000/8702000/8701954/00718508.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/9000000/8710000/8702000/8701954/117321d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/9000000/8710000/8702000/8701954/70040a5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/9000000/8710000/8702000/8701954/306cb6ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Ironton by IHG

[](https://www.expedia.ca/Ironton-Hotels-Holiday-Inn-Express-Suites-Ironton.h8701954.Hotel-Information)

Ironton

9.4/10

Exceptional

(552)

"The room was clean. Staff was friendly and helpful, great amenities."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Clover

CA $138

CA $156 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/Ironton-Hotels-Holiday-Inn-Express-Suites-Ironton.h8701954.Hotel-Information)

![Down comforters, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/13000/12951/7112d0ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13000/12951/12c36e9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13000/12951/75f74fcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/13000/12951/2f1d0964.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn Piketon near Fairgrounds

[](https://www.expedia.ca/Chillicothe-Hotels-Comfort-Inn.h12951.Hotel-Information)

Piketon

8.2/10

Very good

(369)

"Great place to stay while visiting our son in Poulsbo."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carole

CA $131

CA $148 total

includes taxes & fees

Jan 14 - Jan 15, 2026

[](https://www.expedia.ca/Chillicothe-Hotels-Comfort-Inn.h12951.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/20500/20403/eea32895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20500/20403/51193068.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/30000/20500/20403/398230dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/30000/20500/20403/312d0110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Portsmouth Downtown by IHG

[](https://www.expedia.ca/Portsmouth-Hotels-Holiday-Inn-Portsmouth-Downtown.h20403.Hotel-Information)

Portsmouth

8.6/10

Excellent

(465)

"Clean room, friendly staff. Love this hotel, i stay here every timeni visit family."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cyndi

CA $169

CA $188 total

includes taxes & fees

Jan 1 - Jan 2, 2026

[](https://www.expedia.ca/Portsmouth-Hotels-Holiday-Inn-Portsmouth-Downtown.h20403.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/1000000/30000/26900/26889/42788093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/26900/26889/31b4bb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/1000000/30000/26900/26889/8dd0bb49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/30000/26900/26889/351d1a45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham Jackson

[](https://www.expedia.ca/Chillicothe-Hotels-Days-Inn-By-Wyndham-Jackson.h26889.Hotel-Information)

Jackson

7.4/10

Good

(370)

"Food was fresh, staff was very nice"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Philip

CA $111

CA $129 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/Chillicothe-Hotels-Days-Inn-By-Wyndham-Jackson.h26889.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/520000/519800/519794/225473ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/520000/519800/519794/aefac9b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Individually furnished, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/520000/519800/519794/e7672a3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/520000/519800/519794/327b173a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn & Suites Portsmouth

[](https://www.expedia.ca/Portsmouth-Hotels-Quality-Inn-Suites.h519794.Hotel-Information)

Portsmouth

7.0/10

Good

(565)

"Property in need of regular maintenance, breakfast was sub par, 4 out 10, however the bed was comfortable. Will try a different property next time I'm in town "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Don

CA $97

CA $108 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/Portsmouth-Hotels-Quality-Inn-Suites.h519794.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-30&endDate=2025-12-31&regionId=7601&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true)

## Top Wheelersburg Hotel Reviews

![Quality Inn](https://images.trvl-media.com/lodging/1000000/40000/34200/34164/4670d89c_y.jpg)

### Quality Inn

10/10 Excellent

"Happy"

[](https://expedia.ca/Portsmouth-Hotels-Quality-Inn.h34164.Hotel-Information)

![Holiday Inn Express & Suites Ironton by IHG](https://images.trvl-media.com/lodging/9000000/8710000/8702000/8701954/68a37f70_y.jpg)

### Holiday Inn Express & Suites Ironton by IHG

10/10 Excellent

"Everything was kept up and breakfast was good "

[](https://expedia.ca/Ironton-Hotels-Holiday-Inn-Express-Suites-Ironton.h8701954.Hotel-Information)

![Quality Inn](https://images.trvl-media.com/lodging/1000000/20000/14700/14647/6a921f8c_y.jpg)

### Quality Inn

10/10 Excellent

"Nice staffing room. Good breakfast. Easy on and off the expressway "

[](https://expedia.ca/Chillicothe-Hotels-Quality-Inn.h14647.Hotel-Information)

![Holiday Inn Portsmouth Downtown by IHG](https://images.trvl-media.com/lodging/1000000/30000/20500/20403/42ca14f7_y.jpg)

### Holiday Inn Portsmouth Downtown by IHG

10/10 Excellent

"Staff members were all friendly and professional!"

[](https://expedia.ca/Portsmouth-Hotels-Holiday-Inn-Portsmouth-Downtown.h20403.Hotel-Information)

![Super 8 by Wyndham Portsmouth](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/2623add7_y.jpg)

### Super 8 by Wyndham Portsmouth

10/10 Excellent

"V "

[](https://expedia.ca/Portsmouth-Hotels-Super-8-By-Wyndham-Portsmouth.h39801.Hotel-Information)

![Quality Inn](https://images.trvl-media.com/lodging/1000000/60000/56000/55986/0f828bad_y.jpg)

### Quality Inn

10/10 Excellent

"Yes"

[](https://expedia.ca/Ashland-Hotels-Quality-Inn.h55986.Hotel-Information)

![Best Western River Cities](https://images.trvl-media.com/lodging/1000000/920000/914000/913954/23f0df18_y.jpg)

### Best Western River Cities

10/10 Excellent

"Staff was nice. Scott helped us out as well as the lady that works overnights. The room was simple and clean. Breakfast was good for what it was. Stayed here last year and will stay next year for Thanksgiving and Christmas as well when we visit family. "

[](https://expedia.ca/Ashland-Hotels-Best-Western-River-Cities.h913954.Hotel-Information)

![Red Roof Inn Jackson, OH](https://images.trvl-media.com/lodging/1000000/920000/911900/911869/dc72906a_y.jpg)

### Red Roof Inn Jackson, OH

10/10 Excellent

"Staff was incredibly courteous! "

[](https://expedia.ca/Chillicothe-Hotels-Red-Roof-Inn-Jackson.h911869.Hotel-Information)

![Quality Inn & Suites Portsmouth](https://images.trvl-media.com/lodging/1000000/520000/519800/519794/ea5c8667_y.jpg)

### Quality Inn & Suites Portsmouth

10/10 Excellent

"Everything "

[](https://expedia.ca/Portsmouth-Hotels-Quality-Inn-Suites.h519794.Hotel-Information)

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