Title: Hotels by La Quinta Inn & Suites in West Main Historic District from CA $130 | Expedia.ca [West Main Historic District Travel Guide](https://expedia.ca/Louisville-West-Main-Historic-District.dx6338837)[Vacation Rentals in Louisville](https://expedia.ca/Louisville-Vacation-Rentals.d603002.Travel-Guide-VacationRentals)[Flights to Louisville](https://expedia.ca/Cheap-Flights-To-Louisville.d603002.Travel-Guide-Flights)[Things to do in Louisville](https://expedia.ca/Things-To-Do-In-Louisville.d603002.Travel-Guide-Activities)[West Main Historic District Car Rentals](https://expedia.ca/Car-Rentals-In-West-Main-Historic-District.d6338837.Car-Rental-Guide)[West Main Historic District Vacations](https://expedia.ca/West-Main-Historic-District.d6338837.Destination-Travel-Guides) ![Louisville Science Center which includes outdoor art](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297336-Louisville-Science-Center.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by La Quinta Inn & Suites in West Main Historic District from CA $130 ### Change your mind Book hotels with free cancellation ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 6 - Oct 7](https://www.expedia.ca/Hotel-Search?regionId=6338837&startDate=2025-10-06&endDate=2025-10-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 7 - Oct 8](https://www.expedia.ca/Hotel-Search?regionId=6338837&startDate=2025-10-07&endDate=2025-10-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6338837&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6338837&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top West Main Historic District La Quinta Inn & Suites Hotels ![Exterior](https://images.trvl-media.com/lodging/61000000/60540000/60539300/60539240/683aa4fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/61000000/60540000/60539300/60539240/7102f7be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/61000000/60540000/60539300/60539240/96361889.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio, 1 King Bed, Non Smoking (Efficiency with Wet Bar)](https://images.trvl-media.com/lodging/61000000/60540000/60539300/60539240/62ece1f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd Louisville 8.6/10 Excellent (875) "Everything was great staff was very helpful and breakfast was delicious " CA $121 CA $142 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Louisville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Louisville-East.h60539240.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/892900/892811/3ffcfc43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/900000/892900/892811/781b7273.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/892900/892811/23f7e496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/900000/892900/892811/5128a37e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Louisville East Jeffersontown 7.8/10 Good (992) "Nice hotel" CA $110 CA $130 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Louisville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Louisville.h892811.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-21&endDate=2025-10-22®ionId=6338837&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FWest-Main-Historic-District-Louisville-Hotels-La-Quinta-Inn-Suites.0-n6338837-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FWest-Main-Historic-District-Louisville-Hotels-La-Quinta-Inn-Suites.0-n6338837-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top West Main Historic District Hotel Reviews ![Hampton Inn Louisville Downtown](//images.trvl-media.com/lodging/1000000/10000/4900/4836/f94d4efb_y.jpg) ### Hampton Inn Louisville Downtown 10/10 Excellent "All staff were very friendly and helpful. There was an issue with the air conditioner in my room. I told the front staff and somebody was ready to fix it within 3 minutes. The hotel is also very close to many of the places I wanted to visit. " [](https://expedia.ca/Louisville-Hotels-Hampton-Inn-Louisville-Downtown.h4836.Hotel-Information) ![Cambria Hotel Louisville Downtown-Whiskey Row](//images.trvl-media.com/lodging/58000000/57960000/57959300/57959281/5084ffc5_y.jpg) ### Cambria Hotel Louisville Downtown-Whiskey Row 10/10 Excellent "Clean room. Well appointed. Close to NULU. " [](https://expedia.ca/Louisville-Hotels-CAMBRiA-Hotel-Louisville-Downtown-Whiskey-Row.h57959281.Hotel-Information) ![Towneplace Suites By Marriott Louisville Downtown](//images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/8f8322e9_y.jpg) ### Towneplace Suites By Marriott Louisville Downtown 10/10 Excellent "Great location downtown. Friendly staff. And clean rooms!" [](https://expedia.ca/Louisville-Hotels-Towneplace-Suites-By-Marriott-Louisville-Downtown.h64696084.Hotel-Information) ![Econo Lodge Downtown Louisville](//images.trvl-media.com/lodging/1000000/30000/27100/27037/1942d798_y.jpg) ### Econo Lodge Downtown Louisville 10/10 Excellent "Great place not fancy but enough " [](https://expedia.ca/Louisville-Hotels-Econo-Lodge-Downtown-Louisville.h27037.Hotel-Information) ![Hilton Garden Inn Louisville Downtown](//images.trvl-media.com/lodging/10000000/9220000/9215400/9215348/d064e9c8_y.jpg) ### Hilton Garden Inn Louisville Downtown 10/10 Excellent "Clean room " [](https://expedia.ca/Louisville-Hotels-Hilton-Garden-Inn-Louisville-Downtown.h9215348.Hotel-Information) ![Holiday Inn Louisville Downtown by IHG](//images.trvl-media.com/lodging/71000000/70110000/70102100/70102082/15afb76d_y.jpg) ### Holiday Inn Louisville Downtown by IHG 10/10 Excellent "Very friendly staff, clean and comfortable bed. My rm 416 was very very tiny. Seemed like a maintenance closet was turned into a guest room. Other than that the stay was very accommodating. " [](https://expedia.ca/Louisville-Hotels-Holiday-Inn-Louisville-Downtown.h70102082.Hotel-Information) ![21c Museum Hotel Louisville](//images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a_y.jpg) ### 21c Museum Hotel Louisville 10/10 Excellent "Great stay overall. " [](https://expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) ![The Grady](//images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/f322db40_y.jpg) ### The Grady 10/10 Excellent "Beautiful clean room. Valet attendants the young man during the day he was awesome. Room attendant came to our room to clean she was very pleasant and gave us everything we needed. Really did not see many guests maybe 4 in total so it was very peaceful and quiet." [](https://expedia.ca/Louisville-Hotels-The-Grady.h61215907.Hotel-Information) ![Holiday Inn Express & Suites Louisville Downtown by IHG](//images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/380612f2_y.jpg) ### Holiday Inn Express & Suites Louisville Downtown by IHG 10/10 Excellent "Hotel was great. Only suggestion is not serving the exact same breakfast ever day." [](https://expedia.ca/Louisville-Hotels-Holiday-Inn-Express-Suites-Louisville-Downtown.h12552757.Hotel-Information) ## Find out more about West Main Historic District ## West Main Historic District Hotels Guide Expedia.ca offers a selection of 2024 hotels in West Main Historic District. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in West Main Historic District. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the West Main Historic District neighborhood you prefer. Go ahead. 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