Title: Book the Best Wesley Chapel South LUXURY Hotels - Upscale Hotels in Wesley Chapel South, Tampa | Expedia.ca [Vacation Rentals in Tampa](https://expedia.ca/Tampa-Vacation-Rentals.d602996.Travel-Guide-VacationRentals)[Flights to Tampa](https://expedia.ca/Cheap-Flights-To-Tampa.d602996.Travel-Guide-Flights)[Things to do in Tampa](https://expedia.ca/Things-To-Do-In-Tampa.d602996.Travel-Guide-Activities)[Wesley Chapel South Car Rentals](https://expedia.ca/Car-Rentals-In-Wesley-Chapel-South.d553248635975849470.Car-Rental-Guide)[Wesley Chapel South Vacations](https://expedia.ca/Wesley-Chapel-South.d553248635975849470.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Wesley Chapel South, Tampa ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Wesley Chapel South Luxury Hotels Tonight [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635975849470&startDate=2025-10-25&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Oct 26 - Oct 27](https://www.expedia.ca/Hotel-Search?regionId=553248635975849470&startDate=2025-10-26&endDate=2025-10-27&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635975849470&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635975849470&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Wesley Chapel South Luxury Hotels ## Top Wesley Chapel South Hotel Reviews ![Comfort Suites Tampa Airport North](//images.trvl-media.com/lodging/3000000/2150000/2141800/2141751/7a73c95a_y.jpg) ### Comfort Suites Tampa Airport North 10/10 Excellent "Clean room. Breakfast was good. L" [](https://expedia.ca/Tampa-Hotels-Comfort-Suites-Tampa-Airport-North.h2141751.Hotel-Information) ![La Quinta Inn by Wyndham Tampa Near Busch Gardens](//images.trvl-media.com/lodging/1000000/70000/67700/67611/6613cf40_y.jpg) ### La Quinta Inn by Wyndham Tampa Near Busch Gardens 10/10 Excellent "Great little stay right next to bush gardens" [](https://expedia.ca/Tampa-Hotels-La-Quinta-Inn-By-Wyndham-Tampa-Near-Busch-Gardens.h67611.Hotel-Information) ![Holiday Inn Express & Suites Tampa USF Busch Gardens by IHG](//images.trvl-media.com/lodging/2000000/1990000/1988100/1988046/299a79b0_y.jpg) ### Holiday Inn Express & Suites Tampa USF Busch Gardens by IHG 10/10 Excellent "I was not able to use it due to me arriving late. Will try next time." [](https://expedia.ca/Tampa-Hotels-Holiday-Inn-Express-Suites-Tampa-USF-Busch-Gardens.h1988046.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Tampa Brandon Regency Park](//images.trvl-media.com/lodging/1000000/80000/74500/74413/50f98d3a_y.jpg) ### La Quinta Inn & Suites by Wyndham Tampa Brandon Regency Park 10/10 Excellent "Very tranquil " [](https://expedia.ca/Tampa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tampa-Brandon-Regency-Park.h74413.Hotel-Information) ![Embassy Suites by Hilton Tampa USF Near Busch Gardens](//images.trvl-media.com/lodging/1000000/80000/79300/79238/6acae8a8_y.jpg) ### Embassy Suites by Hilton Tampa USF Near Busch Gardens 10/10 Excellent "Clean room and move staff" [](https://expedia.ca/Tampa-Hotels-Embassy-Suites-By-Hilton-Tampa-USF-Near-Busch-Gardens.h79238.Hotel-Information) ![Quality Inn and Conference Center Tampa-Brandon](//images.trvl-media.com/lodging/1000000/90000/85300/85300/9ca1a030_y.jpg) ### Quality Inn and Conference Center Tampa-Brandon 10/10 Excellent "Great for our one night stay" [](https://expedia.ca/Tampa-Hotels-Clarion-Inn-And-Conference-Center-Tampa-Brandon.h85300.Hotel-Information) ![Hyatt Place Busch Gardens](//images.trvl-media.com/lodging/1000000/50000/40800/40788/7783dfc6_y.jpg) ### Hyatt Place Busch Gardens 10/10 Excellent "great facility " [](https://expedia.ca/Tampa-Hotels-Hyatt-Place-Busch-Gardens.h40788.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Tampa Central](//images.trvl-media.com/lodging/2000000/1870000/1867000/1866902/6335087e_y.jpg) ### La Quinta Inn & Suites by Wyndham Tampa Central 10/10 Excellent "Excellent stay. Great breakfast options. " [](https://expedia.ca/Tampa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tampa-Central.h1866902.Hotel-Information) ![Sleep Inn near Busch Gardens/USF](//images.trvl-media.com/lodging/1000000/90000/85100/85025/ab979cd6_y.jpg) ### Sleep Inn near Busch Gardens/USF 10/10 Excellent "Very clean" [](https://expedia.ca/Tampa-Hotels-Sleep-Inn-Near-Busch-GardensUSF.h85025.Hotel-Information) ## Frequently asked questions ### Are you searching for the perfect hotel for your luxury trip to Wesley Chapel South? > Use Expedia and let us help you arrange a flight to Tampa Intl. Airport (TPA) airport or Tampa, FL (TPF-Peter O. Knight) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a vacation, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Wesley Chapel South has to offer. Wesley Chapel South has some interesting things to see and do including Saddlebrook Golf Course and Wesley Chapel District Park, so you might want to take in the local sights during your visit. ### What's there to see and do in Wesley Chapel South? > Enjoy all that Wesley Chapel South has to offer and visit Saddlebrook Golf Course, Wesley Chapel District Park, and Busch Gardens Tampa Bay. 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