Title: Book the Best Wesley Chapel South LUXURY Hotels - Upscale Hotels in Wesley Chapel South, Tampa | Expedia.ca [Vacation Rentals in Tampa](https://expedia.ca/Tampa-Vacation-Rentals.d602996.Travel-Guide-VacationRentals)[Flights to Tampa](https://expedia.ca/Cheap-Flights-To-Tampa.d602996.Travel-Guide-Flights)[Things to do in Tampa](https://expedia.ca/Things-To-Do-In-Tampa.d602996.Travel-Guide-Activities)[Wesley Chapel South Car Rentals](https://expedia.ca/Car-Rentals-In-Wesley-Chapel-South.d553248635975849470.Car-Rental-Guide)[Wesley Chapel South Vacations](https://expedia.ca/Wesley-Chapel-South.d553248635975849470.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Wesley Chapel South, Tampa ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Wesley Chapel South Luxury Hotels Tonight [Oct 9 - Oct 10](https://www.expedia.ca/Hotel-Search?regionId=553248635975849470&startDate=2025-10-09&endDate=2025-10-10&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 10 - Oct 11](https://www.expedia.ca/Hotel-Search?regionId=553248635975849470&startDate=2025-10-10&endDate=2025-10-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635975849470&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635975849470&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Wesley Chapel South Luxury Hotels ## Top Wesley Chapel South Hotel Reviews ![Comfort Suites Tampa Airport North](//images.trvl-media.com/lodging/3000000/2150000/2141800/2141751/7a73c95a_y.jpg) ### Comfort Suites Tampa Airport North 10/10 Excellent "Clean room friendly staff and wonderful breakfast options! Great stay for your budget!" [](https://expedia.ca/Tampa-Hotels-Comfort-Suites-Tampa-Airport-North.h2141751.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Tampa Brandon Regency Park](//images.trvl-media.com/lodging/1000000/80000/74500/74413/50f98d3a_y.jpg) ### La Quinta Inn & Suites by Wyndham Tampa Brandon Regency Park 10/10 Excellent "Very close to all the restaurants and stores only 3 minutes AMAZING " [](https://expedia.ca/Tampa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tampa-Brandon-Regency-Park.h74413.Hotel-Information) ![Clarion Pointe Tampa-Brandon Near Fairgrounds and Casino](//images.trvl-media.com/lodging/1000000/30000/28500/28404/26d0c0cb_y.jpg) ### Clarion Pointe Tampa-Brandon Near Fairgrounds and Casino 10/10 Excellent "Good stay. This is the hotel I always stay at in Tampa." [](https://expedia.ca/Tampa-Hotels-Quality-Inn-Suites-Tampa-Brandon-Near-Casino.h28404.Hotel-Information) ![Ramada by Wyndham Temple Terrace/Tampa North](//images.trvl-media.com/lodging/1000000/30000/26300/26259/e67e91f1_y.jpg) ### Ramada by Wyndham Temple Terrace/Tampa North 10/10 Excellent "Decent and close to my job. I dint realize it was an outside hotel— my only dislike. Other than that, I’m pretty decent. Breakfast was great!" [](https://expedia.ca/Tampa-Hotels-Ramada-By-Wyndham-Temple-TerraceTampa-North.h26259.Hotel-Information) ![Holiday Inn Tampa North by IHG](//images.trvl-media.com/lodging/1000000/120000/117800/117781/ec69f385_y.jpg) ### Holiday Inn Tampa North by IHG 10/10 Excellent "Need more parking ." [](https://expedia.ca/Tampa-Hotels-Holiday-Inn-Tampa-North.h117781.Hotel-Information) ![La Quinta Inn & Suites by Wyndham USF (Near Busch Gardens)](//images.trvl-media.com/lodging/1000000/90000/82300/82254/9f877dbe_y.jpg) ### La Quinta Inn & Suites by Wyndham USF (Near Busch Gardens) 10/10 Excellent "Yuengling brewery, Busch gardens, botanical garden, USF, Moffitt cancer center within a few minutes drive. Lots of restaurants & easy access to Tampa. Hotel undergoing upgrades, very comfortable." [](https://expedia.ca/Tampa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-USF.h82254.Hotel-Information) ![Hyatt Place Busch Gardens](//images.trvl-media.com/lodging/1000000/50000/40800/40788/7783dfc6_y.jpg) ### Hyatt Place Busch Gardens 10/10 Excellent "I had surgery at Moffit and they were very understanding and very helpful Only comment I would make is the be bathroom needs to be bigger " [](https://expedia.ca/Tampa-Hotels-Hyatt-Place-Busch-Gardens.h40788.Hotel-Information) ![Embassy Suites by Hilton Tampa USF Near Busch Gardens](//images.trvl-media.com/lodging/1000000/80000/79300/79238/6acae8a8_y.jpg) ### Embassy Suites by Hilton Tampa USF Near Busch Gardens 10/10 Excellent "Anna at the front desk was awesome. Didn’t care much for how to pay for parking. Crazy to pay for parking when you booked a room. Should be included already." [](https://expedia.ca/Tampa-Hotels-Embassy-Suites-By-Hilton-Tampa-USF-Near-Busch-Gardens.h79238.Hotel-Information) ![Sleep Inn near Busch Gardens/USF](//images.trvl-media.com/lodging/1000000/90000/85100/85025/6b50d070_y.jpg) ### Sleep Inn near Busch Gardens/USF 10/10 Excellent "Excellent " [](https://expedia.ca/Tampa-Hotels-Sleep-Inn-Near-Busch-GardensUSF.h85025.Hotel-Information) ## Frequently asked questions ### Are you searching for the perfect hotel for your luxury trip to Wesley Chapel South? > Use Expedia and let us help you arrange a flight to Tampa Intl. Airport (TPA) airport or Tampa, FL (TPF-Peter O. Knight) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a vacation, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Wesley Chapel South has to offer. Wesley Chapel South has some interesting things to see and do including Saddlebrook Golf Course and Wesley Chapel District Park, so you might want to take in the local sights during your visit. ### What's there to see and do in Wesley Chapel South? > Enjoy all that Wesley Chapel South has to offer and visit Saddlebrook Golf Course, Wesley Chapel District Park, and Busch Gardens Tampa Bay. 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