Title: Book the Best Waynesville LUXURY Hotels - Upscale Hotels in Waynesville, MO | Expedia.ca [Hotels in Waynesville](https://expedia.ca/Waynesville-Hotels.d55214.Travel-Guide-Hotels)[Vacation Rentals in Waynesville](https://expedia.ca/Waynesville-Vacation-Rentals.d55214.Travel-Guide-VacationRentals)[Flights to Waynesville](https://expedia.ca/Cheap-Flights-To-Waynesville.d55214.Travel-Guide-Flights)[Waynesville Car Rentals](https://expedia.ca/Car-Rentals-In-Waynesville.d55214.Car-Rental-Guide)[Waynesville Vacation Packages](https://expedia.ca/Waynesville.d55214.Destination-Travel-Guides) ![Big Piney Railroad Bridge](https://images.trvl-media.com/place/55214/0a67d849-07f5-4f1e-9b57-a1a6287ab34d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/55214/0a67d849-07f5-4f1e-9b57-a1a6287ab34d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Waynesville Luxury Hotels Tonight [Feb 4 - Feb 5](https://www.expedia.ca/Hotel-Search?regionId=55214&startDate=2026-02-04&endDate=2026-02-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=55214&startDate=2026-02-05&endDate=2026-02-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=55214&startDate=2026-02-06&endDate=2026-02-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=55214&startDate=2026-02-13&endDate=2026-02-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Find out more about Waynesville ### Waynesvilleand its attractions for luxury travelers Nestled in the scenic Ozarks, Waynesville, Missouri, offers a unique blend of natural beauty and rich history that caters to luxury travellers. One of the must-visit attractions is the Mark Twain National Forest, where you can indulge in exclusive guided tours of its picturesque trails, perfect for both hiking and horseback riding while soaking in the stunning views. History enthusiasts will appreciate a visit to the nearby Old Stagecoach Stop Museum, showcasing the town's fascinating past with engaging exhibits that highlight its role in early American transportation. For a taste of local culture, the Waynesville-St. Robert Chamber of Commerce hosts seasonal events featuring artisanal crafts and gourmet food vendors, ensuring a delightful experience that showcases the region’s finest. Golf aficionados can tee off at the picturesque Oak Meadow Country Club, where the manicured greens provide a serene backdrop for a relaxing day on the course. After a day of exploration, unwinding in one of Waynesville's upscale hotels, particularly those near the town centre, allows for convenient access to local dining and shopping while enjoying amenities like spa treatments or fine dining options. With attentive service and premium rooms, these hotels ensure that every aspect of your stay is tailored to perfection. ### Find the best luxury hotels and resorts in Waynesville For those seeking a taste of luxury in Waynesville, Missouri, these exquisite hotel options promise an indulgent experience. Each hotel boasts exceptional amenities tailored for a refined stay. [**Lafayette Grand Manor**](https://www.expedia.ca/Rolla-Hotels-Lafayette-Manor-BB.h11496998.Hotel-Information) - **Why it's great for a luxury retreat:** The Lafayette Grand Manor stands as a beacon of luxury, perfect for travelers looking for an extraordinary getaway. With a remarkable review rating of 9.8, this elegant retreat features sumptuous amenities such as deep soaking bathtubs and premium bedding, ensuring guests experience the utmost comfort and relaxation. The warm ambiance is enhanced by the presence of fireplaces, creating a cosy yet sophisticated setting for an indulgent escape. - **Other amenities:** Guests can enjoy a range of additional features including a shared refrigerator and microwave, ideal for in-room convenience. The outdoor pool invites relaxation during warmer months, while the terrace and gardens offer serene spots for unwinding. With on-site housekeeping and flexible check-in and check-out times, guests are assured a seamless stay. Fitness facilities are available nearby for those looking to maintain their exercise routine, ensuring a blend of leisure and wellness during their luxurious retreat. - **Nearby attractions:** Mark Twain National Forest - 0 km, Waynesville Splash Park - 7.9 km, Roubidoux Park - 7.9 km ## Top Waynesville Hotel Reviews ## Frequently asked questions ### Which area of Waynesville is best to stay in for luxury hotels? > This area is the primary commercial hub of Waynesville, offering the newest and most upscale accommodation options. You'll find a selection of hotels that cater to a more discerning traveller, often featuring amenities like larger rooms, modern decor, and high-end fitness equipment. The hotels here are conveniently located for those visiting Fort Leonard Wood, as they are just a short drive from the main entrance. > > > Couples looking for a comfortable and convenient stay will appreciate the hotels in this part of Waynesville. Many establishments offer excellent dining options on-site or within easy walking distance, making it simple to enjoy a nice evening without venturing far. ### How much does a luxury hotel in Waynesville cost? ### What luxury activities and experiences are there in Waynesville? > For a refined dining experience, consider places that focus on locally sourced ingredients and offer a sophisticated menu. You might find establishments that specialise in pairing meals with fine wines or craft beers, providing a more upscale culinary journey than typical local eateries. Look for restaurants that highlight regional American cuisine with a modern twist. > > > For a unique and memorable experience, you could arrange a private guided tour of the Mark Twain National Forest. This could involve a bespoke itinerary focusing on areas of particular natural beauty, perhaps with a gourmet picnic lunch prepared by a local chef. Some local outfitters may offer bespoke fly-fishing excursions with expert guides, providing all the necessary high-end equipment for a premium outdoor adventure. > > > Finally, for those who appreciate fine craftsmanship, exploring local art galleries or artisan workshops can be a luxurious way to spend an afternoon. ### How can I save on a luxury hotel in Waynesville with Expedia? ### Is it cheaper to book a luxury Waynesville hotel and flights as a package? ### Can I cancel my luxury hotel reservation on Expedia? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [3 Star Hotels in Dixon ](https://www.expedia.ca/3Star-Dixon-Hotels.s30-0-d553248634983541009.Travel-Guide-Filter-Hotels) - [Aparthotels in Buckhorn ](https://www.expedia.ca/Buckhorn-Apart-Hotels.d553248635975868238-aaApartHotels.Travel-Guide-Accommodation) - [Guest Houses in Buckhorn ](https://www.expedia.ca/Buckhorn-Guest-Houses.d553248635975868238-aaGuestHouses.Travel-Guide-Accommodation) - 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