Title: Book the Best Vine SPA Resorts from CA $216 - Spa Hotels in Vine, Kalamazoo | Expedia.ca [Vacation Rentals in Kalamazoo](https://expedia.ca/Kalamazoo-Vacation-Rentals.d486.Travel-Guide-VacationRentals)[Flights to Kalamazoo](https://expedia.ca/Cheap-Flights-To-Kalamazoo.d486.Travel-Guide-Flights)[Things to do in Kalamazoo](https://expedia.ca/Things-To-Do-In-Kalamazoo.d486.Travel-Guide-Activities)[Vine Car Rentals](https://expedia.ca/Car-Rentals-In-Vine.d553248635976469494.Car-Rental-Guide)[Vine Vacations](https://expedia.ca/Vine.d553248635976469494.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/7ff9a7e4e40127da17f67144e1d18bbe.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Patrick Laughlin  # Find Spa Hotels in Vine, Kalamazoo from CA $216 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Vine Spa Hotels Tonight [Oct 22 - Oct 23](https://www.expedia.ca/Hotel-Search?regionId=553248635976469494&startDate=2025-10-22&endDate=2025-10-23&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=553248635976469494&startDate=2025-10-23&endDate=2025-10-24&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976469494&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976469494&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Vine Spa Hotels ![Deluxe Room, Garden View](https://images.trvl-media.com/lodging/113000000/112310000/112309100/112309022/1e4a6b37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/113000000/112310000/112309100/112309022/15c7993b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, Garden View | Living area](https://images.trvl-media.com/lodging/113000000/112310000/112309100/112309022/4d41881e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112310000/112309100/112309022/1f2594c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Upjohn House Inn Kalamazoo Central Business District 7.0/10 Good (19) "No service nobody around ,,soiled sheets, and pillowcases. We had to request sheets. My wife had to make the her own bed, put the pillow sheets on nothing was accessible for housekeeping because there was nobody around. No way to turn down the AC. It ran all night very very cold. Definitely not worth $215 a night and that was discounted wouldn’t pay more than 60 or 70 bucks to stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew CA $194 CA $216 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Kalamazoo-Hotels-Upjohn-House-Inn.h112309022.Hotel-Information) ![Couples treatment rooms, steam room, body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/10000/2300/2221/c9faa5a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/10000/2300/2221/b1ba97e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking, Kitchen (1 Bedroom)](https://images.trvl-media.com/lodging/1000000/10000/2300/2221/a7503934.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2300/2221/cf615ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Plaza Hotel at Kalamazoo Center Kalamazoo Central Business District 9.0/10 Wonderful (1001) "A very good stay. Hotel is great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melvyn CA $320 CA $368 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Kalamazoo-Hotels-Radisson-Plaza-Hotel-At-Kalamazoo-Center.h2221.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-06&endDate=2025-11-07®ionId=553248635976469494&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Vine ### Top Vine attractions for a relaxing vacation In the Vine neighbourhood, travellers seeking a rejuvenating spa experience will find a range of luxury hotels that blend comfort with unique local charm. Begin your stay with a visit to the stunning Vine Street Park, where serene walking paths and lush greenery provide the perfect backdrop for relaxation or a leisurely picnic. Just a stone's throw away, indulge in a therapeutic session at the renowned Vine Spa, offering an array of treatments that utilise local ingredients to refresh both body and mind. For a taste of local culture, the nearby Wine & Art Festival showcases the best of regional wines and artistic talent, allowing you to sip and savour while exploring the vibrant community. After a day of exploration, unwind at the hotel’s exclusive rooftop pool, where panoramic views of the city and sunset cocktails create an unforgettable evening. Each hotel in Vine prides itself on exceptional service, ensuring that after your daily adventures, you return to luxurious rooms equipped with modern amenities and tranquil spa facilities, making every moment of your stay feel indulgent. ## Top Vine Hotel Reviews ![Comfort Inn Wings Stadium](//images.trvl-media.com/lodging/1000000/20000/10500/10470/175936aa_y.jpg) ### Comfort Inn Wings Stadium 10/10 Excellent "We really enjoy our self . The breakfasts were really nice and good friday. I also had apples and oranges." [](https://expedia.ca/Kalamazoo-Hotels-Comfort-Inn-Wings-Stadium.h10470.Hotel-Information) ![Courtyard Kalamazoo Portage](//images.trvl-media.com/lodging/7000000/6450000/6447900/6447847/3274f64e_y.jpg) ### Courtyard Kalamazoo Portage 10/10 Excellent "Clean room, friendly staff " [](https://expedia.ca/Kalamazoo-Hotels-Courtyard-Kalamazoo-Portage.h6447847.Hotel-Information) ![Best Western Plus Kalamazoo Suites](//images.trvl-media.com/lodging/1000000/550000/543800/543732/dcb5315d_y.jpg) ### Best Western Plus Kalamazoo Suites 10/10 Excellent "Nice place to stay! Would stay again!" [](https://expedia.ca/Kalamazoo-Hotels-Best-Western-Plus-Kalamazoo-Suites.h543732.Hotel-Information) ![Radisson Plaza Hotel at Kalamazoo Center](//images.trvl-media.com/lodging/1000000/10000/2300/2221/b1ba97e6_y.jpg) ### Radisson Plaza Hotel at Kalamazoo Center 10/10 Excellent "Enjoyed the entire facility, restaurant, pub, relaxation. Wonderful well cared for all aspects. " [](https://expedia.ca/Kalamazoo-Hotels-Radisson-Plaza-Hotel-At-Kalamazoo-Center.h2221.Hotel-Information) ![Delta Hotels by Marriott Kalamazoo Conference Center](//images.trvl-media.com/lodging/1000000/20000/17000/16960/4fceec82_y.jpg) ### Delta Hotels by Marriott Kalamazoo Conference Center 10/10 Excellent "Everything was great. Cool comfortable room, very accommodating." [](https://expedia.ca/Kalamazoo-Hotels-Delta-Hotels-By-Marriott-Kalamazoo-Conference-Center.h16960.Hotel-Information) ## Frequently asked questions ### Looking to vacation at a spa hotel in Vine? > Treat yourself to some time in a luxurious spa hotel and you won't regret it. Spa hotels are a great way to take a break from your daily routine and add a layer of luxury to your vacation. ### What's there to see and do in Vine? > Experience all that Vine has to offer when you visit Waldo Stadium, Kalamazoo Institute of Arts, and Kalamazoo State Theatre. If you have some spare time during your trip, you might want to check out Kalamazoo Valley Museum and James W. Miller Auditorium. ### What is a Vine spa hotel? > Spa hotels in Vine have full on-site spas and offer services including massages and a range of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. 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