Title: Hotels by Highgate Independent in Uptown - Upper Duval from CA $252 | Expedia.ca [Uptown - Upper Duval Travel Guide](https://expedia.ca/Key-West-Uptown-Upper-Duval.dx553248635976473524)[Flights to Key West](https://expedia.ca/Cheap-Flights-To-Key-West.d1187.Travel-Guide-Flights)[Things to do in Key West](https://expedia.ca/Things-To-Do-In-Key-West.d1187.Travel-Guide-Activities)[Uptown - Upper Duval Car Rentals](https://expedia.ca/Car-Rentals-In-Uptown-Upper-Duval.d553248635976473524.Car-Rental-Guide)[Uptown - Upper Duval Vacations](https://expedia.ca/Uptown-Upper-Duval.d553248635976473524.Destination-Travel-Guides) ![Key West Butterfly and Nature Conservatory showing flowers, animals and zoo animals](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63942-Key-West-Butterfly-And-Nature-Conservatory.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Highgate Independent in Uptown - Upper Duval from CA $252 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 10 - Oct 11](https://www.expedia.ca/Hotel-Search?regionId=553248635976473524&startDate=2025-10-10&endDate=2025-10-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 11 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635976473524&startDate=2025-10-11&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635976473524&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976473524&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Uptown - Upper Duval Highgate Independent Hotels ![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/026f10af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/69828d6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/4eda9d17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, beach views ](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/8f43a3d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Southernmost Beach Resort and Guesthouses Old Town Key West 8.6/10 Excellent (2778) "The property and staff was great" CA $238 CA $362 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Key-West-Hotels-Southernmost-Beach-Resort.h863329.Hotel-Information) ![2 outdoor pools, open 7:00 AM to 11:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/13000000/12600000/12599300/12599231/cb0a4c1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/13000000/12600000/12599300/12599231/5792173a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12600000/12599300/12599231/44728c35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12600000/12599300/12599231/dcdeb665.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blue Flamingo Resort Key West New Town 8.0/10 Very good (1610) "Nice area big pools. " CA $154 CA $252 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Key-West-Hotels-24-North-Hotel-Key-West-Newly-Renovated.h12599231.Hotel-Information) ![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/10000000/9150000/9148400/9148379/15d13ee3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9150000/9148400/9148379/a156943e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/10000000/9150000/9148400/9148379/e32c81ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Harbor View King with Balcony | View from property](https://images.trvl-media.com/lodging/10000000/9150000/9148400/9148379/7692f964.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Marker Key West Harbor Resort Key West Historic District 9.2/10 Wonderful (1011) "Great location and accommodations - just perfect !" CA $236 CA $350 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Key-West-Hotels-The-Marker-Key-West-Harbor-Resort.h9148379.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2800000/2796000/2795938/47e1af5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/3000000/2800000/2796000/2795938/43039b04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Newly Renovated - Avalon Two Queen](https://images.trvl-media.com/lodging/3000000/2800000/2796000/2795938/15ecf16f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2800000/2796000/2795938/a9f1e2d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Duval Gardens at Southernmost Beach Resort – Adults Only Old Town Key West 9.2/10 Wonderful (922) "Hotel was great and Kasey the activities direct was so fun and helpful" [](https://www.expedia.ca/Key-West-Hotels-Avalon-Bed-Breakfast.h2795938.Hotel-Information) ![Bicycling](https://images.trvl-media.com/lodging/26000000/25010000/25004500/25004428/36898429.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Boating](https://images.trvl-media.com/lodging/26000000/25010000/25004500/25004428/3082c224.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/26000000/25010000/25004500/25004428/f7f3f803.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed](https://images.trvl-media.com/lodging/26000000/25010000/25004500/25004428/32365776.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Guesthouses at Southernmost Beach Resort Old Town Key West 9.4/10 Exceptional (311) "We had a fabulous stay at the Duval Gardens, now part of the Southernmost Beach Resort Hotel (guesthouses) Great location and the breakfast in the morning on the porch was lovely. The beds were a little firm for our liking but other then that the stay was perfect. Kimberly took great care of us and made the stay even better! " [](https://www.expedia.ca/Key-West-Hotels-The-Guesthouses-At-Southernmost-Beach-Resort.h25004428.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25®ionId=553248635976473524&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUptown-Upper-Duval-Key-West-Hotels-Highgate-Independent.0-n553248635976473524-0--bHighgateIndependent.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUptown-Upper-Duval-Key-West-Hotels-Highgate-Independent.0-n553248635976473524-0--bHighgateIndependent.Travel-Guide-Filter-Hotels) ## Top Uptown - Upper Duval Hotel Reviews ![Parrot Key Hotel & Villas](//images.trvl-media.com/lodging/1000000/30000/24700/24615/b83a5985_y.jpg) ### Parrot Key Hotel & Villas 10/10 Excellent "Impeccable service" [](https://expedia.ca/Key-West-Hotels-Parrot-Key-Hotel-Villas.h24615.Hotel-Information) ![Hilton Garden Inn Key West / The Keys Collection](//images.trvl-media.com/lodging/1000000/10000/1400/1376/5c83029c_y.jpg) ### Hilton Garden Inn Key West / The Keys Collection 10/10 Excellent "Clean grounds, clean room, loved the shuttle service to town and back to hotel, access to all 3 properties and pools which were wonderful and staff professional and courteous." [](https://expedia.ca/Key-West-Hotels-Hilton-Garden-Inn-Key-West.h1376.Hotel-Information) ![Kona Kai Oasis](//images.trvl-media.com/lodging/2000000/1640000/1635900/1635855/0be5a7c1_y.jpg) ### Kona Kai Oasis 10/10 Excellent "Was not aware there was not going to be a front desk. Staff had to help me" [](https://expedia.ca/Key-West-Hotels-An-Island-Oasis.h1635855.Hotel-Information) ![Santa Maria Suites](//images.trvl-media.com/lodging/1000000/920000/911000/910922/8aacf584_y.jpg) ### Santa Maria Suites 10/10 Excellent "Staff are fantastic. The grounds are beautiful. Rooms are clean. Cant ask for more" [](https://expedia.ca/Key-West-Hotels-Santa-Maria-Suites.h910922.Hotel-Information) ![Douglas House](//images.trvl-media.com/lodging/111000000/110490000/110488200/110488130/a2bf0992_y.jpg) ### Douglas House 10/10 Excellent "Great location " [](https://expedia.ca/Key-West-Hotels-Douglas-House.h110488130.Hotel-Information) ![Hyatt Centric Key West Resort and Spa](//images.trvl-media.com/lodging/1000000/10000/1000/901/0b72a249_y.jpg) ### Hyatt Centric Key West Resort and Spa 10/10 Excellent "Beautiful hotel rooms are awesome " [](https://expedia.ca/Key-West-Hotels-Hyatt-Centric-Key-West-Resort-And-Spa.h901.Hotel-Information) ![Oceans Edge Key West Resort, Hotel & Marina](//images.trvl-media.com/lodging/17000000/16210000/16203000/16202992/3a4457a0_y.jpg) ### Oceans Edge Key West Resort, Hotel & Marina 10/10 Excellent "Overall just a good placecto saty whike yiur there" [](https://expedia.ca/Key-West-Hotels-Oceans-Edge-Key-West-Resort.h16202992.Hotel-Information) ![Southernmost House](//images.trvl-media.com/lodging/4000000/3840000/3830600/3830519/9dea706f_y.jpg) ### Southernmost House 10/10 Excellent "The Southernmost House, was beautiful, and the staff was wonderful. The complimentary breakfast was very good and had many options to choose from. They always had cold bottles of water for all who stayed there, and the outside porches were just wonderful to relax on at all times of the day" [](https://expedia.ca/Key-West-Hotels-The-Southernmost-House-Hotel.h3830519.Hotel-Information) ![The Reach Key West, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/460000/457900/457821/888fac6b_y.jpg) ### The Reach Key West, Curio Collection by Hilton 10/10 Excellent "The receptionists were very friendly and helpful and 4 Marlins was food exquisite !" [](https://expedia.ca/Key-West-Hotels-The-Reach-Key-West.h457821.Hotel-Information) ## Find out more about Uptown - Upper Duval ## Uptown - Upper Duval Hotels Guide Expedia.ca offers a selection of 2799 hotels in Uptown - Upper Duval. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Uptown - Upper Duval. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Uptown - Upper Duval neighborhood you prefer. Go ahead. Enter your travel dates to view the best offers on hotel rooms in Uptown - Upper Duval, Key West now! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Other - More ways to book - [Hilton Hotels in Big Pine Key](https://www.expedia.ca/Big-Pine-Key-Hotels-Hilton-Hotels.0-0-d7195--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Downtown Key West](https://www.expedia.ca/Downtown-Key-West-Key-West-Hotels-Adults-Only-Resorts.0-n553248635976470405-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Downtown Key West](https://www.expedia.ca/Downtown-Key-West-Key-West-Hotels-Beach-Hotel.0-n553248635976470405-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Downtown Key West](https://www.expedia.ca/Downtown-Key-West-Key-West-Hotels-Boutique-Hotel.0-n553248635976470405-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in Downtown Key West](https://www.expedia.ca/Downtown-Key-West-Key-West-Hotels-Casino-Hotel.0-n553248635976470405-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - 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