Title: Book the Best Uptown Greenville LUXURY Hotels - Upscale Hotels in Uptown Greenville, Greenville | Expedia.ca

  

[Uptown Greenville Travel Guide](https://expedia.ca/Greenville-Uptown-Greenville.dx908648619872518144)[Vacation Rentals in Greenville](https://expedia.ca/Greenville-Vacation-Rentals.d2779.Travel-Guide-VacationRentals)[Flights to Greenville](https://expedia.ca/Cheap-Flights-To-Greenville.d2779.Travel-Guide-Flights)[Uptown Greenville Car Rentals](https://expedia.ca/Car-Rentals-In-Uptown-Greenville.d908648619872518144.Car-Rental-Guide)[Uptown Greenville Vacations](https://expedia.ca/Uptown-Greenville.d908648619872518144.Destination-Travel-Guides)

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# Find Luxury Hotels in Uptown Greenville, Greenville

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## Check availability on Uptown Greenville Luxury Hotels

Tonight

[Oct 19 - Oct 20](https://www.expedia.ca/Hotel-Search?regionId=908648619872518144&startDate=2025-10-19&endDate=2025-10-20&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Oct 20 - Oct 21](https://www.expedia.ca/Hotel-Search?regionId=908648619872518144&startDate=2025-10-20&endDate=2025-10-21&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=908648619872518144&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

In two weeks

[Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=908648619872518144&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Top Uptown Greenville Luxury Hotels

## Top Uptown Greenville Hotel Reviews

![Affordable Suites Greenville](//images.trvl-media.com/lodging/3000000/2690000/2682700/2682635/41b082ee_y.jpg)

### Affordable Suites Greenville

10/10 Excellent

"Very comfortable bed; very nice pillows; bathroom has all the showering essentials: shampoo, soap, conditioner, etc. Extra paper towels and toilet paper provided. Just remember to bring a charger block to charge your electronics."

[](https://expedia.ca/Greenville-Hotels-Affordable-Suites.h2682635.Hotel-Information)

![Microtel Inn & Suites by Wyndham Greenville/University Medic](//images.trvl-media.com/lodging/3000000/2010000/2009600/2009531/2e252281_y.jpg)

### Microtel Inn & Suites by Wyndham Greenville/University Medic

10/10 Excellent

"I always book here! "

[](https://expedia.ca/Greenville-Hotels-Microtel-Inn-Suites-By-Wyndham-GreenvilleUniversity-Medic.h2009531.Hotel-Information)

![Quality Inn Greenville near University](//images.trvl-media.com/lodging/1000000/20000/13600/13542/d6fc4788_y.jpg)

### Quality Inn Greenville near University

10/10 Excellent

"I expected this to be "

[](https://expedia.ca/Greenville-Hotels-Quality-Inn-Greenville-Near-University.h13542.Hotel-Information)

![Holiday Inn Greenville by IHG](//images.trvl-media.com/lodging/1000000/20000/12900/12870/8d14df71_y.jpg)

### Holiday Inn Greenville by IHG

10/10 Excellent

"Property was nice and well kept. Breakfast was good though not a lot of choice."

[](https://expedia.ca/Greenville-Hotels-Holiday-Inn-Greenville.h12870.Hotel-Information)

![Baymont by Wyndham Greenville](//images.trvl-media.com/lodging/1000000/20000/10700/10685/b467b520_y.jpg)

### Baymont by Wyndham Greenville

10/10 Excellent

"The property was alright and the amenities were fine. Close to where I needed to go."

[](https://expedia.ca/Greenville-Hotels-Baymont-By-Wyndham-Greenville.h10685.Hotel-Information)

## Frequently asked questions

### Are you looking for a luxury hotel for your stay in Uptown Greenville?

> Expedia can help you arrange a flight to Greenville, NC (PGV-Pitt-Greenville) airport, and then you can select from various places to stay that will deliver the luxury you'd like to find. Amenities are important when you plan a trip, so we make it easy to get what you want to make your stay relaxing and comfortable. If you want an upscale hotel with fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that Uptown Greenville offers. Uptown Greenville has some interesting things to see and do including Town Common and Greenville Museum of Art, so you might want to take in the local sights during your visit.

### What's there to see and do in Uptown Greenville?

> Experience Uptown Greenville and visit Town Common, Williams Arena at Minges Coliseum, and Dowdy–Ficklen Stadium. If you have some spare time during your trip, you might want to check out Clark-LeClair Stadium and Bradford Creek Golf Club.

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