Upstate South Carolina Vacation Rentals

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Check prices for these dates

Next weekend
Aug 22 - Aug 24
In two weeks
Aug 29 - Aug 31
In one month
Sep 12 - Sep 14
In two months
Oct 10 - Oct 12

Browse Select Upstate South Carolina Vacation Homes

Keowee Key Townhome - Pet Friendly, View of Golf Course plus Amenities
Outdoor dining

Keowee Key Townhome - Pet Friendly, View of Golf Course plus Amenities

9.8 out of 10, Exceptional, (72)
"Everything was easy and as expected. The owner is very responsive "
Keowee Key Townhome - Pet Friendly, View of Golf Course plus Amenities
Grand Greenville Estate ~ walk to Furman & Swamp Rabbit Trail!
Fridge, microwave, oven, stovetop

Grand Greenville Estate ~ walk to Furman & Swamp Rabbit Trail!

10.0 out of 10, Exceptional, (17)
"My family stayed here while attending a wedding. It was a perfect place for us. It was close to downtown and lots of restaurants."
The price is CA $236
CA $625 total
includes taxes & fees
Aug 20 - Aug 21
Grand Greenville Estate ~ walk to Furman & Swamp Rabbit Trail!
New Construction Townhome Less Than 1 Mile From The Heart Of Downtown Greenville
Fridge, microwave, oven, stovetop

New Construction Townhome Less Than 1 Mile From The Heart Of Downtown Greenville

9.6 out of 10, Exceptional, (60)
"This property was clean and everyone had their own space. The shopping and dining were very close so it was easy to get downtown Overall I would recommend this vacation home a 10"
New Construction Townhome Less Than 1 Mile From The Heart Of Downtown Greenville
Lake Jocassee retreat on two acres!! New hot tub, Devil’s Fork State Park
Terrace/patio

Lake Jocassee retreat on two acres!! New hot tub, Devil’s Fork State Park

10.0 out of 10, Exceptional, (14)
"Very clean, beautiful and serene views, great location, extremely accommodating hosts, comfy beds, perfect getaway to the beautiful Lake Jocassee, this was a trip for the books"
Lake Jocassee retreat on two acres!! New hot tub, Devil’s Fork State Park
Luxury 4BR/4BA Lake Keowee Retreat- Mountain Cabin Vibes + Private Dock
Exterior

Luxury 4BR/4BA Lake Keowee Retreat- Mountain Cabin Vibes + Private Dock

10.0 out of 10, Exceptional, (5)
Luxury 4BR/4BA Lake Keowee Retreat- Mountain Cabin Vibes + Private Dock
2-bedroom vacation home just 7 minutes from Haywood Mall - Cleaning Fee Included
Fridge, microwave, oven, stovetop

2-bedroom vacation home just 7 minutes from Haywood Mall - Cleaning Fee Included

10.0 out of 10, Exceptional, (55)
"Cozy small home. Perfect for a few nights stay. Host left lots of yummy snacks and even a gift card! Highly recommend for the price. "
2-bedroom vacation home just 7 minutes from Haywood Mall - Cleaning Fee Included
New! Boutique Tiny Home on the Saluda River
Outdoor dining

New! Boutique Tiny Home on the Saluda River

9.8 out of 10, Exceptional, (72)
"This was a wonderful place to stay at over the weekend. "
New! Boutique Tiny Home on the Saluda River
Relaxing Multi-family waterfront home with private dock on Lake Hartwell!
Exterior

Relaxing Multi-family waterfront home with private dock on Lake Hartwell!

10.0 out of 10, Exceptional, (106)
"Great house with everything you could possibly need!"
Relaxing Multi-family waterfront home with private dock on Lake Hartwell!
Lake Hartwell Waterfront w/Dock, Waterfall, Gameroom, Firepit, Pets, Fenced Yard
Property grounds

Lake Hartwell Waterfront w/Dock, Waterfall, Gameroom, Firepit, Pets, Fenced Yard

10.0 out of 10, Exceptional, (6)
Lake Hartwell Waterfront w/Dock, Waterfall, Gameroom, Firepit, Pets, Fenced Yard
Secluded cabin surrounded by mountains, waterfalls, wildlife, and 50,000 acres
Terrace/patio

Secluded cabin surrounded by mountains, waterfalls, wildlife, and 50,000 acres

10.0 out of 10, Exceptional, (50)
"Very secluded relaxing getaway. Tons to do nearby and plenty to do right there on the property. Wonderful place for families ❤️"
Secluded cabin surrounded by mountains, waterfalls, wildlife, and 50,000 acres
Spacious house for groups-3 mi from CU! Across from Patrick Square!
Fridge, microwave, oven, stovetop

Spacious house for groups-3 mi from CU! Across from Patrick Square!

10.0 out of 10, Exceptional, (13)
"House was clean, spacious and a great location. Will use again if staying in Clemson!"
Spacious house for groups-3 mi from CU! Across from Patrick Square!
Beautiful Home Close To Everything
Interior

Beautiful Home Close To Everything

9.6 out of 10, Exceptional, (165)
"House was close to everything but far enough away from the exit traffic. Very short drive to restaurants or Costco!"
Beautiful Home Close To Everything
Treetop Haven Clemson
Property grounds

Treetop Haven Clemson

10.0 out of 10, Exceptional, (20)
"It was an amazing stay. Beautiful home, lovely host and elegant decor and amenities. "
Treetop Haven Clemson
Travelers Rest Treasure - Pets Welcome Sleeps 8 - 3 Bedroom 2 Bath
Exterior

Travelers Rest Treasure - Pets Welcome Sleeps 8 - 3 Bedroom 2 Bath

10.0 out of 10, Exceptional, (20)
"We thoroughly enjoyed our stay. House is incredibly clean and well appointed with lots of extra touches for guests. Highly recommend!"
Travelers Rest Treasure - Pets Welcome Sleeps 8 - 3 Bedroom 2 Bath
Cozy House Close To Everything Anderson Has To Offer
Private kitchen

Cozy House Close To Everything Anderson Has To Offer

10.0 out of 10, Exceptional, (17)
"Nice cozy home, good central location. Good weekend getaway. Would stay again if in the area"
Cozy House Close To Everything Anderson Has To Offer
Mini Putting Green & Pool Access: Simpsonville Gem
Property grounds

Mini Putting Green & Pool Access: Simpsonville Gem

10.0 out of 10, Exceptional, (2)
"Loved the stay. Primary bath is really nice.Backyard is a bit busy.Pool was very nice family fun.Lots of space for the family to spread out."
Mini Putting Green & Pool Access: Simpsonville Gem
Relaxing Stay on Trade Street
Private kitchen

Relaxing Stay on Trade Street

10.0 out of 10, Exceptional, (13)
"Cozy, comfortable space for three women on an annual get-together. Loved its proximity to town."
Relaxing Stay on Trade Street
The Westfield - Cozy Downtown Greer Retreat
Terrace/patio

The Westfield - Cozy Downtown Greer Retreat

8.0 out of 10, Very good, (1)
"We enjoyed our stay at the westfeild cottage. The home is very comfortable and pets being welcome is a bonus. The only issue we experienced was not being able to walk our dogs in peace because everytime we went outsode, within 2 minutes the neighbor let her 4 dogs out and they didnt seem like the friendliest on the opposite side of the fence. Things did seem a little rushed before our arrival,cleaning wise. There was a dead fly in the fridge, sheets in the dryer, and the soaps were running low...
The price is CA $123
CA $285 total
includes taxes & fees
Sep 3 - Sep 4
The Westfield - Cozy Downtown Greer Retreat
Near Downtown 3 Bedroom Home with King beds+ Parking+Deck
Fridge, microwave, oven, stovetop

Near Downtown 3 Bedroom Home with King beds+ Parking+Deck

10.0 out of 10, Exceptional, (7)
"The weekend stay at this property was overall AMAZING! There was so much space and the house was very very clean ! We ended up cooking both nights and everything we needed was there including seasonings! Let’s just say 10/10 will definitely book again. "
The price is CA $153
CA $399 total
includes taxes & fees
Aug 20 - Aug 21
Near Downtown 3 Bedroom Home with King beds+ Parking+Deck
Convenient Location-Private watch the sun come up over a beautiful pasture
Dining

Convenient Location-Private watch the sun come up over a beautiful pasture

8.8 out of 10, Excellent, (3)
"We really enjoyed our stay at this house. It is very roomy and open. The beds were comfortable. The TV in the master bedroom did not work and the host made sure that she came over and corrected it right away. We will definitely stay here again. I really enjoyed the privacy and the big yard"
Convenient Location-Private watch the sun come up over a beautiful pasture
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Upstate South Carolina Hotel Reviews

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

10/10 Excellent
"Great"
Matthew 1-night trip
Posted 1 day ago
Best Western Plus Clemson Hotel & Conference Center