Title: Upstate South Carolina Vacation Home Rentals : Search Top Private Vacation Homes for Rent | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d553248635975748552.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d553248635975748552.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d553248635975748552.Destination-Travel-Guides) ![Greenville - Spartanburg featuring mountains, views and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Upstate South Carolina Vacation Rentals ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-24&endDate=2025-10-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-10-31&endDate=2025-11-02&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-11-14&endDate=2025-11-16&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-12-12&endDate=2025-12-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Upstate South Carolina Vacation Homes ![Exterior](https://images.trvl-media.com/lodging/88000000/87740000/87739300/87739293/09a4ae60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/88000000/87740000/87739300/87739293/38406fa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/88000000/87740000/87739300/87739293/fafcc84f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87740000/87739300/87739293/c2d0dc23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~ Spartanburg 10/10 Exceptional (44) "Stayed 4 days. Very nice. I would stay again. I didn't know the area but was easy to get everywhere with GPS. Easy check in and out. " CA $125 CA $279 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Spartanburg-Hotels-2-Bedroom-Cozy-Gem-5-Minutes-From-Downtown-Spartanburg.h87739293.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/b7a1f289.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/de9f5026.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/7411cba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/6ec12c0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Welcome To Downtown Pickens close to Clemson and Lake Keowee Pickens 10/10 Exceptional (28) "This house is fantastic. It is in a great location, whether you're staying local, driving into Easley and Greenville, or taking the scenic roads toward the mountains. This was our third stay at this property, and we really love this place. Perhaps the most cherished memory from this most recent stay is showing my daughter fireflies in the evening." CA $152 CA $368 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Pickens-Hotels-Welcome-To-Downtown-Pickens-Close-To-Clemson-And-Lake-Keowee.h89406578.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/ff8281c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/88b08b4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/ec7d22d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/79000000/78140000/78137300/78137271/w4160h2480x0y0-ecbd25bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Blue Bungalow by Unity Park - Newly Renovated Woodside Cotton Mill Village Historic District 9.8/10 Exceptional (74) "Beautiful stay! We will definitely be back " CA $114 CA $287 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Greenville-Hotels-The-Blue-Bungalow-By-Unity-Park-Newly-Renovated.h78137271.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/110000000/109870000/109860500/109860449/bba31fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109870000/109860500/109860449/47e75beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/110000000/109870000/109860500/109860449/e586ef9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/110000000/109870000/109860500/109860449/8a1c1825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Secluded Yurt Hideaway 10 min to Table Rock cleveland 9.4/10 Exceptional (6) "The property was everything we had seen and more. This pet friendly property was remote. Great for pets that need to roam some. They had dog leads, treats towels for our fur babies family" CA $139 CA $470 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Cleveland-Hotels-Secluded-Yurt-Hideaway-10-Min-To-Table-Rock.h109860449.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/79000000/78180000/78175700/78175602/ca5e0e21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/79000000/78180000/78175700/78175602/38a9f184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78180000/78175700/78175602/268d249b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78180000/78175700/78175602/0ebefea8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hobbit Hideaway - Do Something Different! Marietta 10/10 Exceptional (49) "Amazing property quite peaceful perfect for a little get a way!!!! Property had everything you want and outdoor has lots to do!" CA $120 CA $248 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Marietta-Hotels-Hobbit-Hideaway-Do-Something-Different.h78175602.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/78000000/77940000/77937500/77937495/69a716cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/78000000/77940000/77937500/77937495/1242abd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/78000000/77940000/77937500/77937495/abc41a1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, toilet paper](https://images.trvl-media.com/lodging/78000000/77940000/77937500/77937495/9a3533de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apt. near Downtown Greenville (2BR/1BA, 3 beds) Greenville 10/10 Exceptional (11) "It was clean and quiet..I will stay here again. " CA $127 CA $232 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Greenville-Hotels-Apt-Near-Downtown-Greenville.h77937495.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/83000000/82190000/82188100/82188079/w1200h2204x0y0-d7698a34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/83000000/82190000/82188100/82188079/7e21d72d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/83000000/82190000/82188100/82188079/54088e4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/83000000/82190000/82188100/82188079/b267ec3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg Lyman 10/10 Exceptional (39) "We loved this place! Clean and beautiful. The snacks and the candle were just perfect to make our stay the best." CA $126 CA $290 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Lyman-Hotels-Luxury-Getaway-Hot-Tub-Close-To-GSP-Cozy.h82188079.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107350000/107345400/107345371/37f7c8d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/108000000/107350000/107345400/107345371/a80808a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107350000/107345400/107345371/f14ad78f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107350000/107345400/107345371/5ac6cc3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Whole House, sleeps 7, within walking distance to downtown Spartanburg! Spartanburg 10/10 Exceptional (7) "Accommodations were comfortable and had everything we needed. The location is great. " CA $145 CA $353 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Spartanburg-Hotels-Whole-House.h107345371.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100340000/100330600/100330565/b137370a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/101000000/100340000/100330600/100330565/7d94b763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/101000000/100340000/100330600/100330565/c495bdd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100340000/100330600/100330565/9c2d3cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sunny Side Cottage: Cozy Stay by Anderson U! Anderson 9.8/10 Exceptional (19) "This home is older and as with all older homes that aren’t remodeled, it has an unusual layout. It’s in a cute neighborhood and was located close to our destination. Iwas clean and decorated nicely and the beds were comfortable. We would stay there again. " CA $141 CA $506 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Anderson-Hotels-Charming-Bungalow-One-Block-To-Anderson-University.h100330565.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/104000000/103160000/103157900/103157886/148da8bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/104000000/103160000/103157900/103157886/1d01e9bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/104000000/103160000/103157900/103157886/6516543e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103160000/103157900/103157886/56576d34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Apple Cottage Pickens 9.8/10 Exceptional (25) "The cottage was so cozy. So cute and well stocked with all we needed. Loved our stay. " CA $125 CA $248 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Pickens-Hotels-Country-Apple-Cottage.h103157886.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/94000000/93430000/93428900/93428851/330d2f29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/94000000/93430000/93428900/93428851/9be6cf5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/94000000/93430000/93428900/93428851/7ec8d179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/94000000/93430000/93428900/93428851/955c849c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private family, pet friendly with fenced yard near Limestone College and Outlets Gaffney 9.8/10 Exceptional (23) "It is a really nice place and in a quiet area. Very cute backyard. Would stay again!! " CA $112 CA $286 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Gaffney-Hotels-Private-Family.h93428851.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/74000000/73980000/73974400/73974359/b04bd3c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/74000000/73980000/73974400/73974359/333b582b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/74000000/73980000/73974400/73974359/a902f25a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/74000000/73980000/73974400/73974359/4ada4bf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private, pet-friendly adorable getaway mins to downtown Greenville 9.6/10 Exceptional (108) "An adorable cottage in an older established neighborhood. So close to downtown Greenville, parks, restaurants, etc. lots to explore and do. " CA $211 CA $437 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Greenville-Hotels-Private.h73974359.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111250000/111242400/111242365/d86f82a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/112000000/111250000/111242400/111242365/0d4dcfc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111242400/111242365/bebb8929.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/112000000/111250000/111242400/111242365/3703494f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Near Downtown 3 Bedroom Home with King beds+ Parking+Deck Greenville 10/10 Exceptional (9) "This house was the perfect size for our family of five. Great location to access downtown Greenville(9 min away) and Traveler’s Rest(9 min away). " CA $135 CA $382 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Greenville-Hotels-Cozy-Bright-3-Bedroom-Home-With-Parking.h111242365.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/102000000/101250000/101242300/101242247/224c0e9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/102000000/101250000/101242300/101242247/0f0e2204.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/102000000/101250000/101242300/101242247/60cdddcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, in-room safe, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/102000000/101250000/101242300/101242247/eb5bdfd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### CHIC✨️|Bikes|ParkPass|Lake|PizzaOven|BlackStone|YouTubeTV Greenville 10/10 Exceptional (14) "The house is adorable- clean and tastefully decorated. It is fully stocked with anything you could ever need- and then some. Nice private backyard. The beds were so comfortable!! We enjoyed our stay and look forward to coming back!" CA $184 CA $536 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Greenville-Hotels-CHIC3MiDwtnSRTBikesParkPassPizzaOvenKing.h101242247.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/103000000/102560000/102557200/102557173/e38cd5c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/103000000/102560000/102557200/102557173/63e64e17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, dishwasher](https://images.trvl-media.com/lodging/103000000/102560000/102557200/102557173/eb73e0bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/103000000/102560000/102557200/102557173/7fc0df84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pet-Friendly Cabin in Marietta w/ Porch Swings Cleveland 10/10 Exceptional (1) "Accurate listing, easy to find! " CA $116 CA $370 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Cleveland-Hotels-Pet-Friendly-Cabin-In-Marietta-W-Porch-Swings.h102557173.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/103000000/102140000/102137100/102137027/27d2c52a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/103000000/102140000/102137100/102137027/bb5d7201.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102140000/102137100/102137027/455a379a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102140000/102137100/102137027/53a9cfc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Downtown Easley Home Easley 8.6/10 Excellent (4) "The house was great for our one night stay. The house was clean and stocked. We had to leave early and didn't spend the entire night. But the host was gracious and easy to communicate with. Would recommend!" CA $125 CA $331 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Easley-Hotels-Downtown-Easley-Home.h102137027.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111260000/111256000/111255940/0326b828.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/112000000/111260000/111256000/111255940/dbad2f0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111260000/111256000/111255940/9777f063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/112000000/111260000/111256000/111255940/1b8141e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carolina Cottage-Entire Home-Close to Downtown Spartanburg Spartanburg 9.2/10 Wonderful (5) "Great spot for a stay in Spartanburg." CA $154 CA $363 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Spartanburg-Hotels-Carolina-Cottage-Entire-Home-Close-To-Downtown-Spartanburg.h111255940.Hotel-Information) ![Signature House, 4 Bedrooms, Patio | Living room](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/877220d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/63caaad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 4 Bedrooms, Patio | In-room dining](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/84421426.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 4 Bedrooms, Patio | Private kitchen](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/f8ba8fcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Hartwell Frank Howard Home Clemson Anderson [](https://www.expedia.ca/Anderson-Hotels-Lake-Hartwell-Frank-Howard-Home-Clemson.h89473761.Hotel-Information) ![Smart TV, video games, Netflix, streaming services](https://images.trvl-media.com/lodging/88000000/87140000/87135300/87135240/a93dcf1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87140000/87135300/87135240/e3d40971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87140000/87135300/87135240/7fb74463.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/88000000/87140000/87135300/87135240/16b6d6fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy 2 bedroom home near downtown Gaffney. Gaffney 9.6/10 Exceptional (28) "Very nice Property. Very spacious and beds were super comfortable. Would definitely stay again, thank you so much for being such a awesome host." CA $139 CA $316 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Gaffney-Hotels-Cozy-2-Bedroom-Home-Near-Downtown-Gaffney.h87135240.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/104000000/103650000/103644700/103644605/ae5e5fc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/104000000/103650000/103644700/103644605/903eab47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/104000000/103650000/103644700/103644605/bf692c18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/104000000/103650000/103644700/103644605/810d8862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Family-Friendly 3/2 Home Near Prisma, Fenced Yard Greenville 10/10 Exceptional (3) "The place was perfect! Had everything we needed and was extremely clean!" CA $139 CA $429 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Greenville-Hotels-Family-Friendly-32-Home-Near-Prisma.h103644605.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-30&endDate=2025-10-31®ionId=553248635975748552&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Private-Vacation-Homes.d553248635975748552-aaPrivateVacationHomes.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Private-Vacation-Homes.d553248635975748552-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Upstate South Carolina Hotel Reviews ![Best Western Plus Greenville I-385 Inn & Suites](//images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Excellent" [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Woodspring Suites Greenville Airport](//images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/69b6f44b_y.jpg) ### Woodspring Suites Greenville Airport 10/10 Excellent "It’s a great place to stay" [](https://expedia.ca/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) ![Hilton Greenville](//images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "The staff were very friendly. I checked out and left my phone in the room and they allowed me to go back in the room, no hassle at all to retrieve my phone!!" [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](//images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "Room was very clean, hotel staff was very nice, overall great experience!! We will be back!!" [](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Hyatt Place Greenville Downtown](//images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/dac522c0_y.jpg) ### Hyatt Place Greenville Downtown 10/10 Excellent "Clean" [](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information) ![Hyatt Regency Greenville](//images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "Clean room, beautiful view!" [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](//images.trvl-media.com/lodging/1000000/10000/1400/1379/91409d5a_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 10/10 Excellent "Clean room" [](https://expedia.ca/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Clean rooms" [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Grand Bohemian Lodge Greenville, Autograph Collection](//images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3_y.jpg) ### Grand Bohemian Lodge Greenville, Autograph Collection 10/10 Excellent "We celebrated our 36th anniversary; we did not share that with the hotel. We had a wonderful day, enjoyed a welcome complimentary fall drink before heading over the bridge to Jianna's for a wonderful meal. Came back to a comfy bed with a fluffy comforter. We did not stay for coffee, which would have been nice, but we had a nice stay." [](https://expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ## Find out more about Upstate South Carolina ## Upstate South Carolina Vacation Homes information | Number of reviews | | | --- | --- | | Accommodation | Vacation Homes | | Lowest Price | | | Highest Price | | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Anglewood Hotels](https://www.expedia.ca/Anglewood-Hotels.d553248635975857985.Travel-Guide-Hotels) - [Cross Anchor Hotels](https://www.expedia.ca/Cross-Anchor-Hotels.d553248635519281641.Travel-Guide-Hotels) - [Cottages in Duncan](https://www.expedia.ca/Duncan-Cottages.d6761-aaCottages.Travel-Guide-Accommodation) - [Lodges in Duncan](https://www.expedia.ca/Duncan-Lodges.d6761-aaLodges.Travel-Guide-Accommodation) - [Aparthotels in Enoree](https://www.expedia.ca/Enoree-Apart-Hotels.d3000353124-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Enoree](https://www.expedia.ca/Enoree-Bed-And-Breakfast.d3000353124-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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[Flights from Oakland (OAK) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/oak/spa/oakland-to-spartanburg) - [Flights from Owensboro (OWB) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/owb/spa/owensboro-to-spartanburg) - [Flights from Portland (PDX) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/pdx/spa/portland-to-spartanburg) - [Flights from Philadelphia (PHL) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/phl/spa/philadelphia-to-spartanburg) - [Flights from Seattle (SEA) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/sea/spa/seattle-to-spartanburg) - [Flights from Syracuse (SYR) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/syr/spa/syracuse-to-spartanburg) - [Flights from Teterboro (TEB) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/teb/spa/teterboro-to-spartanburg) - [Flights from Tampa (TPA) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/tpa/spa/tampa-to-spartanburg) - [Flights from Tri-Cities (TRI) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/tri/spa/tri-cities-to-spartanburg) - [Flights from Trenton (TTN) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/ttn/spa/trenton-to-spartanburg) - [Flights from Tupelo (TUP) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/tup/spa/tupelo-to-spartanburg) - [Flights from Tokyo (TYO) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/tyo/spa/tokyo-to-spartanburg) - [Flights from Valdosta (VLD) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/vld/spa/valdosta-to-spartanburg) - [Flights from Halifax (YHZ) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/yhz/spa/halifax-to-spartanburg) - [Flights from Montreal (YUL) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/yul/spa/montreal-to-spartanburg) - [Flights from Vancouver (YVR) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/yvr/spa/vancouver-to-spartanburg) - [Flights from Toronto (YYZ) to Spartanburg (SPA)](https://www.expedia.ca/lp/flights/yyz/spa/toronto-to-spartanburg) - [295 Sports Complex](https://www.expedia.ca/295-Sports-Complex-Spartanburg.d6245676.Vacation-Attraction) - 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