Title: Book the Best PET FRIENDLY Hotels in Upstate South Carolina, SC from CA $95 - Upstate South Carolina Dog-Friendly Hotels | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d553248635975748552.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d553248635975748552.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d553248635975748552.Destination-Travel-Guides) ![It is only a 1 mile hike to this beauty. View a video about it here: https://www.hdcarolina.com/episode/riley-moore-falls #Waterfall](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Watts # Find Pet-friendly Hotels in Upstate South Carolina, SC from CA $95 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Pet-friendly Hotels Tonight [Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-12-18&endDate=2025-12-19&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-12-19&endDate=2025-12-20&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-12-19&endDate=2025-12-21&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635975748552&startDate=2025-12-26&endDate=2025-12-28&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina pet-friendly hotels ![Reception](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/2fa8ed98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/33c2ff7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/752d9078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/bd6af703.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Spartanburg-North I-85 [](https://www.expedia.ca/Spartanburg-Hotels-Hampton-Inn-Spartanburg-North-I-85.h281618.Hotel-Information) Spartanburg 8.8/10 Excellent (1004) "Everything was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Annie M CA $107 CA $119 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/Spartanburg-Hotels-Hampton-Inn-Spartanburg-North-I-85.h281618.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/db449d90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/6abd26aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/ad742419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/589bd84f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) Seneca 9.0/10 Wonderful (1001) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gene CA $150 CA $186 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/cd259adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/1ccff62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/5a8cea9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/573947b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Gaffney [](https://www.expedia.ca/Gaffney-Hotels-Hampton-Inn-Gaffney.h424882.Hotel-Information) Gaffney 8.8/10 Excellent (669) "Clean room, great staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) gary CA $123 CA $134 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Gaffney-Hotels-Hampton-Inn-Gaffney.h424882.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26900/26875/a5fc35a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26900/26875/d789a59c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/26900/26875/95b4cb26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/26900/26875/ea1edcbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Clinton - Laurens I-26 [](https://www.expedia.ca/Clinton-Hotels-Quality-Inn-Clinton.h26875.Hotel-Information) Clinton 7.4/10 Good (518) "Very friendly staff and places to eat close by! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Burit CA $81 CA $95 total includes taxes & fees Jan 10 - Jan 11, 2026 [](https://www.expedia.ca/Clinton-Hotels-Quality-Inn-Clinton.h26875.Hotel-Information) ![Free breakfast](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/e417f297.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout drapes, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/66ea89ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/60389240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/70604dbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Anderson/ Alliance Business Park [](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Anderson-North.h3629858.Hotel-Information) Anderson 9.2/10 Wonderful (806) "Very comfortable stay convenient to Greenville Spartanburg Airport." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rick CA $156 CA $173 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Anderson-North.h3629858.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1230000/1228400/1228331/a9050d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1230000/1228400/1228331/b84140b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1230000/1228400/1228331/2092b566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1230000/1228400/1228331/a97374de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Clinton - I-26 [](https://www.expedia.ca/Clinton-Hotels-Hampton-Inn-Suites-Clinton-I-26.h1228331.Hotel-Information) Clinton 9.0/10 Wonderful (699) "The room was very clean and the staff was great. The breakfast was enjoyable and had good variety. I will definitely stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cathleen CA $146 CA $163 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/Clinton-Hotels-Hampton-Inn-Suites-Clinton-I-26.h1228331.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/5971f25f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/1fc30205.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/92684d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Concierge desk](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/1d70fbe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd. [](https://www.expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information) Greenville 8.4/10 Very good (72) "Love this new hotel. Safe good breakfast and friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dorothea CA $98 CA $111 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/81c4f249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/f6f7c8c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/eab53b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Seneca Clemson Area US-123 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) Downtown 8.0/10 Very good (665) "Friendly check in, clean room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) connie CA $101 CA $120 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/59f41330.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/7796ec2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/0a2d26b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/2b4321e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Anderson/Clemson [](https://www.expedia.ca/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) Anderson 8.2/10 Very good (1002) "Clean room, staff nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Selena CA $110 CA $122 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b0e15e12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b840578e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Double Beds, Non Smoking | Living area](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/f2d60448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites Greenville Golf Resort & Conference Center [](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) Greenville 9.0/10 Wonderful (1020) "Great room, staff and location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Neil CA $130 CA $143 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-01&endDate=2026-01-02®ionId=553248635975748552&adults=2&amenities=PETS&sort=RECOMMENDED&openPlayBack=true) ## Top Upstate South Carolina Hotel Reviews ![Aloft Greenville Downtown](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51_y.jpg) ### Aloft Greenville Downtown 10/10 Excellent "Clean Rooms, courteous staff, and Great Location. Only negative of the stay was the Shower had Low Pressure. " [](https://expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "Clean" [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Clean property and close to many,many shopping and dining options. Hotel staff extremely friendly. " [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "The room was immaculate. TV wouldn't change from the menu screen, that would be my only complaint. " [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "The room was very nice. Very spacious. The staff was very friendly. The location was great too. " [](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![Best Western Greenville Airport Inn](https://images.trvl-media.com/lodging/1000000/10000/800/708/338fc74f_y.jpg) ### Best Western Greenville Airport Inn 10/10 Excellent "Good " [](https://expedia.ca/Greenville-Hotels-Best-Western-Greenville-Airport-Inn.h708.Hotel-Information) ![The Westin Poinsett Greenville](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/3e47bf88_y.jpg) ### The Westin Poinsett Greenville 10/10 Excellent "Awesome place " [](https://expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - More ways to book - [Anglewood Hotels ](https://www.expedia.ca/Anglewood-Hotels.d553248635975857985.Travel-Guide-Hotels) - [Hotels with a Pool in South Carolina ](https://www.expedia.ca/Destinations-In-South-Carolina-Hotel-With-Pool.0-0-d242-tHotelwithPool.Hotel-Filter-Destinations) - 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