Title: Book the Best HISTORIC Hotels in Upstate South Carolina in 2026 | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides) ![The view from Caesars Head after a storm](https://images.trvl-media.com/place/553248621532656715/293b23c7-6024-49ab-80cb-4ee292c1b5a3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michelle Hendrix # Find Historic Hotels in Upstate South Carolina, SC from CA $169 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Historic Hotels Tonight [Dec 17 - Dec 18](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-12-17&endDate=2025-12-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina historic hotels ![Exterior](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558616/ff716430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed (Low Floor)](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558616/17641a6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558616/w6000h3996x0y0-b212d0d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558616/78b30d8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Clemson by IHG [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Suites-Clemson.h2558616.Hotel-Information) Clemson 8.8/10 Excellent (950) "Had a great stay at this hotel. Conveniently located near restaurants. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly CA $162 CA $180 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Suites-Clemson.h2558616.Hotel-Information) ![Cookware/dishes/utensils, dining tables](https://images.trvl-media.com/lodging/103000000/102560000/102557000/102556973/e2f65084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102560000/102557000/102556973/52a1caed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/103000000/102560000/102557000/102556973/807bf8b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/103000000/102560000/102557000/102556973/6a23ddca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chic Downtown 2BR Condo walk to The Well Arena [](https://www.expedia.ca/Greenville-Hotels-Chic-Downtown-2BR-Condo-Walk-To-The-Well-Arena.h102556973.Hotel-Information) Greenville Downtown 9.8/10 Exceptional (6) "Condo is very comfortable & location was good. Stayed two nights." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie C. CA $174 CA $396 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Greenville-Hotels-Chic-Downtown-2BR-Condo-Walk-To-The-Well-Arena.h102556973.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/670000/663800/663745/88e41c80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Brass Giraffe](https://images.trvl-media.com/lodging/1000000/670000/663800/663745/12c9f43e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/670000/663800/663745/e46ad4dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/1000000/670000/663800/663745/38a49fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pettigru Place Bed & Breakfast [](https://www.expedia.ca/Greenville-Hotels-Pettigru-Place-Bed-Breakfast.h663745.Hotel-Information) Greenville Downtown 10/10 Exceptional (125) "Room was great, clean and comfortable. Staff was outstanding. Great breakfast as well. Super place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Blake CA $286 CA $315 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Greenville-Hotels-Pettigru-Place-Bed-Breakfast.h663745.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/113000000/112030000/112024200/112024164/12133b3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/113000000/112030000/112024200/112024164/6657b1c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/113000000/112030000/112024200/112024164/896cebe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112030000/112024200/112024164/19e28a5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1br Apt in Historic Triplex - 5min walk Swamp Rabbit Trail, 15min walk to dntwn [](https://www.expedia.ca/Greenville-Hotels-1br-Apt-In-Historic-Triplex-5min-Walk-Swamp-Rabbit-Trail.h112024164.Hotel-Information) Greenville Downtown 8.6/10 Excellent (4) "This was a pleasant tri-plex. However it’s off a major road and there is a ton of street noise. The home was comfortable and clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tina CA $151 CA $363 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Greenville-Hotels-1br-Apt-In-Historic-Triplex-5min-Walk-Swamp-Rabbit-Trail.h112024164.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/30000000/29940000/29935300/29935238/38c8a8b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player, books, video library](https://images.trvl-media.com/lodging/30000000/29940000/29935300/29935238/6c880f48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/30000000/29940000/29935300/29935238/6d8a33de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/30000000/29940000/29935300/29935238/21a53dc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Make Memories on Mulberry [](https://www.expedia.ca/Greenville-Hotels-Make-Memories-On-Mulberry.h29935238.Hotel-Information) Greenville 10/10 Exceptional (98) "Beautiful home just a 5 minute Uber to anywhere downtown. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony R. CA $172 CA $310 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Greenville-Hotels-Make-Memories-On-Mulberry.h29935238.Hotel-Information) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103660000/103651700/103651672/236249bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103660000/103651700/103651672/1ad80e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/104000000/103660000/103651700/103651672/6f61b169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103660000/103651700/103651672/cf9dd524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Downtown Loft for Two + Pets, Walk to Main St [](https://www.expedia.ca/Greenville-Hotels-Cozy-Downtown-Loft-For-Two-Pets.h103651672.Hotel-Information) Greenville Downtown 8.8/10 Excellent (5) "Just a great time in Greenville and with a great place to stay; very comfortable in a great location. We loved having such a well supplied kitchen to cook in. The host is top notch, always with quick answers to what seemed like a lot of questions. Very welcoming; we'll surely be back and highly recommend the Loft, especially for couples looking for something special." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bradley B. CA $113 CA $276 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Greenville-Hotels-Cozy-Downtown-Loft-For-Two-Pets.h103651672.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/113000000/112030000/112023800/112023725/b087d0b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/113000000/112030000/112023800/112023725/79a9be1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112030000/112023800/112023725/852f2f1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112030000/112023800/112023725/5aaa51c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1 bedroom apt, Steps from Swamp Rabbit Trail, 15 minute walk to Main st. [](https://www.expedia.ca/Greenville-Hotels-1-Bedroom-Apt.h112023725.Hotel-Information) Greenville Downtown 10/10 Exceptional (5) CA $114 CA $330 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Greenville-Hotels-1-Bedroom-Apt.h112023725.Hotel-Information) ![Smart TV, books](https://images.trvl-media.com/lodging/113000000/112030000/112024400/112024327/1a533530.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112030000/112024400/112024327/30159069.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/113000000/112030000/112024400/112024327/47bd746a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/113000000/112030000/112024400/112024327/2e1cabf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2bed Apt - 5 min walk to Swamp Rabbit - 15min walk to downtown - 3min walk BSWA [](https://www.expedia.ca/Greenville-Hotels-2bed-Apt-5-Min-Walk-To-Swamp-Rabbit-15min-Walk-To-Downtown-3min-Walk-BSWA.h112024327.Hotel-Information) Greenville Downtown 10/10 Exceptional (8) "This rental was a perfect spot for exploring Greenville- So close to so many wonderful places. Reedy River Falls Swamp Rabbit trail and wonderful restaurants and shopping. Perfect base camp - Very Clean, comfortable beds. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charlotte S. CA $165 CA $462 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Greenville-Hotels-2bed-Apt-5-Min-Walk-To-Swamp-Rabbit-15min-Walk-To-Downtown-3min-Walk-BSWA.h112024327.Hotel-Information) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/81000000/80360000/80354000/80353961/71cf4d32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/81000000/80360000/80354000/80353961/e737cd70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/81000000/80360000/80354000/80353961/644bb751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, memory foam beds, desk, blackout drapes](https://images.trvl-media.com/lodging/81000000/80360000/80354000/80353961/f484ef47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Designer Retreat in Quaint Historic District w Front Porch Dining under the oaks [](https://www.expedia.ca/Greenville-Hotels-Designer-Retreat-In-Quaint-Historic-District-W-Front-Porch-Dining-Under-The-Oaks.h80353961.Hotel-Information) Greenville Downtown 10/10 Exceptional (71) "The home was stunning and decorated beautifully. Wonderful location and the communication with host was a pleasure. We will stay here again! Everything was superb. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Staci B. CA $480 CA $920 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Greenville-Hotels-Designer-Retreat-In-Quaint-Historic-District-W-Front-Porch-Dining-Under-The-Oaks.h80353961.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1220000/1213000/1212931/c321176c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1220000/1213000/1212931/2b6111ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1213000/1212931/726f3d0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1220000/1213000/1212931/b23b9566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn on the Square, an Ascend Collection Hotel [](https://www.expedia.ca/Greenwood-Hotels-Inn-On-The-Square.h1212931.Hotel-Information) Uptown Greenwood 9.2/10 Wonderful (710) "It was a very clean and beautiful lace to stay. We were there for our honeymoon " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tracy CA $152 CA $169 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/Greenwood-Hotels-Inn-On-The-Square.h1212931.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-31&endDate=2026-01-01®ionId=6057939&adults=2&specialized_stays_group_explore=historic_property&sort=RECOMMENDED&openPlayBack=true) ## Top Upstate South Carolina Hotel Reviews ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "It was great! Comfortable and clean!" [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Aloft Greenville Downtown](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51_y.jpg) ### Aloft Greenville Downtown 10/10 Excellent "Clean Rooms, courteous staff, and Great Location. Only negative of the stay was the Shower had Low Pressure. " [](https://expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "Clean" [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Clean property and close to many,many shopping and dining options. Hotel staff extremely friendly. " [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "The room was immaculate. TV wouldn't change from the menu screen, that would be my only complaint. " [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "The room was very nice. Very spacious. The staff was very friendly. The location was great too. " [](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1379/91409d5a_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 10/10 Excellent "Staff was great, awesome customer service! " [](https://expedia.ca/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Amazing staff and clean room" [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Best Western Greenville Airport Inn](https://images.trvl-media.com/lodging/1000000/10000/800/708/338fc74f_y.jpg) ### Best Western Greenville Airport Inn 10/10 Excellent "Good " [](https://expedia.ca/Greenville-Hotels-Best-Western-Greenville-Airport-Inn.h708.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Hotels with a Pool in South Carolina ](https://www.expedia.ca/Destinations-In-South-Carolina-Hotel-With-Pool.0-0-d242-tHotelwithPool.Hotel-Filter-Destinations) - [Hotels with Balconies in South Carolina ](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Balconies.0-0-d242-tHotelswithBalconies.Hotel-Filter-Destinations) - 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