Title: Book the Best Upstate South Carolina FAMILY FRIENDLY Hotels from CA $86 - Kid-Friendly Hotels in Upstate South Carolina, SC | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides) ![The view from Caesars Head after a storm](https://images.trvl-media.com/place/553248621532656715/293b23c7-6024-49ab-80cb-4ee292c1b5a3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michelle Hendrix # Find Family Hotels in Upstate South Carolina, SC from CA $86 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Family Hotels Tonight [Dec 2 - Dec 3](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-12-02&endDate=2025-12-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) Tomorrow [Dec 3 - Dec 4](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-12-03&endDate=2025-12-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) ## Top Upstate South Carolina Family Hotels ![Free daily full breakfast](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/589dc000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, desk, blackout drapes](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/bd03801f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/3ccb6df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/f5139881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Gaffney by IHG Gaffney 8.6/10 Excellent (412) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy CA $103 CA $112 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/ac0c08fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/e91d409a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/ca99d7c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Greenville I-385 Inn & Suites Greenville 9.0/10 Wonderful (1420) "Loved my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Himani CA $146 CA $161 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/cd259adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/0304ce09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/1ebed4bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/c05bf676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Gaffney Gaffney 8.8/10 Excellent (664) "Clean room, great staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) gary CA $122 CA $133 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Gaffney-Hotels-Hampton-Inn-Gaffney.h424882.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/f59bfe6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/36a85341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/586dbae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/0007de95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Greenville Woodruff Road Greenville 9.4/10 Exceptional (1013) "The hotel was excellent m." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brittiany CA $159 CA $175 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Greenville-Hotels-DoubleTree-By-Hilton-Greenville-Woodruff-Road.h50828647.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/9fe06894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/e45ab30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/a9307e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Seneca Clemson Univ Area Seneca 9.4/10 Exceptional (204) "Nice hotel by the lake" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $168 CA $184 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/62500/62445/267632f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/62500/62445/3633bac6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/70000/62500/62445/f4e7ad54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/62500/62445/9c0d4b0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Union US Hwy 176 Union 7.4/10 Good (239) "My reservation was confirmed for two queen beds. When I arrived, the only room available was a room with a king bed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $77 CA $86 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Union-Hotels-Quality-Inn-Union-US-Hwy-176.h62445.Hotel-Information) ![In-room safe, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0de8634b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/ee0e0eea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/db1c155b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson Clemson 9.8/10 Exceptional (736) "Wonderful staff, great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shelly CA $234 CA $260 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/800/708/c6283d85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, blackout drapes, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/1000000/10000/800/708/cd95f3b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/800/708/2fe691fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/800/708/4bfc6efb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Greenville Airport Inn Greenville 7.6/10 Good (1010) "This was the best room we stayed on our whole trip had a great deal smoking room and it was the best breakfast buffet that we had fresh yogurt everything about this hotel was nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vanessa CA $101 CA $111 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Greenville-Hotels-Best-Western-Greenville-Airport-Inn.h708.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/e51fff20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/ca80b104.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/76bc86a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/7f8f2b8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Clemson - University Area Clemson 8.2/10 Very good (1008) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda CA $131 CA $145 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/a3eeb266.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/96c48b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking (1 King Bed)](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/b624adce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/b0a8f9c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Greenville Haywood Greenville 7.4/10 Good (1127) "The staff is so friendly and they are very accommodating. Eddie from the front desk is always kind. Good breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dorothea CA $95 CA $105 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-16&endDate=2025-12-17®ionId=6057939&adults=2&travelerType=family_friendly&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Limited-time deals: save up to 50% on select hotels [Book now](https://expedia.ca/deals?rfrr=AFFINITY_BF_PROMO_6057939) ## Top Upstate South Carolina Hotel Reviews ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Clean room! Nice place!" [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "The staff is so friendly and they are very accommodating. Eddie from the front desk is always kind. Good breakfast " [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "First time staying here the guest service lady was very nice from the first call when I called the office up until check it !!!" [](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Smooth and perfect. Queen Suite is par excellence. Neat clean and all in place and more than what was expected. " [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Drury Inn & Suites Greenville](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Room was nice and clean. Happy hour was v great" [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Beautiful place, awesome staff!" [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Embassy Suites by Hilton Greenville Downtown Riverplace](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89_y.jpg) ### Embassy Suites by Hilton Greenville Downtown Riverplace 10/10 Excellent "Great stay. Enjoyed Greenville and the Embassy Suites" [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![Aloft Greenville Downtown](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51_y.jpg) ### Aloft Greenville Downtown 10/10 Excellent "I had two rooms booked and have been asked to review each booking separately - which I will not do. We loved the hotel. Room designs were excellent as were all the furnishings. We particularly enjoyed the bar and appreciate the reasonable drink prices. The bartenders were great! Unfortunately we are not breakfast eaters and, therefore cannot review the breakfast. The entire staff was terrific and we will return! Thanks so much for your first class hospitality!" [](https://expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "They did a wonderful job everything was great!!!" 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[Waterpark Hotels in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Waterpark-Hotels.0-n6348006-0-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Hotels near Haywood Mall](https://www.expedia.ca/Haywood-Mall-Hotels.0-l6130785-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Mauldin](https://www.expedia.ca/Mauldin-Hotels-Cheap-Hotels.0-0-d183944-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Mauldin](https://www.expedia.ca/Mauldin-Hotels-Luxury-Hotel.0-0-d183944-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Mauldin](https://www.expedia.ca/Mauldin-Hotels-Pet-Friendly-Hotel.0-0-d183944-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Mauldin](https://www.expedia.ca/Mauldin-Hotels-Spa-Hotel.0-0-d183944-tSpaHotel.Travel-Guide-Filter-Hotels) - [Mauldin Hotels](https://www.expedia.ca/Mauldin-Hotels.d183944.Travel-Guide-Hotels) - [Hotels near Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Prisma-Health-Greenville-Memorial-Hospital-Hotels.0-l553248635941390934-0.Travel-Guide-Filter-Hotels) - [Hotels near Shriners Hospitals for Children Greenville](https://www.expedia.ca/Shriners-Hospitals-For-Children-Greenville-Hotels.0-l704436698448793600-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Boutique-Hotel.0-0-d6239-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Cheap-Hotels.0-0-d6239-tCheapHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Golf-Hotel.0-0-d6239-tGolfHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Luxury-Hotel.0-0-d6239-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Pet-Friendly-Hotel.0-0-d6239-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Spa-Hotel.0-0-d6239-tSpaHotel.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Wedding-Hotels.0-0-d6239-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Flights from Donaldson Center](https://www.expedia.ca/lp/airports/gdc/flights-from-donaldson-center-airport) - [Flights from Greenville Downtown](https://www.expedia.ca/lp/airports/gmu/flights-from-greenville-downtown-airport) - [Flights from Mauldin](https://www.expedia.ca/lp/flights/183944/flights-from-mauldin) - [Flights from Anderson (AND) to Greenville (GDC)](https://www.expedia.ca/lp/flights/and/gdc/anderson-to-greenville) - [Flights from Anderson (AND) to Greenville (GMU)](https://www.expedia.ca/lp/flights/and/gmu/anderson-to-greenville) - [Flights from Atlanta (ATL) to Greenville (GMU)](https://www.expedia.ca/lp/flights/atl/gmu/atlanta-to-greenville) - [Flights from Asheville (AVL) to Greenville (GDC)](https://www.expedia.ca/lp/flights/avl/gdc/asheville-to-greenville) - [Flights from Birmingham (BHM) to Greenville (GMU)](https://www.expedia.ca/lp/flights/bhm/gmu/birmingham-to-greenville) - 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Airport (EWR) to Greenville (GDC)](https://www.expedia.ca/lp/flights/ewr/gdc/newark-liberty-intl-airport-to-greenville) - [Flights from Rome (FCO) to Greenville (GDC)](https://www.expedia.ca/lp/flights/fco/gdc/rome-to-greenville) - [Flights from Gatlinburg (GKT) to Greenville (GDC)](https://www.expedia.ca/lp/flights/gkt/gdc/gatlinburg-to-greenville) - [Flights from Gatlinburg (GKT) to Greenville (GMU)](https://www.expedia.ca/lp/flights/gkt/gmu/gatlinburg-to-greenville) - [Flights from Greenwood (GRD) to Greenville (GDC)](https://www.expedia.ca/lp/flights/grd/gdc/greenwood-to-greenville) - [Flights from Greenwood (GRD) to Greenville (GMU)](https://www.expedia.ca/lp/flights/grd/gmu/greenwood-to-greenville) - [Flights from Islip (ISP) to Greenville (GMU)](https://www.expedia.ca/lp/flights/isp/gmu/islip-to-greenville) - [Flights from Jacksonville (JAX) to Greenville (GMU)](https://www.expedia.ca/lp/flights/jax/gmu/jacksonville-to-greenville) - [Flights from New York (JFK) to Greenville (GDC)](https://www.expedia.ca/lp/flights/jfk/gdc/new-york-to-greenville) - [Flights from New York (JFK) to Greenville (GMU)](https://www.expedia.ca/lp/flights/jfk/gmu/new-york-to-greenville) - [Flights from Las Vegas (LAS) to Greenville (GDC)](https://www.expedia.ca/lp/flights/las/gdc/las-vegas-to-greenville) - [Flights from Pickens (LQK) to Greenville (GDC)](https://www.expedia.ca/lp/flights/lqk/gdc/pickens-to-greenville) - [Flights from Orlando (MCO) to Greenville (GDC)](https://www.expedia.ca/lp/flights/mco/gdc/orlando-to-greenville) - [Flights from Manteo (MEO) to Greenville (GMU)](https://www.expedia.ca/lp/flights/meo/gmu/manteo-to-greenville) - [Flights from Miami (MIA) to Greenville (GDC)](https://www.expedia.ca/lp/flights/mia/gdc/miami-to-greenville) - [Flights from Miami (MIA) to Greenville (GMU)](https://www.expedia.ca/lp/flights/mia/gmu/miami-to-greenville) - [Flights from New Orleans (MSY) to Greenville (GMU)](https://www.expedia.ca/lp/flights/msy/gmu/new-orleans-to-greenville) - [Flights from Chicago (ORD) to Greenville (GDC)](https://www.expedia.ca/lp/flights/ord/gdc/chicago-to-greenville) - [Flights from Norfolk (ORF) to Greenville (GMU)](https://www.expedia.ca/lp/flights/orf/gmu/norfolk-to-greenville) - [Flights from West Palm Beach (PBI) to Greenville (GMU)](https://www.expedia.ca/lp/flights/pbi/gmu/west-palm-beach-to-greenville) - [Flights from Philadelphia (PHL) to Greenville (GMU)](https://www.expedia.ca/lp/flights/phl/gmu/philadelphia-to-greenville) - [Flights from Raleigh (RDU) to Greenville (GMU)](https://www.expedia.ca/lp/flights/rdu/gmu/raleigh-to-greenville) - [Flights from Rocky Mount (RWI) to Greenville (GMU)](https://www.expedia.ca/lp/flights/rwi/gmu/rocky-mount-to-greenville) - [Flights from San Antonio (SAT) to Greenville (GDC)](https://www.expedia.ca/lp/flights/sat/gdc/san-antonio-to-greenville) - [Flights from Savannah (SAV) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sav/gmu/savannah-to-greenville) - [Flights from Schenectady (SCH) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sch/gmu/schenectady-to-greenville) - [Flights from Louisville (SDF) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sdf/gmu/louisville-to-greenville) - [Flights from Sanford (SFM) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sfm/gmu/sanford-to-greenville) - [Flights from Newburgh (SWF) to Greenville (GMU)](https://www.expedia.ca/lp/flights/swf/gmu/newburgh-to-greenville) - [Flights from Montreal (YUL) to Greenville (GMU)](https://www.expedia.ca/lp/flights/yul/gmu/montreal-to-greenville) - [Flights from Vancouver (YVR) to Greenville (GMU)](https://www.expedia.ca/lp/flights/yvr/gmu/vancouver-to-greenville) - [Flights from Toronto (YYZ) to Greenville (GDC)](https://www.expedia.ca/lp/flights/yyz/gdc/toronto-to-greenville) - [Flights from Toronto (YYZ) to Greenville (GMU)](https://www.expedia.ca/lp/flights/yyz/gmu/toronto-to-greenville) - [7th Inning Splash Waterpark](https://www.expedia.ca/7th-Inning-Splash-Waterpark-Piedmont.d553248621532656702.Vacation-Attraction) - [Central Vacations](https://www.expedia.ca/Central.d10503.Destination-Travel-Guides) - [Discovery Island Water Park](https://www.expedia.ca/Discovery-Island-Water-Park-Greenville.d553248621532656705.Vacation-Attraction) - [Frankie's Fun Park](https://www.expedia.ca/Frankies-Fun-Park-Greenville.d553248621532656780.Vacation-Attraction) - [Mauldin Vacations](https://www.expedia.ca/Mauldin.d183944.Destination-Travel-Guides) - [Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Prisma-Health-Greenville-Memorial-Hospital-Greenville.d553248635941390934.Vacation-Attraction) - [Terrace Shopping Center](https://www.expedia.ca/Terrace-Shopping-Center-Greenville.d553248621563220413.Vacation-Attraction) - [Car rentals near Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Car-Rentals-In-Prisma-Health-Greenville-Memorial-Hospital.d553248635941390934.Car-Rental-Guide) - [Book Family Hotels in Upstate South Carolina on Expedia.com](https://www.expedia.com/Upstate-South-Carolina-Hotels-Family-Hotel.0-0-d6057939-tFamilyHotel.Travel-Guide-Filter-Hotels)