Title: Book the Best Upstate South Carolina FAMILY FRIENDLY Hotels from CA $111 - Kid-Friendly Hotels in Upstate South Carolina, SC | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides) ![Greenville - Spartanburg featuring mountains, views and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Family Hotels in Upstate South Carolina, SC from CA $111 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Family Hotels Tonight [Sep 30 - Oct 1](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-09-30&endDate=2025-10-01&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 1 - Oct 2](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-01&endDate=2025-10-02&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-03&endDate=2025-10-05&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-10&endDate=2025-10-12&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Upstate South Carolina Family Hotels ![Exterior](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/62c16e21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b3d797da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/9895027f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton Greenville Downtown Riverplace Greenville Downtown 9.2/10 Wonderful (1023) "Very enjoyable location and hospitality. " CA $300 CA $329 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/800/708/c6283d85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/800/708/4bfc6efb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/800/708/338fc74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/800/708/2fe691fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Greenville Airport Inn Greenville 7.8/10 Good (1023) "Enjoyed my stay. Very clean and quiet stay. " CA $100 CA $111 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Greenville-Hotels-Best-Western-Greenville-Airport-Inn.h708.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b840578e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/8238721d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/96a62179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites Greenville Golf Resort & Conference Center Greenville 8.8/10 Excellent (1031) "Will definitely stay again " CA $166 CA $188 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/790000/787700/787656/5410999b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/790000/787700/787656/37ca340e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/790000/787700/787656/1a083d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/790000/787700/787656/ea246e43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Anderson, SC Anderson 8.4/10 Very good (1006) "It was a nice place." CA $146 CA $162 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Anderson-Hotels-Country-Inn-Suites-By-Radisson.h787656.Hotel-Information) ![Hypo-allergenic bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/w3840h2556x0y3-09ad394d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/w3837h2555x3y3-38c4ce41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/6e5678e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Greenville/Haywood Greenville 7.8/10 Good (1013) "great hotel" CA $145 CA $164 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![Seasonal outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/25000/24994/6e5638cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Bed, Nonsmoking, Upgrade](https://images.trvl-media.com/lodging/1000000/30000/25000/24994/5b521060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25000/24994/4075aacd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/30000/25000/24994/da37437a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Greenville - Haywood Mall Greenville 8.0/10 Very good (1006) "Great location! " CA $118 CA $134 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Greenville-Hotels-Comfort-Inn-Greenville-Haywood-Mall.h24994.Hotel-Information) ![Coffee service](https://images.trvl-media.com/lodging/1000000/160000/159200/159200/dbd51674.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/160000/159200/159200/d18b533c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/160000/159200/159200/33bcaf63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/160000/159200/159200/102ba516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Anderson-Clemson Anderson 8.4/10 Very good (1009) "Clean and friendly staff" CA $155 CA $172 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Anderson-Hotels-Comfort-Suites-Anderson-Clemson.h159200.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/19000000/18770000/18765300/18765211/8d1a7f3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/19000000/18770000/18765300/18765211/5c2ecfdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, books](https://images.trvl-media.com/lodging/19000000/18770000/18765300/18765211/930bce4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/19000000/18770000/18765300/18765211/01db0d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Relax on the shore of Lake Hartwell in our Fair Play retreat Fair Play 9.8/10 Exceptional (234) "The hosts were very responsive and accommodating. Very comfortable stay. Thank you!" [](https://www.expedia.ca/Anderson-Hotels-Charming-Secluded.h18765211.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/70000/67500/67445/2183f59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 King Bed with Sofa bed, Non Smoking | Living area](https://images.trvl-media.com/lodging/1000000/70000/67500/67445/e799826e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/70000/67500/67445/ff4774c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, pillowtop beds, in-room safe, individually furnished](https://images.trvl-media.com/lodging/1000000/70000/67500/67445/29c7f0ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Greer - Greenville Greer 8.6/10 Excellent (686) "Staff was friendly, was convenient to where we needed to go, lots to eat in the area" CA $143 CA $156 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greer-Hotels-Comfort-Inn-Suites-Greer-Greenville.h67445.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1980000/1973100/1973047/d634c8dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1980000/1973100/1973047/2bbdf0b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1980000/1973100/1973047/4743fcab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1980000/1973100/1973047/6346dbb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Greenville Greenville 9.0/10 Wonderful (381) "Great area if coming in from out of town. Shopping, restaurants, etc right there." CA $216 CA $245 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville.h1973047.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-14&endDate=2025-10-15®ionId=6057939&adults=2&travelerType=family_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Upstate South Carolina Hotel Reviews ![Hampton Inn & Suites Greenville Airport, SC](//images.trvl-media.com/lodging/12000000/11920000/11919200/11919192/de1bb5e2_y.jpg) ### Hampton Inn & Suites Greenville Airport, SC 10/10 Excellent "Check in was quick and easy, and the entire place was clean and tidy. The bed was very comfortable." [](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Airport.h11919192.Hotel-Information) ![Drury Inn & Suites Greenville](//images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Very Clean and staff was very polite." [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Hyatt Regency Greenville](//images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "Nice easy walk to bon seCour center" [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Great VALUE and great room. " [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](//images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Highly recommended Really good value for money " [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](//images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Golf Clean rooms Staff was awesome Beautiful property " [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](//images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent " Dry nice" [](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Hilton Greenville](//images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Loved everything about the Hilton! " [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](//images.trvl-media.com/lodging/1000000/10000/1400/1379/91409d5a_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 10/10 Excellent "Every thing just needs microwave in the room " [](https://expedia.ca/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Hotels with a Pool in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotel-With-Pool.0-0-d242-tHotelwithPool.Hotel-Filter-Destinations) - [Hotels with Balconies in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Balconies.0-0-d242-tHotelswithBalconies.Hotel-Filter-Destinations) - [Hotels with Free Airport Shuttle in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Free-Airport-Shuttle.0-0-d242-tHotelswithFreeAirportShuttle.Hotel-Filter-Destinations) - 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[Hotels near Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Prisma-Health-Greenville-Memorial-Hospital-Hotels.0-l553248635941390934-0.Travel-Guide-Filter-Hotels) - [Hotels near Shriners Hospitals for Children Greenville](https://www.expedia.ca/Shriners-Hospitals-For-Children-Greenville-Hotels.0-l704436698448793600-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Boutique-Hotel.0-0-d6239-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Cheap-Hotels.0-0-d6239-tCheapHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Golf-Hotel.0-0-d6239-tGolfHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Luxury-Hotel.0-0-d6239-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Pet-Friendly-Hotel.0-0-d6239-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Spa-Hotel.0-0-d6239-tSpaHotel.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Wedding-Hotels.0-0-d6239-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Flights from Donaldson Center](https://www.expedia.ca/lp/airports/gdc/flights-from-donaldson-center-airport) - [Flights from Greenville Downtown](https://www.expedia.ca/lp/airports/gmu/flights-from-greenville-downtown-airport) - [Flights from Mauldin](https://www.expedia.ca/lp/flights/183944/flights-from-mauldin) - [Flights from Anderson (AND) to Greenville (GDC)](https://www.expedia.ca/lp/flights/and/gdc/anderson-to-greenville) - [Flights from Anderson (AND) to Greenville (GMU)](https://www.expedia.ca/lp/flights/and/gmu/anderson-to-greenville) - [Flights from Atlanta (ATL) to Greenville (GMU)](https://www.expedia.ca/lp/flights/atl/gmu/atlanta-to-greenville) - [Flights from Asheville (AVL) to Greenville (GDC)](https://www.expedia.ca/lp/flights/avl/gdc/asheville-to-greenville) - 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Airport (EWR) to Greenville (GDC)](https://www.expedia.ca/lp/flights/ewr/gdc/newark-liberty-intl-airport-to-greenville) - [Flights from Rome (FCO) to Greenville (GDC)](https://www.expedia.ca/lp/flights/fco/gdc/rome-to-greenville) - [Flights from Gatlinburg (GKT) to Greenville (GDC)](https://www.expedia.ca/lp/flights/gkt/gdc/gatlinburg-to-greenville) - [Flights from Gatlinburg (GKT) to Greenville (GMU)](https://www.expedia.ca/lp/flights/gkt/gmu/gatlinburg-to-greenville) - [Flights from Greenwood (GRD) to Greenville (GDC)](https://www.expedia.ca/lp/flights/grd/gdc/greenwood-to-greenville) - [Flights from Greenwood (GRD) to Greenville (GMU)](https://www.expedia.ca/lp/flights/grd/gmu/greenwood-to-greenville) - [Flights from Islip (ISP) to Greenville (GMU)](https://www.expedia.ca/lp/flights/isp/gmu/islip-to-greenville) - [Flights from Jacksonville (JAX) to Greenville (GMU)](https://www.expedia.ca/lp/flights/jax/gmu/jacksonville-to-greenville) - [Flights from New York (JFK) to Greenville (GDC)](https://www.expedia.ca/lp/flights/jfk/gdc/new-york-to-greenville) - 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[Frankie's Fun Park](https://www.expedia.ca/Frankies-Fun-Park-Greenville.d553248621532656780.Vacation-Attraction) - [Mauldin Vacations](https://www.expedia.ca/Mauldin.d183944.Destination-Travel-Guides) - [Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Prisma-Health-Greenville-Memorial-Hospital-Greenville.d553248635941390934.Vacation-Attraction) - [Terrace Shopping Center](https://www.expedia.ca/Terrace-Shopping-Center-Greenville.d553248621563220413.Vacation-Attraction) - [Car rentals near Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Car-Rentals-In-Prisma-Health-Greenville-Memorial-Hospital.d553248635941390934.Car-Rental-Guide) - [Book Family Hotels in Upstate South Carolina on Expedia.com](https://www.expedia.com/Upstate-South-Carolina-Hotels-Family-Hotel.0-0-d6057939-tFamilyHotel.Travel-Guide-Filter-Hotels)