Title: Book the Best BUSINESS Hotels in Upstate South Carolina in 2025 | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides) ![Greenville - Spartanburg featuring mountains, views and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Upstate South Carolina, SC ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Business Hotels Tonight [Oct 6 - Oct 7](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-06&endDate=2025-10-07&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 7 - Oct 8](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-07&endDate=2025-10-08&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-10&endDate=2025-10-12&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-10-17&endDate=2025-10-19&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Upstate South Carolina Business Hotels ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/7925adb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining tables](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/406b11ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/69b6f44b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/2091752b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Woodspring Suites Greenville Airport Greenville 8.6/10 Excellent (228) "Great place to stay will definitely book here again " CA $110 CA $121 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/d223eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/a9edd66e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/65f927f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Microwave (with Sofabed)](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/188dc421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Seneca-Clemson Seneca 8.4/10 Very good (620) "Convenient for Clemson visits." CA $125 CA $137 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/9fe06894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/cc35e730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/a9307e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Seneca Clemson Univ Area Seneca 9.4/10 Exceptional (194) "Nice hotel by the lake" CA $167 CA $184 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/49a2146a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/05d8cd44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 9:00 PM, free cabanas](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/8fa71ed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch, dinner, brunch served; American cuisine ](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/199642a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson University's James F. Martin Inn Clemson 9.6/10 Exceptional (940) "Amazing place to stay. " CA $208 CA $231 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/43000000/42640000/42633300/42633276/e0ede3d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/43000000/42640000/42633300/42633276/c2b1f476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/43000000/42640000/42633300/42633276/7f93b55c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/43000000/42640000/42633300/42633276/0de5cb8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Greenville - Taylors by IHG Greenville 9.2/10 Wonderful (637) "Really really nice hotel, well worth their reasonable rates. Looks brand new in the room!" CA $172 CA $189 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Holiday-Inn-Express-And-Suites-Greenville-Taylors.h42633276.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/fd542db9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/c83ed6f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/a7c81686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/9b9d3bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Travelers Rest Greenville Travelers Rest 7.6/10 Good (1004) "Staff was very accommodating " CA $135 CA $149 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Travelers-Rest-Hotels-Best-Western-Travelers-Rest-Greenville.h105540.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/34000000/33410000/33403500/33403422/6940a631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/34000000/33410000/33403500/33403422/ac5828ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/34000000/33410000/33403500/33403422/00b3b1b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/34000000/33410000/33403500/33403422/790f74ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Greenville Woodruff Road Greenville 9.2/10 Wonderful (260) "Great hotel" CA $141 CA $168 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Tru-By-Hilton-Greenville-Woodruff-Road.h33403422.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/fe5b957d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6e7a607b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/164da543.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Greenville Greenville 9.6/10 Exceptional (1004) "Kind staff and easy check in." CA $160 CA $176 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/282fab11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2557x3y4-050d425f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Clemson Hotel & Conference Center Clemson 8.2/10 Very good (1007) "Excellent stay & so helpful!" CA $117 CA $130 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/f93d0c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/14e3230b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/452fcf9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/94f8bd4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Anderson/Clemson Anderson 8.2/10 Very good (1001) "Great stay" CA $103 CA $115 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-20&endDate=2025-10-21®ionId=6057939&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Upstate South Carolina Hotel Reviews ![Hampton Inn & Suites Greenville Airport, SC](//images.trvl-media.com/lodging/12000000/11920000/11919200/11919192/de1bb5e2_y.jpg) ### Hampton Inn & Suites Greenville Airport, SC 10/10 Excellent "Front desk staff helpful and friendly." [](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Airport.h11919192.Hotel-Information) ![Drury Inn & Suites Greenville](//images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "I loved my stay here! The rooms are spotless, the staff are so warm and welcoming, and the location is awesome with lots of restaurants and shops nearby. The price is such a great deal—you get free breakfast, dinner, AND three drinks every night! Can’t recommend it enough!" [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](//images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "Good breakfast. Friendly staff. Great location. " [](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Clean room, nice staff, and convenient location. " [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Embassy Suites by Hilton Greenville Downtown Riverplace](//images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89_y.jpg) ### Embassy Suites by Hilton Greenville Downtown Riverplace 10/10 Excellent "Perfect spot! Shopping, food, drinks, amazing. Great comfort and service. " [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](//images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Always very good stay. They have some construction going on with the elevator though " [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](//images.trvl-media.com/lodging/1000000/10000/1400/1379/91409d5a_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 10/10 Excellent "Yes great places" [](https://expedia.ca/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ![Hilton Greenville](//images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Very nice " [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Hyatt Regency Greenville](//images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "The Hyatt was in the center of eveything that is going on. Staff was very kind and very helpfull and so many good restaurants in walking distance and well night life. Highly recommend staying at the Hyatt Regency!" [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Upstate South Carolina cost? > You can expect to pay between and per night for business-friendly hotels in Upstate South Carolina. Terrific deals on stays that are suitable for work-related travellers are a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### What are the best business-friendly hotels in Upstate South Carolina? > That depends on your destination in Upstate South Carolina. Lots of business travellers to Greenville choose [Homewood Suites by Hilton Greenville Downtown](https://www.expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville-Downtown.h29050020.Hotel-Information). This 3-stars property has a barbecue grill and a swimming pool. [SpringHill Suites by Marriott Greenville Downtown](https://www.expedia.ca/Greenville-Hotels-SpringHill-Suites-By-Marriott-Greenville-Downtown.h31718906.Hotel-Information) is another excellent option if you're arranging a meeting or working remotely in Greenville. A swimming pool and a barbecue grill are some of the useful amenities at this 2.5-stars retreat. You can choose from multiple business-friendly hotels in Upstate South Carolina that have a total average guest review rating of . ### How many business-friendly hotels are there in Upstate South Carolina? > When your next meeting or conference takes you someplace in Upstate South Carolina, you'll have business-friendly hotels to choose from. ### What are the best cheap business-friendly hotels in Upstate South Carolina? > That depends on which corner of Upstate South Carolina work is taking you. If you're headed to Greenville, [SpringHill Suites by Marriott Greenville Downtown](https://www.expedia.ca/Greenville-Hotels-SpringHill-Suites-By-Marriott-Greenville-Downtown.h31718906.Hotel-Information) combines affordability with business-friendly amenities. A terrace and a barbecue grill are a couple of its many conveniences. On your way to Spartanburg? Look up [Tru by Hilton Spartanburg](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Tru-By-Hilton-Spartanburg.h48251408.Hotel-Information). WiFi and a playground help make this cheaper property a favourite with corporate visitors. Business-friendly hotels start at just per night, so your next work trip doesn't have to stretch your finances. There are loads of fun and free things to do wherever you're headed in Upstate South Carolina. If business is taking you to Greenville, try to find time to swing by [Greenville County Museum of Art](https://www.expedia.ca/Greenville-County-Museum-Of-Art-Greenville-Downtown.d6082717.Vacation-Attraction). You can also go sightseeing without spending a dime in Spartanburg. [Spartanburg Regional Hospital](https://www.expedia.ca/Spartanburg-Regional-Hospital-Spartanburg.d6245689.Vacation-Attraction) is one of the most popular free attractions here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### What are the top business-friendly motels in Upstate South Carolina? > Expedia's business-friendly motels in Upstate South Carolina come with amenities that are the ideal mix of work and play. One of our best options is [Urban Boutique Hotel, BW Signature Collection](https://www.expedia.ca/Greenville-Hotels-Urban-Boutique-Hotel.h24334.Hotel-Information) in Greenville. Located around 3 kilometres northeast of the downtown area, WiFi and front desk services are the start of its many conveniences. Another stay that appeals to corporate travellers is [Days Inn by Wyndham Greenville](https://www.expedia.ca/Greenville-Hotels-Days-Inn-By-Wyndham-Greenville.h22276.Hotel-Information). It's approximately 8 kilometres east of the centre of Greenville and features a swimming pool, front desk services and more.There are a ton of things to keep you entertained when you're not hard at work in Greenville. [The Peace Centre](https://www.expedia.ca/The-Peace-Center-Greenville-Downtown.d6082705.Vacation-Attraction) and [Frankie's Fun Park](https://www.expedia.ca/Frankies-Fun-Park-Greenville.d553248621532656780.Vacation-Attraction) should be on your sightseeing checklist. ### Are there any family-friendly hotels in Upstate South Carolina that are also business friendly? > You'll discover some terrific family-friendly hotels that are also business friendly in Upstate South Carolina. If you're on your way to Greenville, take a look at [SpringHill Suites by Marriott Greenville Downtown](https://www.expedia.ca/Greenville-Hotels-SpringHill-Suites-By-Marriott-Greenville-Downtown.h31718906.Hotel-Information). It comes with useful amenities like complimentary breakfast and WiFi and has a 2.5-stars rating. Another option to consider is [Hampton Inn & Suites Greenville-Downtown-RiverPlace](https://www.expedia.ca/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Downtown-RiverPlace.h1460359.Hotel-Information). This 2.5-stars stay in Greenville is perfect for both leisure and business travellers and offers complimentary breakfast, room service and more. Greenville offers loads of family-friendly attractions when you're ready to discover the sights. [Frankie's Fun Park](https://www.expedia.ca/Frankies-Fun-Park-Greenville.d553248621532656780.Vacation-Attraction) and [Greenville Zoo](https://www.expedia.ca/Greenville-Zoo-Greenville-Downtown.d6082709.Vacation-Attraction) will keep your crew entertained. ### Are there any 5-star business-friendly hotels in Upstate South Carolina? > In Upstate South Carolina, 5-star business-friendly hotels are difficult to come by. However, there are some 4-star properties that cater to corporate travellers. If you're making tracks to Greenville for work, base yourself at [The Westin Poinsett Greenville](https://www.expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information). It comes with handy amenities including pillow top mattresses and room service. Or, put your laptop down and feet up at [Greenville Marriott](https://www.expedia.ca/Greenville-Hotels-Greenville-Marriott.h17483.Hotel-Information), also in Greenville. Take advantage of its conveniences including a swimming pool and pillow top mattresses. ### Why book your business-friendly hotel in Upstate South Carolina with Expedia? > We're here to help you find a suitable business-friendly hotel when work takes you on the road. From free parking and WiFi to gyms and on-site restaurants, our properties have the things you'll need to get the job done. ### How can I find cheap business-friendly hotels in Upstate South Carolina? > When work takes you to Upstate South Carolina, our "business friendly" filter will help you find the right hotel. From WiFi to workspaces and meeting rooms, they come with the amenities you need for a productive and comfortable stay. You can also narrow your search by your preferred star rating and budget to see the most affordable properties. ### What is there to do in Upstate South Carolina near my business-friendly hotel? > The most important travel accessory for your Upstate South Carolina business journey is a good itinerary for your free time! [The Peace Centre](https://www.expedia.ca/The-Peace-Center-Greenville-Downtown.d6082705.Vacation-Attraction), [Greenville Zoo](https://www.expedia.ca/Greenville-Zoo-Greenville-Downtown.d6082709.Vacation-Attraction) and [The Children's Museum of the Upstate](https://www.expedia.ca/The-Childrens-Museum-Of-The-Upstate-Greenville-Downtown.d553248621532656777.Vacation-Attraction) are some of the well-known sights if you're staying in Greenville. Spartanburg also has plenty of superb attractions, such as [Spartanburg Memorial Auditorium](https://www.expedia.ca/Spartanburg-Memorial-Auditorium-Spartanburg.d6245714.Vacation-Attraction), [Spartanburg Regional History Museum](https://www.expedia.ca/Spartanburg-Regional-History-Museum-Spartanburg.d553248621532656805.Vacation-Attraction) and [Chapman Cultural Centre](https://www.expedia.ca/Chapman-Cultural-Center-Spartanburg.d6278987.Vacation-Attraction). ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Hotels with a Pool in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotel-With-Pool.0-0-d242-tHotelwithPool.Hotel-Filter-Destinations) - [Hotels with Balconies in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Balconies.0-0-d242-tHotelswithBalconies.Hotel-Filter-Destinations) - [Hotels with Free Airport Shuttle in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Free-Airport-Shuttle.0-0-d242-tHotelswithFreeAirportShuttle.Hotel-Filter-Destinations) - 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