Title: Book the Best Upstate South Carolina Adults Only Resorts & Hotels in 2025 | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides) ![The view from Caesars Head after a storm](https://images.trvl-media.com/place/553248621532656715/293b23c7-6024-49ab-80cb-4ee292c1b5a3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michelle Hendrix # Find Adults Only Resorts & Hotels in Upstate South Carolina, SC - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Adults Only Resorts & Hotels Tonight [Nov 20 - Nov 21](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-11-20&endDate=2025-11-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [Nov 21 - Nov 22](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-11-21&endDate=2025-11-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) This weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) ## Top Upstate South Carolina Adults Only Resorts & Hotels No exact matches found, but these alternatives could be just right ## Recommended hotels in Upstate South Carolina ![Outdoor pool](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/fbbe5f39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/56ecee45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/799eeb33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/d45e119a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Greer Greenville, SC Greer 9.6/10 Exceptional (402) "Nice hotel, convenient location with helpful staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $194 CA $212 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/Greer-Hotels-Hampton-Inn-Greer-Greenville.h68975422.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/88b33cc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/704d2b55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/8e2d308e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/a74bbe34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Greenville Downtown Greenville Downtown 9.6/10 Exceptional (1005) "Great room, great staff, excellent breakfast, super clean. perfect location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arnold CA $127 CA $144 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville-Downtown.h29050020.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/f59bfe6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/498d5401.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/586dbae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/36a85341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Greenville Woodruff Road Greenville 9.4/10 Exceptional (1006) "The hotel was excellent m." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brittiany CA $143 CA $157 total includes taxes & fees Nov 26 - Nov 27 [](https://www.expedia.ca/Greenville-Hotels-DoubleTree-By-Hilton-Greenville-Woodruff-Road.h50828647.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/589dc000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/f5139881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/d8b2892f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, desk, blackout drapes](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/bd03801f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Gaffney by IHG Gaffney 8.6/10 Excellent (407) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy CA $103 CA $113 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information) ![Standard Cabin, Courtyard View](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/344b1497.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, Multiple Beds, Courtyard View](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/b3efbc78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/ddc562e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 King Bed with Sofa bed, Courtyard View | Private kitchen](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/7f4f7187.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carolina Camp Cedar Pickens CA $138 CA $278 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/60389240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/70604dbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/e417f297.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/a3e9e5b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Anderson/ Alliance Business Park Anderson 9.2/10 Wonderful (790) "Very comfortable stay convenient to Greenville Spartanburg Airport." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rick CA $144 CA $160 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Anderson-North.h3629858.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/d191b963.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Resort Studio with Kitchen and Two Queen | Private kitchen](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/70e13494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/01158bad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson Seneca 9.0/10 Wonderful (1005) "Overall great stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel CA $152 CA $189 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/10f1fcf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/2bb8d81a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/83732283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible (Hearing, Roll-In Shower)](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/d36e662a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Seneca Clemson Seneca 9.2/10 Wonderful (781) "Clean room, staff was great, will always stay at this hotel in Clemson. Best place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gretchen CA $133 CA $146 total includes taxes & fees Dec 12 - Dec 13 [](https://www.expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/56d69457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Custom King Full](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/179daec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/cbe6a617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e408dd97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson Clemson 9.6/10 Exceptional (551) "location is amazing! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) colleen [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/01b325b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/5e9a8e7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/7c5ccfc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Greenville Downtown Greenville Downtown 9.0/10 Wonderful (1001) "Perfect place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie CA $176 CA $194 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-04&endDate=2025-12-05®ionId=6057939&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Limited-time deals: save up to 50% on select hotels [Book now](https://expedia.ca/deals?rfrr=AFFINITY_BF_PROMO_6057939) ## Top Upstate South Carolina Hotel Reviews ## Frequently asked questions ### Are there any adult-only all-inclusive resorts in Upstate South Carolina? > Unfortunately, there aren't any adult-only all-inclusive resorts or hotels in Upstate South Carolina. But, if you're going away with your other half and seeking a romantic stay, we recommend [Pettigru Place Bed And Breakfast](https://www.expedia.ca/Greenville-Hotels-Pettigru-Place-Bed-Breakfast.h663745.Hotel-Information). Located in Greenville, it features premium bedding and dining romance packages. Another choice is [Homewood Suites by Hilton Greenville Downtown](https://www.expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville-Downtown.h29050020.Hotel-Information). Also in Greenville, it offers a fireplace in the lobby and a terrace. ### What is there to do in Upstate South Carolina near my adults-only hotel? > You'll find countless ways to spend your time in Upstate South Carolina. If you're headed to Greenville, drop by Greenville Zoo, The Children's Museum of the Upstate and Shoeless Joe Jackson Museum. Packing your bags for Spartanburg? Spartanburg Regional History Museum, Wofford College and Converse College are popular sights here. ### How can I find cheap adults-only hotels in Upstate South Carolina? > Expedia can help you look for cheap adults-only hotels in Upstate South Carolina. Simply use the filter tool to select amenities, star rating and budget to refine your search results and lock in the best child-free stay in just a few keystrokes. ### From what age can you stay in an adult-only hotel in Upstate South Carolina? > It varies, but generally guests must be 16, 18 or 21. Rules may be different from one property to the next, so be sure to check the conditions of the adult-only hotel or resort in Upstate South Carolina that catches your eye. Whether you're organizing a birthday party with your friends or a romantic escape for two, Expedia's adult-only getaways offer nothing but kid-free, stress-free good times. ### Are all adult-only resorts all-inclusive in Upstate South Carolina? > If you only plan to stay at a hotel or resort where most of what you need is included in the cost of the room, try our "all-inclusive" filter. This will show you a list of adult-only all-inclusive properties in Upstate South Carolina that generally include the room, food and drinks, a selection of on-site activities and great entertainment. Select the hotel you have your eye on to find out what you get for your money. ### Why book your adults-only hotel in Upstate South Carolina with Expedia? > Offering affordable prices and an impressive range of properties, Expedia makes it a cinch to find the ideal adults-only hotel in Upstate South Carolina. Splurge on a luxury resort or use our handy search filters to locate a wallet-friendly stay. From the moment you click on your travel dates to when you lock in a place that ticks all your boxes, Expedia is there every step of the way. ### When is the best time to stay at an adult-only all-inclusive resort in Upstate South Carolina? > The best time to stay at an adult-only all-inclusive hotel or resort in Upstate South Carolina can depend on a few things, the first one being the weather. Also consider whether you want to experience the buzz of peak season, when demand for hotels and flights is high, or the low season, when things are a bit less hectic. Take into account your budget and personal travel style before locking in your dream adult-only adventure that offers the whole shebang! ### Can I cancel or change my adult-only resort booking? > You sure can. Depending on the type of hotel booking you made and how close you are to your check-in date, you may not be charged a fee. Rules can differ from one adult-only hotel or resort to the next, so check your itinerary or head to Expedia's [Trips portal](https://www.expedia.ca/trips) for information. If you're hoping to make your trip to Upstate South Carolina as worry-free as possible, select adult-only properties that allow full refunds. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Hotels with a Pool in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotel-With-Pool.0-0-d242-tHotelwithPool.Hotel-Filter-Destinations) - [Hotels with Balconies in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Balconies.0-0-d242-tHotelswithBalconies.Hotel-Filter-Destinations) - [Hotels with Free Airport Shuttle in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Free-Airport-Shuttle.0-0-d242-tHotelswithFreeAirportShuttle.Hotel-Filter-Destinations) - [Hotels with Free Breakfast in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Free-Breakfast.0-0-d242-tHotelswithFreeBreakfast.Hotel-Filter-Destinations) - [Hotels with Free Parking in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Free-Parking.0-0-d242-tHotelswithFreeParking.Hotel-Filter-Destinations) - 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[Waterpark Hotels in Greenville Downtown](https://www.expedia.ca/Greenville-Downtown-Greenville-Hotels-Waterpark-Hotels.0-n6348006-0-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Hotels near Haywood Mall](https://www.expedia.ca/Haywood-Mall-Hotels.0-l6130785-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Mauldin](https://www.expedia.ca/Mauldin-Hotels-Cheap-Hotels.0-0-d183944-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Mauldin](https://www.expedia.ca/Mauldin-Hotels-Luxury-Hotel.0-0-d183944-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Mauldin](https://www.expedia.ca/Mauldin-Hotels-Pet-Friendly-Hotel.0-0-d183944-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Mauldin](https://www.expedia.ca/Mauldin-Hotels-Spa-Hotel.0-0-d183944-tSpaHotel.Travel-Guide-Filter-Hotels) - [Mauldin Hotels](https://www.expedia.ca/Mauldin-Hotels.d183944.Travel-Guide-Hotels) - [Hotels near Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Prisma-Health-Greenville-Memorial-Hospital-Hotels.0-l553248635941390934-0.Travel-Guide-Filter-Hotels) - [Hotels near Shriners Hospitals for Children Greenville](https://www.expedia.ca/Shriners-Hospitals-For-Children-Greenville-Hotels.0-l704436698448793600-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Boutique-Hotel.0-0-d6239-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Cheap-Hotels.0-0-d6239-tCheapHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Golf-Hotel.0-0-d6239-tGolfHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Luxury-Hotel.0-0-d6239-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Pet-Friendly-Hotel.0-0-d6239-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Spa-Hotel.0-0-d6239-tSpaHotel.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Simpsonville](https://www.expedia.ca/Simpsonville-Hotels-Wedding-Hotels.0-0-d6239-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Flights from Donaldson Center](https://www.expedia.ca/lp/airports/gdc/flights-from-donaldson-center-airport) - [Flights from Greenville Downtown](https://www.expedia.ca/lp/airports/gmu/flights-from-greenville-downtown-airport) - [Flights from Mauldin](https://www.expedia.ca/lp/flights/183944/flights-from-mauldin) - [Flights from Anderson (AND) to Greenville (GDC)](https://www.expedia.ca/lp/flights/and/gdc/anderson-to-greenville) - [Flights from Anderson (AND) to Greenville (GMU)](https://www.expedia.ca/lp/flights/and/gmu/anderson-to-greenville) - [Flights from Atlanta (ATL) to Greenville (GMU)](https://www.expedia.ca/lp/flights/atl/gmu/atlanta-to-greenville) - [Flights from Asheville (AVL) to Greenville (GDC)](https://www.expedia.ca/lp/flights/avl/gdc/asheville-to-greenville) - [Flights from Birmingham (BHM) to Greenville (GMU)](https://www.expedia.ca/lp/flights/bhm/gmu/birmingham-to-greenville) - 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Airport (EWR) to Greenville (GDC)](https://www.expedia.ca/lp/flights/ewr/gdc/newark-liberty-intl-airport-to-greenville) - [Flights from Rome (FCO) to Greenville (GDC)](https://www.expedia.ca/lp/flights/fco/gdc/rome-to-greenville) - [Flights from Gatlinburg (GKT) to Greenville (GDC)](https://www.expedia.ca/lp/flights/gkt/gdc/gatlinburg-to-greenville) - [Flights from Gatlinburg (GKT) to Greenville (GMU)](https://www.expedia.ca/lp/flights/gkt/gmu/gatlinburg-to-greenville) - [Flights from Greenwood (GRD) to Greenville (GDC)](https://www.expedia.ca/lp/flights/grd/gdc/greenwood-to-greenville) - [Flights from Greenwood (GRD) to Greenville (GMU)](https://www.expedia.ca/lp/flights/grd/gmu/greenwood-to-greenville) - [Flights from Huntsville (HSV) to Greenville (GMU)](https://www.expedia.ca/lp/flights/hsv/gmu/huntsville-to-greenville) - [Flights from Islip (ISP) to Greenville (GMU)](https://www.expedia.ca/lp/flights/isp/gmu/islip-to-greenville) - [Flights from Jacksonville (JAX) to Greenville (GMU)](https://www.expedia.ca/lp/flights/jax/gmu/jacksonville-to-greenville) - [Flights from New York (JFK) to Greenville (GDC)](https://www.expedia.ca/lp/flights/jfk/gdc/new-york-to-greenville) - [Flights from New York (JFK) to Greenville (GMU)](https://www.expedia.ca/lp/flights/jfk/gmu/new-york-to-greenville) - [Flights from Las Vegas (LAS) to Greenville (GDC)](https://www.expedia.ca/lp/flights/las/gdc/las-vegas-to-greenville) - [Flights from Pickens (LQK) to Greenville (GDC)](https://www.expedia.ca/lp/flights/lqk/gdc/pickens-to-greenville) - [Flights from Orlando (MCO) to Greenville (GDC)](https://www.expedia.ca/lp/flights/mco/gdc/orlando-to-greenville) - [Flights from Manteo (MEO) to Greenville (GMU)](https://www.expedia.ca/lp/flights/meo/gmu/manteo-to-greenville) - [Flights from Miami (MIA) to Greenville (GDC)](https://www.expedia.ca/lp/flights/mia/gdc/miami-to-greenville) - [Flights from Miami (MIA) to Greenville (GMU)](https://www.expedia.ca/lp/flights/mia/gmu/miami-to-greenville) - [Flights from New Orleans (MSY) to Greenville (GMU)](https://www.expedia.ca/lp/flights/msy/gmu/new-orleans-to-greenville) - [Flights from Chicago (ORD) to Greenville (GDC)](https://www.expedia.ca/lp/flights/ord/gdc/chicago-to-greenville) - [Flights from Norfolk (ORF) to Greenville (GMU)](https://www.expedia.ca/lp/flights/orf/gmu/norfolk-to-greenville) - [Flights from West Palm Beach (PBI) to Greenville (GMU)](https://www.expedia.ca/lp/flights/pbi/gmu/west-palm-beach-to-greenville) - [Flights from Philadelphia (PHL) to Greenville (GMU)](https://www.expedia.ca/lp/flights/phl/gmu/philadelphia-to-greenville) - [Flights from Raleigh (RDU) to Greenville (GMU)](https://www.expedia.ca/lp/flights/rdu/gmu/raleigh-to-greenville) - [Flights from Rocky Mount (RWI) to Greenville (GMU)](https://www.expedia.ca/lp/flights/rwi/gmu/rocky-mount-to-greenville) - [Flights from San Antonio (SAT) to Greenville (GDC)](https://www.expedia.ca/lp/flights/sat/gdc/san-antonio-to-greenville) - [Flights from Savannah (SAV) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sav/gmu/savannah-to-greenville) - [Flights from Schenectady (SCH) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sch/gmu/schenectady-to-greenville) - [Flights from Sanford (SFM) to Greenville (GMU)](https://www.expedia.ca/lp/flights/sfm/gmu/sanford-to-greenville) - [Flights from Newburgh (SWF) to Greenville (GMU)](https://www.expedia.ca/lp/flights/swf/gmu/newburgh-to-greenville) - [Flights from Montreal (YUL) to Greenville (GMU)](https://www.expedia.ca/lp/flights/yul/gmu/montreal-to-greenville) - [Flights from Vancouver (YVR) to Greenville (GMU)](https://www.expedia.ca/lp/flights/yvr/gmu/vancouver-to-greenville) - [Flights from Toronto (YYZ) to Greenville (GDC)](https://www.expedia.ca/lp/flights/yyz/gdc/toronto-to-greenville) - [Flights from Toronto (YYZ) to Greenville (GMU)](https://www.expedia.ca/lp/flights/yyz/gmu/toronto-to-greenville) - [7th Inning Splash Waterpark](https://www.expedia.ca/7th-Inning-Splash-Waterpark-Piedmont.d553248621532656702.Vacation-Attraction) - [Central Vacations](https://www.expedia.ca/Central.d10503.Destination-Travel-Guides) - [Discovery Island Water Park](https://www.expedia.ca/Discovery-Island-Water-Park-Greenville.d553248621532656705.Vacation-Attraction) - [Frankie's Fun Park](https://www.expedia.ca/Frankies-Fun-Park-Greenville.d553248621532656780.Vacation-Attraction) - [Mauldin Vacations](https://www.expedia.ca/Mauldin.d183944.Destination-Travel-Guides) - [Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Prisma-Health-Greenville-Memorial-Hospital-Greenville.d553248635941390934.Vacation-Attraction) - [Terrace Shopping Center](https://www.expedia.ca/Terrace-Shopping-Center-Greenville.d553248621563220413.Vacation-Attraction) - [Car rentals near Prisma Health Greenville Memorial Hospital](https://www.expedia.ca/Car-Rentals-In-Prisma-Health-Greenville-Memorial-Hospital.d553248635941390934.Car-Rental-Guide) - [Book Adults Only Resorts & Hotels in Upstate South Carolina on Expedia.com](https://www.expedia.com/Upstate-South-Carolina-Hotels-Adults-Only-Resorts.0-0-d6057939-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels)