Title: Book the Best University City SPA Resorts from CA $181 - Spa Hotels in University City, San Diego | Expedia.ca [University City Travel Guide](https://expedia.ca/San-Diego-University-City.dx553248635976008131)[Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[University City Car Rentals](https://expedia.ca/Car-Rentals-In-University-City.d553248635976008131.Car-Rental-Guide)[University City Vacations](https://expedia.ca/University-City.d553248635976008131.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/3073/bcda3a58-eac1-4b1b-a9c4-3578b786efd9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in University City, San Diego from CA $181 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on University City Spa Hotels Tonight [Dec 28 - Dec 29](https://www.expedia.ca/Hotel-Search?regionId=553248635976008131&startDate=2025-12-28&endDate=2025-12-29&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 29 - Dec 30](https://www.expedia.ca/Hotel-Search?regionId=553248635976008131&startDate=2025-12-29&endDate=2025-12-30&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976008131&startDate=2026-01-02&endDate=2026-01-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248635976008131&startDate=2026-01-09&endDate=2026-01-11&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for University City hotels with a spa ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/858/c5325c92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/900/858/543624c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse](https://images.trvl-media.com/lodging/1000000/10000/900/858/36c2b78d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/900/858/c6795882.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Mission Bay Spa and Marina [](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-Mission-Bay-Spa-And-Marina.h858.Hotel-Information) Mission Bay 8.4/10 Very good (1585) "Totally Recommend! Rooms are really clean and comfortable, the staff are great as well. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fernando CA $176 CA $275 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-Mission-Bay-Spa-And-Marina.h858.Hotel-Information) ![Hot stone massages, prenatal massages, sports massages, body scrubs](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/25a004df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/c2cecb91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, white sand, windsurfing, beach volleyball](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/c20f7d47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/bbcdbd6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Diego Mission Bay Resort [](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Mission-Bay-Resort.h25598.Hotel-Information) Mission Bay 8.4/10 Very good (1316) "Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Haley CA $193 CA $284 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Mission-Bay-Resort.h25598.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/d9cbfe80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/99024d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2540b7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2d82864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loews Coronado Bay Resort [](https://www.expedia.ca/Coronado-Hotels-Loews-Coronado-Bay-Resort.h25840.Hotel-Information) Silver Strand 8.8/10 Excellent (1065) "Clean room, gorgeous grounds, very friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Taryn CA $272 CA $369 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/Coronado-Hotels-Loews-Coronado-Bay-Resort.h25840.Hotel-Information) ![Body treatments, aromatherapy, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/b1fc21d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/ed2e1ba0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/2df2def5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Californian cuisine, ocean views ](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/06f19e3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton San Diego Bayfront [](https://www.expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Bayfront.h1871645.Hotel-Information) Downtown San Diego 8.6/10 Excellent (1897) "Enjoyed my stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brandon CA $160 CA $253 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Bayfront.h1871645.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/8496a8ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/9de092e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Californian cuisine, pool views ](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/8c14c190.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9700/9660/5c2bbbc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Island Palms Hotel & Marina [](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Plus-Island-Palms-Hotel-Marina.h9660.Hotel-Information) Point Loma 8.8/10 Excellent (1558) "Staff was great, easy check in and great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alysa CA $158 CA $181 total includes taxes & fees Jan 12 - Jan 13, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Plus-Island-Palms-Hotel-Marina.h9660.Hotel-Information) ![Couples treatment rooms, body treatments, hot stone massages](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/cba9a8a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/21efa256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/43ef19cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Legacy Resort Hotel & Spa [](https://www.expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) Mission Valley 9.2/10 Wonderful (2940) "Great boutique hotel!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maksim CA $196 CA $225 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![Body treatments, aromatherapy, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/2000000/1800000/1795500/1795470/46ce5fac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1800000/1795500/1795470/a316e693.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1800000/1795500/1795470/658eda87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby, free beach shuttle, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/2000000/1800000/1795500/1795470/86433ec0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Carlsbad Resort & Spa [](https://www.expedia.ca/Carlsbad-Hotels-Sheraton-Carlsbad-Resort-Spa.h1795470.Hotel-Information) Carlsbad Ranch 8.2/10 Very good (1002) "Staff were excellent. Property is beautiful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrea CA $231 CA $315 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/Carlsbad-Hotels-Sheraton-Carlsbad-Resort-Spa.h1795470.Hotel-Information) ![Premier Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/fde0003f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor banquet area](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/6257cb78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/cc4883a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Handlery Hotel [](https://www.expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) Mission Valley 8.2/10 Very good (2253) "Room and staff were excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bryant [](https://www.expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/ef17b3e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/e7aa7734.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/5d6482eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/743ac288.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pier South Resort, Autograph Collection by Marriott [](https://www.expedia.ca/Imperial-Beach-Hotels-Pier-South-Resort.h570818.Hotel-Information) Imperial Beach 8.4/10 Very good (1002) "Room was beautiful, everything about my stay was perfect." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Victoria CA $220 CA $282 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Imperial-Beach-Hotels-Pier-South-Resort.h570818.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/bc1e5add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/a9d5662a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Californian cuisine](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/7fe47de0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 outdoor pools, a heated pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/d0f041ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Paradise Point Resort & Spa [](https://www.expedia.ca/San-Diego-Hotels-Paradise-Point-Resort-Spa.h3731.Hotel-Information) Mission Bay 8.6/10 Excellent (2359) "A very unexpected surprise place for vacation! We truly enjoyed the resort, it reminds us of Hawaii! Just a great place and we highly recommend it!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ralitza CA $177 CA $276 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Paradise-Point-Resort-Spa.h3731.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-12&endDate=2026-01-13®ionId=553248635976008131&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about University City ### Top University City attractions for a relaxing vacation In the vibrant University City neighbourhood, travellers seeking hotels with spas will find a wealth of enriching experiences. Begin your journey at the stunning Barnes Foundation, where the serene gardens and exquisite art collection offer a tranquil escape. Just a short stroll away lies the renowned Philadelphia Museum of Art, perfect for art enthusiasts looking to immerse themselves in creativity before retreating to a luxurious spa treatment. For those who appreciate nature, the beautiful landscapes of the Schuylkill River Trail provide a picturesque setting for leisurely walks or invigorating bike rides. Food lovers will delight in the diverse culinary scene, from charming bistros to acclaimed restaurants, all offering delightful dining experiences that can complement a day of pampering. Lastly, the nearby University of Pennsylvania offers a rich cultural backdrop, with its historic architecture and vibrant campus atmosphere adding to the area's allure. Staying at one of the upscale hotels with spas in University City, you'll experience exceptional service tailored to your needs, luxurious amenities, and the perfect blend of relaxation and adventure, making each moment of your trip truly memorable. ## Top University City Hotel Reviews ![DoubleTree by Hilton Hotel San Diego - Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "Don't know about the bar, did not eat breakfast" [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "The staff was very friendly all throughout the resort. They checked us in at 1:30PM & upgraded our room which was a nice surprise. The s'mores after dinner at the firepits was a nice conclusion to our evening." [](https://expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Resort.h11109.Hotel-Information) ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "No complaints we are definitely going back " [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Embassy Suites by Hilton San Diego La Jolla](https://images.trvl-media.com/lodging/1000000/10000/8500/8434/49079311_y.jpg) ### Embassy Suites by Hilton San Diego La Jolla 10/10 Excellent "Great staff. Great room. Great location" [](https://expedia.ca/San-Diego-Hotels-Embassy-Suites-By-Hilton-San-Diego-La-Jolla.h8434.Hotel-Information) ![Kings Inn San Diego](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "Our stays here have always been great. That trend continues. Great services all the way around" [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Excellent " [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "Stayed here w my wife and two kids for a long weekend. The property and location are 5 star. The food and drinks are better than most resorts. Looking forward to coming back. " [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![Four Points by Sheraton San Diego](https://images.trvl-media.com/lodging/1000000/30000/23700/23651/d216d27d_y.jpg) ### Four Points by Sheraton San Diego 10/10 Excellent " Good" [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego.h23651.Hotel-Information) ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "The location is great with easy access to places like SeaWorld, downtown gas lamp, zoo. I loved the view from the balcony. My wife and I will definitely come back to stay here. Oh and a nearby Tesla supercharger only 1.2miles from the hotel. " [](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ## Frequently asked questions ### Looking to vacation at a spa hotel in University City? ### What's there to see and do in University City? ### What is a University City spa hotel? ## Explore a world of travel with Expedia - Lodging - More ways to book - [Beach Hotel Hotels in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Beach-Hotel.0-0-d6068523-tBeachHotel.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotels-With-Indoor-Pool.0-0-d6068523-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Oceanfront-Hotels.0-0-d6068523-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Ski Hotels in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Ski-Hotel.0-0-d6068523-tSkiHotel.Travel-Guide-Filter-Hotels) - 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