Title: Book The Best Hotels in Louisiana, MO for 2025 from CA $87 - Competitive Prices - Expedia.ca [Vacation Rentals in Louisiana](https://expedia.ca/Louisiana-Vacation-Rentals.d127811.Travel-Guide-VacationRentals)[Flights to Louisiana](https://expedia.ca/Cheap-Flights-To-Louisiana.d127811.Travel-Guide-Flights)[Louisiana Car Rentals](https://expedia.ca/Car-Rentals-In-Louisiana.d127811.Car-Rental-Guide)[Louisiana Vacation Packages](https://expedia.ca/Louisiana.d127811.Destination-Travel-Guides) ![Open swing span of Louisiana railroad bridge across the upper Mississippi near the town of Louisiana in Missouri](https://images.trvl-media.com/place/127811/d3a11af1-a4bc-4d21-8f62-58cf4c9cc04d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Louisiana, MO from CA $87 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Louisiana Pool [](https://www.expedia.ca/Hotel-Search?destination=Louisiana%2C+Missouri%2C+United+States+of+America®ionId=127811&latLong=39.448937%2C-91.051529&adults=2&startDate=2025-11-09&d1=2025-11-09&endDate=2025-11-11&d2=2025-11-11&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Louisiana%2C+Missouri%2C+United+States+of+America®ionId=127811&latLong=39.448937%2C-91.051529&adults=2&startDate=2025-11-09&d1=2025-11-09&endDate=2025-11-11&d2=2025-11-11&amenities=HOT_TUB) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Louisiana%2C+Missouri%2C+United+States+of+America®ionId=127811&latLong=39.448937%2C-91.051529&adults=2&startDate=2025-11-09&d1=2025-11-09&endDate=2025-11-11&d2=2025-11-11&amenities=PETS) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Louisiana%2C+Missouri%2C+United+States+of+America®ionId=127811&latLong=39.448937%2C-91.051529&adults=2&startDate=2025-11-09&d1=2025-11-09&endDate=2025-11-11&d2=2025-11-11&travelerType=family_friendly) ## Check prices for these dates Tonight [Oct 26 - Oct 27](https://www.expedia.ca/Hotel-Search?regionId=127811&startDate=2025-10-26&endDate=2025-10-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 27 - Oct 28](https://www.expedia.ca/Hotel-Search?regionId=127811&startDate=2025-10-27&endDate=2025-10-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=127811&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=127811&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 83 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Balcony](https://images.trvl-media.com/lodging/13000000/12240000/12232200/12232142/9e5d5186.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/13000000/12240000/12232200/12232142/48a0e756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/13000000/12240000/12232200/12232142/e95aba72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/13000000/12240000/12232200/12232142/fcd7f602.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### River's Edge Motel Louisiana 9.0/10 Wonderful (349) "Clean,quiet, easy parking and great view of the river." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edward CA $112 CA $127 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Hannibal-Hotels-Rivers-Edge-Motel.h12232142.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/112000000/111950000/111944700/111944656/9536012a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111950000/111944700/111944656/2c8ee78f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, Italian cuisine](https://images.trvl-media.com/lodging/112000000/111950000/111944700/111944656/9be9497f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/112000000/111950000/111944700/111944656/50983b3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Eagles Nest Inn Louisiana 9.4/10 Exceptional (18) "The room was great. Large and attractive!! Nice bathroom. Had all the convenience you need from TV to mini frig. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Judith CA $129 CA $147 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Louisiana-Hotels-The-Eagles-Nest-Inn.h111944656.Hotel-Information) ![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/b520e740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/ba8e13b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/f41d8ca0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/721fce3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western On The River Hannibal 8.6/10 Excellent (1004) "Walkable to the historic downtown area and great breakfast choices." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dave CA $154 CA $177 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Hannibal-Hotels-Best-Western-On-The-River.h16249.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/13b9e861.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/937d7fc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/664b263a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/12a7ffe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Hannibal West Hannibal 8.0/10 Very good (1020) "Hot tub in the room is nice The pool was great! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Troy CA $122 CA $140 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Hannibal-Hotels-Quality-Inn-Suites-Hannibal.h983646.Hotel-Information) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/4000000/3800000/3790200/3790159/69dacd1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/4000000/3800000/3790200/3790159/ad87f56f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/4000000/3800000/3790200/3790159/9bcb70db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/4000000/3800000/3790200/3790159/d2c89a48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Hannibal Hannibal 6.2/10 (719) " There actually was a pool & there actually was a hot breakfast. It didn't just say there was & not have what was listed. One of the best we've been to as of late. Would stay again if in the area. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $88 CA $102 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Hannibal-Hotels-Hannibal-Inn.h3790159.Hotel-Information) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/70000/64300/64231/e4d50f81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/64300/64231/3ec3fc7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/70000/64300/64231/a188d547.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/64300/64231/87b01476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites - Hannibal Hannibal 7.6/10 Good (644) "The beds were super comfy" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jayme CA $125 CA $143 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Hannibal-Hotels-Comfort-Inn-Suites-Hannibal.h64231.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/0683cbec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/9648a7bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/987b9fd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/cb88733c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Hannibal West Hannibal 9.6/10 Exceptional (1005) "great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Guy CA $150 CA $174 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Hannibal-Hotels-Sleep-Inn-Suites.h11308942.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/13000/12968/a819ab14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/20000/13000/12968/83466281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13000/12968/bb8f8176.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/13000/12968/89ea3311.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Hannibal Hannibal 7.4/10 Good (207) "very average but right off the highway, so was convenient." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $92 CA $106 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Hannibal-Hotels-Days-Inn-By-Wyndham-Hannibal.h12968.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/28400/28323/f0f94864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/28400/28323/de2c250a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/28400/28323/fe4b7593.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/28400/28323/3c17c168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Hannibal, MO Hannibal 7.4/10 Good (1005) "Very clean rooms and staff is very friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sherrie CA $77 CA $88 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Hannibal-Hotels-Motel-6-Hannibal.h28323.Hotel-Information) ![Breakfast meal](https://images.trvl-media.com/lodging/7000000/6660000/6659600/6659525/080807c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6660000/6659600/6659525/8fabc5ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6660000/6659600/6659525/e9628a93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, Ensuite (Double Queen Suite)](https://images.trvl-media.com/lodging/7000000/6660000/6659600/6659525/8f50dc31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### William Watson Hotel Pittsfield 9.2/10 Wonderful (341) "Great place to stay! Brandi is the best." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth CA $126 CA $139 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Pittsfield-Hotels-William-Watson-Hotel.h6659525.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/6000000/5640000/5637500/5637460/0aa674c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/6000000/5640000/5637500/5637460/13f55165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/6000000/5640000/5637500/5637460/16c3be32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5637500/5637460/74c9995c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn Pittsfield 6.8/10 (121) "I could not check in because the clerk never showed up to check us in. 2 hours at least with two trips to the site and 3 phone calls. I could not get anyone to talk to or check us in. I left a message that we were cancelling and we went to another motel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve CA $85 CA $93 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/Pittsfield-Hotels-Rodeway-Inn.h5637460.Hotel-Information) ![Deluxe Room](https://images.trvl-media.com/lodging/106000000/105130000/105120300/105120258/fb550013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/106000000/105130000/105120300/105120258/4063c21a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite | Living area](https://images.trvl-media.com/lodging/106000000/105130000/105120300/105120258/1abb1816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/106000000/105130000/105120300/105120258/d6514417.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lighthouse Inn & Suites Hannibal 8.8/10 Excellent (23) "Very nice room, close enough to walk to riverfront attractions. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $236 CA $271 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Hannibal-Hotels-Lighthouse-Inn-Suites.h105120258.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/77000000/76270000/76266600/76266570/067469c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/77000000/76270000/76266600/76266570/6002c086.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/77000000/76270000/76266600/76266570/237b6bb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/77000000/76270000/76266600/76266570/b7a06020.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson BY Wyndham Hannibal Hannibal 7.2/10 Good (140) "Wonderful and friendly staff, an actual hot real breakfast selection! Clean pool and gaming area, would stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Justin CA $76 CA $87 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Hannibal-Hotels-Howard-Johnson-BY-Wyndham-Hannibal.h76266570.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/104000000/103850000/103844400/103844330/087adb03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/104000000/103850000/103844400/103844330/0f6bae6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/104000000/103850000/103844400/103844330/6ad6820a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/104000000/103850000/103844400/103844330/88cd794c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Garden House Bed and Breakfast Hannibal 8.4/10 Very good (31) "A beautiful 19th century mansion, decorated in period. Quiet and comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $134 CA $154 total includes taxes & fees Nov 26 - Nov 27 [](https://www.expedia.ca/Hannibal-Hotels-Garden-House-Bed-And-Breakfast.h103844330.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9990000/9986700/9986625/a368327c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/10000000/9990000/9986700/9986625/c466d62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Refrigerator (New building)](https://images.trvl-media.com/lodging/10000000/9990000/9986700/9986625/2c579c3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9990000/9986700/9986625/a47c0b8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Green Acres Hotel Pittsfield 8.6/10 Excellent (140) "Wonderful stay - was staying with a number of family members and it all worked out" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard CA $167 CA $183 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Pittsfield-Hotels-Green-Acres-Hotel.h9986625.Hotel-Information) ![Comfort Room](https://images.trvl-media.com/lodging/18000000/17050000/17047300/17047233/7fa649ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/18000000/17050000/17047300/17047233/47811fea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/18000000/17050000/17047300/17047233/b4ce7d70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/18000000/17050000/17047300/17047233/873e4e0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Monroe Street Suites Pittsfield 9.6/10 Exceptional (57) "Definitely one of the best hotels I’ve ever stayed in. Super quiet, clean, convenient, it’s located in town, which there were plenty of shopping and food options. Overall, I would definitely recommend this hotel. And I will be staying there again in the future." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jake CA $164 CA $181 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Pittsfield-Hotels-Monroe-Street-Suites.h17047233.Hotel-Information) ![55-inch TV with cable channels, Netflix, Hulu](https://images.trvl-media.com/lodging/38000000/37180000/37171800/37171765/68b34759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge, coffee/tea maker](https://images.trvl-media.com/lodging/38000000/37180000/37171800/37171765/3443f541.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Studio Suite](https://images.trvl-media.com/lodging/38000000/37180000/37171800/37171765/a138c2a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/38000000/37180000/37171800/37171765/39c331f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riverside Inn Hannibal Hannibal 9.4/10 Exceptional (160) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandy CA $194 CA $271 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Hannibal-Hotels-Riverside-Inn.h37171765.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-09&endDate=2025-11-10®ionId=127811&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLouisiana-Hotels.d127811.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLouisiana-Hotels.d127811.Travel-Guide-Hotels) ## Learn more about Louisiana Like rivers? Get away to relaxing Louisiana! [See all hotels in Louisiana](https://www.expedia.ca/Hotel-Search?startDate=2025-11-09&endDate=2025-11-10&adults=2®ionId=127811) ![Open swing span of Louisiana railroad bridge across the upper Mississippi near the town of Louisiana in Missouri](https://images.trvl-media.com/place/127811/d3a11af1-a4bc-4d21-8f62-58cf4c9cc04d.jpg?impolicy=fcrop&w=900&h=569&p=1&q=high) ## More cheap stays in Louisiana ![Quality Inn & Suites Hannibal](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/13b9e861_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn & Suites Hannibal 120 Lindsey Drive, Hannibal, MO CA $122 CA $140 total Nov 2 - Nov 3 includes taxes & fees 7.8/10 Good! (1,017 reviews) [](https://expedia.ca/Hannibal-Hotels-Quality-Inn-Suites-Hannibal.h983646.Hotel-Information) ![Best Western On The River](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/b520e740_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western On The River 401 North 3rd Street, Hannibal, MO CA $154 CA $177 total Nov 2 - Nov 3 includes taxes & fees 8.6/10 Excellent! (1,003 reviews) [](https://expedia.ca/Hannibal-Hotels-Best-Western-On-The-River.h16249.Hotel-Information) ![Sleep Inn & Suites](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/0683cbec_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sleep Inn & Suites 105 Lakeside Dr, Hannibal, MO CA $150 CA $174 total Nov 2 - Nov 3 includes taxes & fees 9.6/10 Exceptional! (1,000 reviews) [](https://expedia.ca/Hannibal-Hotels-Sleep-Inn-Suites.h11308942.Hotel-Information) ![Motel 6 Hannibal, MO](https://images.trvl-media.com/lodging/1000000/30000/28400/28323/f0f94864_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel 6 Hannibal, MO 123 Huckleberry Heights Dr, Hannibal, MO CA $77 CA $88 total Nov 1 - Nov 2 includes taxes & fees 7.4/10 Good! (1,003 reviews) [](https://expedia.ca/Hannibal-Hotels-Motel-6-Hannibal.h28323.Hotel-Information) ![Baymont by Wyndham Hannibal](https://images.trvl-media.com/lodging/4000000/3800000/3790200/3790159/69dacd1b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Hannibal 4141 Market St, Hannibal, MO CA $88 CA $102 total Oct 27 - Oct 28 includes taxes & fees 6.2/10 (715 reviews) [](https://expedia.ca/Hannibal-Hotels-Hannibal-Inn.h3790159.Hotel-Information) ![Comfort Inn & Suites - Hannibal](https://images.trvl-media.com/lodging/1000000/70000/64300/64231/e4d50f81_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Inn & Suites - Hannibal 4000 Market St, Hannibal, MO CA $125 CA $143 total Nov 2 - Nov 3 includes taxes & fees 7.6/10 Good! (643 reviews) [](https://expedia.ca/Hannibal-Hotels-Comfort-Inn-Suites-Hannibal.h64231.Hotel-Information) ## Recent reviews of Louisiana hotels ![Lighthouse Inn & Suites](//images.trvl-media.com/lodging/106000000/105130000/105120300/105120258/fb550013_y.jpg) ### Lighthouse Inn & Suites 5/5 Excellent "Great experience, clean room. " A verified traveller stayed at Lighthouse Inn & Suites Posted 3 days ago [](https://expedia.ca/Hannibal-Hotels-Lighthouse-Inn-Suites.h105120258.Hotel-Information) ![Quality Inn & Suites Hannibal](//images.trvl-media.com/lodging/1000000/990000/983700/983646/13b9e861_y.jpg) ### Quality Inn & Suites Hannibal 5/5 Excellent "Great staff. Property a bit outdated. Noise from person walking in room upstairs (older construction). " A verified traveller stayed at Quality Inn & Suites Hannibal Posted 3 days ago [](https://expedia.ca/Hannibal-Hotels-Quality-Inn-Suites-Hannibal.h983646.Hotel-Information) ![Comfort Inn & Suites - Hannibal](//images.trvl-media.com/lodging/1000000/70000/64300/64231/e4d50f81_y.jpg) ### Comfort Inn & Suites - Hannibal 5/5 Excellent "Clean room, comfortable bed" A verified traveller stayed at Comfort Inn & Suites - Hannibal Posted 5 days ago [](https://expedia.ca/Hannibal-Hotels-Comfort-Inn-Suites-Hannibal.h64231.Hotel-Information) ![Best Western On The River](//images.trvl-media.com/lodging/1000000/20000/16300/16249/b520e740_y.jpg) ### Best Western On The River 5/5 Excellent "The room was very comfortable." A verified traveller stayed at Best Western On The River Posted 5 days ago [](https://expedia.ca/Hannibal-Hotels-Best-Western-On-The-River.h16249.Hotel-Information) ![Sleep Inn & Suites](//images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/0683cbec_y.jpg) ### Sleep Inn & Suites 5/5 Excellent "The breakfast menu was fresh and plenty of options." A verified traveller stayed at Sleep Inn & Suites Posted 7 days ago [](https://expedia.ca/Hannibal-Hotels-Sleep-Inn-Suites.h11308942.Hotel-Information) ![Baymont by Wyndham Hannibal](//images.trvl-media.com/lodging/4000000/3800000/3790200/3790159/69dacd1b_y.jpg) ### Baymont by Wyndham Hannibal 5/5 Excellent " There actually was a pool & there actually was a hot breakfast. It didn't just say there was & not have what was listed. One of the best we've been to as of late. Would stay again if in the area. " A verified traveller stayed at Baymont by Wyndham Hannibal Posted 8 days ago [](https://expedia.ca/Hannibal-Hotels-Hannibal-Inn.h3790159.Hotel-Information) ![Riverside Inn Hannibal](//images.trvl-media.com/lodging/38000000/37180000/37171800/37171765/68b34759_y.jpg) ### Riverside Inn Hannibal 5/5 Excellent "Perfect spot for our visit to Hannibal during its fall festival. Everything was within walking distance, the room was spacious and comfortable and the communication with the property was prompt and helpful. I enjoyed the window view overlooking the levee and Mississippi River. We chatted with passengers getting back on the Viking River cruise at the port. A nice selection of casual dining options on Main. " A verified traveller stayed at Riverside Inn Hannibal Posted 8 days ago [](https://expedia.ca/Hannibal-Hotels-Riverside-Inn.h37171765.Hotel-Information) ![Garden House Bed and Breakfast](//images.trvl-media.com/lodging/104000000/103850000/103844400/103844330/087adb03_y.jpg) ### Garden House Bed and Breakfast 5/5 Excellent Great B&B "Host was helpful with local suggestions for things to and places to eat, as well as local history etc. Room was clean and comfortable, breakfast delicious and social. Gret spit close to downtown " A verified traveller stayed at Garden House Bed and Breakfast Posted 13 days ago [](https://expedia.ca/Hannibal-Hotels-Garden-House-Bed-And-Breakfast.h103844330.Hotel-Information) ![Motel 6 Hannibal, MO](//images.trvl-media.com/lodging/1000000/30000/28400/28323/f0f94864_y.jpg) ### Motel 6 Hannibal, MO 5/5 Excellent "It was a great place to stay the night while traveling. I really like the hard floor upgrade." A verified traveller stayed at Motel 6 Hannibal, MO Posted 2 weeks ago [](https://expedia.ca/Hannibal-Hotels-Motel-6-Hannibal.h28323.Hotel-Information) ## Frequently asked questions ### What are the best family hotels in Louisiana? > [The Eagles Nest Inn](https://www.expedia.ca/Louisiana-Hotels-The-Eagles-Nest-Inn.h111944656.Hotel-Information) in Louisiana is a charming family-friendly hotel great for those traveling with children. With thoughtful amenities like a dedicated Kids Meal program and convenient in-room microwaves, this hotel ensures that families can enjoy meals tailored to their little ones while also having the flexibility to prepare snacks or quick bites. Find more [child-friendly accommodations in Louisiana](https://www.expedia.ca/Louisiana-Hotels-Family-Hotel.0-0-d127811-tFamilyHotel.Travel-Guide-Filter-Hotels). ### What are the best budget hotels in Louisiana? > [River's Edge Motel](https://www.expedia.ca/Hannibal-Hotels-Rivers-Edge-Motel.h12232142.Hotel-Information) is an excellent choice for budget-conscious travellers seeking comfort and convenience in Louisiana, MO. With an excellent review score of 8.8, guests appreciate the inviting space and thoughtful amenities, including free toiletries and in-room WiFi, superb for staying connected while on the go. View all [budget hotels in Louisiana](https://www.expedia.ca/Louisiana-Hotels-Cheap-Hotels.0-0-d127811-tCheapHotels.Travel-Guide-Filter-Hotels). ### When is the best time to go to Louisiana? > The most popular time to visit Louisiana is April, when the state bursts into life with vibrant festivals and warm, welcoming weather. During this period, average temperatures range from 18°C to 26°C, making it ideal for exploring the rich culture of cities like New Orleans and Baton Rouge, as well as enjoying the stunning landscapes of the bayous and plantations. > > > > The peak season in Louisiana runs from April to June, attracting tourists eager to experience the lively atmosphere of springtime celebrations. This is when the famous Jazz & Heritage Festival takes place, offering an authentic taste of the local music scene, delicious cuisine, and an opportunity to mingle with fellow travellers and locals alike. As you wander through the historic streets, the mild climate allows for comfortable outdoor activities, whether that's taking a leisurely stroll down Magazine Street or enjoying a riverboat cruise on the Mississippi. > > > > For those who appreciate good value without compromising on quality, November can be an excellent alternative. While the tourist crowds have thinned, the climate is still pleasant, with temperatures typically ranging from 12°C to 22°C. This quieter time allows for a more intimate exploration of Louisiana's unique landscapes and cultural offerings, without the hustle and bustle of peak season. ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Louisiana. ### How can I save on a Louisiana hotel booking with Expedia? > Members always get our best prices. Find our best Louisiana hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings. ### How much is the nightly rate at a Louisiana hotel? > Prices for hotels in Louisiana often vary, but you can find a great deal from CA $87 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. 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