Title: Hotels by Wyndham Hotels in Texas Medical Center from CA $90 | Expedia.ca [Texas Medical Center Travel Guide](https://expedia.ca/Houston-Texas-Medical-Center.dx6143504)[Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[Texas Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Texas-Medical-Center.d6143504.Car-Rental-Guide)[Texas Medical Center Vacations](https://expedia.ca/Texas-Medical-Center.d6143504.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/f4655cac96c82fca6c00f4ab3162178c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Wyndham Hotels in Texas Medical Center from CA $90 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 3 - Oct 4](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-10-03&endDate=2025-10-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 4 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-10-04&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Texas Medical Center Wyndham Hotels Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/64200/64160/d042d154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/64200/64160/57c287ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/70000/64200/64160/caf434d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/64200/64160/b1afee2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham Sugar Land 8.8/10 Excellent (1003) "Great stay" CA $117 CA $135 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Houston-Hotels-Heritage-Inn-Suites-HoustonSugar-Land.h64160.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/w2558h1440x0y0-44773629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pet-friendly](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/982edefb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/63833027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 10:00 AM to 6:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/e04a9b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Houston near NRG Park/Medical Center South Main 7.2/10 Good (1173) "Everyone was very pleasant, I will be returning." CA $138 CA $162 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) ![Pillowtop beds, individually decorated, individually furnished](https://images.trvl-media.com/lodging/41000000/40190000/40186600/40186592/5d4fd018.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, Multiple Beds](https://images.trvl-media.com/lodging/41000000/40190000/40186600/40186592/a2a168ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 King Bed (Studio) | Living area](https://images.trvl-media.com/lodging/41000000/40190000/40186600/40186592/99ee962a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment, 1 King Bed, Corner (Corner Suite)](https://images.trvl-media.com/lodging/41000000/40190000/40186600/40186592/54edcc18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reside Houston Dwntwn, Wyndham Downtown Houston 8.6/10 Excellent (817) "Great place to stay!" CA $176 CA $206 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Houston-Hotels-Sonder-The-Hogg-Palace.h40186592.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27700/27662/f7140d86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/27700/27662/8a2cc3ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![American cuisine](https://images.trvl-media.com/lodging/1000000/30000/27700/27662/0d5c955d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27700/27662/bf94d0be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Houston Hobby Airport Southeast Houston 6.8/10 (940) "Convenient to airport" CA $77 CA $90 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Houston-Hotels-Holiday-Inn-Houston-Hobby-Airport.h27662.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6400/6399/c0c41356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6400/6399/a57dbff1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6400/6399/b6e5c322.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/6400/6399/2680d25b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Houston Sugarland Alief 3.6/10 (5) "I booked my trip on 6/5/25 and arrived on my flight 7/4/25 for vacation. I booked a hotel for Holiday Inn. When I walked inside I was told the Holiday Inn no longer exist there and that they are Wyndham now. Well, they did not have a room for me but somebody has my money. I was told to contact IHG/Holiday Inn. They refused to refund my money for a hotel that does not exist anymore. I paid my money and I had to ride around in city that I am not familiar with to find a hotel. I road around for... CA $93 CA $109 total includes taxes & fees Oct 6 - Oct 7 [](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Sugarland.h6399.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-18&endDate=2025-10-19®ionId=6143504&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FTexas-Medical-Center-Houston-Hotels-Wyndham-Hotels.0-n6143504-0--bWyndhamHotels.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FTexas-Medical-Center-Houston-Hotels-Wyndham-Hotels.0-n6143504-0--bWyndhamHotels.Travel-Guide-Filter-Hotels) ## Top Texas Medical Center Hotel Reviews ![Blossom Hotel Houston](//images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/dc9d050c_y.jpg) ### Blossom Hotel Houston 10/10 Excellent "This was our third stay at the hotel, The staff are always very friendly and helpful, making us feel welcome every time. It’s a wonderful place to stay, especially if you need to be near the medical center. Highly recommended!" [](https://expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) ![Hilton Americas-Houston](//images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59_y.jpg) ### Hilton Americas-Houston 10/10 Excellent "Very beautiful hotel" [](https://expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) ![C. Baldwin, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/30000/25000/24968/dbf192ed_y.jpg) ### C. Baldwin, Curio Collection by Hilton 10/10 Excellent "I loved the shuttle/" [](https://expedia.ca/Houston-Hotels-C-Baldwin.h24968.Hotel-Information) ![Hyatt Place Houston Medical Center](//images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/6621e9bb_y.jpg) ### Hyatt Place Houston Medical Center 10/10 Excellent "We appreciate the staff's friendliness, which contributes to a pleasant environment. The rooms consistently meet our standards with their cleanliness, providing a comfortable stay. Moreover, the poolside offers a relaxing space, perfect for unwinding. These aspects create a positive experience for all guests. Therefore, we are grateful for the overall quality. " [](https://expedia.ca/Houston-Hotels-Hyatt-Place-Houston-Medical-Center.h88130440.Hotel-Information) ![DoubleTree by Hilton Hotel & Suites Houston by the Galleria](//images.trvl-media.com/lodging/1000000/30000/20200/20116/555244ce_y.jpg) ### DoubleTree by Hilton Hotel & Suites Houston by the Galleria 10/10 Excellent "It was great customer service " [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Suites-Houston-By-The-Galleria.h20116.Hotel-Information) ![Crowne Plaza Houston Med Ctr-Galleria Area by IHG](//images.trvl-media.com/lodging/1000000/30000/28100/28060/38218191_y.jpg) ### Crowne Plaza Houston Med Ctr-Galleria Area by IHG 10/10 Excellent "Very good" [](https://expedia.ca/Houston-Hotels-Crowne-Plaza-Houston-River-Oaks.h28060.Hotel-Information) ![The Whitehall Houston](//images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056_y.jpg) ### The Whitehall Houston 10/10 Excellent "My stay was amazing with such beautiful and spacious rooms! I loved how the hotel reached out to me before my stay and offered upgrades. My plans did change last minute, and being able to updrade to a 2 bed was perfect. The staff was extremely helpful as well. I will definitely return when I plan to visit Houston! " [](https://expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information) ![Club Quarters Hotel Downtown, Houston](//images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd_y.jpg) ### Club Quarters Hotel Downtown, Houston 10/10 Excellent "Staff was amazing! Every single one. Hotel is close to all financial building downtown, walkable distance. " [](https://expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![DoubleTree by Hilton Hotel Houston - Greenway Plaza](//images.trvl-media.com/lodging/1000000/30000/20200/20177/682ca680_y.jpg) ### DoubleTree by Hilton Hotel Houston - Greenway Plaza 10/10 Excellent "Will stay again " [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Houston-Greenway-Plaza.h20177.Hotel-Information) ## Find out more about Texas Medical Center ## Texas Medical Center Hotels Guide Expedia.ca offers a selection of 6624 hotels in Texas Medical Center. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Texas Medical Center. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Texas Medical Center neighborhood you prefer. Go ahead. Enter your travel dates to view the best offers on hotel rooms in Texas Medical Center, Houston now! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [3 Star Hotels in Houston Museum District](https://www.expedia.ca/3Star-Houston-Museum-District-Houston-Hotels.s30-n6164045-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Houston Museum District](https://www.expedia.ca/5Star-Houston-Museum-District-Houston-Hotels.s50-n6164045-0.Travel-Guide-Filter-Hotels) - [Casino Hotels in Astrodome](https://www.expedia.ca/Astrodome-Houston-Hotels-Casino-Hotel.0-n553248635976007975-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Astrodome](https://www.expedia.ca/Astrodome-Houston-Hotels-Cheap-Hotels.0-n553248635976007975-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Astrodome](https://www.expedia.ca/Astrodome-Houston-Hotels-Luxury-Hotel.0-n553248635976007975-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Astrodome](https://www.expedia.ca/Astrodome-Houston-Hotels-Spa-Hotel.0-n553248635976007975-0-tSpaHotel.Travel-Guide-Filter-Hotels) - 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