Title: Hotels by Wyndham Hotels in Texas Medical Center from CA $71 | Expedia.ca [Texas Medical Center Travel Guide](https://expedia.ca/Houston-Texas-Medical-Center.dx6143504)[Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[Texas Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Texas-Medical-Center.d6143504.Car-Rental-Guide)[Texas Medical Center Vacations](https://expedia.ca/Texas-Medical-Center.d6143504.Destination-Travel-Guides) ![Houston_TexasChildrensHospital_553248635389801905_9](https://images.trvl-media.com/place/553248635389801905/db4dee74-4310-41e3-8220-625d7fc800e9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Wyndham Hotels in Texas Medical Center from CA $71 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 10 - Dec 11](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-12-10&endDate=2025-12-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 11 - Dec 12](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-12-11&endDate=2025-12-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Texas Medical Center Wyndham Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/64200/64160/d042d154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/64200/64160/c00587af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/70000/64200/64160/caf434d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/64200/64160/57c287ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham [](https://www.expedia.ca/Houston-Hotels-Heritage-Inn-Suites-HoustonSugar-Land.h64160.Hotel-Information) Sugar Land 8.8/10 Excellent (1006) "Room was great, area is quiet and easy access to restaurants and stores" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $117 CA $134 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Houston-Hotels-Heritage-Inn-Suites-HoustonSugar-Land.h64160.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6400/6399/c0c41356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6400/6399/8e1b1cb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/6400/6399/2680d25b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6400/6399/a57dbff1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Houston Sugarland [](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Sugarland.h6399.Hotel-Information) Alief 5.2/10 (35) "Under construction and they don’t tell u this before y reserve" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Soumia CA $79 CA $92 total includes taxes & fees Dec 13 - Dec 14 [](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Sugarland.h6399.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/w2558h1440x0y0-44773629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/63833027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 10:00 AM to 6:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/e04a9b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pet-friendly](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/982edefb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Houston near NRG Park/Medical Center [](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) South Main 7.2/10 Good (1195) "Love this place. Been staying here for many years. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reynaldo CA $123 CA $144 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27700/27662/f7140d86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/27700/27662/6ae178c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![American cuisine](https://images.trvl-media.com/lodging/1000000/30000/27700/27662/0d5c955d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27700/27662/bf94d0be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Houston Hobby Airport [](https://www.expedia.ca/Houston-Hotels-Holiday-Inn-Houston-Hobby-Airport.h27662.Hotel-Information) Southeast Houston 6.8/10 (991) "Not a great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Willie CA $61 CA $71 total includes taxes & fees Dec 31 - Jan 1, 2026 [](https://www.expedia.ca/Houston-Hotels-Holiday-Inn-Houston-Hobby-Airport.h27662.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/41000000/40190000/40186600/40186592/e2746fe1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 1 King Bed (Suite) | Private kitchen](https://images.trvl-media.com/lodging/41000000/40190000/40186600/40186592/w2998h2000x0y0-8469df9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Queen Bed (Studio) | Living area](https://images.trvl-media.com/lodging/41000000/40190000/40186600/40186592/eeca9d82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, individually decorated, individually furnished](https://images.trvl-media.com/lodging/41000000/40190000/40186600/40186592/9623c809.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reside Houston Dwntwn, Wyndham [](https://www.expedia.ca/Houston-Hotels-Sonder-The-Hogg-Palace.h40186592.Hotel-Information) Downtown Houston 8.6/10 Excellent (849) "Iwe really enjoyed our stay and will stay again in the future" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul CA $165 CA $193 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Houston-Hotels-Sonder-The-Hogg-Palace.h40186592.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-24&endDate=2025-12-25®ionId=6143504&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FTexas-Medical-Center-Houston-Hotels-Wyndham-Hotels.0-n6143504-0--bWyndhamHotels.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FTexas-Medical-Center-Houston-Hotels-Wyndham-Hotels.0-n6143504-0--bWyndhamHotels.Travel-Guide-Filter-Hotels) ## Top Texas Medical Center Hotel Reviews ![Blossom Hotel Houston, Curio Collection by Hilton](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/db7ae93f_y.jpg) ### Blossom Hotel Houston, Curio Collection by Hilton 10/10 Excellent "Great" [](https://expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) ![Hyatt House Houston Medical Center](https://images.trvl-media.com/lodging/84000000/83760000/83751000/83750993/31c2b88f_y.jpg) ### Hyatt House Houston Medical Center 10/10 Excellent "It was quite nice. I dont usually stay in hotels of this caliber. The room was fabulous and clean with great views of medical center. It was a nice treat. My son was having a major surgery at MDA. The hotel shuttle service was such a blessing as it covered the MDA area. Our shuttle driver was an incredibly kind gentlemen that went out of his way to be helpful. Sure wish we could remember his name. It was convenient to MDA which allowed an option to walk which we did quite often. The breakfast was plenty good. Just wish there was a bit more variety. The attendants were awesome. Really would have enjoyed the option for coffee available in foyer. Very helpful desk attendants. Reasonable parking prices and safe atmosphere. Would most definitely stay again!!" [](https://expedia.ca/Houston-Hotels-Hyatt-House-Houston-Medical-Center.h83750993.Hotel-Information) ![Magnolia Hotel Houston, A Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37_y.jpg) ### Magnolia Hotel Houston, A Tribute Portfolio Hotel 10/10 Excellent "Room was amazing. Quiet. Shower was excellent. Staff was friendly. " [](https://expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) ![DoubleTree by Hilton Hotel Houston - Greenway Plaza](https://images.trvl-media.com/lodging/1000000/30000/20200/20177/682ca680_y.jpg) ### DoubleTree by Hilton Hotel Houston - Greenway Plaza 10/10 Excellent "All of the above, actually. But in addition, I had left a personal item in the room after checkout. And the staff found and agreed to return it to me. I'm very appreciative of this "above and beyond" customer care. Thank you!! " [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Houston-Greenway-Plaza.h20177.Hotel-Information) ![Hilton Houston Plaza/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50_y.jpg) ### Hilton Houston Plaza/Medical Center 10/10 Excellent "yes" [](https://expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![The Whitehall Houston](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056_y.jpg) ### The Whitehall Houston 10/10 Excellent "Room was clean, convenient location, friendly staff, excellent breakfast" [](https://expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information) ![The Westin Galleria Houston](https://images.trvl-media.com/lodging/1000000/20000/11200/11117/b45a8086_y.jpg) ### The Westin Galleria Houston 10/10 Excellent "Staff" [](https://expedia.ca/Houston-Hotels-The-Westin-Galleria-Houston.h11117.Hotel-Information) ![Omni Houston Hotel](https://images.trvl-media.com/lodging/1000000/20000/17800/17746/37423ee4_y.jpg) ### Omni Houston Hotel 10/10 Excellent "Beautiful, clean rooms and staff extremely accommodating. " [](https://expedia.ca/Houston-Hotels-Omni-Houston-Hotel.h17746.Hotel-Information) ![The Westin Houston Medical Center/Museum District](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/a994a387_y.jpg) ### The Westin Houston Medical Center/Museum District 10/10 Excellent "Staff was friendly and welcoming. Room and hotel were clean, beautifully decorated for the holidays. Bed was super comfortable. Would definitely stay again." [](https://expedia.ca/Houston-Hotels-The-Westin-Houston-Medical-Center.h39618635.Hotel-Information) ## Find out more about Texas Medical Center ## Texas Medical Center Hotels Guide Expedia.ca offers a selection of 6837 hotels in Texas Medical Center. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Texas Medical Center. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Texas Medical Center neighborhood you prefer. Go ahead. Enter your travel dates to view the best offers on hotel rooms in Texas Medical Center, Houston now! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [3 Star Hotels in Houston Museum District ](https://www.expedia.ca/3Star-Houston-Museum-District-Houston-Hotels.s30-n6164045-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Houston Museum District ](https://www.expedia.ca/5Star-Houston-Museum-District-Houston-Hotels.s50-n6164045-0.Travel-Guide-Filter-Hotels) - [Casino Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Casino-Hotel.0-n553248635976007975-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Cheap-Hotels.0-n553248635976007975-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Luxury-Hotel.0-n553248635976007975-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Spa-Hotel.0-n553248635976007975-0-tSpaHotel.Travel-Guide-Filter-Hotels) - 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