Title: Hotels by Hilton Hotels in Texas Medical Center from CA $130 | Expedia.ca [Texas Medical Center Travel Guide](https://expedia.ca/Houston-Texas-Medical-Center.dx6143504)[Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[Texas Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Texas-Medical-Center.d6143504.Car-Rental-Guide)[Texas Medical Center Vacations](https://expedia.ca/Texas-Medical-Center.d6143504.Destination-Travel-Guides) ![Houston_TexasChildrensHospital_553248635389801905_9](https://images.trvl-media.com/place/553248635389801905/db4dee74-4310-41e3-8220-625d7fc800e9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248635389801905/db4dee74-4310-41e3-8220-625d7fc800e9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 22 - Jan 23](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2026-01-22&endDate=2026-01-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 23 - Jan 24](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2026-01-23&endDate=2026-01-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Texas Medical Center Hilton Hotels ![Indoor pool, open 6 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/w1800h1197x0y0-475f9f91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/cc938c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed | Bathroom](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/ba81228f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/51d97881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Americas-Houston [](https://www.expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) Downtown Houston 9.4/10 Exceptional (1,656 reviews) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shateke CA $305 CA $360 total includes taxes & fees Feb 6 - Feb 7 [](https://www.expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) ![Serves dinner and happy hour](https://images.trvl-media.com/lodging/1000000/10000/900/809/72a26fde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/10000/900/809/7dd4c532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/809/d8b67d1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/900/809/aa98f077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston North [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-North.h809.Hotel-Information) Northside 8.2/10 Very good (1,005 reviews) "Hilton always takes care of accommodations " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donald CA $176 CA $206 total includes taxes & fees Feb 14 - Feb 15 [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-North.h809.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/77443f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/e15c188d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/280705eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/8964faa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston Plaza/Medical Center [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) Texas Medical Center 8.4/10 Very good (1,820 reviews) "Amazing room, great rate! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sherri CA $110 CA $130 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25600/25502/07704909.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/25600/25502/40af4923.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/25600/25502/4b8c552d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/30000/25600/25502/a8a495f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston Post Oak by the Galleria [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Post-Oak-By-The-Galleria.h25502.Hotel-Information) The Galleria 8.2/10 Very good (1,000 reviews) "Staff was great. Location was perfect. Great room size and amenities" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $203 CA $238 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Post-Oak-By-The-Galleria.h25502.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/19000000/18990000/18989200/18989138/3bf9eb6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/19000000/18990000/18989200/18989138/w3839h2500x0y56-386e2fdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/19000000/18990000/18989200/18989138/5d3afc58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/19000000/18990000/18989200/18989138/4c876336.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston Westchase [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Westchase.h18989138.Hotel-Information) Westchase 8.0/10 Very good (1,000 reviews) "Friendly staff and clean room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly CA $158 CA $185 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Westchase.h18989138.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40758/36b10bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/1000000/50000/40800/40758/310d4c81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/50000/40800/40758/d0cccaac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40758/1b52daf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton University of Houston [](https://www.expedia.ca/Houston-Hotels-Hilton-University-Of-Houston.h40758.Hotel-Information) Southeast Houston 9.0/10 Wonderful (890 reviews) "Nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexandra CA $214 CA $251 total includes taxes & fees Feb 6 - Feb 7 [](https://www.expedia.ca/Houston-Hotels-Hilton-University-Of-Houston.h40758.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-05&endDate=2026-02-06®ionId=6143504&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FTexas-Medical-Center-Houston-Hotels-Hilton-Hotels.0-n6143504-0--bHiltonHotels.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FTexas-Medical-Center-Houston-Hotels-Hilton-Hotels.0-n6143504-0--bHiltonHotels.Travel-Guide-Filter-Hotels) ## Top Texas Medical Center Hotel Reviews ![The Royal Sonesta Houston Galleria](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960_y.jpg) ### The Royal Sonesta Houston Galleria 10/10 Excellent "Excellent service, especially from Martha. They were all welcoming and accommodating." [](https://expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) ![Hilton Americas-Houston](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59_y.jpg) ### Hilton Americas-Houston 10/10 Excellent "Excellent as always " [](https://expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) ![Hyatt Place Houston Medical Center](https://images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/a6f86b3d_y.jpg) ### Hyatt Place Houston Medical Center 10/10 Excellent "Yes everything wasgreat as usual " [](https://expedia.ca/Houston-Hotels-Hyatt-Place-Houston-Medical-Center.h88130440.Hotel-Information) ![Hilton Houston Plaza/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50_y.jpg) ### Hilton Houston Plaza/Medical Center 10/10 Excellent "Staff is extremely hospitable. " [](https://expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![SpringHill Suites by Marriott Houston Intercontinental Arprt](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/69d373fc_y.jpg) ### SpringHill Suites by Marriott Houston Intercontinental Arprt 10/10 Excellent "The check in was a breeze. We arrived off our cruise at 830 am and arrived at the hotel at 11, and they were able to give us 1 room to store our luggage until the second room was ready. The staff were friendly and courteous. I will be recommending the hotel to my friends that travel. I can't say enough great things about this hotel." [](https://expedia.ca/Houston-Hotels-SpringHill-Suites-By-Marriott-Houston-Intercontinental-Arprt.h2964240.Hotel-Information) ![Blossom Hotel Houston, Curio Collection by Hilton](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/db7ae93f_y.jpg) ### Blossom Hotel Houston, Curio Collection by Hilton 10/10 Excellent "Great stay! Definitely will be back! " [](https://expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) ![Club Quarters Hotel Downtown, Houston](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd_y.jpg) ### Club Quarters Hotel Downtown, Houston 10/10 Excellent "Quick and easy. Only part is finding it with it being on the side valet " [](https://expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![Omni Houston Hotel](https://images.trvl-media.com/lodging/1000000/20000/17800/17746/37423ee4_y.jpg) ### Omni Houston Hotel 10/10 Excellent "Omni is always one of the best hotels I ever stay at from places in Florida to just getting a place in Houston for a night. It’s always great." [](https://expedia.ca/Houston-Hotels-Omni-Houston-Hotel.h17746.Hotel-Information) ![DoubleTree by Hilton Houston Medical Center Hotel & Suites](https://images.trvl-media.com/lodging/1000000/10000/6700/6636/w3835h2553x0y4-ca278b6c_y.jpg) ### DoubleTree by Hilton Houston Medical Center Hotel & Suites 10/10 Excellent "Excellent, spacious room" [](https://expedia.ca/Houston-Hotels-Wyndham-Houston-Medical-Center-Hotel-And-Suites.h6636.Hotel-Information) ## Find out more about Texas Medical Center ## Texas Medical Center Hotels Guide Expedia.ca offers a selection of 6792 hotels in Texas Medical Center. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Texas Medical Center. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Texas Medical Center neighborhood you prefer. Go ahead. Enter your travel dates to view the best offers on hotel rooms in Texas Medical Center, Houston now! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [3 Star Hotels in Houston Museum District ](https://www.expedia.ca/3Star-Houston-Museum-District-Houston-Hotels.s30-n6164045-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Houston Museum District ](https://www.expedia.ca/5Star-Houston-Museum-District-Houston-Hotels.s50-n6164045-0.Travel-Guide-Filter-Hotels) - [Casino Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Casino-Hotel.0-n553248635976007975-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Cheap-Hotels.0-n553248635976007975-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Luxury-Hotel.0-n553248635976007975-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Spa-Hotel.0-n553248635976007975-0-tSpaHotel.Travel-Guide-Filter-Hotels) - 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