Title: Book the Best ADVENTURE Hotels in Texas Medical Center in 2025 | Expedia.ca [Texas Medical Center Travel Guide](https://expedia.ca/Houston-Texas-Medical-Center.dx6143504)[Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[Texas Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Texas-Medical-Center.d6143504.Car-Rental-Guide)[Texas Medical Center Vacations](https://expedia.ca/Texas-Medical-Center.d6143504.Destination-Travel-Guides) ![Houston_TexasChildrensHospital_553248635389801905_9](https://images.trvl-media.com/place/553248635389801905/db4dee74-4310-41e3-8220-625d7fc800e9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels & Resorts for Couples in Texas Medical Center, TX from CA $128 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Texas Medical Center Hotels & Resorts for Couples Tonight [Nov 20 - Nov 21](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-11-20&endDate=2025-11-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 21 - Nov 22](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-11-21&endDate=2025-11-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Texas Medical Center Hotels & Resorts for Couples ![Outdoor pool, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/a994a387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/9235e98a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/026cb2a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/w3998h2667x2y0-ff5ca8a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Houston Medical Center/Museum District Texas Medical Center 9.2/10 Wonderful (1011) "Perfect location & amazing staff at the hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Orlando CA $181 CA $225 total includes taxes & fees Nov 22 - Nov 23 [](https://www.expedia.ca/Houston-Hotels-The-Westin-Houston-Medical-Center.h39618635.Hotel-Information) ![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/1000000/10000/6700/6636/w3835h2553x0y4-ca278b6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6700/6636/1c784498.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6700/6636/w3832h2556x3y0-eea8ad4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/10000/6700/6636/0a92087f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Houston Medical Center Hotel & Suites Texas Medical Center 8.4/10 Very good (453) "Staff was helpful in getting me back & forth to MD Anderson Cancer Hospital. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $151 CA $176 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Medical-Center-Hotel-And-Suites.h6636.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/70000000/69700000/69698900/69698896/w1024h666x0y9-70b4369d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/70000000/69700000/69698900/69698896/2faeb9dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/70000000/69700000/69698900/69698896/02f229c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/70000000/69700000/69698900/69698896/w904h683x60y0-0611a443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New fully furnished Med Center Apt By NRG Stadium Texas Medical Center 9.4/10 Exceptional (9) "Property was very clean, spacious, and convenient location. Host was very responsive and went the extra mile to make our stay enjoyable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffri CA $67 CA $255 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Houston-Hotels-Corporate-Apartment.h69698896.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/119000000/118680000/118677400/118677315/w1074h802x63y47-bc79f262.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/119000000/118680000/118677400/118677315/cbcbbf95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/119000000/118680000/118677400/118677315/6d516b15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/119000000/118680000/118677400/118677315/e7ad2a08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2BD/2BA Rolls-Royce Inspired City Highrise w/Rooftop Pool Texas Medical Center 9.2/10 Wonderful (13) CA $158 CA $254 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Houston-Hotels-2BD2BA-Rolls-Royce-Inspired-City-Highrise-WRooftop-Pool.h118677315.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/118000000/117370000/117365600/117365589/2c115dbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/118000000/117370000/117365600/117365589/724ed862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/118000000/117370000/117365600/117365589/60b4acd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/118000000/117370000/117365600/117365589/1a65bf9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NEW! The Brandõn: ★ Sleeps 8 ★ Garage ★ Near Medical Center & NRG Texas Medical Center CA $176 CA $682 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Houston-Hotels-The-Brandon-Sleeps-8-Garage-Near-Medical-Center-NRG.h117365589.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/aa7fafd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/c1fa2b90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/76e7278c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Quarters Hotel Downtown, Houston Downtown Houston 8.4/10 Very good (3899) "Hotel was beautiful, room was great for the price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sonya CA $109 CA $128 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/8cd20a4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/79245093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/w3840h2558x0y0-562426d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Americas-Houston Downtown Houston 9.4/10 Exceptional (1560) "Hotel was very nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra CA $194 CA $230 total includes taxes & fees Nov 29 - Nov 30 [](https://www.expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) ![City view](https://images.trvl-media.com/lodging/1000000/30000/20100/20005/3940b07d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/20100/20005/2ce18769.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/20100/20005/6b7ff15f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/20100/20005/a542eae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Houston Downtown Downtown Houston 9.2/10 Wonderful (1091) "Perfect place to stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yohlman CA $188 CA $229 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Houston-Hotels-Hyatt-Regency-Houston.h20005.Hotel-Information) ![City view from property](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/0c8e0486.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/7d7cd323.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor wedding](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/ebaa4874.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Whitehall Houston Downtown Houston 8.6/10 Excellent (1872) "Great stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anita CA $158 CA $185 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/13000000/12530000/12526500/12526454/a9738659.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12530000/12526500/12526454/23505ae1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/13000000/12530000/12526500/12526454/7e01b59f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/13000000/12530000/12526500/12526454/4f24c5ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Houston Downtown Downtown Houston 8.8/10 Excellent (1002) "Great location… clean and great breakfast variety. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David L Rojas CA $160 CA $187 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Houston-Hotels-Hampton-Inn-Houston-Downtown.h12526454.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-04&endDate=2025-12-05®ionId=6143504&adults=2&nearby_group=recreation&sort=RECOMMENDED&openPlayBack=true) ## Top Texas Medical Center Hotel Reviews ![The Royal Sonesta Houston Galleria](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960_y.jpg) ### The Royal Sonesta Houston Galleria 10/10 Excellent "Yes " [](https://expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) ![Club Quarters Hotel Downtown, Houston](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd_y.jpg) ### Club Quarters Hotel Downtown, Houston 10/10 Excellent "easy, clean and approximate to my project. however there was a ringing from next door that did not get resolved and made it a bit unfortunate sleeping wise as it went through the whole night." [](https://expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Houston Bush IAH South](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/0afb5a51_y.jpg) ### La Quinta Inn & Suites by Wyndham Houston Bush IAH South 10/10 Excellent "Everything was great! " [](https://expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-Bush-IAH-South.h165562.Hotel-Information) ![Heritage Place Houston Brookhollow](https://images.trvl-media.com/lodging/1000000/10000/6300/6298/90f3bec7_y.jpg) ### Heritage Place Houston Brookhollow 10/10 Excellent "Room and hotel was clean and well equipped! " [](https://expedia.ca/Houston-Hotels-Heritage-Place-Houston-Brookhollow.h6298.Hotel-Information) ![Magnolia Hotel Houston, A Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37_y.jpg) ### Magnolia Hotel Houston, A Tribute Portfolio Hotel 10/10 Excellent "There are AC issues. It was hot and I had minimal control." [](https://expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) ![Hilton Houston Plaza/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50_y.jpg) ### Hilton Houston Plaza/Medical Center 10/10 Excellent "Hilton is the best .. period. Everything excellent. Can’t say enough good things. Staff is 5 star. Highly recommend " [](https://expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![DoubleTree by Hilton Hotel Houston - Greenway Plaza](https://images.trvl-media.com/lodging/1000000/30000/20200/20177/682ca680_y.jpg) ### DoubleTree by Hilton Hotel Houston - Greenway Plaza 10/10 Excellent "Yes very clean and I even got a cookie I loved it" [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Houston-Greenway-Plaza.h20177.Hotel-Information) ![The Whitehall Houston](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056_y.jpg) ### The Whitehall Houston 10/10 Excellent "Great staff. Not a lot of dining options near property. Gym was ok too" [](https://expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information) ![Hilton Americas-Houston](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59_y.jpg) ### Hilton Americas-Houston 10/10 Excellent "The room was clean and the outside view was beautiful." [](https://expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) ## Frequently asked questions ### Why book your hotel for couples in Texas Medical Center with Expedia? > We think that traveling with your sweetheart should be a piece of cake, so if you're looking for a hotel for couples in Texas Medical Center at a competitive rate, Expedia has got you covered. Keep costs down and check in to a motel, or splurge and book an opulent hotel escape to treat the one you love the most. ### How can I find cheap hotels for couples in Texas Medical Center? > Expedia can help you look for cheap hotels for couples in Texas Medical Center. 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