Title: Hotels by Highgate Independent in Tenderloin from CA $251 | Expedia.ca [Tenderloin Travel Guide](https://expedia.ca/San-Francisco-Tenderloin.dx6203136)[Vacation Rentals in San Francisco](https://expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Tenderloin Car Rentals](https://expedia.ca/Car-Rentals-In-Tenderloin.d6203136.Car-Rental-Guide)[Tenderloin Vacations](https://expedia.ca/Tenderloin.d6203136.Destination-Travel-Guides) ![SanFrancisco_Tenderloin_6203136_5](https://images.trvl-media.com/place/6203136/7e4cdb86-4a34-4b4f-b261-0e9bed5cb2ba.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Highgate Independent in Tenderloin from CA $251 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 12 - Dec 13](https://www.expedia.ca/Hotel-Search?regionId=6203136&startDate=2025-12-12&endDate=2025-12-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6203136&startDate=2025-12-13&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6203136&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6203136&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Tenderloin Highgate Independent ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/575b2d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/ac2abcd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/9765cbda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach/ocean view](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/67096996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Caza Fisherman's Wharf [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information) Fisherman's Wharf 9.0/10 Wonderful (3826) "We stay here a lot, great place and safe." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Albert CA $160 CA $251 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information) ![City view](https://images.trvl-media.com/lodging/7000000/6280000/6272000/6271901/8ee09bb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6280000/6272000/6271901/a48a7017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 2 Queen Beds | View from room](https://images.trvl-media.com/lodging/7000000/6280000/6272000/6271901/24ee943e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily self-serve breakfast for a fee](https://images.trvl-media.com/lodging/7000000/6280000/6272000/6271901/51015b2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stanford Court San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-Stanford-Court-San-Francisco.h6271901.Hotel-Information) Downtown San Francisco 9.0/10 Wonderful (1335) "Great room, great view, always clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edward CA $178 CA $271 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/San-Francisco-Hotels-Stanford-Court-San-Francisco.h6271901.Hotel-Information) ![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/900/864/9c354d2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; local cuisine ](https://images.trvl-media.com/lodging/1000000/10000/900/864/0bb058ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/864/e5133fd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/864/28561d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Huntington Hotel [](https://www.expedia.ca/San-Francisco-Hotels-Huntington-Hotel.h864.Hotel-Information) Downtown San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-Huntington-Hotel.h864.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-27®ionId=6203136&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FTenderloin-San-Francisco-Hotels-Highgate-Independent.0-n6203136-0--bHighgateIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FTenderloin-San-Francisco-Hotels-Highgate-Independent.0-n6203136-0--bHighgateIndependent.Travel-Guide-Filter-Hotels) ## Top Tenderloin Hotel Reviews ![Best Western Plus Grosvenor Airport Hotel](https://images.trvl-media.com/lodging/1000000/10000/7700/7635/062e9dfe_y.jpg) ### Best Western Plus Grosvenor Airport Hotel 10/10 Excellent "Room was clean, and very comfortable. Airport shuttle was perfectly on time, and convenient " [](https://expedia.ca/San-Francisco-Hotels-Best-Western-Plus-Grosvenor-Airport-Hotel.h7635.Hotel-Information) ![DoubleTree by Hilton Hotel Berkeley Marina](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/ba0da8d5_y.jpg) ### DoubleTree by Hilton Hotel Berkeley Marina 10/10 Excellent "Staff was nice. Got a fresh warm chocolate chip cookie upon entrance. Clean room. Would recommend " [](https://expedia.ca/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information) ![FOUND Hotel Carlton, Nob Hill](https://images.trvl-media.com/lodging/104000000/103130000/103126600/103126565/818bb89d_y.jpg) ### FOUND Hotel Carlton, Nob Hill 10/10 Excellent "Staff are considerate, friendly, knowledgeable to name a few. They and the hotel make my stay comfortable and I feel safe. " [](https://expedia.ca/San-Francisco-Hotels-FOUND-Hotel-San-Francisco-Carlton.h103126565.Hotel-Information) ![Handlery Union Square Hotel](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "All of it was great! We will definitely stay again. " [](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ![Holiday Inn Golden Gateway by IHG](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f_y.jpg) ### Holiday Inn Golden Gateway by IHG 10/10 Excellent "Service was great!! Might be a bit noisy walls are thin but it's good. " [](https://expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information) ![Hyatt Place San Francisco Downtown](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/fc76649d_y.jpg) ### Hyatt Place San Francisco Downtown 10/10 Excellent "Room was small (hey, it's the city) but clean and well-appointed. Staff was great. Nice location close to the water." [](https://expedia.ca/San-Francisco-Hotels-Hyatt-Place-San-Francisco-Downtown.h31419890.Hotel-Information) ![Hilton San Francisco Financial District](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg) ### Hilton San Francisco Financial District 10/10 Excellent "Always great stay. Great staff, nice and clean rooms. " [](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information) ![LUMA Hotel San Francisco ](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/f72650f9_y.jpg) ### LUMA Hotel San Francisco 10/10 Excellent "Excellent location and room was spacious, clean and very comfortable bed. We will definitely stay here again! Great, friendly staff was an added bonus! " [](https://expedia.ca/San-Francisco-Hotels-LUMA-Hotel-San-Francisco.h70097106.Hotel-Information) ![Fairmont San Francisco](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4_y.jpg) ### Fairmont San Francisco 10/10 Excellent "Wonderful " [](https://expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information) ## Find out more about Tenderloin ## Tenderloin Hotels Guide Expedia.ca offers a selection of 4697 hotels in Tenderloin. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Tenderloin. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Tenderloin neighborhood you prefer. Go ahead. Enter your travel dates to view the best offers on hotel rooms in Tenderloin, San Francisco now! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [2 Star Hotels in Downtown San Francisco ](https://www.expedia.ca/2Star-Downtown-San-Francisco-San-Francisco-Hotels.s20-n6151902-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Downtown San Francisco ](https://www.expedia.ca/3Star-Downtown-San-Francisco-San-Francisco-Hotels.s30-n6151902-0.Travel-Guide-Filter-Hotels) - [Red Lion Hotels in Chinatown ](https://www.expedia.ca/Chinatown-San-Francisco-Hotels-Red-Lion.0-n6004910-0--bRedLion.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Downtown San Francisco ](https://www.expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels-Adults-Only-Resorts.0-n6151902-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [All Inclusive Resorts and in Downtown San Francisco ](https://www.expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels-All-Inclusive-Hotel.0-n6151902-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - 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