Title: Book the Best BOUTIQUE Hotels in Tenderloin in 2026 | Expedia.ca [Tenderloin Travel Guide](https://expedia.ca/San-Francisco-Tenderloin.dx6203136)[Vacation Rentals in San Francisco](https://expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Tenderloin Car Rentals](https://expedia.ca/Car-Rentals-In-Tenderloin.d6203136.Car-Rental-Guide)[Tenderloin Vacations](https://expedia.ca/Tenderloin.d6203136.Destination-Travel-Guides) ![SanFrancisco_Tenderloin_6203136_5](https://images.trvl-media.com/place/6203136/7e4cdb86-4a34-4b4f-b261-0e9bed5cb2ba.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Boutique Hotels in Tenderloin, CA from CA $175 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Tenderloin Boutique Hotels Tonight [Dec 30 - Dec 31](https://www.expedia.ca/Hotel-Search?regionId=6203136&startDate=2025-12-30&endDate=2025-12-31&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 31 - Jan 1](https://www.expedia.ca/Hotel-Search?regionId=6203136&startDate=2025-12-31&endDate=2026-01-01&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6203136&startDate=2026-01-02&endDate=2026-01-04&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6203136&startDate=2026-01-09&endDate=2026-01-11&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Tenderloin boutique hotels ![Game room](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/fd976170.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/91b70975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/a3393d8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/d2ac54ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zephyr San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information) Fisherman's Wharf 8.6/10 Excellent (2342) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah CA $171 CA $250 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/5bd0b8bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/4da6aa13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/7814d514.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/cb9fb20d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Berkeley City Club [](https://www.expedia.ca/Oakland-Hotels-Berkeley-City-Club.h1175858.Hotel-Information) Telegraph District 8.8/10 Excellent (697) "Wonderful, beautiful, old world hotel, right in the heart of bustling Berkeley. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peter CA $245 CA $282 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Oakland-Hotels-Berkeley-City-Club.h1175858.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/39d3931a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; seafood, alfresco dining ](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/ba1942b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/2d47f36f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Water view](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/7158d83b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Argonaut Hotel [](https://www.expedia.ca/San-Francisco-Hotels-Argonaut-Hotel-A-Noble-House-Hotel.h915510.Hotel-Information) Fisherman's Wharf 9.4/10 Exceptional (1216) "Absolutely amazing hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alicia CA $220 CA $317 total includes taxes & fees Jan 26 - Jan 27, 2026 [](https://www.expedia.ca/San-Francisco-Hotels-Argonaut-Hotel-A-Noble-House-Hotel.h915510.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/69c56718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/c438fd26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/5023ecf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/03417113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Clancy, Autograph Collection by Marriott [](https://www.expedia.ca/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information) Downtown San Francisco 9.2/10 Wonderful (1001) "Very professional staff! Central located walking distance to everything!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edmundo CA $225 CA $322 total includes taxes & fees Jan 10 - Jan 11, 2026 [](https://www.expedia.ca/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information) ![Room (Private Apartment)](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/7626c0a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/c731c06a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Private Apartment)](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/174738f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/7c771a5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Clift Royal Sonesta San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-The-Clift-Royal-Sonesta-San-Francisco.h21073.Hotel-Information) Union Square 9.2/10 Wonderful (1370) "clean, well appointed room in a good location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susanna CA $183 CA $269 total includes taxes & fees Jan 16 - Jan 17, 2026 [](https://www.expedia.ca/San-Francisco-Hotels-The-Clift-Royal-Sonesta-San-Francisco.h21073.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/900/876/bf356ca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, hypo-allergenic bedding, down comforters](https://images.trvl-media.com/lodging/1000000/10000/900/876/w3837h2560x3y0-673688de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, Corner](https://images.trvl-media.com/lodging/1000000/10000/900/876/ac9e0336.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/876/e25769c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Warwick San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-Warwick-San-Francisco.h876.Hotel-Information) Union Square 8.2/10 Very good (1003) "Room was very nice! Staff was wonderful! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian CA $144 CA $219 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Francisco-Hotels-Warwick-San-Francisco.h876.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/a6ba3784.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/57aa38c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/f8220459.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/33ce2394.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Marker Union Square San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-The-Marker-San-Francisco.h15769.Hotel-Information) Union Square 9.0/10 Wonderful (1132) "The staff was so fabulous, the hotel is gorgeous, and we are already having the best time!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Faith CA $204 CA $240 total includes taxes & fees Jan 29 - Jan 30, 2026 [](https://www.expedia.ca/San-Francisco-Hotels-The-Marker-San-Francisco.h15769.Hotel-Information) ![Suite, Multiple Beds (The Two Bedroom)](https://images.trvl-media.com/lodging/1000000/50000/49800/49777/bf019538.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/49800/49777/6d934a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/1000000/50000/49800/49777/3d698b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Accessible](https://images.trvl-media.com/lodging/1000000/50000/49800/49777/9fb30810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palihotel San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-Palihotel-San-Francisco.h49777.Hotel-Information) Union Square 8.4/10 Very good (632) "Great vibe here and the rooms and so cute . Excellent bar and bar staff . " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lana CA $119 CA $175 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/San-Francisco-Hotels-Palihotel-San-Francisco.h49777.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/400/384/631bdce2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/1000000/10000/400/384/df9b3b05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/400/384/8bc35411.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Skyline Waterfront Penthouse) | View from room](https://images.trvl-media.com/lodging/1000000/10000/400/384/1b7910ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harbor Court Hotel [](https://www.expedia.ca/San-Francisco-Hotels-Harbor-Court-Hotel.h384.Hotel-Information) Downtown San Francisco 9.0/10 Wonderful (1005) "Great location, vintage place & walkable everywhere" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ROBERT CA $190 CA $287 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/San-Francisco-Hotels-Harbor-Court-Hotel.h384.Hotel-Information) ![City view](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/d044cc49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/111bcf12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/67a43361.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Union Square Deluxe King Bed](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/b4524bad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Taj Campton Place [](https://www.expedia.ca/San-Francisco-Hotels-Taj-Campton-Place.h23383.Hotel-Information) Union Square 9.2/10 Wonderful (1000) "Wonderful Staff and hospitality." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel CA $243 CA $334 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Francisco-Hotels-Taj-Campton-Place.h23383.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-13&endDate=2026-01-14®ionId=6203136&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top Tenderloin Hotel Reviews ![Hyatt Centric Fisherman's Wharf San Francisco](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3_y.jpg) ### Hyatt Centric Fisherman's Wharf San Francisco 10/10 Excellent "Everything was amazing thank you!! Spencer Potter" [](https://expedia.ca/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information) ![Handlery Union Square Hotel](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "friendly staff and spacious rooms. only complaint is my bf (ex bf now) went through my phone during our stay and now are broken up but that has nothing to do with the hotel lol other than that i would 10/10 reccomend " [](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ![Fairmont San Francisco](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4_y.jpg) ### Fairmont San Francisco 10/10 Excellent "YES!" [](https://expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information) ![The Westin St. Francis San Francisco on Union Square](https://images.trvl-media.com/lodging/1000000/30000/26800/26760/99dd32f8_y.jpg) ### The Westin St. Francis San Francisco on Union Square 10/10 Excellent "Everything was good! " [](https://expedia.ca/San-Francisco-Hotels-The-Westin-St-Francis-San-Francisco-On-Union-Square.h26760.Hotel-Information) ![Hotel Riu Plaza Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg) ### Hotel Riu Plaza Fisherman's Wharf 10/10 Excellent "Good location for travel around the city. Breakfast was great. " [](https://expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![InterContinental San Francisco by IHG](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/5800bbe5_y.jpg) ### InterContinental San Francisco by IHG 10/10 Excellent "I didn't get the free breakfast. " [](https://expedia.ca/San-Francisco-Hotels-InterContinental-San-Francisco.h1766605.Hotel-Information) ![Chancellor Hotel on Union Square](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c_y.jpg) ### Chancellor Hotel on Union Square 10/10 Excellent "Conveniently located " [](https://expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information) ![Hilton San Francisco Airport Bayfront](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/7b6b8635_y.jpg) ### Hilton San Francisco Airport Bayfront 10/10 Excellent "Great service " [](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Airport-Bayfront.h12345.Hotel-Information) ![Hotel Zoe Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/21cb8d87_y.jpg) ### Hotel Zoe Fisherman's Wharf 10/10 Excellent "Was hard to tell when I first checked in the power was off, (I Know that was not the hotels' fault) my second impression in the morning was good. Hotel looked to be clean, staff was very accommodating and helpful. " [](https://expedia.ca/San-Francisco-Hotels-Hotel-Zoe-Fishermans-Wharf.h3552.Hotel-Information) ## Frequently asked questions ### What's there to see and do in Tenderloin? ## Explore a world of travel with Expedia - Lodging - More ways to book - [Adults Only Resorts & in Downtown San Francisco ](https://www.expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels-Adults-Only-Resorts.0-n6151902-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [All Inclusive Resorts and in Downtown San Francisco ](https://www.expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels-All-Inclusive-Hotel.0-n6151902-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Downtown San Francisco ](https://www.expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels-Beach-Hotel.0-n6151902-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Downtown San Francisco ](https://www.expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels-Boutique-Hotel.0-n6151902-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - 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[Scuba Diving Hotels in Downtown San Francisco ](https://www.expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels-Scuba-Diving-Vacations.0-n6151902-0-tscubadivingvacations.Travel-Guide-Filter-Hotels) - [Shopping Hotels in Downtown San Francisco ](https://www.expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels-Shopping-Hotel.0-n6151902-0-tShoppingHotel.Travel-Guide-Filter-Hotels) - [Ski Hotels in Downtown San Francisco ](https://www.expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels-Ski-Hotel.0-n6151902-0-tSkiHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Downtown San Francisco ](https://www.expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels-Spa-Hotel.0-n6151902-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Downtown San Francisco ](https://www.expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels-Waterpark-Hotels.0-n6151902-0-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Downtown San Francisco ](https://www.expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels-Wedding-Hotels.0-n6151902-0-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Winery Hotels in Downtown San Francisco ](https://www.expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels-Winery-Hotel.0-n6151902-0-tWineryHotel.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Fisherman's Wharf ](https://www.expedia.ca/Fishermans-Wharf-San-Francisco-Hotels-Adults-Only-Resorts.0-n800128-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [All Inclusive Resorts and in Fisherman's Wharf ](https://www.expedia.ca/Fishermans-Wharf-San-Francisco-Hotels-All-Inclusive-Hotel.0-n800128-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Fisherman's Wharf ](https://www.expedia.ca/Fishermans-Wharf-San-Francisco-Hotels-Beach-Hotel.0-n800128-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Business Hotels in Fisherman's Wharf ](https://www.expedia.ca/Fishermans-Wharf-San-Francisco-Hotels-Business-Hotel.0-n800128-0-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in Fisherman's Wharf ](https://www.expedia.ca/Fishermans-Wharf-San-Francisco-Hotels-Casino-Hotel.0-n800128-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - 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