St. Charles Vacation Rentals
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check prices for these dates
Next weekend
In two weeks
In one month
In two months
Browse Select St. Charles Vacation Homes

St. Charles 1860's Gem - Sleeps 6!
St. Charles 1860's Gem - Sleeps 6!
9.8 out of 10, Exceptional, (118)
The price is CA $136
CA $311 total
includes taxes & fees
Aug 25 - Aug 26

Beautiful, Rehabbed Unit in Shaw Community 4228a
Beautiful, Rehabbed Unit in Shaw Community 4228a
7.6 out of 10, Good, (17)
The price is CA $62
CA $367 total
includes taxes & fees
Aug 17 - Aug 18

Charming 1-bedroom home in the heart of The Hill!
Charming 1-bedroom home in the heart of The Hill!
10.0 out of 10, Exceptional, (5)
The price is CA $158
CA $241 total
includes taxes & fees
Aug 20 - Aug 21

HOT TUB! Fishermans lake house retreat
HOT TUB! Fishermans lake house retreat
6.8 out of 10, (11)
The price is CA $202
CA $369 total
includes taxes & fees
Aug 20 - Aug 21

St Louis Townhome-Perfect for Groups!
St Louis Townhome-Perfect for Groups!
8.0 out of 10, Very good, (52)
The price is CA $81
CA $329 total
includes taxes & fees
Aug 17 - Aug 18

Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway
Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway
9.6 out of 10, Exceptional, (44)
The price is CA $178
CA $455 total
includes taxes & fees
Aug 20 - Aug 21

Entire Dogtown House near Zoo, Forest Park and Wash U
Entire Dogtown House near Zoo, Forest Park and Wash U
10.0 out of 10, Exceptional, (208)

Modern House with Terrace Near Forest Park
Modern House with Terrace Near Forest Park
9.0 out of 10, Wonderful, (11)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top St. Charles Hotel Reviews

Pear Tree Inn St. Louis Near Union Station
10/10 Excellent
Find out more about St. Charles
Find out more about St. Charles
St. Charles Vacation Homes information
Number of reviews | 1,247 |
---|---|
Accommodation | 739 Vacation Homes |
Lowest Price | CA $62 |
Highest Price | CA $379 |
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Popular Destinations
- Vacation Homes in Grafton
- Vacation Homes in Old Monroe
- Vacation Homes in Hamburg
- Vacation Homes in Defiance
- Vacation Homes in Cottleville
- Vacation Homes in Weldon Spring
- Vacation Homes in O'Fallon
- Vacation Homes in Harvester
- Vacation Homes in St. Peters
- Vacation Homes in Earth City
- Vacation Homes in West Alton
- Vacation Homes in Weldon Spring Heights
- Vacation Homes in Florissant
- Vacation Homes in Bridgeton
- Vacation Homes in Maryland Heights
- Vacation Homes in Chesterfield
Top Vacation Homes in Other Destinations
More Accommodation Types in St. Charles
- Apartments in St. Charles
- Chalets in St. Charles
- Condo Rentals in St. Charles
- Cottages in St. Charles
- Cabin Rentals in St. Charles
- Motels in St. Charles
- Aparthotels in St. Charles
- B&B in St. Charles
- Guest Houses in St. Charles
- Villas in St. Charles
- RV Parks in St. Charles
- Inns in St. Charles
- Lodges in St. Charles
- Farmstay in St. Charles
- Hostels in St. Charles
- Resorts in St. Charles
- Townhomes in St. Charles
- Hotels
All Accommodation Types
Be inspired: Top Vacation Homes destinations in 2025
- Orlando Vacation Homes
- Florida Vacation Homes
- Kissimmee Vacation Homes
- Hawaii Vacation Homes
- Costa Rica Vacation Homes
- Walt Disney World® Vacation Homes
- Palm Springs Vacation Homes
- Naples Vacation Homes
- Victoria Vacation Homes
- Kelowna Vacation Homes
- Toronto Vacation Homes
- Las Vegas Vacation Homes
- Vancouver Vacation Homes
- Mexico Vacation Homes
- Phoenix Vacation Homes
- Fort Lauderdale Vacation Homes
- Davenport Vacation Homes
- Myrtle Beach Vacation Homes
- Los Angeles Vacation Homes
- Cape Coral Vacation Homes
More ways to book
Expedia's Latest Trends
Hotels
- Beaches Turks & Caicos - ALL INCLUSIVE
- Travelodge by Wyndham Port Elgin
- Quality Inn & Suites Downtown
- Portland Cheap Hotels
- Le Meridien Dubai Hotel & Conference Centre
- Hyatt Place Toronto - Brampton
- Humble House Hotel Taipei, Curio Collection by Hilton
- Best Hotels in Stewart
- Quality Inn & Suites Garden of the Gulf
- Borgata Hotel Casino & Spa
- Chelsea Hotel, Toronto
Flights
Packages
General