Title: Book the Best BUSINESS Hotels in St. Charles Historic District in 2025 | Expedia.ca [St. Charles Historic District Travel Guide](https://expedia.ca/St-Louis-St-Charles-Historic-District.dx6295406)[Vacation Rentals in St. Louis](https://expedia.ca/St-Louis-Vacation-Rentals.d178309.Travel-Guide-VacationRentals)[Flights to St. Louis](https://expedia.ca/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.ca/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[St. Charles Historic District Car Rentals](https://expedia.ca/Car-Rentals-In-St-Charles-Historic-District.d6295406.Car-Rental-Guide)[St. Charles Historic District Vacations](https://expedia.ca/St-Charles-Historic-District.d6295406.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/ce317b836679e529e2a8b73bd1814ebb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Geraldine Soh # Find Business Hotels in St. Charles Historic District, MO from CA $138 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on St. Charles Historic District Business Hotels Tonight [Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6295406&startDate=2025-11-01&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Nov 2 - Nov 3](https://www.expedia.ca/Hotel-Search?regionId=6295406&startDate=2025-11-02&endDate=2025-11-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6295406&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6295406&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top St. Charles Historic District Business Hotels ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/529fe0ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/0b058bce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/001d26f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/0ac0729a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, St. Charles Historic District St. Charles Historic District 9.4/10 Exceptional (1002) "It was a really nice hotel and in a great area to walk around." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) georgia CA $148 CA $170 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/fcf144f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/9bdbe023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/a059af27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel Downtown St. Louis 8.8/10 Excellent (1082) "Will definitely stay again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JASON CA $123 CA $146 total includes taxes & fees Nov 8 - Nov 9 [](https://www.expedia.ca/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/4d0e3d47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/1ed98bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/68c9f9ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn St. Louis Airport St. Ann 9.4/10 Exceptional (2732) "Great place to stay!! Excellent staff too!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian CA $126 CA $148 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) ![Ballroom](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub | Jetted tub](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/1893bab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/9fbd251c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/035dee6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Wildwood Hotel Wildwood 9.2/10 Wonderful (1597) "We enjoyed our stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $124 CA $149 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/a7d1479b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, a heated pool, open 10:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/fd2b191b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/13e26dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clayton Plaza Hotel & Extended Stay Clayton 8.8/10 Excellent (2979) "Clean room; very nice staff; reasonable rates." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Malcolm CA $146 CA $171 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/446bd1a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/c85b5876.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/cb7cc1f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham Fenton 8.0/10 Very good (1023) "Good hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly CA $119 CA $138 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/3e0ca2c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/cff3dc72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/cebe4fcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/f9bf260b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express St. Louis West - O'Fallon by IHG O'Fallon 8.6/10 Excellent (811) "Clean, well maintained hotel. Friendly staff, great breakfast. Close to shopping and restaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theresa CA $133 CA $157 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-St-Louis-West-OFallon.h1206489.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/50700/50618/dc7136af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/60000/50700/50618/ecdf92ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50700/50618/c4174534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/60000/50700/50618/c60f07ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus St. Louis Airport Hotel Woodson Terrace 9.2/10 Wonderful (1007) "It was great stay, nice people!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) EISUKE CA $142 CA $176 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/St-Louis-Hotels-Best-Western-Plus-St-Louis-Airport-Hotel.h50618.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/0c098574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/cb1b5cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rodeo Junior Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/b33425c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hollywood Casino & Hotel St. Louis Maryland Heights 8.4/10 Very good (2203) "Great stay would recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ross CA $134 CA $177 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/fe8445aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/w2897h2195x0y8-cdf51e05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/10a24838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/db6ee37f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Moonrise Hotel Delmar Loop 9.0/10 Wonderful (1904) "Always love staying at the moonrise." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jarrod CA $176 CA $210 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-16&endDate=2025-11-17®ionId=6295406&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top St. Charles Historic District Hotel Reviews ![Pear Tree Inn St. Louis Airport](//images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2_y.jpg) ### Pear Tree Inn St. Louis Airport 10/10 Excellent "Hotel was clean and nice. Breakfast was fine. They have make your own waffles, sausage and bacon, and mass produced eggs. The shuttle service is reliable." [](https://expedia.ca/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) ![Pear Tree Inn St. Louis Near Union Station](//images.trvl-media.com/lodging/1000000/30000/26600/26572/0bb9dbf3_y.jpg) ### Pear Tree Inn St. Louis Near Union Station 10/10 Excellent "Staff was very courteous 💕rom was very clean💕" [](https://expedia.ca/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Near-Union-Station.h26572.Hotel-Information) ![Clayton Plaza Hotel & Extended Stay](//images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd_y.jpg) ### Clayton Plaza Hotel & Extended Stay 10/10 Excellent "Stayed here many times. I especially love the breakfast." [](https://expedia.ca/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) ![The Cheshire](//images.trvl-media.com/lodging/1000000/30000/26100/26061/b6ec06de_y.jpg) ### The Cheshire 10/10 Excellent "Breakfast was great, bar was unique," [](https://expedia.ca/St-Louis-Hotels-The-Cheshire.h26061.Hotel-Information) ![Country Inn & Suites by Radisson, St. Charles Historic District](//images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/529fe0ff_y.jpg) ### Country Inn & Suites by Radisson, St. Charles Historic District 10/10 Excellent "The staff were very welcoming & helpful. The property was clean & comfortable. " [](https://expedia.ca/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information) ![Forest Park Hotel by MDR](//images.trvl-media.com/lodging/1000000/30000/22300/22298/21d70af8_y.jpg) ### Forest Park Hotel by MDR 10/10 Excellent "The room was nice and clean although the queen size bed is not that big but overall I had a good experience and will stay again." [](https://expedia.ca/St-Louis-Hotels-Holiday-Inn-St-Louis-Forest-Park.h22298.Hotel-Information) ![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](//images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c_y.jpg) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham 10/10 Excellent "New name but holding to Drury's ways. Staff was friendly, room was clean. I didn't stop by to eat breakfast. I do miss the popcorn that Drury offered. " [](https://expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) ![Drury Inn & Suites St. Louis Union Station](//images.trvl-media.com/lodging/1000000/40000/37700/37651/151222b4_y.jpg) ### Drury Inn & Suites St. Louis Union Station 10/10 Excellent "Staff was exremely hlpful and friendly. Took time to anseer my silly questions. Even held our luggage after check out so we could do so.e sight seeing before our train left." [](https://expedia.ca/St-Louis-Hotels-Drury-Inn-St-Louis-At-Union-Station.h37651.Hotel-Information) ![Renaissance St. Louis Airport Hotel](//images.trvl-media.com/lodging/1000000/10000/4700/4672/879431a1_y.jpg) ### Renaissance St. Louis Airport Hotel 10/10 Excellent "Staff was excellent " [](https://expedia.ca/St-Louis-Hotels-Renaissance-St-Louis-Airport-Hotel.h4672.Hotel-Information) ## Frequently asked questions ### Why book your business-friendly hotel in St. Charles Historic District with Expedia? > At Expedia, our top task is to help you track down the perfect stay at the right price. From 5-star corporate-friendly properties to affordable motels filled with all the amenities you need, you'll have your next work trip organized in a few simple clicks. ### How can I find cheap business-friendly hotels in St. Charles Historic District? > When you're travelling for work in St. Charles Historic District, our "business friendly" filter will help you find the perfect hotel. From included breakfast and free WiFi to workspaces and meeting rooms, they have the amenities you need to get down to business. Another useful tip? 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