Title: Book the Best BUSINESS Hotels in Southwest Oklahoma in 2026 | Expedia.ca [Southwest Oklahoma Travel Guide](https://expedia.ca/Southwest-Oklahoma.dx6058698)[Hotels in Southwest Oklahoma](https://expedia.ca/Southwest-Oklahoma-Hotels.d6058698.Travel-Guide-Hotels)[Vacation Rentals in Southwest Oklahoma](https://expedia.ca/Southwest-Oklahoma-Vacation-Rentals.d6058698.Travel-Guide-VacationRentals)[Flights to Southwest Oklahoma](https://expedia.ca/Cheap-Flights-To-Southwest-Oklahoma.d6058698.Travel-Guide-Flights)[Southwest Oklahoma Car Rentals](https://expedia.ca/Car-Rentals-In-Southwest-Oklahoma.d6058698.Car-Rental-Guide)[Southwest Oklahoma Vacation Packages](https://expedia.ca/Southwest-Oklahoma.d6058698.Destination-Travel-Guides) ![Dog Run Hollow trail hike.](https://images.trvl-media.com/place/553248635976193584/ccad0a9b-8b4b-4177-99fe-04ef2ab31abe.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Katie Irvin ![](https://images.trvl-media.com/place/553248635976193584/ccad0a9b-8b4b-4177-99fe-04ef2ab31abe.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southwest Oklahoma Business Hotels Tonight [Jan 23 - Jan 24](https://www.expedia.ca/Hotel-Search?regionId=6058698&startDate=2026-01-23&endDate=2026-01-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Jan 24 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6058698&startDate=2026-01-24&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6058698&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6058698&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Southwest Oklahoma business-friendly hotels ![Indoor pool](https://images.trvl-media.com/lodging/1000000/980000/972800/972726/1e60806b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/972800/972726/edd72b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/980000/972800/972726/8c4ee56e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/980000/972800/972726/27263150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Sayre [](https://www.expedia.ca/Elk-City-Hotels-AmericInn-By-Wyndham-Sayre.h972726.Hotel-Information) Sayre 8.6/10 Excellent (563 reviews) "Nice environment and the staff was very helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barry CA $98 CA $113 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Elk-City-Hotels-AmericInn-By-Wyndham-Sayre.h972726.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/75000000/74840000/74838500/74838452/ad49becc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/75000000/74840000/74838500/74838452/4dd57ef1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 2 Queen Beds | Living area](https://images.trvl-media.com/lodging/75000000/74840000/74838500/74838452/334bb0a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/75000000/74840000/74838500/74838452/dde407e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Weatherford [](https://www.expedia.ca/Weatherford-Hotels-Home2-Suites-By-Hilton-Weatherford.h74838452.Hotel-Information) Weatherford 9.4/10 Exceptional (295 reviews) "Staff was great and rooms were clean. Would stay there, again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) erica CA $101 CA $114 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Weatherford-Hotels-Home2-Suites-By-Hilton-Weatherford.h74838452.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/8000000/7950000/7946700/7946642/ac753e6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7950000/7946700/7946642/7fb73a6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7950000/7946700/7946642/e6eb5371.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/8000000/7950000/7946700/7946642/6982bc6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Clinton Historic Route 66 [](https://www.expedia.ca/Elk-City-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Clinton-Historic-Route-66.h7946642.Hotel-Information) Clinton 9.2/10 Wonderful (1,003 reviews) "We stay every couple of months for visiting parents. Great place to stay. Very nice staff. Good breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randy CA $111 CA $127 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Elk-City-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Clinton-Historic-Route-66.h7946642.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/7000000/6100000/6098300/6098236/41b1bcb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/7000000/6100000/6098300/6098236/70af146b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6100000/6098300/6098236/4f5ed328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/7000000/6100000/6098300/6098236/f8bc59cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apache Casino Hotel [](https://www.expedia.ca/Lawton-Hotels-Apache-Casino-Hotel.h6098236.Hotel-Information) Lawton 9.0/10 Wonderful (1,008 reviews) "Very very nice hotel. Very clean comfy beds" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christy CA $110 CA $128 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Lawton-Hotels-Apache-Casino-Hotel.h6098236.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/850000/849500/849409/749d5ccf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/850000/849500/849409/9a221112.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, individually decorated](https://images.trvl-media.com/lodging/1000000/850000/849500/849409/53183b94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/849500/849409/54885e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lucille's Hotel, Restaurant, & Bar [](https://www.expedia.ca/Weatherford-Hotels-Lucilles-Hotel.h849409.Hotel-Information) Weatherford 9.0/10 Wonderful (485 reviews) "Best place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Faye CA $124 CA $141 total includes taxes & fees Jan 24 - Jan 25 [](https://www.expedia.ca/Weatherford-Hotels-Lucilles-Hotel.h849409.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5200/5103/w3837h2557x3y3-76e28d2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5200/5103/w3837h2557x3y3-562a44dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/5200/5103/w3837h2557x3y3-6d21b14c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 10:00 AM to 10 PM, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/5200/5103/e3ac81eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Weatherford [](https://www.expedia.ca/Weatherford-Hotels-Best-Western-Plus-Weatherford.h5103.Hotel-Information) Weatherford 9.0/10 Wonderful (1,000 reviews) "Great theme and atmosphere." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theodore J CA $112 CA $127 total includes taxes & fees Jan 31 - Feb 1 [](https://www.expedia.ca/Weatherford-Hotels-Best-Western-Plus-Weatherford.h5103.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/6000000/5470000/5464500/5464494/68cc7656.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5470000/5464500/5464494/8037e8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/6000000/5470000/5464500/5464494/f85f56b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/6000000/5470000/5464500/5464494/e0f70f6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Elk City by IHG [](https://www.expedia.ca/Elk-City-Hotels-Holiday-Inn-Express-Hotel-Suites-Elk-City.h5464494.Hotel-Information) Elk City 9.2/10 Wonderful (651 reviews) "Clean room, decent breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Virginia CA $117 CA $134 total includes taxes & fees Feb 20 - Feb 21 [](https://www.expedia.ca/Elk-City-Hotels-Holiday-Inn-Express-Hotel-Suites-Elk-City.h5464494.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/17000000/16630000/16630000/16629988/685ea5b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/17000000/16630000/16630000/16629988/9f261e62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/17000000/16630000/16630000/16629988/f36a1080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/17000000/16630000/16630000/16629988/f1dffee8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Executive Residency Elk City [](https://www.expedia.ca/Elk-City-Hotels-Best-Western-Plus-Executive-Residency-Elk-City.h16629988.Hotel-Information) Elk City 8.6/10 Excellent (780 reviews) "The staff was very professional." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terry CA $117 CA $134 total includes taxes & fees Jan 24 - Jan 25 [](https://www.expedia.ca/Elk-City-Hotels-Best-Western-Plus-Executive-Residency-Elk-City.h16629988.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/3000000/2860000/2858600/2858543/86f4e796.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2860000/2858600/2858543/bb04fcd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2860000/2858600/2858543/de15c090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2860000/2858600/2858543/330c1560.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Weatherford [](https://www.expedia.ca/Weatherford-Hotels-Fairfield-Inn-Suites-By-Marriott-Weatherford.h2858543.Hotel-Information) Weatherford 9.0/10 Wonderful (694 reviews) "Clean, quiet, & comfy, a pleasant staff and a great breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen CA $130 CA $147 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Weatherford-Hotels-Fairfield-Inn-Suites-By-Marriott-Weatherford.h2858543.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/7000000/6120000/6113400/6113379/3904ac57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6120000/6113400/6113379/a662d4f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free full breakfast](https://images.trvl-media.com/lodging/7000000/6120000/6113400/6113379/af9241ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6120000/6113400/6113379/18bf06ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Elk City Route 66 [](https://www.expedia.ca/Elk-City-Hotels-Sleep-Inn-Suites.h6113379.Hotel-Information) Elk City 8.2/10 Very good (1,004 reviews) "Comfy bed and great breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $87 CA $100 total includes taxes & fees Feb 12 - Feb 13 [](https://www.expedia.ca/Elk-City-Hotels-Sleep-Inn-Suites.h6113379.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-06&endDate=2026-02-07®ionId=6058698&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Southwest Oklahoma Hotel Reviews ![La Quinta Inn & Suites by Wyndham Clinton Historic Route 66](https://images.trvl-media.com/lodging/8000000/7950000/7946700/7946642/ac753e6f_y.jpg) ### La Quinta Inn & Suites by Wyndham Clinton Historic Route 66 10/10 Excellent "We stay every couple of months for visiting parents. Great place to stay. Very nice staff. Good breakfast." [](https://expedia.ca/Elk-City-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Clinton-Historic-Route-66.h7946642.Hotel-Information) ![Apache Casino Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6098300/6098236/55cedabd_y.jpg) ### Apache Casino Hotel 10/10 Excellent "Staff is very polite and accommodating. Room was clean and comfortable. " [](https://expedia.ca/Lawton-Hotels-Apache-Casino-Hotel.h6098236.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Weatherford OK](https://images.trvl-media.com/lodging/16000000/15750000/15740400/15740369/b24e30bd_y.jpg) ### La Quinta Inn & Suites by Wyndham Weatherford OK 10/10 Excellent "Front desk was amazing " [](https://expedia.ca/Weatherford-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Weatherford-OK.h15740369.Hotel-Information) ![MySuites Lawton](https://images.trvl-media.com/lodging/1000000/290000/284400/284349/e4bf1ff2_y.jpg) ### MySuites Lawton 10/10 Excellent "Overall a good experience, breakfast was excellent " [](https://expedia.ca/Lawton-Hotels-MySuites-Lawton.h284349.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Lawton / Fort Sill](https://images.trvl-media.com/lodging/3000000/2490000/2487600/2487545/2e0f809d_y.jpg) ### La Quinta Inn & Suites by Wyndham Lawton / Fort Sill 10/10 Excellent "Room clean. Nice property " [](https://expedia.ca/Lawton-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Lawton-Fort-Sill.h2487545.Hotel-Information) ![Comfort Suites Lawton Near Fort Sill](https://images.trvl-media.com/lodging/3000000/2520000/2512400/2512383/e9d84054_y.jpg) ### Comfort Suites Lawton Near Fort Sill 10/10 Excellent "Room was spotless. Staff was helpful. Nice hot showers. Close enough to all restaurants and Wichita Mountains. I enjoyed my stay." [](https://expedia.ca/Lawton-Hotels-Comfort-Suites-Lawton-Near-Fort-Sill.h2512383.Hotel-Information) ![Quality Inn Chickasha](https://images.trvl-media.com/lodging/1000000/10000/1200/1106/5b460a58_y.jpg) ### Quality Inn Chickasha 10/10 Excellent "Everything was good " [](https://expedia.ca/Chickasha-Hotels-Chickasha-Inn-Convention-Center.h1106.Hotel-Information) ![Sleep Inn & Suites Lawton Near Fort Sill](https://images.trvl-media.com/lodging/3000000/2750000/2745500/2745500/72f97392_y.jpg) ### Sleep Inn & Suites Lawton Near Fort Sill 10/10 Excellent "We were in town to visit our son and his family who live in Lawton. This was a very nice place and convenient." [](https://expedia.ca/Lawton-Hotels-Sleep-Inn-Suites-Lawton-Near-Fort-Sill.h2745500.Hotel-Information) ![Extended Stay America Suites Lawton Fort Sill](https://images.trvl-media.com/lodging/4000000/3880000/3873300/3873257/86e369f7_y.jpg) ### Extended Stay America Suites Lawton Fort Sill 10/10 Excellent "No coffee or breakfast offered, indicated supply shortage" [](https://expedia.ca/Lawton-Hotels-Extended-Stay-America-Suites-Lawton-Fort-Sill.h3873257.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Southwest Oklahoma cost? ### What are the best business-friendly hotels in Southwest Oklahoma? ### How many business-friendly hotels are there in Southwest Oklahoma? ### What are the best cheap business-friendly hotels in Southwest Oklahoma? ### Are there any family-friendly hotels in Southwest Oklahoma that are also business friendly? ### Why book your business-friendly hotel in Southwest Oklahoma with Expedia? ### How can I find cheap business-friendly hotels in Southwest Oklahoma? ### What is there to do in Southwest Oklahoma near my business-friendly hotel? ## Explore a world of travel with Expedia - 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