Title: Hotels by Drury Inn & Suites in Southwest Illinois from CA $146 | Expedia.ca [Southwest Illinois Travel Guide](https://expedia.ca/Southwest-Illinois.dx6058943)[Hotels in Southwest Illinois](https://expedia.ca/Southwest-Illinois-Hotels.d6058943.Travel-Guide-Hotels)[Vacation Rentals in Southwest Illinois](https://expedia.ca/Southwest-Illinois-Vacation-Rentals.d6058943.Travel-Guide-VacationRentals)[Flights to Southwest Illinois](https://expedia.ca/Cheap-Flights-To-Southwest-Illinois.d6058943.Travel-Guide-Flights)[Southwest Illinois Car Rentals](https://expedia.ca/Car-Rentals-In-Southwest-Illinois.d6058943.Car-Rental-Guide)[Southwest Illinois Vacation Packages](https://expedia.ca/Southwest-Illinois.d6058943.Destination-Travel-Guides) ![One of the northermost cypress swamps in the States, the Cache River State Natural area is home to Cypress trees that are over 1000 years old. This is shot from the hiking trail (no boat), and was just a sampling of the scores of cypress trees all around. #treetrove](https://images.trvl-media.com/place/553248634983556233/b4c981e9-72cf-4dc0-8b97-270e21fe73c6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Carl Anderson # Find Hotels by Drury Inn & Suites in Southwest Illinois from CA $146 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6058943&startDate=2025-12-13&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=6058943&startDate=2025-12-14&endDate=2025-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6058943&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6058943&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southwest Illinois Drury Inn & Suites ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/b6b6aa46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/3040b640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/a5bed563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Mt. Vernon [](https://www.expedia.ca/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) Mount Vernon 9.6/10 Exceptional (1571) "Great place to stay. Check in is easy and the hotel people are very nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Duane CA $129 CA $146 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/d2bc121f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/83d996f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/d789f3f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/2e5b0061.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis O'Fallon, IL [](https://www.expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-OFallon.h1544028.Hotel-Information) O'Fallon 9.6/10 Exceptional (1005) "Excellent location, clean and spacious room, great morning breakfast with numerous choices and of course helpful and pleasant staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $140 CA $163 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-OFallon.h1544028.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/c56c0460.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/91646e6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/f4bb5039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/4ece7c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis Fairview Heights [](https://www.expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) Fairview Heights 9.2/10 Wonderful (1002) "Staff was very nice and the room was clean and comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah CA $129 CA $146 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-28&endDate=2025-12-29®ionId=6058943&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouthwest-Illinois-Hotels-Drury-Inn-Suites.0-0-d6058943--bDruryInnSuites.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouthwest-Illinois-Hotels-Drury-Inn-Suites.0-0-d6058943--bDruryInnSuites.Travel-Guide-Filter-Hotels) ## Top Southwest Illinois Hotel Reviews ![Days Inn by Wyndham Collinsville/St. Louis](https://images.trvl-media.com/lodging/1000000/50000/42100/42033/e64aa27b_y.jpg) ### Days Inn by Wyndham Collinsville/St. Louis 10/10 Excellent "My dog loved it. Great staff !!!" [](https://expedia.ca/Collinsville-Hotels-Days-Inn-By-Wyndham-Collinsville.h42033.Hotel-Information) ![Drury Inn & Suites Marion](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/a8315e37_y.jpg) ### Drury Inn & Suites Marion 10/10 Excellent "Breakfast was very good. Dinner was fair." [](https://expedia.ca/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information) ![Quality Inn & Suites near St. Louis and I-255](https://images.trvl-media.com/lodging/1000000/220000/218600/218540/d0ef6db8_y.jpg) ### Quality Inn & Suites near St. Louis and I-255 10/10 Excellent "Great value." [](https://expedia.ca/Collinsville-Hotels-Quality-Inn-Suites.h218540.Hotel-Information) ![Drury Plaza Hotel Mt. Vernon](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b_y.jpg) ### Drury Plaza Hotel Mt. Vernon 10/10 Excellent "Clean environment. Friendly staff. Easy to get to. Pack your own shampoo/body wash. They provide it, which is convenient, but it stinks IMO" [](https://expedia.ca/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Drury Inn & Suites St. Louis Fairview Heights](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/c56c0460_y.jpg) ### Drury Inn & Suites St. Louis Fairview Heights 10/10 Excellent "Breakfast was wonderful. Most comfortable beds we have had in a hotel. Great Place" [](https://expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) ![Drury Inn & Suites St. Louis O'Fallon, IL](https://images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/d2bc121f_y.jpg) ### Drury Inn & Suites St. Louis O'Fallon, IL 10/10 Excellent "Gteat facility. Wonderful staff, clean facility, great rooms, and an amazing evening 'snack'." [](https://expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-OFallon.h1544028.Hotel-Information) ![Red Lion Inn & Suites Pontoon Beach](https://images.trvl-media.com/lodging/1000000/20000/17400/17338/284b6d11_y.jpg) ### Red Lion Inn & Suites Pontoon Beach 10/10 Excellent "Room was clean, staff were really nice & helpful!! We will be back!" [](https://expedia.ca/St-Louis-Hotels-Red-Lion-Inn-Suites-Pontoon-Beach.h17338.Hotel-Information) ![Super 8 by Wyndham O'Fallon](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b_y.jpg) ### Super 8 by Wyndham O'Fallon 10/10 Excellent "Staff were very friendly. It was clean & quiet. I will definitely stop again on my next trip. " [](https://expedia.ca/Collinsville-Hotels-Super-8-By-Wyndham-OFallon.h11071.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Collinsville - St. Louis](https://images.trvl-media.com/lodging/10000000/9650000/9642800/9642754/77e26325_y.jpg) ### La Quinta Inn & Suites by Wyndham Collinsville - St. Louis 10/10 Excellent "Clean quiet,no complaints always stay there when in town" [](https://expedia.ca/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Collinsville-St-Louis.h9642754.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [2 Star Hotels in Nashville ](https://www.expedia.ca/2Star-Nashville-Hotels.s20-0-d180762.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Venedy ](https://www.expedia.ca/4Star-Venedy-Hotels.s40-0-d553248634983275921.Travel-Guide-Filter-Hotels) - [Addieville Hotels ](https://www.expedia.ca/Addieville-Hotels.d3000420807.Travel-Guide-Hotels) - [Albers Hotels ](https://www.expedia.ca/Albers-Hotels.d553248634983546501.Travel-Guide-Hotels) - 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