Title: Hotels by Best Western in Southwest Illinois | Expedia.ca [Southwest Illinois Travel Guide](https://expedia.ca/Southwest-Illinois.dx6058943)[Hotels in Southwest Illinois](https://expedia.ca/Southwest-Illinois-Hotels.d6058943.Travel-Guide-Hotels)[Vacation Rentals in Southwest Illinois](https://expedia.ca/Southwest-Illinois-Vacation-Rentals.d6058943.Travel-Guide-VacationRentals)[Flights to Southwest Illinois](https://expedia.ca/Cheap-Flights-To-Southwest-Illinois.d6058943.Travel-Guide-Flights)[Southwest Illinois Car Rentals](https://expedia.ca/Car-Rentals-In-Southwest-Illinois.d6058943.Car-Rental-Guide)[Southwest Illinois Vacation Packages](https://expedia.ca/Southwest-Illinois.d6058943.Destination-Travel-Guides) ![Southern Illinois featuring a river or creek and landscape views](https://images.trvl-media.com/place/6058943/a3c7ccd1-a184-4026-bf14-8bf0338ee44f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Southernmost Illinois Tourism Bureau # Find Hotels by Best Western in Southwest Illinois - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=6058943&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=6058943&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6058943&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6058943&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouthwest-Illinois-Hotels-Best-Western.0-0-d6058943--bBestWestern.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouthwest-Illinois-Hotels-Best-Western.0-0-d6058943--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Southwest Illinois Hotel Reviews ![Drury Inn & Suites Marion](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/a8315e37_y.jpg) ### Drury Inn & Suites Marion 10/10 Excellent "Clean room, good food" [](https://expedia.ca/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information) ![Drury Plaza Hotel Mt. Vernon](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b_y.jpg) ### Drury Plaza Hotel Mt. Vernon 10/10 Excellent "Short weekend, clean room, very bright atmosphere, super clean, great staff, no issues will stay again. " [](https://expedia.ca/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![The Principal Hotel](https://images.trvl-media.com/lodging/107000000/106860000/106856200/106856168/5d07ff1f_y.jpg) ### The Principal Hotel 10/10 Excellent "Last week I attended a wedding at “The Principal Hotel” in Columbia, Illinois. I would like to start with the owner and the hotel staff. The way they greeted us made us feel truly welcome. The venue was a converted Catholic Abbey and school. All facets of the wedding from the wedding party dinner, the wedding, the social hour, the catered banquet, and the DJ services went off without one glitch. The on-site restaurant was superb and catered delicious food. The hotel was as detailed as you would expect it to be from a long past era. I believe each large room had previously been a classroom. The main thing I noticed was the true quality of the carpentry done by masters that took exceptional pride in their work. Old class pictures, a trophy case, small chair desks, wall lockers, library books, even the old pull out bleacher facings. Quite a nostalgic trip into my memory. I loved every moment of it. I cannot express my appreciation of The Principal Hotel enough. All I can say is wow! Wow! WOW!" [](https://expedia.ca/Columbia-Hotels-The-Principal-Hotel.h106856168.Hotel-Information) ![Comfort Suites Mount Vernon](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b34f836a_y.jpg) ### Comfort Suites Mount Vernon 10/10 Excellent "Very clean, good breakfast included. Night staff was very friendly and good. 😊 " [](https://expedia.ca/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Drury Inn & Suites St. Louis Fairview Heights](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/c56c0460_y.jpg) ### Drury Inn & Suites St. Louis Fairview Heights 10/10 Excellent "I always stay at Drury whenever I can, you can always count on having a great stay! Clean rooms, complimentary cocktails, Hot breakfast, AND complimentary hors d’oeuvres!! " [](https://expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) ![Days Inn by Wyndham Collinsville/St. Louis](https://images.trvl-media.com/lodging/1000000/50000/42100/42033/e64aa27b_y.jpg) ### Days Inn by Wyndham Collinsville/St. Louis 10/10 Excellent "My dog loved it. Great staff !!!" [](https://expedia.ca/Collinsville-Hotels-Days-Inn-By-Wyndham-Collinsville.h42033.Hotel-Information) ![Drury Inn & Suites St. Louis O'Fallon, IL](https://images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/d2bc121f_y.jpg) ### Drury Inn & Suites St. Louis O'Fallon, IL 10/10 Excellent "The Breakfast was nice and saved us money on the trip. Hotel and rooms were very clean and all the workers were very nice. Local was good for anything you would need and close the St. Louis" [](https://expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-OFallon.h1544028.Hotel-Information) ![La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/c5041840_y.jpg) ### La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis 8/10 Good "Clean bed and room. Very nice staff" [](https://expedia.ca/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-OFallon.h201286.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Collinsville - St. Louis](https://images.trvl-media.com/lodging/10000000/9650000/9642800/9642754/77e26325_y.jpg) ### La Quinta Inn & Suites by Wyndham Collinsville - St. Louis 10/10 Excellent "Clean rooms " [](https://expedia.ca/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Collinsville-St-Louis.h9642754.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [2 Star Hotels in Nashville ](https://www.expedia.ca/2Star-Nashville-Hotels.s20-0-d180762.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Venedy ](https://www.expedia.ca/4Star-Venedy-Hotels.s40-0-d553248634983275921.Travel-Guide-Filter-Hotels) - [Addieville Hotels ](https://www.expedia.ca/Addieville-Hotels.d3000420807.Travel-Guide-Hotels) - [Albers Hotels ](https://www.expedia.ca/Albers-Hotels.d553248634983546501.Travel-Guide-Hotels) - 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