Title: Book the Best Southwest LUXURY Hotels - Upscale Hotels in Southwest, MS | Expedia.ca [Southwest Travel Guide](https://expedia.ca/Southwest.dx6058704)[Hotels in Southwest](https://expedia.ca/Southwest-Hotels.d6058704.Travel-Guide-Hotels)[Vacation Rentals in Southwest](https://expedia.ca/Southwest-Vacation-Rentals.d6058704.Travel-Guide-VacationRentals)[Flights to Southwest](https://expedia.ca/Cheap-Flights-To-Southwest.d6058704.Travel-Guide-Flights)[Things to do in Southwest](https://expedia.ca/Things-To-Do-In-Southwest.d6058704.Travel-Guide-Activities)[Southwest Car Rentals](https://expedia.ca/Car-Rentals-In-Southwest.d6058704.Car-Rental-Guide)[Southwest Vacation Packages](https://expedia.ca/Southwest.d6058704.Destination-Travel-Guides) ![Not the most spectacular photo but a very spectacular building and story. This 150-year-old house was never completed. The exterior incredibly magnificent but step inside and the top four floors… Or still in the same condition as when the craftsman left in 1865. Well worth the stop!](https://images.trvl-media.com/place/7671/fef4ceb3-3748-46c9-b2f8-73d43339f6b6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Quentin White # Find luxury hotels in Southwest, MS - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southwest Luxury Hotels Tonight [Dec 2 - Dec 3](https://www.expedia.ca/Hotel-Search?regionId=6058704&startDate=2025-12-02&endDate=2025-12-03&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Dec 3 - Dec 4](https://www.expedia.ca/Hotel-Search?regionId=6058704&startDate=2025-12-03&endDate=2025-12-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6058704&startDate=2025-12-05&endDate=2025-12-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6058704&startDate=2025-12-12&endDate=2025-12-14&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Southwest Luxury Hotels ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/19900/19806/b5566313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed (The Newman Room)](https://images.trvl-media.com/lodging/1000000/20000/19900/19806/e3fdc006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19900/19806/28652090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed (John R. Lynch)](https://images.trvl-media.com/lodging/1000000/20000/19900/19806/1506f9c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Guest House Historic Mansion Natchez 9.2/10 Wonderful (825) "Place is beautiful, clean, quiet, and staff are awesome!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas CA $157 CA $175 total includes taxes & fees Dec 4 - Dec 5 [](https://www.expedia.ca/Natchez-Hotels-The-Guest-House-Historic-Mansion.h19806.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/13000000/12510000/12504700/12504628/b7dce294.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pemberton Suite | Living area](https://images.trvl-media.com/lodging/13000000/12510000/12504700/12504628/acb5378a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/13000000/12510000/12504700/12504628/5bc6ea38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard view](https://images.trvl-media.com/lodging/13000000/12510000/12504700/12504628/734bdf2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Duff Green Mansion Vicksburg 9.4/10 Exceptional (926) "Had a wonderful time. Very nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa CA $201 CA $221 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Vicksburg-Hotels-Duff-Green-Mansion.h12504628.Hotel-Information) ![Free full breakfast](https://images.trvl-media.com/lodging/1000000/20000/13700/13681/a9ebe183.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/13700/13681/w3837h2560x3y3-3774776c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13700/13681/w3837h2563x3y0-01a8f5ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/1000000/20000/13700/13681/w3836h2563x4y0-4f589984.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Airport Inn Pearl 7.8/10 Good (1000) "Clean and quiet room. Efficient and pleasant check in. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $95 CA $107 total includes taxes & fees Dec 31 - Jan 1, 2026 [](https://www.expedia.ca/Jackson-Hotels-Best-Western-Airport-Inn.h13681.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/25900/25813/45ca9f10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25900/25813/63f5caac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25900/25813/a7f87e61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25900/25813/389bc9c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Vicksburg Vicksburg 7.4/10 Good (1002) "It was clean and staff was friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric [](https://www.expedia.ca/Vicksburg-Hotels-Econo-Lodge-Vicksburg.h25813.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15810000/15800200/15800156/ce08d92c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Room, 1 Queen Bed (Misses Steele's Bedroom)](https://images.trvl-media.com/lodging/16000000/15810000/15800200/15800156/3d38dfc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/16000000/15810000/15800200/15800156/cb45ed1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/16000000/15810000/15800200/15800156/e4b67479.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Steele Cottage Vicksburg 8.8/10 Excellent (170) "We had an amazing stay at Steele Cottage. I can't recommend this place highly enough. I will stay here anytime I'm in Vicksburg " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shawn CA $124 CA $133 total includes taxes & fees Dec 3 - Dec 4 [](https://www.expedia.ca/Vicksburg-Hotels-Steele-Cottage.h15800156.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202701/500d628e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202701/a4ee26d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202701/59199198.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202701/0cb4587e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Canton MS Canton 7.2/10 Good (657) "Clean room fast check-in nice breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $130 CA $141 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Canton-MS.h2202701.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/574d9394.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/15c2b6d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/7253ac73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/d6203f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Natchez Grand Hotel & Suites On the River Natchez 8.6/10 Excellent (1369) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $125 CA $173 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Natchez-Hotels-Natchez-Grand-Hotel-Suites-On-The-River.h1788807.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3060000/3050200/3050127/e8740bc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3060000/3050200/3050127/f888e18f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3060000/3050200/3050127/3c612518.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/4000000/3060000/3050200/3050127/7bfda098.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Jackson Downtown Downtown Jackson 7.0/10 Good (1011) "Love staying here" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emily CA $107 CA $119 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Jackson-Hotels-Hilton-Garden-Inn-Jackson-Downtown.h3050127.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8071/ed94bf8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/8100/8071/844b8806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8071/a0e8ebfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Oversized Room;with Sofabed)](https://images.trvl-media.com/lodging/1000000/10000/8100/8071/b17fee2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Vicksburg Vicksburg 8.4/10 Very good (1010) "Clean spacious room and friendly helpful staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $130 CA $143 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Vicksburg-Hotels-Best-Western-Vicksburg.h8071.Hotel-Information) ![1 bedroom, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/490000/484100/484003/1d201c1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/490000/484100/484003/113051ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/490000/484100/484003/e146d3b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/490000/484100/484003/f3620080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Vicksburg Vicksburg 7.4/10 Good (1008) "Great customer service. Wasn’t any shampoo but two things conditioner." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher CA $96 CA $106 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Vicksburg-Hotels-Quality-Inn-Vicksburg.h484003.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-16&endDate=2025-12-17®ionId=6058704&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Limited-time deals: save up to 50% on select hotels [Book now](https://expedia.ca/deals?rfrr=AFFINITY_BF_PROMO_6058704) ## Top Southwest Hotel Reviews ![Natchez Grand Hotel & Suites On the River](https://images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/574d9394_y.jpg) ### Natchez Grand Hotel & Suites On the River 10/10 Excellent "Staff was great, location was excellent. The only issue I had was there was thick dust on the AC vents. " [](https://expedia.ca/Natchez-Hotels-Natchez-Grand-Hotel-Suites-On-The-River.h1788807.Hotel-Information) ![Prado Hotel](https://images.trvl-media.com/lodging/1000000/900000/891200/891169/b960ab9a_y.jpg) ### Prado Hotel 10/10 Excellent "Clean rooms, friendly staff, complimentary drinks, ease of check-in. " [](https://expedia.ca/Jackson-Hotels-Drury-Inn-Suites-Jackson-Ridgeland.h891169.Hotel-Information) ![Baymont by Wyndham Jackson/Ridgeland](https://images.trvl-media.com/lodging/1000000/540000/537200/537157/7b452194_y.jpg) ### Baymont by Wyndham Jackson/Ridgeland 10/10 Excellent "10/10 staff great" [](https://expedia.ca/Jackson-Hotels-Baymont-By-Wyndham-JacksonRidgeland.h537157.Hotel-Information) ![Quality Inn & Suites Pearl - Jackson](https://images.trvl-media.com/lodging/1000000/980000/973600/973518/72981665_y.jpg) ### Quality Inn & Suites Pearl - Jackson 10/10 Excellent "The room was very clean, the breakfast bar was very well stocked and clean." [](https://expedia.ca/Jackson-Hotels-Quality-Inn-Suites-Pearl-Jackson.h973518.Hotel-Information) ![Days Inn by Wyndham Natchez](https://images.trvl-media.com/lodging/1000000/20000/11200/11184/301a51d1_y.jpg) ### Days Inn by Wyndham Natchez 10/10 Excellent "Easy check in, comfy, good breakfast " [](https://expedia.ca/Natchez-Hotels-Days-Inn-By-Wyndham-Natchez.h11184.Hotel-Information) ![Hilton Garden Inn Jackson Downtown](https://images.trvl-media.com/lodging/4000000/3060000/3050200/3050127/e8740bc4_y.jpg) ### Hilton Garden Inn Jackson Downtown 10/10 Excellent "We truly enjoyed our stay!!" 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