Title: Book the Best BUSINESS Hotels in Southwest Coast Florida in 2026 | Expedia.ca

[Southwest Coast Florida Travel Guide](https://expedia.ca/Southwest-Coast-Florida.dx6048100)[Hotels in Southwest Coast Florida](https://expedia.ca/Southwest-Coast-Florida-Hotels.d6048100.Travel-Guide-Hotels)[Vacation Rentals in Southwest Coast Florida](https://expedia.ca/Southwest-Coast-Florida-Vacation-Rentals.d6048100.Travel-Guide-VacationRentals)[Flights to Southwest Coast Florida](https://expedia.ca/Cheap-Flights-To-Southwest-Coast-Florida.d6048100.Travel-Guide-Flights)[Southwest Coast Florida Car Rentals](https://expedia.ca/Car-Rentals-In-Southwest-Coast-Florida.d6048100.Car-Rental-Guide)[Southwest Coast Florida Vacation Packages](https://expedia.ca/Southwest-Coast-Florida.d6048100.Destination-Travel-Guides)

![Fort Myers Beach featuring a sunset, a bridge and a beach](https://images.trvl-media.com/place/7194/a3a41af4-04ff-4ed9-8a12-4ad5a2acfee2.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find Business Hotels in Southwest Coast Florida, FL from CA $106

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## Check availability on Southwest Coast Florida Business Hotels

Tonight

[Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6048100&startDate=2025-12-13&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Tomorrow

[Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=6048100&startDate=2025-12-14&endDate=2025-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Next weekend

[Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6048100&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

In two weeks

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6048100&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

## Our top choices for Southwest Coast Florida business-friendly hotels

![Exterior](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/a69cd385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/9ecc1017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/088bfb58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/fe3aa003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

[](https://www.expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Suites-Ft-Myers-Beach-Sanibel-Gateway.h49152700.Hotel-Information)

Fort Myers Beach

9.4/10

Exceptional

(1000)

"Great rooms, good staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dedan

CA $134

CA $149 total

includes taxes & fees

Dec 16 - Dec 17

[](https://www.expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Suites-Ft-Myers-Beach-Sanibel-Gateway.h49152700.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/120000/117100/117009/8db4d91b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/120000/117100/117009/01ed8c5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/120000/117100/117009/d81d6192.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/120000/117100/117009/bbaa2af7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Ambassador Suites Venice

[](https://www.expedia.ca/Sarasota-Hotels-Best-Western-Plus-Ambassador-Suites-Venice.h117009.Hotel-Information)

Venice

9.0/10

Wonderful

(1005)

"Excellent breakfast, free parking."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

SHPENDI

CA $133

CA $151 total

includes taxes & fees

Dec 23 - Dec 24

[](https://www.expedia.ca/Sarasota-Hotels-Best-Western-Plus-Ambassador-Suites-Venice.h117009.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/aa9b23b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/6b3a0fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/2ab8abc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sanibel Island Beach Resort

[](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information)

Mid Island

9.2/10

Wonderful

(1465)

"Courteous staff, easy parking, close beach"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jenna

CA $271

CA $337 total

includes taxes & fees

Dec 14 - Dec 15

[](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/39000000/38220000/38215400/38215316/e948f2e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Design Studio, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/39000000/38220000/38215400/38215316/23c6a2fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Wine bar](https://images.trvl-media.com/lodging/39000000/38220000/38215400/38215316/746f55c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/39000000/38220000/38215400/38215316/c2a1ef6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Kompose Boutique Hotel

[](https://www.expedia.ca/Sarasota-Hotels-Kompose-Hotel-Sarasota.h38215316.Hotel-Information)

Sarasota

9.2/10

Wonderful

(4766)

"Would happily stay here again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

STYLIANOS

CA $86

CA $114 total

includes taxes & fees

Dec 14 - Dec 15

[](https://www.expedia.ca/Sarasota-Hotels-Kompose-Hotel-Sarasota.h38215316.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/a9620a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/bb6d486e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/7d170878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily to-go breakfast for a fee](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/d254153a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Trianon Bonita Bay

[](https://www.expedia.ca/Naples-Hotels-Trianon-Bonita-Bay.h40858.Hotel-Information)

Bonita Bay

9.2/10

Wonderful

(1711)

"The room was great as well as the amenities!!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Fernando

CA $147

CA $164 total

includes taxes & fees

Dec 14 - Dec 15

[](https://www.expedia.ca/Naples-Hotels-Trianon-Bonita-Bay.h40858.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/16c0566c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/a4826c5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/953f373d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/1fa522a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

[](https://www.expedia.ca/Fort-Myers-Hotels-Days-Inn-Suites-By-Wyndham-Fort-Myers-Near-JetBlue-Park.h798422.Hotel-Information)

Daniels Corridor

8.0/10

Very good

(1494)

"Nice and beautiful place to stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maguenne

CA $95

CA $106 total

includes taxes & fees

Dec 14 - Dec 15

[](https://www.expedia.ca/Fort-Myers-Hotels-Days-Inn-Suites-By-Wyndham-Fort-Myers-Near-JetBlue-Park.h798422.Hotel-Information)

![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2210000/2202400/2202318/a6b8efcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/3000000/2210000/2202400/2202318/7facc2d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2210000/2202400/2202318/80e7390b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/3000000/2210000/2202400/2202318/026440dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites

[](https://www.expedia.ca/Port-Charlotte-Charlotte-Harbor-Hotels-Comfort-Inn-Suites.h2202318.Hotel-Information)

Port Charlotte

8.4/10

Very good

(1005)

"Great stuff at check in, very clean room, nice amenities! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anca

CA $123

CA $138 total

includes taxes & fees

Dec 22 - Dec 23

[](https://www.expedia.ca/Port-Charlotte-Charlotte-Harbor-Hotels-Comfort-Inn-Suites.h2202318.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/160000/159000/158967/2bbde5c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/160000/159000/158967/1d4afbb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/160000/159000/158967/ec833164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/160000/159000/158967/c08f3667.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

[](https://www.expedia.ca/Naples-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Bonita-Springs-Naples-N.h158967.Hotel-Information)

Bonita Shores

9.0/10

Wonderful

(1210)

"Smooth and convenient stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ryan

CA $140

CA $157 total

includes taxes & fees

Dec 17 - Dec 18

[](https://www.expedia.ca/Naples-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Bonita-Springs-Naples-N.h158967.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292808/871369fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292808/19e6461a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 7 AM to midnight, sun loungers](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292808/7a1c9058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292808/9a43a803.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Inn & Suites by Radisson, Port Charlotte, FL

[](https://www.expedia.ca/Port-Charlotte-Charlotte-Harbor-Hotels-Country-Inn-Suites-By-Radisson.h2292808.Hotel-Information)

Port Charlotte

7.8/10

Good

(1151)

"Excellent"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mayte

CA $103

CA $115 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/Port-Charlotte-Charlotte-Harbor-Hotels-Country-Inn-Suites-By-Radisson.h2292808.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/d8bd559a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily cooked-to-order breakfast (USD 15.95 per person)](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/fc5edcf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/24e2211e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/044ddbbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Ft Myers

[](https://www.expedia.ca/Fort-Myers-Hotels-Hilton-Garden-Inn-Ft-Myers.h848740.Hotel-Information)

Villas

8.8/10

Excellent

(1009)

"Great amenities, pool and spa, clean room, beautiful lobby and good on site restaurant "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aleksandar

CA $154

CA $172 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/Fort-Myers-Hotels-Hilton-Garden-Inn-Ft-Myers.h848740.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-27&endDate=2025-12-28&regionId=6048100&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true)

## Top Southwest Coast Florida Hotel Reviews

![Naples Grande Beach Resort](https://images.trvl-media.com/lodging/1000000/20000/15900/15898/65da812e_y.jpg)

### Naples Grande Beach Resort

10/10 Excellent

"It was a large spacious room which we loved."

[](https://expedia.ca/Naples-Hotels-Naples-Grande-Beach-Resort.h15898.Hotel-Information)

![Lani Kai Beachfront Resort](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142_y.jpg)

### Lani Kai Beachfront Resort

10/10 Excellent

"Everything was great. Highly recommend. "

[](https://expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information)

![Sanibel Island Beach Resort](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg)

### Sanibel Island Beach Resort

10/10 Excellent

"We will give everything a excellent ,restaurant ,room, for restaurant, staff, and beach"

[](https://expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Naples Downtown](https://images.trvl-media.com/lodging/1000000/30000/24700/24612/1d33d843_y.jpg)

### La Quinta Inn & Suites by Wyndham Naples Downtown

10/10 Excellent

"Good value"

[](https://expedia.ca/Naples-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Naples-Downtown.h24612.Hotel-Information)

![Hibiscus Suites - Gateway to Siesta Key](https://images.trvl-media.com/lodging/2000000/1220000/1213000/1212924/6ff58e07_y.jpg)

### Hibiscus Suites - Gateway to Siesta Key

10/10 Excellent

"Was wonderful stay and I will back. Large rooms well updated "

[](https://expedia.ca/Sarasota-Hotels-Hibiscus-Suites-Gateway-To-Siesta-Key.h1212924.Hotel-Information)

![Hyatt Place Sarasota/Bradenton Airport](https://images.trvl-media.com/lodging/3000000/2280000/2277500/2277489/6e9ac4ec_y.jpg)

### Hyatt Place Sarasota/Bradenton Airport

10/10 Excellent

"Staff was very kind and welcoming "

[](https://expedia.ca/Sarasota-Hotels-Hyatt-Place-SarasotaBradenton-Airport.h2277489.Hotel-Information)

![DiamondHead Beach Resort](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/814c4388_y.jpg)

### DiamondHead Beach Resort

10/10 Excellent

"The resort was wonderful. The rooms were super clean, the staph were attentive, and the view of the ocean were terrific. The sand art contest was going in; but, even with all the extra people around, the service was top shelf. "

[](https://expedia.ca/Fort-Myers-Hotels-DiamondHead-Beach-Resort.h200632.Hotel-Information)

![Holiday Inn Express Cape Coral-Fort Myers Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c_y.jpg)

### Holiday Inn Express Cape Coral-Fort Myers Area by IHG

10/10 Excellent

"Everything was perfect. Molly was great at check-in"

[](https://expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information)

![Hilton Marco Island Beach Resort and Spa](https://images.trvl-media.com/lodging/1000000/20000/17600/17575/65dd4041_y.jpg)

### Hilton Marco Island Beach Resort and Spa

10/10 Excellent

"Nice "

[](https://expedia.ca/Naples-Hotels-Hilton-Marco-Island-Beach-Resort.h17575.Hotel-Information)

## Frequently asked questions

### How much do business-friendly hotels in Southwest Coast Florida cost?

### What are the best business-friendly hotels in Southwest Coast Florida?

### How many business-friendly hotels are there in Southwest Coast Florida?

### What are the best cheap business-friendly hotels in Southwest Coast Florida?

### Are there any family-friendly hotels in Southwest Coast Florida that are also business friendly?

### Are there any 5-star business-friendly hotels in Southwest Coast Florida?

### Why book your business-friendly hotel in Southwest Coast Florida with Expedia?

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### What is there to do in Southwest Coast Florida near my business-friendly hotel?

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