Title: Book the Best Southern Illinois LUXURY Hotels - Upscale Hotels in Southern Illinois, IL | Expedia.ca [Southern Illinois Travel Guide](https://expedia.ca/Southern-Illinois.dx6233859)[Hotels in Southern Illinois](https://expedia.ca/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels)[Vacation Rentals in Southern Illinois](https://expedia.ca/Southern-Illinois-Vacation-Rentals.d6233859.Travel-Guide-VacationRentals)[Flights to Southern Illinois](https://expedia.ca/Cheap-Flights-To-Southern-Illinois.d6233859.Travel-Guide-Flights)[Southern Illinois Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Illinois.d6233859.Car-Rental-Guide)[Southern Illinois Vacation Packages](https://expedia.ca/Southern-Illinois.d6233859.Destination-Travel-Guides) ![Fort Massac State Park showing a statue or sculpture, a lake or waterhole and a park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/208000/208712-Southern-Illinois.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Southern Illinois, IL ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Illinois Luxury Hotels Tonight [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-09-27&endDate=2025-09-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 28 - Sep 29](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-09-28&endDate=2025-09-29&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-10-03&endDate=2025-10-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southern Illinois Luxury Hotels ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/6781e11c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/fd97bf4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/4ace5211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/4ee0764e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Troy IL/St. Louis Area Troy 8.0/10 Very good (1002) "Friendly and very prompt about getting us to our room!" CA $95 CA $105 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/St-Louis-Hotels-Super-8-By-Wyndham-Troy-ILSt-Louis-Area.h1090603.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/50000/49800/49709/b9296654.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![ATM/banking on site](https://images.trvl-media.com/lodging/1000000/50000/49800/49709/da2b5265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/49800/49709/37dd75af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/49800/49709/04574468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn Effingham North Effingham 7.6/10 Good (1007) "Nice hotel" CA $82 CA $91 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Effingham-Hotels-Rodeway-Inn.h49709.Hotel-Information) ![2 bars/lounges](https://images.trvl-media.com/lodging/16000000/15350000/15340400/15340340/8c0f564b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, soundproofing, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/16000000/15350000/15340400/15340340/1cbc1a6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/16000000/15350000/15340400/15340340/c5bcd847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/16000000/15350000/15340400/15340340/59c79c7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Suite Dreams Hotel Mattoon 7.4/10 Good (516) "Great place to stay" CA $118 CA $132 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Effingham-Hotels-Suite-Dreams-Hotel.h15340340.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598928/7d754b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598928/ada044bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598928/27748d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds, River View | View from room](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598928/45bd23af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harrah's Metropolis Hotel & Casino Metropolis 8.2/10 Very good (1009) "Excellent hotel for the overnight stay " CA $123 CA $159 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Metropolis-Hotels-Harrahs-Metropolis-Hotel-Casino.h1598928.Hotel-Information) ![Room, 1 Queen Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/04e0f544.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/cb6402c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/264bbe49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/9818af49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Mt. Vernon IL Mount Vernon 7.8/10 Good (1008) "Decent hotel. Everything's pretty well kept " CA $90 CA $103 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Mount-Vernon-Hotels-Super-8-By-Wyndham-Mt-Vernon-IL.h861371.Hotel-Information) ![Suite, 1 Bedroom, Non Smoking (1 King Bed and 1 Queen Bed)](https://images.trvl-media.com/lodging/1000000/910000/902400/902318/a1cede69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/910000/902400/902318/53dfd987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/902400/902318/7a86f04b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/910000/902400/902318/cc360cb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Effingham Effingham 6.0/10 (1002) "This was a great place to stay " CA $71 CA $80 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Effingham-Hotels-Days-Inn-By-Wyndham-Effingham.h902318.Hotel-Information) ![Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/440000/439700/439693/8adbc8b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Room amenity](https://images.trvl-media.com/lodging/1000000/440000/439700/439693/101307ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/439700/439693/62f18e1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/440000/439700/439693/0e9cb628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Carbondale Carbondale 7.4/10 Good (1008) "The hotel was very clean & the breakfast was more than enough " CA $91 CA $104 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Carbondale-Hotels-Super-8-By-Wyndham-Carbondale.h439693.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1860000/1850700/1850633/c6bf8414.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1860000/1850700/1850633/154755ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1860000/1850700/1850633/6393c6ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1860000/1850700/1850633/34de46a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Mattoon by IHG Mattoon 8.2/10 Very good (736) "Good location " CA $146 CA $164 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Effingham-Hotels-Holiday-Inn-Express-Suites-Mattoon.h1850633.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/08714d2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/98936ea6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/c64614a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/63665e0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Effingham North Effingham 8.4/10 Very good (957) "Clean nice hotel" CA $120 CA $134 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Effingham-Hotels-Quality-Inn-Effingham.h82513.Hotel-Information) ![Deluxe Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10 AM to 10 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/e59929f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/bad6b55f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/449866d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham O'Fallon O'Fallon 7.4/10 Good (1003) "Comfortable and clean. Its a little dated and the breakfast is a little meager, but totally workable." CA $71 CA $82 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Collinsville-Hotels-Super-8-By-Wyndham-OFallon.h11071.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-11&endDate=2025-10-12®ionId=6233859&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Southern Illinois ### Southern Illinoisand its attractions for luxury travelers Southern Illinois offers an intriguing blend of natural beauty and cultural experiences, making it a unique spot for the discerning traveller. Begin your exploration in the Shawnee National Forest, where you can hike the stunning trails, marvel at the towering rock formations of Giant City State Park, or even try your hand at horseback riding through picturesque landscapes. For a more leisurely pace, indulge in wine tasting at the numerous vineyards along the Shawnee Hills Wine Trail, where you can savour exquisite local wines paired with gourmet dining options. Don't miss the captivating Cache River State Natural Area, home to ancient cypress swamps and rich biodiversity, ideal for birdwatching and serene canoeing adventures. For a touch of history and culture, visit the charming town of Carbondale, where you can enjoy fine dining at upscale restaurants and explore local art galleries. For your luxurious stay, consider the exclusive accommodations in the heart of this region, such as the beautiful Stone Creek Lodge, which offers a rustic yet refined atmosphere complete with modern amenities and attentive service that caters to your every need. Here, you can unwind in style after a day of exploration, enjoying the comfort and convenience that make your stay utterly relaxing. ## Top Southern Illinois Hotel Reviews ![Drury Plaza Hotel Mt. Vernon](//images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b_y.jpg) ### Drury Plaza Hotel Mt. Vernon 10/10 Excellent "Outstandingly clean facility staffed by people who almost felt like family. They took pride and where they worked and made me feel like I was coming home." [](https://expedia.ca/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Comfort Suites Mount Vernon](//images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b34f836a_y.jpg) ### Comfort Suites Mount Vernon 10/10 Excellent "The pool and gym are open 24 hrs, and its pet friendly!" [](https://expedia.ca/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Sleep Inn O'Fallon near I-64](//images.trvl-media.com/lodging/1000000/170000/168400/168383/8c254240_y.jpg) ### Sleep Inn O'Fallon near I-64 10/10 Excellent "Overall experience was very good. There was some trash outside the front of the property. Neither ice machine was working. People staying across from us were noisy." [](https://expedia.ca/Collinsville-Hotels-Sleep-Inn.h168383.Hotel-Information) ![Drury Inn & Suites St. Louis Fairview Heights](//images.trvl-media.com/lodging/1000000/50000/41900/41802/c56c0460_y.jpg) ### Drury Inn & Suites St. Louis Fairview Heights 10/10 Excellent "They need to teach the housekeeping staff to not park their carts in the middle of the hallway. This makes it really hard to navigate the hallway with luggage. " [](https://expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) ![Super 8 by Wyndham Fairview Heights-St. Louis](//images.trvl-media.com/lodging/1000000/440000/439700/439700/12639b39_y.jpg) ### Super 8 by Wyndham Fairview Heights-St. Louis 10/10 Excellent "Love it " [](https://expedia.ca/Collinsville-Hotels-Super-8-By-Wyndham-Fairview-Heights-St-Louis.h439700.Hotel-Information) ![Super 8 by Wyndham O'Fallon](//images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b_y.jpg) ### Super 8 by Wyndham O'Fallon 10/10 Excellent "Amazing " [](https://expedia.ca/Collinsville-Hotels-Super-8-By-Wyndham-OFallon.h11071.Hotel-Information) ![Quality Inn O'Fallon IL - St. Louis](//images.trvl-media.com/lodging/1000000/70000/64700/64675/8890354b_y.jpg) ### Quality Inn O'Fallon IL - St. Louis 10/10 Excellent "I have stayed here several times over the past 2 years and like it. My room is clean and the location vey convenient at a reasonable price. " [](https://expedia.ca/Collinsville-Hotels-Quality-Inn-OFallon-I-64.h64675.Hotel-Information) ![Red Lion Inn & Suites Pontoon Beach](//images.trvl-media.com/lodging/1000000/20000/17400/17338/284b6d11_y.jpg) ### Red Lion Inn & Suites Pontoon Beach 10/10 Excellent "Staff was friendly. Location was close to our activities. " [](https://expedia.ca/St-Louis-Hotels-Red-Lion-Inn-Suites-Pontoon-Beach.h17338.Hotel-Information) ![La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis](//images.trvl-media.com/lodging/1000000/210000/201300/201286/c5041840_y.jpg) ### La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis 10/10 Excellent "Everything was good." [](https://expedia.ca/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-OFallon.h201286.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Ashley Hotels](https://www.expedia.ca/Ashley-Hotels.d553248634983445011.Travel-Guide-Hotels) - [Belle Prairie City Hotels](https://www.expedia.ca/Belle-Prairie-City-Hotels.d553248634983187790.Travel-Guide-Hotels) - [Vacation Homes in Belle Prairie City](https://www.expedia.ca/Belle-Prairie-City-Private-Vacation-Homes.d553248634983187790-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Belle Rive Hotels](https://www.expedia.ca/Belle-Rive-Hotels.d78467.Travel-Guide-Hotels) - [Lodges in Belle Rive](https://www.expedia.ca/Belle-Rive-Lodges.d78467-aaLodges.Travel-Guide-Accommodation) - [B&B in Benton](https://www.expedia.ca/Benton-Bed-And-Breakfast.d6866-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Benton](https://www.expedia.ca/Benton-Guest-Houses.d6866-aaGuestHouses.Travel-Guide-Accommodation) - 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