Title: Book the Best Southern Illinois LUXURY Hotels - Upscale Hotels in Southern Illinois, IL | Expedia.ca [Southern Illinois Travel Guide](https://expedia.ca/Southern-Illinois.dx6233859)[Hotels in Southern Illinois](https://expedia.ca/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels)[Vacation Rentals in Southern Illinois](https://expedia.ca/Southern-Illinois-Vacation-Rentals.d6233859.Travel-Guide-VacationRentals)[Flights to Southern Illinois](https://expedia.ca/Cheap-Flights-To-Southern-Illinois.d6233859.Travel-Guide-Flights)[Southern Illinois Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Illinois.d6233859.Car-Rental-Guide)[Southern Illinois Vacation Packages](https://expedia.ca/Southern-Illinois.d6233859.Destination-Travel-Guides) ![Southern Illinois featuring a sunset, forests and landscape views](https://images.trvl-media.com/place/553248635944113522/0e29d2f8-2d58-457a-908d-4b89b13776d9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Southernmost Illinois Tourism Bureau ![](https://images.trvl-media.com/place/553248635944113522/0e29d2f8-2d58-457a-908d-4b89b13776d9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Illinois Luxury Hotels Tonight [Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2026-02-05&endDate=2026-02-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Feb 6 - Feb 7](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2026-02-06&endDate=2026-02-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2026-02-06&endDate=2026-02-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2026-02-13&endDate=2026-02-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Southern Illinois luxury hotels ![Sauna, hot tub, body treatments, hot stone massages](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/8fcd4708.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/a0fca68c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/84958281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/3a123ac6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Walker's Bluff Casino Resort [](https://www.expedia.ca/Carterville-Hotels-Walkers-Bluff-Casino-Resort.h97064786.Hotel-Information) Carterville 9.4/10 Exceptional (413 reviews) "Our room was clean, and very spacious! the establishment was very nice! We had reservations at Ruthie’s and it was amazing like always " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy CA $218 CA $242 total includes taxes & fees Mar 2 - Mar 3 [](https://www.expedia.ca/Carterville-Hotels-Walkers-Bluff-Casino-Resort.h97064786.Hotel-Information) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/5600/5553/5af8e624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5600/5553/86d47a64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5600/5553/7cac1c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/5600/5553/ec25eb2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Mt. Vernon [](https://www.expedia.ca/Mount-Vernon-Hotels-DoubleTree-By-Hilton-Mt-Vernon.h5553.Hotel-Information) Mount Vernon 8.4/10 Very good (775 reviews) "Wonderful place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wendell CA $174 CA $196 total includes taxes & fees Feb 20 - Feb 21 [](https://www.expedia.ca/Mount-Vernon-Hotels-DoubleTree-By-Hilton-Mt-Vernon.h5553.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27100/27006/579b996f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/30000/27100/27006/5581a60c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/27100/27006/35f1a1de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Courtyard View](https://images.trvl-media.com/lodging/1000000/30000/27100/27006/050895e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Collinsville - St. Louis [](https://www.expedia.ca/Collinsville-Hotels-DoubleTree-By-Hilton-Collinsville-St-Louis.h27006.Hotel-Information) Eastport 8.2/10 Very good (1,000 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patrina CA $175 CA $201 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Collinsville-Hotels-DoubleTree-By-Hilton-Collinsville-St-Louis.h27006.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/124000000/123050000/123048300/123048290/0b27031e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/124000000/123050000/123048300/123048290/47d488ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Suite](https://images.trvl-media.com/lodging/124000000/123050000/123048300/123048290/aef8249a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/124000000/123050000/123048300/123048290/a9cf7169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charleston House Bed & Breakfast Inn [](https://www.expedia.ca/Charleston-Hotels-Charleston-House-Bed-Breakfast-Inn.h123048290.Hotel-Information) Charleston CA $152 CA $169 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Charleston-Hotels-Charleston-House-Bed-Breakfast-Inn.h123048290.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/70b128db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Nightclub](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/4519749c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![6 restaurants, breakfast served](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/d825c5c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/w2880h1936x0y0-34b8c827.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ameristar Casino Resort and Spa [](https://www.expedia.ca/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) St. Charles 8.4/10 Very good (1,000 reviews) "The room was great. I enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wanda CA $245 CA $309 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) ![3 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/1000000/20000/12700/12639/e5dc786b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/12700/12639/19fa7016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/1000000/20000/12700/12639/e242c22e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/20000/12700/12639/0f677423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton St. Louis at the Ballpark [](https://www.expedia.ca/St-Louis-Hotels-Hilton-St-Louis-At-The-Ballpark.h12639.Hotel-Information) Downtown St. Louis 7.6/10 Good (1,076 reviews) "Great location. Nice place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth CA $219 CA $260 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/St-Louis-Hotels-Hilton-St-Louis-At-The-Ballpark.h12639.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/9bee4fd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/34e1f351.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/b33f7b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/af72bf51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Royal Sonesta Chase Park Plaza St. Louis [](https://www.expedia.ca/St-Louis-Hotels-The-Chase-Park-Plaza-Royal-Sonesta-St-Louis.h465749.Hotel-Information) Central West End 9.0/10 Wonderful (1,001 reviews) "Clean room, friendly staff, nice on site amenities " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Russell CA $239 CA $322 total includes taxes & fees Feb 7 - Feb 8 [](https://www.expedia.ca/St-Louis-Hotels-The-Chase-Park-Plaza-Royal-Sonesta-St-Louis.h465749.Hotel-Information) ![5 restaurants, breakfast, dinner served; American cuisine](https://images.trvl-media.com/lodging/102000000/101750000/101749800/101749750/2fa826c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![6 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/102000000/101750000/101749800/101749750/11323991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/102000000/101750000/101749800/101749750/650c7224.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 restaurants, breakfast, dinner served; American cuisine](https://images.trvl-media.com/lodging/102000000/101750000/101749800/101749750/31f323b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Terre Haute Casino Resort [](https://www.expedia.ca/Terre-Haute-Hotels-Terre-Haute-Casino-Resort.h101749750.Hotel-Information) Terre Haute 9.2/10 Wonderful (785 reviews) "Very clean, good location and excellent value for money" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George CA $176 CA $202 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/Terre-Haute-Hotels-Terre-Haute-Casino-Resort.h101749750.Hotel-Information) ![Oven, stovetop, dishwasher, espresso maker](https://images.trvl-media.com/lodging/104000000/103360000/103357800/103357795/becf52a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/104000000/103360000/103357800/103357795/ab0818b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee and/or coffee maker](https://images.trvl-media.com/lodging/104000000/103360000/103357800/103357795/f7d784c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/104000000/103360000/103357800/103357795/ca731d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arbor Rose Boutique Hotel [](https://www.expedia.ca/Arcola-Hotels-Joyful-Life.h103357795.Hotel-Information) Arcola 9.6/10 Exceptional (36 reviews) "Great place! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Connie CA $203 CA $226 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Arcola-Hotels-Joyful-Life.h103357795.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/45000000/44460000/44452500/44452446/bfa9a7c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Elevator](https://images.trvl-media.com/lodging/45000000/44460000/44452500/44452446/46465b3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![36-inch Smart TV with premium channels, TV](https://images.trvl-media.com/lodging/45000000/44460000/44452500/44452446/901ca6ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/45000000/44460000/44452500/44452446/f4a93dba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Respite Bed and Breakfast [](https://www.expedia.ca/Paducah-Hotels-The-Respite-Bed-And-Breakfast.h44452446.Hotel-Information) Paducah 9.8/10 Exceptional (290 reviews) "Nice stay and great breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cynthia [](https://www.expedia.ca/Paducah-Hotels-The-Respite-Bed-And-Breakfast.h44452446.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-19&endDate=2026-02-20®ionId=6233859&adults=2&sort=LUXURY&star=40,50&openPlayBack=true) ## Find out more about Southern Illinois ### Southern Illinoisand its attractions for luxury travelers Southern Illinois offers an intriguing blend of natural beauty and cultural experiences, making it a unique spot for the discerning traveller. Begin your exploration in the Shawnee National Forest, where you can hike the stunning trails, marvel at the towering rock formations of Giant City State Park, or even try your hand at horseback riding through picturesque landscapes. For a more leisurely pace, indulge in wine tasting at the numerous vineyards along the Shawnee Hills Wine Trail, where you can savour exquisite local wines paired with gourmet dining options. Don't miss the captivating Cache River State Natural Area, home to ancient cypress swamps and rich biodiversity, ideal for birdwatching and serene canoeing adventures. For a touch of history and culture, visit the charming town of Carbondale, where you can enjoy fine dining at upscale restaurants and explore local art galleries. For your luxurious stay, consider the exclusive accommodations in the heart of this region, such as the beautiful Stone Creek Lodge, which offers a rustic yet refined atmosphere complete with modern amenities and attentive service that caters to your every need. Here, you can unwind in style after a day of exploration, enjoying the comfort and convenience that make your stay utterly relaxing. ## Top Southern Illinois Hotel Reviews ![Drury Plaza Hotel Mt. Vernon](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b_y.jpg) ### Drury Plaza Hotel Mt. Vernon 10/10 Excellent "This place had free drinks, happy hour, great stay friendly staff great room , dog friendly.Beau" [](https://expedia.ca/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Comfort Suites Mount Vernon](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b34f836a_y.jpg) ### Comfort Suites Mount Vernon 10/10 Excellent "Size and condition of room" [](https://expedia.ca/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Red Lion Inn & Suites Pontoon Beach](https://images.trvl-media.com/lodging/1000000/20000/17400/17338/284b6d11_y.jpg) ### Red Lion Inn & Suites Pontoon Beach 10/10 Excellent "Great breakfast! Staff was friendly. " [](https://expedia.ca/St-Louis-Hotels-Red-Lion-Inn-Suites-Pontoon-Beach.h17338.Hotel-Information) ![Drury Inn & Suites St. Louis Fairview Heights](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/c56c0460_y.jpg) ### Drury Inn & Suites St. Louis Fairview Heights 10/10 Excellent "Clean room, comfortable bed, easy check in, friendly staff. " [](https://expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) ![Super 8 by Wyndham O'Fallon](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b_y.jpg) ### Super 8 by Wyndham O'Fallon 10/10 Excellent "Yes " [](https://expedia.ca/Collinsville-Hotels-Super-8-By-Wyndham-OFallon.h11071.Hotel-Information) ![Sleep Inn O'Fallon near I-64](https://images.trvl-media.com/lodging/1000000/170000/168400/168383/8c254240_y.jpg) ### Sleep Inn O'Fallon near I-64 10/10 Excellent "Clean and quiet. Slept well." [](https://expedia.ca/Collinsville-Hotels-Sleep-Inn.h168383.Hotel-Information) ![La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/c5041840_y.jpg) ### La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis 10/10 Excellent "Everything was really good." [](https://expedia.ca/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-OFallon.h201286.Hotel-Information) ![Quality Inn O'Fallon IL - St. Louis](https://images.trvl-media.com/lodging/1000000/70000/64700/64675/8890354b_y.jpg) ### Quality Inn O'Fallon IL - St. Louis 10/10 Excellent "Great place to stay, very helpful ataff!" [](https://expedia.ca/Collinsville-Hotels-Quality-Inn-OFallon-I-64.h64675.Hotel-Information) ![Super 8 by Wyndham Troy IL/St. Louis Area](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/6781e11c_y.jpg) ### Super 8 by Wyndham Troy IL/St. Louis Area 10/10 Excellent "Fast easy going people " [](https://expedia.ca/St-Louis-Hotels-Super-8-By-Wyndham-Troy-ILSt-Louis-Area.h1090603.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Ashley Hotels ](https://www.expedia.ca/Ashley-Hotels.d553248634983445011.Travel-Guide-Hotels) - [Belle Prairie City Hotels ](https://www.expedia.ca/Belle-Prairie-City-Hotels.d553248634983187790.Travel-Guide-Hotels) - [Vacation Homes in Belle Prairie City ](https://www.expedia.ca/Belle-Prairie-City-Private-Vacation-Homes.d553248634983187790-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Belle Rive Hotels ](https://www.expedia.ca/Belle-Rive-Hotels.d78467.Travel-Guide-Hotels) - 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