Title: Book the Best Southern Illinois LUXURY Hotels - Upscale Hotels in Southern Illinois, IL | Expedia.ca [Southern Illinois Travel Guide](https://expedia.ca/Southern-Illinois.dx6233859)[Hotels in Southern Illinois](https://expedia.ca/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels)[Vacation Rentals in Southern Illinois](https://expedia.ca/Southern-Illinois-Vacation-Rentals.d6233859.Travel-Guide-VacationRentals)[Flights to Southern Illinois](https://expedia.ca/Cheap-Flights-To-Southern-Illinois.d6233859.Travel-Guide-Flights)[Southern Illinois Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Illinois.d6233859.Car-Rental-Guide)[Southern Illinois Vacation Packages](https://expedia.ca/Southern-Illinois.d6233859.Destination-Travel-Guides) ![Fort Massac State Park showing a statue or sculpture, a lake or waterhole and a park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/208000/208712-Southern-Illinois.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Southern Illinois, IL - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Illinois Luxury Hotels Tonight [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-10-31&endDate=2025-11-01&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-11-01&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6233859&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Southern Illinois Luxury Hotels ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/6781e11c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/4ace5211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/fd97bf4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/5a226f6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Troy IL/St. Louis Area Troy 8.0/10 Very good (1002) "Room was comfortable and staff was nice. Lots of quick food options nearby and close to the interstate which was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexandria CA $89 CA $99 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/St-Louis-Hotels-Super-8-By-Wyndham-Troy-ILSt-Louis-Area.h1090603.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/50000/49800/49709/b9296654.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/49800/49709/37dd75af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually furnished, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/49800/49709/edd67707.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![ATM/banking on site](https://images.trvl-media.com/lodging/1000000/50000/49800/49709/da2b5265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn Effingham North Effingham 7.6/10 Good (1004) "Nice hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet CA $83 CA $92 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Effingham-Hotels-Rodeway-Inn.h49709.Hotel-Information) ![Superior Room (Two Full Bed)](https://images.trvl-media.com/lodging/16000000/15350000/15340400/15340340/24e23d36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/16000000/15350000/15340400/15340340/77286326.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/16000000/15350000/15340400/15340340/2212d287.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/16000000/15350000/15340400/15340340/e3a82302.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Suite Dreams Motel By Capital O Mattoon I - 57 Mattoon 7.4/10 Good (528) "The lady at the front desk was so nice to us. But the room was filthy & they also have bed bugs " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cortez CA $98 CA $110 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Effingham-Hotels-Suite-Dreams-Hotel.h15340340.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598928/7d754b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds, River View | View from room](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598928/45bd23af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598928/27748d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598928/ada044bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination Metropolis 8.2/10 Very good (1002) "served our purpose " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher CA $123 CA $159 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Metropolis-Hotels-Harrahs-Metropolis-Hotel-Casino.h1598928.Hotel-Information) ![Room, 1 Queen Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/04e0f544.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/9818af49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/cb6402c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/064919b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Mt. Vernon IL Mount Vernon 7.8/10 Good (1010) "Nice place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) STEPHAN CA $106 CA $121 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Mount-Vernon-Hotels-Super-8-By-Wyndham-Mt-Vernon-IL.h861371.Hotel-Information) ![Suite, 1 Bedroom, Non Smoking (1 King Bed and 1 Queen Bed)](https://images.trvl-media.com/lodging/1000000/910000/902400/902318/a1cede69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/902400/902318/ab1932ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/902400/902318/7a86f04b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/910000/902400/902318/53dfd987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Effingham Effingham 6.0/10 (1006) "This was a great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $71 CA $80 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Effingham-Hotels-Days-Inn-By-Wyndham-Effingham.h902318.Hotel-Information) ![Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/440000/439700/439693/8adbc8b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/439700/439693/62f18e1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/440000/439700/439693/b9f7edd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/440000/439700/439693/0e9cb628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Carbondale Carbondale 7.4/10 Good (1004) "The hotel was very clean & the breakfast was more than enough " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jill CA $84 CA $96 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Carbondale-Hotels-Super-8-By-Wyndham-Carbondale.h439693.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1860000/1850700/1850633/c6bf8414.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds (Wet Bar)](https://images.trvl-media.com/lodging/2000000/1860000/1850700/1850633/f13de7fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1860000/1850700/1850633/34de46a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1860000/1850700/1850633/154755ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Mattoon by IHG Mattoon 8.2/10 Very good (743) "Convenient and friendly. Good complimentary breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathryn CA $136 CA $152 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Effingham-Hotels-Holiday-Inn-Express-Suites-Mattoon.h1850633.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/08714d2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/63665e0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/98936ea6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/c64614a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Effingham North Effingham 8.4/10 Very good (976) "Excellent venue" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raymond CA $113 CA $126 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Effingham-Hotels-Quality-Inn-Effingham.h82513.Hotel-Information) ![Deluxe Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/bad6b55f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/ad5778d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/449866d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham O'Fallon O'Fallon 7.2/10 Good (1004) "The staff were very nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Delbert CA $59 CA $68 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Collinsville-Hotels-Super-8-By-Wyndham-OFallon.h11071.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16®ionId=6233859&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Southern Illinois ### Southern Illinoisand its attractions for luxury travelers Southern Illinois offers an intriguing blend of natural beauty and cultural experiences, making it a unique spot for the discerning traveller. Begin your exploration in the Shawnee National Forest, where you can hike the stunning trails, marvel at the towering rock formations of Giant City State Park, or even try your hand at horseback riding through picturesque landscapes. For a more leisurely pace, indulge in wine tasting at the numerous vineyards along the Shawnee Hills Wine Trail, where you can savour exquisite local wines paired with gourmet dining options. Don't miss the captivating Cache River State Natural Area, home to ancient cypress swamps and rich biodiversity, ideal for birdwatching and serene canoeing adventures. For a touch of history and culture, visit the charming town of Carbondale, where you can enjoy fine dining at upscale restaurants and explore local art galleries. For your luxurious stay, consider the exclusive accommodations in the heart of this region, such as the beautiful Stone Creek Lodge, which offers a rustic yet refined atmosphere complete with modern amenities and attentive service that caters to your every need. Here, you can unwind in style after a day of exploration, enjoying the comfort and convenience that make your stay utterly relaxing. ## Top Southern Illinois Hotel Reviews ![Drury Plaza Hotel Mt. Vernon](//images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b_y.jpg) ### Drury Plaza Hotel Mt. Vernon 10/10 Excellent "Too many carbs" [](https://expedia.ca/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Super 8 by Wyndham O'Fallon](//images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b_y.jpg) ### Super 8 by Wyndham O'Fallon 10/10 Excellent "The only thing I didn’t like was the breakfast " [](https://expedia.ca/Collinsville-Hotels-Super-8-By-Wyndham-OFallon.h11071.Hotel-Information) ![Super 8 by Wyndham Fairview Heights-St. Louis](//images.trvl-media.com/lodging/1000000/440000/439700/439700/12639b39_y.jpg) ### Super 8 by Wyndham Fairview Heights-St. Louis 10/10 Excellent "Handicap parking good. Room was clean but recliner was dirty had alot of crumbs on it but the rest was very clean in toom 110 but my daughters room was terrible so changed rooms and next room was just as dirty and had bugs they could not believe how clean our room was her name was Samantha Barranger they stayed 2 nights" [](https://expedia.ca/Collinsville-Hotels-Super-8-By-Wyndham-Fairview-Heights-St-Louis.h439700.Hotel-Information) ![Comfort Suites Mount Vernon](//images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b34f836a_y.jpg) ### Comfort Suites Mount Vernon 10/10 Excellent "We were able to park right outside the door of our room. Fenced pet area for our dog to get some exercise after a long day of travel. Welcoming front desk person when checking in. No trash around the hotel. Lighting around the hotel made us feel safe when walking the dog. Very clean room. No carpet. Very quiet all night. Close to Starbucks to get a coffee for another day of travel." [](https://expedia.ca/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Red Lion Inn & Suites Pontoon Beach](//images.trvl-media.com/lodging/1000000/20000/17400/17338/284b6d11_y.jpg) ### Red Lion Inn & Suites Pontoon Beach 10/10 Excellent "Very nice and clean place. Very quiet and not a rough crowd. Very nice and respecrful employees. " [](https://expedia.ca/St-Louis-Hotels-Red-Lion-Inn-Suites-Pontoon-Beach.h17338.Hotel-Information) ![Drury Inn & Suites St. Louis Fairview Heights](//images.trvl-media.com/lodging/1000000/50000/41900/41802/c56c0460_y.jpg) ### Drury Inn & Suites St. Louis Fairview Heights 10/10 Excellent "Staff member Romello was Awesome. He went above and beyond for us. His customer service skills are exceptional." [](https://expedia.ca/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) ![Quality Inn O'Fallon IL - St. Louis](//images.trvl-media.com/lodging/1000000/70000/64700/64675/8890354b_y.jpg) ### Quality Inn O'Fallon IL - St. Louis 10/10 Excellent "The room was very clean and the beds comfortable. Add to that that it was nice and quiet. " [](https://expedia.ca/Collinsville-Hotels-Quality-Inn-OFallon-I-64.h64675.Hotel-Information) ![Super 8 by Wyndham Troy IL/St. Louis Area](//images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/6781e11c_y.jpg) ### Super 8 by Wyndham Troy IL/St. Louis Area 10/10 Excellent "Left an important medical item and they immediately offered to mail it overnight. So grateful!" [](https://expedia.ca/St-Louis-Hotels-Super-8-By-Wyndham-Troy-ILSt-Louis-Area.h1090603.Hotel-Information) ![Sleep Inn O'Fallon near I-64](//images.trvl-media.com/lodging/1000000/170000/168400/168383/8c254240_y.jpg) ### Sleep Inn O'Fallon near I-64 10/10 Excellent "I had read the negative comments but hoped for the best during my trip. I was pleasantly surprised! My room was very nice, clean and comfortable. I had no complaints about the cleanliness of the room at all. Even the female staff member at the front desk was very accommodating as I called to ask for early check in before I arrived, I was told the fee amount, but when I arrived she did not charge me for it. The breakfast was tasty with a selection of items to choose from. It was a great experience overall and I would definitely stay here again. I did however notice that the hallway floor could be updated or thoroughly cleaned. Beyond that, it was a decent place to stay." [](https://expedia.ca/Collinsville-Hotels-Sleep-Inn.h168383.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Ashley Hotels](https://www.expedia.ca/Ashley-Hotels.d553248634983445011.Travel-Guide-Hotels) - [Belle Prairie City Hotels](https://www.expedia.ca/Belle-Prairie-City-Hotels.d553248634983187790.Travel-Guide-Hotels) - [Vacation Homes in Belle Prairie City](https://www.expedia.ca/Belle-Prairie-City-Private-Vacation-Homes.d553248634983187790-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Belle Rive Hotels](https://www.expedia.ca/Belle-Rive-Hotels.d78467.Travel-Guide-Hotels) - [Lodges in Belle Rive](https://www.expedia.ca/Belle-Rive-Lodges.d78467-aaLodges.Travel-Guide-Accommodation) - [B&B in Benton](https://www.expedia.ca/Benton-Bed-And-Breakfast.d6866-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Benton](https://www.expedia.ca/Benton-Guest-Houses.d6866-aaGuestHouses.Travel-Guide-Accommodation) - 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