Title: Book the Best Southeastern Indiana LUXURY Hotels - Upscale Hotels in Southeastern Indiana | Expedia.ca [Southeastern Indiana Travel Guide](https://expedia.ca/Southeastern-Indiana.dx6233889)[Hotels in Southeastern Indiana](https://expedia.ca/Southeastern-Indiana-Hotels.d6233889.Travel-Guide-Hotels)[Vacation Rentals in Southeastern Indiana](https://expedia.ca/Southeastern-Indiana-Vacation-Rentals.d6233889.Travel-Guide-VacationRentals)[Flights to Southeastern Indiana](https://expedia.ca/Cheap-Flights-To-Southeastern-Indiana.d6233889.Travel-Guide-Flights)[Southeastern Indiana Car Rentals](https://expedia.ca/Car-Rentals-In-Southeastern-Indiana.d6233889.Car-Rental-Guide)[Southeastern Indiana Vacation Packages](https://expedia.ca/Southeastern-Indiana.d6233889.Destination-Travel-Guides) ![Bathe in the forest...find this on the roof of the outdoor shower house down the hill from the guest house.](https://images.trvl-media.com/place/553248635989202622/88a60920-d501-4b4d-b386-caf78a7f4191.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Serendipity Trip # Find luxury hotels in Southeastern Indiana - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeastern Indiana Luxury Hotels Tonight [Dec 28 - Dec 29](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2025-12-28&endDate=2025-12-29&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Dec 29 - Dec 30](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2025-12-29&endDate=2025-12-30&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2026-01-02&endDate=2026-01-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2026-01-09&endDate=2026-01-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Southeastern Indiana luxury hotels ![Front of property](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/cef338e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/22b7d23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Louisville [](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) Downtown Louisville 9.2/10 Wonderful (1002) "Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tammy CA $190 CA $230 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/220feee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves lunch and dinner](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/97ea6860.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/bff88489.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![15 restaurants, breakfast served](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/95e75b78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### West Baden Springs Hotel [](https://www.expedia.ca/West-Baden-Springs-Hotels-West-Baden-Springs-Hotel.h1745075.Hotel-Information) West Baden Springs 9.6/10 Exceptional (310) "The hotel West Baden is awesome they have 24 hour trolley that runs every 15 minutes and will take you anywhere in the area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.ca/West-Baden-Springs-Hotels-West-Baden-Springs-Hotel.h1745075.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/840e31de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/4fd8456f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/2a2a7fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/3c2671ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Brown Hotel [](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information) Downtown Louisville 9.4/10 Exceptional (1163) "Fantastic place to stay in Louisville." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nathaniel [](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information) ![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/ab0af7cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9c82234b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/594caae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Galt House Hotel Trademark Collection by Wyndham [](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) Downtown Louisville 9.0/10 Wonderful (3902) "Great place to stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rochelle CA $182 CA $214 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Dinner served](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/e02820b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/5bea9d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/4e79a8f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/f30004bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites Louisville Downtown [](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information) Downtown Louisville 9.0/10 Wonderful (1125) "Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shunskis CA $167 CA $197 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/1942d798.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/0b818ec5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/bea3ec0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/c90e9ace.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Louisville Downtown [](https://www.expedia.ca/Louisville-Hotels-Econo-Lodge-Downtown-Louisville.h27037.Hotel-Information) Downtown Louisville 7.2/10 Good (1005) "Nice hotel with a great location near Whiskey Row. This is my 3rd stay at this hotel and will definitely come back again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicholas CA $86 CA $101 total includes taxes & fees Jan 10 - Jan 11, 2026 [](https://www.expedia.ca/Louisville-Hotels-Econo-Lodge-Downtown-Louisville.h27037.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/3d017cc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/aa5a75a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/12e6fe89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/e898c223.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Seelbach Hilton Louisville Downtown [](https://www.expedia.ca/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information) Downtown Louisville 8.6/10 Excellent (1003) "Excellent location and a great lobby bar with a top notch bourbon selection. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) vincent CA $200 CA $235 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/48eca275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/a69d7825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/d2a7092d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/d973f209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Corydon [](https://www.expedia.ca/Corydon-Hotels-Baymont-By-Wyndham-Corydon.h67603.Hotel-Information) Corydon 7.6/10 Good (999) "Always a great place to stay for the price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sidney CA $92 CA $102 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Corydon-Hotels-Baymont-By-Wyndham-Corydon.h67603.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/6e350e03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually furnished, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/b9a48afc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/9ed272c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/de60209a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Sellersburg / Louisville North [](https://www.expedia.ca/Sellersburg-Hotels-Travelodge-By-Wyndham-Sellersburg-Louisville-North.h21199.Hotel-Information) Sellersburg 6.6/10 (701) "Room was nice n clean, however checkout is 1100 am , house cleaning seems to be in a hurry to get u outta there, they knocking on the Door at 930, this has happened several times to me." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Curtis CA $92 CA $104 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/Sellersburg-Hotels-Travelodge-By-Wyndham-Sellersburg-Louisville-North.h21199.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/40000/36400/36308/dca338ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/40000/36400/36308/3b0e9031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor banquet area](https://images.trvl-media.com/lodging/1000000/40000/36400/36308/365887fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/1000000/40000/36400/36308/b367526c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### French Lick Springs Hotel [](https://www.expedia.ca/French-Lick-Hotels-French-Lick-Springs-Hotel.h36308.Hotel-Information) Downtown French Lick 9.2/10 Wonderful (248) "We were there for our 50th wedding anniversary with our family. We had 4 rooms which were nice. There were lots of Christmas activities going on. Our dinner at the West Baden resort was wonderful. Both hotels are very nice, but I would recommend the French Lick Hotel if you have kids along." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynda [](https://www.expedia.ca/French-Lick-Hotels-French-Lick-Springs-Hotel.h36308.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-11&endDate=2026-01-12®ionId=6233889&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Southeastern Indiana Hotel Reviews ![Hampton Inn New Albany Louisville West](https://images.trvl-media.com/lodging/1000000/30000/25400/25301/eb53eba8_y.jpg) ### Hampton Inn New Albany Louisville West 10/10 Excellent "yes, room was ok. staff good. the next mornings was a problem was the shower curtain. it was not tall enough to stop the water from flooding down to the toilet. this room 218 is a wheel chair room. I cleaned up the water as best I could. the shower curtain was not tall enough to touch the small roll over barirer for a wheelchair person. I reported tjis to the front desk. the stay is always good." [](https://expedia.ca/Louisville-Hotels-Hampton-Inn-New-Albany-Louisville-West.h25301.Hotel-Information) ![Best Western Green Tree Inn](https://images.trvl-media.com/lodging/1000000/30000/21100/21059/80ec0958_y.jpg) ### Best Western Green Tree Inn 10/10 Excellent "Yes " [](https://expedia.ca/Louisville-Hotels-Best-Western-Green-Tree-Inn.h21059.Hotel-Information) ![Sheraton Louisville Riverside by Marriott](https://images.trvl-media.com/lodging/1000000/20000/17900/17862/14fa367c_y.jpg) ### Sheraton Louisville Riverside by Marriott 10/10 Excellent "Staff was extremely friendly, helpful, and just exceptional all around. From check in to leaving the building we were greeted with kindness. Tim in club level was so kind and funny! I will definitely be staying here again, instead of the Galt House. 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