Title: Browse the Best Southeast Missouri Resorts  | Expedia.ca

  

[Southeast Missouri Travel Guide](https://expedia.ca/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Vacation Rentals in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Vacation-Rentals.d6058763.Travel-Guide-VacationRentals)[Flights to Southeast Missouri](https://expedia.ca/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.ca/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Missouri.d6058763.Car-Rental-Guide)[Southeast Missouri Vacation Packages](https://expedia.ca/Southeast-Missouri.d6058763.Destination-Travel-Guides)

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# Search Resort Hotels in Southeast Missouri

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## Check prices for these dates

Next weekend

[Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-10-24&endDate=2025-10-26&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-10-31&endDate=2025-11-02&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In one month

[Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-11-14&endDate=2025-11-16&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-12-12&endDate=2025-12-14&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Browse Select Southeast Missouri Resorts

We don't have any properties that match your exact search

[See all properties in Southeast Missouri](https://expedia.ca/Hotel-Search?startDate=2025-10-31&endDate=2025-11-01&regionId=6058763&adults=2)

## Recommended hotels in Southeast Missouri

![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds, Accessible, Refrigerator & Microwave (Tub)](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/0941dc05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/ea01e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Sikeston, MO

Sikeston

9.4/10

Exceptional

(1009)

"Very nice and quiet "

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lana

CA $126

CA $145 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

9.6/10

Exceptional

(1019)

"Great place"

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eric

CA $126

CA $143 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/4071c448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/db5aadc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/136440e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children's play area - outdoor](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/104061b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Echo Bluff State Park

Eminence

9.4/10

Exceptional

(209)

"Beautiful location…excellent service and facilities / grounds were clean and well kept."

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

William

CA $190

CA $201 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Rolla-Hotels-Echo-Bluff-State-Park.h15487684.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/060976ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/8003191a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/13275a81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Farmstead Hotel

Caruthersville

8.8/10

Excellent

(428)

"Very nice place to stay at."

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Edina

CA $117

CA $134 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/76c46720.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/d71a605c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/bf46ac12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/cc7b340b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

9.4/10

Exceptional

(823)

"Very friendly staff and clean rooms. My go to hotel!"

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Barbara

CA $143

CA $162 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/Poplar-Bluff-Hotels-Fairfield-Inn-Suites-By-Marriott-Poplar-Bluff.h28807257.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/1d457549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/668f3d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds | Room amenity](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/d42a6e3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Perryville by IHG

Perryville

9.4/10

Exceptional

(519)

"Rooms were clean and everyone was really nice. Only thing I would say is that for the breakfast, the bacon wasn't quite all the way done other than that, a good experience."

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

TEVIS

CA $145

CA $166 total

includes taxes & fees

Oct 20 - Oct 21

[](https://www.expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau Near the Medical Center

Cape Girardeau

9.0/10

Wonderful

(1009)

"Staff was very friendly and helpful would stay again "

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Keith

CA $98

CA $111 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

8.8/10

Excellent

(635)

"We had a restful stay very safe & clean! Friendly staff:)"

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rachel

CA $118

CA $128 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/2dc5e17d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio, 1 King Bed, Non Smoking, Kitchenette](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/25677988.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/e921a7b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/5904f90a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Poplar Bluff

Poplar Bluff

9.4/10

Exceptional

(772)

"Clean room and friendly staff."

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Walter

CA $131

CA $147 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Poplar-Bluff-Hotels-Hampton-Inn-Poplar-Bluff-Mo.h9827793.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/20bc712d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/18325925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

9.6/10

Exceptional

(455)

"The Staff was friendly The restaurant was good"

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sirron

CA $176

CA $199 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Jackson MO

Jackson

9.6/10

Exceptional

(1014)

"Great service! Definitely will stay there again!"

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

CA $126

CA $134 total

includes taxes & fees

Oct 21 - Oct 22

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/13000000/12590000/12582100/12582009/57db158c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Double Room, 2 Queen Beds, Kitchenette | Bathroom](https://images.trvl-media.com/lodging/13000000/12590000/12582100/12582009/99d2e456.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/13000000/12590000/12582100/12582009/8bbae4c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Suite, 1 Queen Bed with Sofa bed, Kitchen | In-room dining](https://images.trvl-media.com/lodging/13000000/12590000/12582100/12582009/a091ce3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Shepherd Mountain Inn

Ironton

9.4/10

Exceptional

(302)

" Nice room, nice bed, convenient location"

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Burton

CA $152

CA $166 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/Farmington-Hotels-Shepherd-Mountain-Inn.h12582009.Hotel-Information)

![Children's play area - outdoor](https://images.trvl-media.com/lodging/43000000/42100000/42093500/42093410/e8909449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/43000000/42100000/42093500/42093410/5013cbb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Single Room](https://images.trvl-media.com/lodging/43000000/42100000/42093500/42093410/868bcfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/43000000/42100000/42093500/42093410/603f552a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Honeysuckle Inn - Mountain View

Mountain View

8.6/10

Excellent

(318)

"Staff was very friendly."

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joyce

CA $134

CA $145 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/Mountain-View-Hotels-Honeysuckle-Inn-Mountain-View.h42093410.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Sikeston

Sikeston

8.8/10

Excellent

(409)

"Nice property and friendly staff."

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nancy

CA $149

CA $168 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/e91b57a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/874a4e6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/4ea0b11e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/0a692e3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Poplar Bluff by IHG

Poplar Bluff

8.8/10

Excellent

(680)

"Staff was friendly and accommodating. Room was quiet and clean."

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lynda

CA $128

CA $145 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Poplar-Bluff-Hotels-Holiday-Inn-Poplar-Bluff.h1222183.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095128/2dd0e783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095128/2993d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095128/7df3af01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1100000/1095200/1095128/c9851c7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Farmington by IHG

Farmington

8.6/10

Excellent

(409)

"Great hotel"

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carole

CA $117

CA $357 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Farmington-Hotels-Holiday-Inn-Express-Suites-Farmington.h1095128.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/032aa313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/284f2de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/a085469e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau West

Cape Girardeau

9.0/10

Wonderful

(1009)

"Close to the interstate so easy to get to when traveling. Nice property - plus that Outback Steakhouse is right next door for dining. We have stayed here numerous times over the years and always pleased. "

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janice

CA $98

CA $111 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/b034b164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Queen Beds, Accessible, Refrigerator & Microwave (Sofabed, 2 Rooms, Tub)](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/83931306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/a3a28e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/239bd50a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Poplar Bluff

Poplar Bluff

9.2/10

Wonderful

(924)

"Dining options were excellent "

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

rob

CA $132

CA $149 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/Poplar-Bluff-Hotels-Drury-Inn-Suites-Poplar-Bluff.h41515.Hotel-Information)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/13000000/12490000/12489600/12489555/fd23ac64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/13000000/12490000/12489600/12489555/a26b8409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/13000000/12490000/12489600/12489555/2af66ba5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/13000000/12490000/12489600/12489555/15fecbba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fort Davidson Hotel

Ironton

9.2/10

Wonderful

(169)

"Clean, comfortable, very friendly staff. Pool area was really nice. Love the location right next to the Fort Davidson historic site! "

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andrew

CA $167

CA $183 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Farmington-Hotels-Fort-Davidson-Hotel.h12489555.Hotel-Information)

![Hallway](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/8e494fe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/3727e01c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/2dc19e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

8.4/10

Very good

(695)

"Stayed one night. Good rate for the Hotel "

![](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paul

CA $76

CA $87 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Southeast Missouri Hotel Reviews

![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg)

### Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Clean. Happy hour at 530, decent breakfast options "

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg)

### Tru By Hilton Cape Girardeau

10/10 Excellent

"Nice staff at the front desk, large comfortable room, very nice hotel!"

[](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information)

![Candlewood Suites Cape Girardeau by IHG](//images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg)

### Candlewood Suites Cape Girardeau by IHG

10/10 Excellent

"Clean room and bathroom, the beds and pillows were comfortable, the bathroom and the room were both really spacious which my toddler loved after being in her car seat she had plenty of room to run freely. The location was safe as well and convenient having a Rhodes close by open late to get snacks and chargers. I was pleased with my stay I felt safe and comfortable."

[](https://expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information)

![Motel 6 Poplar Bluff, MO](//images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg)

### Motel 6 Poplar Bluff, MO

10/10 Excellent

"The Light was on when I needed it the most. "

[](https://expedia.ca/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Festus - St. Louis South](//images.trvl-media.com/lodging/1000000/50000/42200/42120/1887aa70_y.jpg)

### La Quinta Inn & Suites by Wyndham Festus - St. Louis South

10/10 Excellent

" Clean rooms,breakfast "

[](https://expedia.ca/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information)

![Quality Inn](//images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg)

### Quality Inn

10/10 Excellent

"It was so welcoming and peaceful"

[](https://expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information)

![Fairfield Inn & Suites by Marriott Poplar Bluff](//images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/76c46720_y.jpg)

### Fairfield Inn & Suites by Marriott Poplar Bluff

10/10 Excellent

"I had an issue with my door not opening and had to wait a bit for maintenance to come let me in. Everyone was kind and very helpful. The lobby was comfy to relax in while I waited"

[](https://expedia.ca/Poplar-Bluff-Hotels-Fairfield-Inn-Suites-By-Marriott-Poplar-Bluff.h28807257.Hotel-Information)

![The Farmstead Hotel](//images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631_y.jpg)

### The Farmstead Hotel

10/10 Excellent

"Excellent hotel. Very clean."

[](https://expedia.ca/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information)

![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg)

### Pear Tree Inn Cape Girardeau Near the Medical Center

10/10 Excellent

"Room was a bit on the small side, but comfortable."

[](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

## Find out more about Southeast Missouri

## Southeast Missouri Resorts information

| Number of reviews | |
| --- | --- |
| Accommodation | Resorts |
| Lowest Price | |
| Highest Price | |

## Explore a world of travel with Expedia

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-   [Book Resorts in Southeast Missouri on Expedia.com](https://www.expedia.com/Southeast-Missouri-Resorts.d6058763-aaResorts.Travel-Guide-Accommodation)