Title: Southeast Missouri Vacation Home Rentals from CA $138: Search Top Private Vacation Homes for Rent | Expedia.ca

[Southeast Missouri Travel Guide](https://expedia.ca/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Vacation Rentals in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Vacation-Rentals.d6058763.Travel-Guide-VacationRentals)[Flights to Southeast Missouri](https://expedia.ca/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.ca/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Missouri.d6058763.Car-Rental-Guide)[Southeast Missouri Vacation Packages](https://expedia.ca/Southeast-Missouri.d6058763.Destination-Travel-Guides)

![Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg:

Moark Regional Railroad Museum
HOURS: Saturdays 1 p.m. - 4 p.m.

It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history.

This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! 

#MTTS2014 #minitakesthestates #go11
#train](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Bill Dillard

![](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 1 - May 3](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[May 29 - May 31](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Southeast Missouri vacation homes

![Terrace/patio](https://images.trvl-media.com/lodging/84000000/83520000/83516600/83516509/8557dc4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House | Living area](https://images.trvl-media.com/lodging/84000000/83520000/83516600/83516509/cbaecd07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House | Living area](https://images.trvl-media.com/lodging/84000000/83520000/83516600/83516509/972e20f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House](https://images.trvl-media.com/lodging/84000000/83520000/83516600/83516509/e3c698b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tiny Houses of French Village

[](https://www.expedia.ca/French-Village-Hotels-Tiny-Houses-Of-French-Village.h83516509.Hotel-Information)

French Village

10/10

Exceptional

(3 reviews)

"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Norma

[](https://www.expedia.ca/French-Village-Hotels-Tiny-Houses-Of-French-Village.h83516509.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/f432dafb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/0e13dd89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/564d6e43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/a340bc3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Serenity South -- Gardens, River-Views, and Refreshing Space

[](https://www.expedia.ca/Sikeston-Hotels-Serenity-Gardens.h38940154.Hotel-Information)

Cape Girardeau

10/10

Exceptional

(150 reviews)

"Such a great place and location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tracy H.

CA $204

CA $332 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Sikeston-Hotels-Serenity-Gardens.h38940154.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/469a5901.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/d33a9d5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/211494f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/6a739ba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Colorful-Oasis-5mins-To-DownTown-Lush-Yard-W-Summer-PoolVENUE-Now-Open.h71745619.Hotel-Information)

Cape Girardeau

8.8/10

Excellent

(38 reviews)

"Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Emily D.

CA $184

CA $296 total

includes taxes & fees

Feb 5 - Feb 6

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Colorful-Oasis-5mins-To-DownTown-Lush-Yard-W-Summer-PoolVENUE-Now-Open.h71745619.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/113000000/112630000/112624300/112624271/599e7a95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, towels, soap, toilet paper](https://images.trvl-media.com/lodging/113000000/112630000/112624300/112624271/35b4ae99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/113000000/112630000/112624300/112624271/403251a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/113000000/112630000/112624300/112624271/02b08ccf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy upstairs unit in Cape Girardeau

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Cozy-Upstairs-Unit-In-Cape-Girardeau.h112624271.Hotel-Information)

Cape Girardeau

CA $147

CA $174 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Cozy-Upstairs-Unit-In-Cape-Girardeau.h112624271.Hotel-Information)

![Iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/125000000/124500000/124492400/124492322/6c978d1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/125000000/124500000/124492400/124492322/1fd2d237.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace](https://images.trvl-media.com/lodging/125000000/124500000/124492400/124492322/af2b93d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace](https://images.trvl-media.com/lodging/125000000/124500000/124492400/124492322/e701283d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Melody King Suite. Experience peaceful relaxation in this Micro Boutique Hotel

[](https://www.expedia.ca/Alton-Hotels-Melody-King-Suite-Experience-Peaceful-Relaxation-In-This-Micro-Boutique-Hotel.h124492322.Hotel-Information)

Alton

10/10

Exceptional

(1 review)

"Thoroughly enjoyed our stay! Room was clean, welcoming and relaxing. Hosts were pleasant, accommodating and kind. Would highly recommend. We will definitely be back! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paula W.

CA $75

CA $102 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Alton-Hotels-Melody-King-Suite-Experience-Peaceful-Relaxation-In-This-Micro-Boutique-Hotel.h124492322.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/a08b65d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/w830h683x97y0-bd7b87e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/w907h683x60y0-f986d826.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/89000000/89000000/88996300/88996203/w507h683x259y0-84bc4b01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### "Little Brick House on Main (1865)”

[](https://www.expedia.ca/Ste-Genevieve-Hotels-Little-Brick-House.h88996203.Hotel-Information)

Ste. Genevieve

10/10

Exceptional

(67 reviews)

"Great place to stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lettitia B.

CA $162

CA $216 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Ste-Genevieve-Hotels-Little-Brick-House.h88996203.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/109000000/108970000/108967900/108967867/c530a526.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108970000/108967900/108967867/d21e3f12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/109000000/108970000/108967900/108967867/0846a92b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/109000000/108970000/108967900/108967867/70c9d97e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 2-bedroom house with AC, WiFi in serene Van Buren

[](https://www.expedia.ca/Van-Buren-Hotels-Charming-2-Bedroom-House-With-AC.h108967867.Hotel-Information)

Van Buren

9.0/10

Wonderful

(15 reviews)

"It was beautiful and homey. We really enjoyed our stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jessica

CA $95

CA $229 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Van-Buren-Hotels-Charming-2-Bedroom-House-With-AC.h108967867.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/112000000/111430000/111424900/111424805/8466de35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/112000000/111430000/111424900/111424805/b6a3f5d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/112000000/111430000/111424900/111424805/b956cbd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111430000/111424900/111424805/7627f938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy 1-bedroom house with AC and WiFi in charming Farmington

[](https://www.expedia.ca/Farmington-Hotels-Cozy-1-Bedroom-House-With-AC-And-WiFi-In-Charming-Farmington.h111424805.Hotel-Information)

Farmington

10/10

Exceptional

(9 reviews)

"Beautiful and perfect for travelers!!!!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elizabeth

CA $116

CA $265 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Farmington-Hotels-Cozy-1-Bedroom-House-With-AC-And-WiFi-In-Charming-Farmington.h111424805.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/143b0eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/927199d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/9ff1a808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/3867ac72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Little Blue Cottage on Spanish

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information)

Cape Girardeau

8.4/10

Very good

(49 reviews)

"Cozy and perfect for a couple. Great communication with the host"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Beth G.

CA $110

CA $138 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070749/ebd33eb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070749/9b052590.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070749/36c29eb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070749/15338087.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Doc's Cottage - A-Frame in Piggott, AR

[](https://www.expedia.ca/Piggott-Hotels-Docs-Cottage-A-Frame-In-Piggott.h104070749.Hotel-Information)

Piggott

10/10

Exceptional

(11 reviews)

"Very clean and well stocked. Host was excellent to communicate with. We would definitely stay again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ken R.

CA $157

CA $311 total

includes taxes & fees

Feb 4 - Feb 5

[](https://www.expedia.ca/Piggott-Hotels-Docs-Cottage-A-Frame-In-Piggott.h104070749.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/19000000/18790000/18787500/18787495/b169a39d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/19000000/18790000/18787500/18787495/7282fe58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/19000000/18790000/18787500/18787495/6bf61133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18790000/18787500/18787495/6b0c4075.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Get Away Acres 1/2 mile off highway 60 extra sanitized

[](https://www.expedia.ca/Ellsinore-Hotels-Get-Away-Acres-12-Mile-Off-Highway-60-Extra-Sanitized.h18787495.Hotel-Information)

Ellsinore

10/10

Exceptional

(95 reviews)

"We really enjoyed our stay! Host was very friendly and quick to respond to questions! We will definitely stay again!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveller

CA $143

CA $178 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Ellsinore-Hotels-Get-Away-Acres-12-Mile-Off-Highway-60-Extra-Sanitized.h18787495.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/107000000/106850000/106848100/106848020/5458231c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, travel crib, WiFi](https://images.trvl-media.com/lodging/107000000/106850000/106848100/106848020/be9ee859.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/107000000/106850000/106848100/106848020/dc4e06f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace](https://images.trvl-media.com/lodging/107000000/106850000/106848100/106848020/555e828a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Clifford's Country Cottage

[](https://www.expedia.ca/Bonne-Terre-Hotels-Cliffords-Country-Cottage.h106848020.Hotel-Information)

Bonne Terre

10/10

Exceptional

(24 reviews)

"Wife just loved the place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stanley H.

CA $170

CA $207 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Bonne-Terre-Hotels-Cliffords-Country-Cottage.h106848020.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/107000000/106410000/106408100/106408017/d086ec00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/107000000/106410000/106408100/106408017/eeaadf3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/107000000/106410000/106408100/106408017/8e6dee64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/107000000/106410000/106408100/106408017/be129fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### "The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC

[](https://www.expedia.ca/Farmington-Hotels-The-Hideaway-2-Charming-2-Bedroom-House-In-Delightful-Farmington-With-WiFi.h106408017.Hotel-Information)

Farmington

10/10

Exceptional

(8 reviews)

"It is a very nice place and very comfortable has everything you could possibly need for homeaway from home."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Scott

CA $165

CA $317 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Farmington-Hotels-The-Hideaway-2-Charming-2-Bedroom-House-In-Delightful-Farmington-With-WiFi.h106408017.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/0cb5c163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h571x0y55-c44ee136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h570x0y57-9a9602a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h568x0y58-4fff3406.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Your home away from home in downtown, historic Farmington!

[](https://www.expedia.ca/Farmington-Hotels-Your-Home-Away-From-Home-In-Downtown.h100465272.Hotel-Information)

Farmington

10/10

Exceptional

(39 reviews)

"The kitchen was fully equipped and clean. Great place to stay when visiting Farmington!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Linda B.

CA $176

CA $316 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Farmington-Hotels-Your-Home-Away-From-Home-In-Downtown.h100465272.Hotel-Information)

![Smart TV, DVD player](https://images.trvl-media.com/lodging/67000000/66610000/66602200/66602167/13afc175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/67000000/66610000/66602200/66602167/1f771dbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/67000000/66610000/66602200/66602167/d26fc52a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/67000000/66610000/66602200/66602167/1f2f433c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Serene home off 55 Queen Bed Smart TVs Wi-Fi

[](https://www.expedia.ca/Pevely-Hotels-Cozy-Serene-Home-Off-55-Queen-Bed-Smart-TVs-Wifi-Secluded-Nice-View-With-Coffee.h66602167.Hotel-Information)

Pevely

9.8/10

Exceptional

(7 reviews)

"Stay was nice quite and good location for us"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

James S.

CA $327

CA $370 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Pevely-Hotels-Cozy-Serene-Home-Off-55-Queen-Bed-Smart-TVs-Wifi-Secluded-Nice-View-With-Coffee.h66602167.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100840000/100830500/100830468/a5b7d625.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/101000000/100840000/100830500/100830468/89a7af7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/101000000/100840000/100830500/100830468/a80c5b09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, DVD player](https://images.trvl-media.com/lodging/101000000/100840000/100830500/100830468/61bc5568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Three bedroom home in Central Farmington

[](https://www.expedia.ca/Farmington-Hotels-Cozy-Three-Bedroom-Home-In-Central-Farmington.h100830468.Hotel-Information)

Farmington

9.6/10

Exceptional

(29 reviews)

"House was adorable and comfortable. Location close to everything. Drive to The Landing was not bad at all. Host was friendly and available. I would stay again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jody C.

CA $147

CA $336 total

includes taxes & fees

Feb 5 - Feb 6

[](https://www.expedia.ca/Farmington-Hotels-Cozy-Three-Bedroom-Home-In-Central-Farmington.h100830468.Hotel-Information)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/94000000/93460000/93451700/93451673/3ea511d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/94000000/93460000/93451700/93451673/ed7c9b41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/94000000/93460000/93451700/93451673/w904h683x60y0-c0f9bc17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/94000000/93460000/93451700/93451673/w1024h570x0y56-33f70a5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AV Bungalows #9B

[](https://www.expedia.ca/Arcadia-Hotels-AV-Bungalows-9B.h93451673.Hotel-Information)

Arcadia

10/10

Exceptional

(2 reviews)

"My husband and I really enjoyed our stay! The Bungalow was perfect for us and will definitely be staying again when we come back to Arcadia!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Theresa R.

CA $184

CA $227 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Arcadia-Hotels-AV-Bungalows-9B.h93451673.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/d1f3492c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/cf2136e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/877e8abc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/07fcf4cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### "The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

[](https://www.expedia.ca/Farmington-Hotels-The-Hideaway-1-Charming-2-Bedroom-House-With-WiFi.h106406059.Hotel-Information)

Farmington

10/10

Exceptional

(13 reviews)

"The home was very clean and well cared for. It was fully stocked with all the necessities. The bed was comfortable. I would definitely stay here again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Billie N.

CA $165

CA $317 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Farmington-Hotels-The-Hideaway-1-Charming-2-Bedroom-House-With-WiFi.h106406059.Hotel-Information)

![Outdoor spa tub](https://images.trvl-media.com/lodging/124000000/123750000/123743600/123743557/5b24ebbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/124000000/123750000/123743600/123743557/a359d1c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/124000000/123750000/123743600/123743557/4df54871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/124000000/123750000/123743600/123743557/3bafe12d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Retreat Air - King Bed, Hot Tub & No cleaning fee

[](https://www.expedia.ca/Perryville-Hotels-Retreat-Air-King-Bed.h123743557.Hotel-Information)

Perryville

CA $184

CA $211 total

includes taxes & fees

Feb 6 - Feb 7

[](https://www.expedia.ca/Perryville-Hotels-Retreat-Air-King-Bed.h123743557.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/68000000/67450000/67442300/67442249/3ba4052b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/68000000/67450000/67442300/67442249/48aeec9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/68000000/67450000/67442300/67442249/bbb5fb00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, offices](https://images.trvl-media.com/lodging/68000000/67450000/67442300/67442249/0b5d2236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### \*State Parks\*Bungalow\*CoffeeBar\*Pet Friendly\*Porch

[](https://www.expedia.ca/Ironton-Hotels-Pet-Friendly-Downtown-Ironton-Minutes-Away-Elephant-Rocks.h67442249.Hotel-Information)

Ironton

10/10

Exceptional

(34 reviews)

"enjoyed our stay, nice location to downtown and coffee. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aaron L.

CA $157

CA $326 total

includes taxes & fees

Feb 10 - Feb 11

[](https://www.expedia.ca/Ironton-Hotels-Pet-Friendly-Downtown-Ironton-Minutes-Away-Elephant-Rocks.h67442249.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-16&endDate=2026-02-17&regionId=6058763&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Cottages

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Cabins

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Aparthotels

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Apartments

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Private vacation homes

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Condos

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Villas

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## Top Southeast Missouri Hotel Reviews

![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg)

### Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Clean room and shower, ruffled hotel toilet paper, dinner buffet, breakfast buffet, hot tub and pool. And pets are welcome. Great service and great value. "

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Festus - St. Louis South](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/1887aa70_y.jpg)

### La Quinta Inn & Suites by Wyndham Festus - St. Louis South

10/10 Excellent

"Great staff, room was clean and comfortable. Clean and fully stocked breakfast."

[](https://expedia.ca/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information)

![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg)

### Drury Inn & Suites Cape Girardeau

10/10 Excellent

"The room was lage and clean. We really enjoyed the free food and drinks provided."

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Yes everything was great"

[](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

![Motel 6 Poplar Bluff, MO](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg)

### Motel 6 Poplar Bluff, MO

10/10 Excellent

"The stay this time was just wonderful. The staff was more than helpful when we needed extra things and especially when we got stuck for two extra days from the snow. Normally we just get a regular room but this time decided to do a kitchenette. Best decision ever. Made the hallway smell like bacon but no complaints. Thank you for a wonderful staff. I wish I could remember names so I could give praise to the lady who went up and down the hallway getting stuff for us. She told us it was her job but she gave extra attention to detail. Thank you whoever you are. Wish we could’ve tip more!"

[](https://expedia.ca/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information)

![Baymont Inn and Suites by Wyndham Farmington, MO](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_y.jpg)

### Baymont Inn and Suites by Wyndham Farmington, MO

10/10 Excellent

"Clean room and nice staff"

[](https://expedia.ca/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information)

![The Farmstead Hotel](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631_y.jpg)

### The Farmstead Hotel

10/10 Excellent

"Yes"

[](https://expedia.ca/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information)

![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg)

### Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Comfortable beds and pillows Good breakfast "

[](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg)

### Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"This place feels like customer service from 1950\. The service was outstanding "

[](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

## Find out more about Southeast Missouri

## Southeast Missouri Vacation Homes information

| Number of reviews | 580                |
| ----------------- | ------------------ |
| Accommodation     | 190 Vacation Homes |
| Lowest Price      | CA $138            |
| Highest Price     | CA $370            |

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- [K Bridge Recreation Area ](https://www.expedia.ca/K-Bridge-Recreation-Area-Annapolis.d6282501.Vacation-Attraction)
- [Wappapello Vacations ](https://www.expedia.ca/Wappapello.d183505.Destination-Travel-Guides)

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- [Book Vacation Homes in Southeast Missouri on Expedia.com ](https://www.expedia.com/Southeast-Missouri-Private-Vacation-Homes.d6058763-aaPrivateVacationHomes.Travel-Guide-Accommodation)