Title: Book the Best SHOPPING Hotels in Southeast Missouri in 2025 | Expedia.ca [Southeast Missouri Travel Guide](https://expedia.ca/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Vacation Rentals in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Vacation-Rentals.d6058763.Travel-Guide-VacationRentals)[Flights to Southeast Missouri](https://expedia.ca/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.ca/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Missouri.d6058763.Car-Rental-Guide)[Southeast Missouri Vacation Packages](https://expedia.ca/Southeast-Missouri.d6058763.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/9/6538ce9b088c58039b33a5fe701e7a1f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Shopping Hotels in Southeast Missouri, MO ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Missouri Shopping Hotels Tonight [Oct 21 - Oct 22](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-10-21&endDate=2025-10-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 22 - Oct 23](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-10-22&endDate=2025-10-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southeast Missouri Shopping Hotels ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/ed042ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/8874e729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston Sikeston 8.4/10 Very good (1011) "Very convenient and great breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Duwaine CA $118 CA $134 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/708e4b63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/fe7ea7ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's play area - outdoor](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/a1c79fe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/3b9c0313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Current River Inn Van Buren 8.2/10 Very good (162) "The mattresses were fabulous. Clean rooms and friendly staff. We will stay here again. The antique store and restaurants are walking distance. Nice family friendly establishment!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thad CA $122 CA $133 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Van-Buren-Hotels-Current-River-Inn.h47039515.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070754/dc9898b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070754/31e53afa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070754/4b615244.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070754/2c7671ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Morning Glory - Country Cottage Piggott 10/10 Exceptional (2) "Great stay. Home was just as advertised. Great communication with owner. Will visit again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott C. CA $180 CA $337 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/The-Morning-Glory-Country-Cottage.h104070754.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/5b688022.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/b64100e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/d1f3492c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/9848b47e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### "The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington Farmington 10/10 Exceptional (10) "This is a darling house and very comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie B. CA $170 CA $321 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Farmington-Hotels-The-Hideaway-1-Charming-2-Bedroom-House-With-WiFi.h106406059.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/69561cb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/afc944e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/78bb621e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/90-cbee2cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cute and comfy bedroom with 1 queen bed/private bath Eminence 9.4/10 Exceptional (19) "Rebecca has a beautiful property, clean, pretty, and conveniently located." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karla E. CA $133 CA $174 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Eminence-Hotels-Cute-And-Comfy-1-Bedroom-With-1-Queen-Bedprivate-Bath.h88611645.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/664fb1e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/c0dd14ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/ee42fe11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/af94ed61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 82 Acre Hobby Farm with Lincoln Log Cabin De Soto 10/10 Exceptional (40) "We absolutely loved our stay! The property is as listed and super clean. The owner was very easy to work with, considerate and the personal touches she provided put our stay over the top." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marshall S. CA $200 CA $374 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/De-Soto-Hotels-82-Acre-Hobby-Farm-With-Lincoln-Log-Cabin.h73274691.Hotel-Information) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110070000/110066600/110066526/701aec9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/111000000/110070000/110066600/110066526/b16ce2c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/111000000/110070000/110066600/110066526/bccf3a61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/111000000/110070000/110066600/110066526/1198f66e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff Poplar Bluff 8.4/10 Very good (7) "Enjoyed our stay at Andy’s place! It had everything we needed. Beds were super comfy and the water pressure in the showers was great. Nice, safe location. Easy to get to/from places. Place has a garage which we used one evening during a rain storm but otherwise felt completely safe leaving our vehicle on driveway overnight. We didn’t get a chance to use the nice deck area with bbq grill but this is definitely a great feature of the property. The large tv in the living room was a hit with my... ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Holly R. CA $140 CA $356 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Poplar-Bluff-Hotels-Charming-2-Bedroom-House-With-2-KING-BEDS-In-Pleasant-Poplar-Bluff.h110066526.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/0cb5c163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h570x0y57-17016e83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h570x0y56-1ec5791d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h569x0y57-57bff386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Your home away from home in downtown, historic Farmington! Farmington 10/10 Exceptional (33) "Great place to rest a recoup for weekend activities " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matt B. CA $163 CA $297 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Farmington-Hotels-Your-Home-Away-From-Home-In-Downtown.h100465272.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070749/eb862a48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070749/d11c6960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070749/07dd57a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070749/cea618db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Doc's Cottage - A-Frame in Piggott, AR Piggott 10/10 Exceptional (8) "Great place to spend time with our daughter who lives in Piggott. The home was rustic and had all the amenities that was needed for an enjoyable stay.When your in the backyard it was secluded and quite even though you were in town." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy D. CA $168 CA $328 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Piggott-Hotels-Docs-Cottage-A-Frame-In-Piggott.h104070749.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/de7e2348.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/7b7b54ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/10599a29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/71aa8e7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided Greenville 10/10 Exceptional (4) "Cute, cozy, private getaway that you won't want to leave!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jade G. CA $213 CA $341 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Secluded-In-The-Woods.h89701234.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-05&endDate=2025-11-06®ionId=6058763&adults=2&location_highlights_explore=shopping&sort=RECOMMENDED&openPlayBack=true) ## Top Southeast Missouri Hotel Reviews ![Comfort Inn Festus - St Louis South](//images.trvl-media.com/lodging/1000000/50000/40200/40138/3ea7ebcc_y.jpg) ### Comfort Inn Festus - St Louis South 10/10 Excellent " Mika went above and beyond even getting us ice when we checked in. As I was checking out Gary fell out used.Mika got him up and inside. Got ice and bandages. We were soon on our way." [](https://expedia.ca/Farmington-Hotels-Comfort-Inn-Festus-St-Louis-South.h40138.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Clean. Happy hour at 530, decent breakfast options " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Candlewood Suites Cape Girardeau by IHG](//images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg) ### Candlewood Suites Cape Girardeau by IHG 10/10 Excellent "Clean room and bathroom, the beds and pillows were comfortable, the bathroom and the room were both really spacious which my toddler loved after being in her car seat she had plenty of room to run freely. The location was safe as well and convenient having a Rhodes close by open late to get snacks and chargers. I was pleased with my stay I felt safe and comfortable." [](https://expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Quality Inn](//images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg) ### Quality Inn 10/10 Excellent "It was so welcoming and peaceful" [](https://expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 10/10 Excellent "Room was a bit on the small side, but comfortable." [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](//images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 10/10 Excellent "The staff was very professional, kind and accommodating. " [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Close to the interstate so easy to get to when traveling. Nice property - plus that Outback Steakhouse is right next door for dining. We have stayed here numerous times over the years and always pleased. " [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](//images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 10/10 Excellent "One of the best hotel stays….. The staff was so friendly. They served warm cookies from 8-9 pm and a very nice breakfast until 10 am. Quiet and safe " [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [Cheap Hotels in Advance](https://www.expedia.ca/Advance-Hotels-Cheap-Hotels.0-0-d553248634983475122-tCheapHotels.Travel-Guide-Filter-Hotels) - [B&B in Annapolis](https://www.expedia.ca/Annapolis-Bed-And-Breakfast.d6282465-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels with Balconies in Annapolis](https://www.expedia.ca/Annapolis-Hotels-Hotels-With-Balconies.0-0-d6282465-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Annapolis](https://www.expedia.ca/Annapolis-Hotels-Luxury-Hotel.0-0-d6282465-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Annapolis](https://www.expedia.ca/Annapolis-Hotels-Spa-Hotel.0-0-d6282465-tSpaHotel.Travel-Guide-Filter-Hotels) - [Annapolis Hotels](https://www.expedia.ca/Annapolis-Hotels.d6282465.Travel-Guide-Hotels) - 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