Title: Book the Best Southeast Minnesota LUXURY Hotels - Upscale Hotels in Southeast Minnesota, MN | Expedia.ca [Southeast Minnesota Travel Guide](https://expedia.ca/Southeast-Minnesota.dx6233996)[Hotels in Southeast Minnesota](https://expedia.ca/Southeast-Minnesota-Hotels.d6233996.Travel-Guide-Hotels)[Vacation Rentals in Southeast Minnesota](https://expedia.ca/Southeast-Minnesota-Vacation-Rentals.d6233996.Travel-Guide-VacationRentals)[Flights to Southeast Minnesota](https://expedia.ca/Cheap-Flights-To-Southeast-Minnesota.d6233996.Travel-Guide-Flights)[Southeast Minnesota Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Minnesota.d6233996.Car-Rental-Guide)[Southeast Minnesota Vacation Packages](https://expedia.ca/Southeast-Minnesota.d6233996.Destination-Travel-Guides) ![Rochester showing a city and skyline](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63803-Rochester.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Southeast Minnesota, MN ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Minnesota Luxury Hotels Tonight [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=6233996&startDate=2025-10-30&endDate=2025-10-31&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=6233996&startDate=2025-10-31&endDate=2025-11-01&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6233996&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6233996&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Southeast Minnesota Luxury Hotels ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/f91e65d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/ecda08e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms | Living area](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/45535621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Grand Hotel Downtown Rochester 8.2/10 Very good (1701) "Great hotel close to everything convenient location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marta CA $170 CA $196 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/f8e4d672.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 indoor pools](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/6897f3e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/f78e7c09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Med City Inn & Suites - Mayo Clinic Area Kutzky Park 7.8/10 Good (1009) "Great staff, room was clean and location was great for our needs." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tim CA $101 CA $116 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/9000000/8150000/8145400/8145327/f7403b77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8145400/8145327/90ab369f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/9000000/8150000/8145400/8145327/9f9116a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/9000000/8150000/8145400/8145327/0269a226.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Northfield Northfield 8.2/10 Very good (614) "Loved the lobby area and the staff were very kind and friendly. Breakfast was good with a variety of choices. The pool and hot tub were also a welcome addition! I will definitely be staying here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lighann CA $141 CA $156 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Owatonna-Hotels-AmericInn-By-Wyndham-Northfield.h8145327.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/460000/459800/459757/f9d660c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/460000/459800/459757/70737bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, designer toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/460000/459800/459757/c00e3044.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459800/459757/c50d2d73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coratel Inn & Suites By Jasper Northfield Northfield 6.2/10 (642) "Parking was plentiful and easy." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kent CA $84 CA $93 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Owatonna-Hotels-Coratel-Inn-Suites-Northfield.h459757.Hotel-Information) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV, pay movies](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/9d7d5e02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/5e158908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/053999c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Inn and Suites - Mayo Clinic Area Downtown Rochester 8.0/10 Very good (1479) "Very friendly and helpful staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monte CA $172 CA $199 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/a518fccf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/abb2c83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/f77375e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Brentwood Inn & Suites Downtown Rochester 8.8/10 Excellent (1006) "Decent room, clean and friendly staff! Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Catherine CA $157 CA $181 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25400/25338/046c7ce7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25400/25338/ceaab958.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/25400/25338/95539a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/25400/25338/71dead3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Winona Winona 7.8/10 Good (1001) "Clean rooms, friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michele CA $77 CA $86 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Winona-Hotels-Days-Inn-By-Wyndham-Winona.h25338.Hotel-Information) ![Standard Room, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/43500/43416/c82aecae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/50000/43500/43416/90117589.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/43500/43416/2bd6f3e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/43500/43416/c992fc57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Regency Inn & Suites Faribault 7.4/10 Good (625) " Always a good stop" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $91 CA $118 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Owatonna-Hotels-Regency-Inn-Suites.h43416.Hotel-Information) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/3000000/2790000/2784600/2784519/7f955511.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/3000000/2790000/2784600/2784519/6e4e22cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/3000000/2790000/2784600/2784519/a0fb3319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/3000000/2790000/2784600/2784519/ffef9c0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Birch Hill Suite Rochester – Med City Rochester 6.8/10 (9) "I like that the property is close to the VA center where there is a bus stop. Just steps away. But this property had no phone in the room, I could not get Wyndham rewards, it's no longer they advertise free breakfast but that was not true. I" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly [](https://www.expedia.ca/Rochester-Hotels-Birch-Hill-Suite-Rochester-Med-City.h2784519.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/92dc90b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/31690353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/25e32575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/fca8e68c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aspen Select Rochester 8.4/10 Very good (1000) "Friendly staff. Nice rooms. Several good restaurants nearby. Convenient access to the hospital." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna CA $142 CA $172 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/Rochester-Hotels-Aspen-Select.h12245240.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15®ionId=6233996&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Southeast Minnesota Hotel Reviews ![Kahler Grand Hotel](//images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "clean room" [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![St James Hotel, a Historic Hotel of America](//images.trvl-media.com/lodging/1000000/10000/8900/8820/c90b9231_y.jpg) ### St James Hotel, a Historic Hotel of America 10/10 Excellent "Surprised how clean and nice room was for its age. No complaints!" [](https://expedia.ca/Red-Wing-Hotels-St-James-Hotel.h8820.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](//images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "Room was clean and quiet" [](https://expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74_y.jpg) ### Med City Inn & Suites - Mayo Clinic Area 10/10 Excellent "I stayed a week while my dad was at Mayo. If you arrive at night you may have to wait 30 minutes or more to check in, as they have very limited night staff. Good price, everything worked as it should. Lap pool, kiddie pool with slide & waterfall, jacuzzi, gym, laundry, etc. No complaints. " [](https://expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/10000/3600/3556/b33056f7_y.jpg) ### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area 10/10 Excellent "Everyone was great. Room was clean. They have a shuttle that runs to Mayo & surrounding areas which was real convenient for us. I have more appointments at Mayo so I will be staying there again. Great staff & House keeping :-)" [](https://expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent "So very convenient to Mayo buildings. Caribou, Jimmy Jones and Aisian food all right there. Friendly staff. " [](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](//images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "Clean room but lots of permanent stains on walls. Yet by far the best 2 star hotel I’ve stayed at. Need a place to crash and not worry about bugs? This is it! Look no further. " [](https://expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys](//images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c_y.jpg) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys 10/10 Excellent "everything was great! friendly staff, great breakfast!" [](https://expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) ![Aspen Select](//images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/92dc90b5_y.jpg) ### Aspen Select 10/10 Excellent "Friendly staff. Nice rooms. Several good restaurants nearby. Convenient access to the hospital." 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