Title: Book the Best Southeast Iowa WINERY Hotels in 2026 | Expedia.ca [Southeast Iowa Travel Guide](https://expedia.ca/Southeast-Iowa.dx6234151)[Hotels in Southeast Iowa](https://expedia.ca/Southeast-Iowa-Hotels.d6234151.Travel-Guide-Hotels)[Vacation Rentals in Southeast Iowa](https://expedia.ca/Southeast-Iowa-Vacation-Rentals.d6234151.Travel-Guide-VacationRentals)[Flights to Southeast Iowa](https://expedia.ca/Cheap-Flights-To-Southeast-Iowa.d6234151.Travel-Guide-Flights)[Southeast Iowa Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Iowa.d6234151.Car-Rental-Guide)[Southeast Iowa Vacation Packages](https://expedia.ca/Southeast-Iowa.d6234151.Destination-Travel-Guides) ![Found this bridge while exploring. It used to be a railroad bridge, transformed to a buggy bridge, and not after restoration is a walking path bridge. It stretches over a hundred feet and while walking you can still see the old railroad and boards for the buggy. ](https://images.trvl-media.com/place/6052570/9ddd26bd-82be-41a2-94d7-8f1f7c77e19f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michael Schuier # Find Winery Hotels in Southeast Iowa from CA $98 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Iowa Winery Hotels Tonight [Dec 21 - Dec 22](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-12-21&endDate=2025-12-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 22 - Dec 23](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-12-22&endDate=2025-12-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southeast Iowa hotels with winery ![Reception](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/29eea63f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/4c1852e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/0665e0f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/f0df8156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Mount Pleasant [](https://www.expedia.ca/Burlington-Hotels-Quality-Inn-Suites.h68135.Hotel-Information) Mount Pleasant 8.0/10 Very good (115) "The staff were absolutely great!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacob CA $87 CA $98 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Burlington-Hotels-Quality-Inn-Suites.h68135.Hotel-Information) ![Water park](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/3ad09b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/3d54b27e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/c12d27ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/f77198ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fun City Resort Hotel [](https://www.expedia.ca/Burlington-Hotels-The-PZAZZ-Resort-Hotel.h1803337.Hotel-Information) Burlington 8.4/10 Very good (296) "Room was great — Every staff member we came in contact with was extremely courteous & helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan [](https://www.expedia.ca/Burlington-Hotels-The-PZAZZ-Resort-Hotel.h1803337.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/23000000/22870000/22869300/22869218/529310eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22870000/22869300/22869218/68155d5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/23000000/22870000/22869300/22869218/b53eee52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/23000000/22870000/22869300/22869218/323ba42b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Relax on the River and Enjoy Southeast Iowa's Beauty [](https://www.expedia.ca/Keosauqua-Hotels-Relax-On-The-River-And-Enjoy-Southeast-Iowas-Beauty.h22869218.Hotel-Information) Keosauqua 9.8/10 Exceptional (170) "Very quiet beautiful cabin had everything we needed for a relaxing weekend. We really enjoyed the screened in back porch and fire pit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erin S. CA $159 CA $249 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Keosauqua-Hotels-Relax-On-The-River-And-Enjoy-Southeast-Iowas-Beauty.h22869218.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/64d77fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/c269f6aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/e818ffac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/5404cbe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Red Front Suite - Sleeps 15 [](https://www.expedia.ca/Nauvoo-Hotels-The-Red-Front-Suite-Sleeps-15.h39192154.Hotel-Information) Nauvoo 9.8/10 Exceptional (85) "Great location, comfortable beds." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diane P. CA $90 CA $224 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/Nauvoo-Hotels-The-Red-Front-Suite-Sleeps-15.h39192154.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/112000000/111040000/111035700/111035699/0c561263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111040000/111035700/111035699/9bb0b7d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111040000/111035700/111035699/c8f8590c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111040000/111035700/111035699/aba0f90d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nauvoo Windmill Farmhouse 10-12 people [](https://www.expedia.ca/Niota-Hotels-Nauvoo-Windmill-Farmhouse.h111035699.Hotel-Information) Niota 10/10 Exceptional (10) "The check-in was pretty easy and the kitchen had everything we needed to make quick meals. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tony H. CA $93 CA $216 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Niota-Hotels-Nauvoo-Windmill-Farmhouse.h111035699.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/84000000/83550000/83542100/83542038/dbc638da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/84000000/83550000/83542100/83542038/w506h639x260y44-f1ec642a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/84000000/83550000/83542100/83542038/w506h683x259y0-68106b1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/84000000/83550000/83542100/83542038/79ee4c6e_edited_42c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairy Bowery [](https://www.expedia.ca/Nauvoo-Hotels-Fairy-Bowery.h83542038.Hotel-Information) Nauvoo 8.4/10 Very good (55) "Such a quaint little stay! The property has so much character and charm! Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Camry CA $94 CA $129 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Nauvoo-Hotels-Fairy-Bowery.h83542038.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/113000000/112110000/112101200/112101176/0beb6801.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, DVD player](https://images.trvl-media.com/lodging/113000000/112110000/112101200/112101176/61737845.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112110000/112101200/112101176/w2560h3373x0y40-2a6f02c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112110000/112101200/112101176/b0aa0631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### A four bedroom hobbit hole style home five minutes from historic Nauvoo Illinois [](https://www.expedia.ca/Nauvoo-Hotels-A-Four-Bedroom-Hobbit-Hole-Style-Home-Five-Minutes-From-Historic-Nauvoo-Illinois.h112101176.Hotel-Information) Nauvoo 10/10 Exceptional (8) "Loved the house it was so cute and fun. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey CA $345 CA $442 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Nauvoo-Hotels-A-Four-Bedroom-Hobbit-Hole-Style-Home-Five-Minutes-From-Historic-Nauvoo-Illinois.h112101176.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/fb837b6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/f04272de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/58cc1522.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/af7886e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Experience Beautiful Pioneer Home In Nauvoo! [](https://www.expedia.ca/Nauvoo-Hotels-Experience-Beautiful-Pioneer-Home-In-Nauvoo.h42641186.Hotel-Information) Nauvoo 9.8/10 Exceptional (76) "Authentic feel with modern day convenient items. Fun house with rich history. Would definitely stay again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jared T. CA $262 CA $527 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Nauvoo-Hotels-Experience-Beautiful-Pioneer-Home-In-Nauvoo.h42641186.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/e15b71d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/00124c26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/c8a07f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/8f36affe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Johnston Mansion Bed and Breakfast price shown is Vrbo Mansion price [](https://www.expedia.ca/Keokuk-Hotels-Johnston-Mansion-Bed-And-Breakfast-Price-Shown-Is-Vrbo-Mansion-Price.h23611929.Hotel-Information) Keokuk 9.0/10 Wonderful (2) "Beautiful place in lovely, walkable neighborhood near the Mississippi. The hosts couldn't have been more accommodating or kind." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathryn C. CA $1,656 CA $2,566 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Keokuk-Hotels-Johnston-Mansion-Bed-And-Breakfast-Price-Shown-Is-Vrbo-Mansion-Price.h23611929.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/105000000/104410000/104401900/104401880/b8c2dd9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/105000000/104410000/104401900/104401880/69a89a16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/105000000/104410000/104401900/104401880/b3f667c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/105000000/104410000/104401900/104401880/ad76718f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wine & Vinyl Vacation Home \~ Wine, Vinyl Records, Popcorn Machine, Private Deck [](https://www.expedia.ca/Wine-Vinyl-Vacation-Home-Wine.h104401880.Hotel-Information) Tennessee 8.8/10 Excellent (13) "Clean and secluded. The only issue we had was not being able to obtain wifi password for a zoom meeting we had scheduled. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert F. CA $109 CA $266 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Wine-Vinyl-Vacation-Home-Wine.h104401880.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-04&endDate=2026-01-05®ionId=6234151&adults=2&location_highlights_explore=winery&sort=RECOMMENDED&openPlayBack=true) ## Top Southeast Iowa Hotel Reviews ![Quality Inn & Suites Fort Madison near Hwy 61](https://images.trvl-media.com/lodging/1000000/970000/966600/966544/28d171d7_y.jpg) ### Quality Inn & Suites Fort Madison near Hwy 61 10/10 Excellent "Quiet, large parking lot, restaurant next door, free breakfast was good, hot tub and pool very nice. " [](https://expedia.ca/Burlington-Hotels-Quality-Inn-Suites-Fort-Madison-Near-Hwy-61.h966544.Hotel-Information) ![Cobblestone Inn & Suites - Fort Madison](https://images.trvl-media.com/lodging/10000000/9540000/9534800/9534717/ef5745b9_y.jpg) ### Cobblestone Inn & Suites - Fort Madison 10/10 Excellent "One of the nicer stays we have experienced. Great clean room and breakfast. Helpful staff." [](https://expedia.ca/Burlington-Hotels-Cobblestone-Inn-Suites-Fort-Madison.h9534717.Hotel-Information) ![The Inn at Old Nauvoo](https://images.trvl-media.com/lodging/4000000/3160000/3151900/3151830/w1899h1230x0y0-2f3f93ff_y.jpg) ### The Inn at Old Nauvoo 10/10 Excellent "Clean room and friendly staff " [](https://expedia.ca/Nauvoo-Hotels-Nauvoo-Family-Inn-And-Suites.h3151830.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [5 Star Hotels in Central United States ](https://www.expedia.ca/5Star-Central-United-States-Hotels.s50-0-d6209877.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Quad Cities ](https://www.expedia.ca/5Star-Quad-Cities-Hotels.s50-0-d603001.Travel-Guide-Filter-Hotels) - [Farmstay in Central United States ](https://www.expedia.ca/Central-United-States-Agritourism.d6209877-aaAgritourism.Travel-Guide-Accommodation) - [B&B in Central United States ](https://www.expedia.ca/Central-United-States-Bed-And-Breakfast.d6209877-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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