Title: Book the Best Southeast Iowa WINERY Hotels in 2025 | Expedia.ca [Southeast Iowa Travel Guide](https://expedia.ca/Southeast-Iowa.dx6234151)[Hotels in Southeast Iowa](https://expedia.ca/Southeast-Iowa-Hotels.d6234151.Travel-Guide-Hotels)[Vacation Rentals in Southeast Iowa](https://expedia.ca/Southeast-Iowa-Vacation-Rentals.d6234151.Travel-Guide-VacationRentals)[Flights to Southeast Iowa](https://expedia.ca/Cheap-Flights-To-Southeast-Iowa.d6234151.Travel-Guide-Flights)[Southeast Iowa Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Iowa.d6234151.Car-Rental-Guide)[Southeast Iowa Vacation Packages](https://expedia.ca/Southeast-Iowa.d6234151.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/55b2c6dee1b7995ed1033756cd63ca06.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Winery Hotels in Southeast Iowa - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Iowa Winery Hotels Tonight [Nov 2 - Nov 3](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-11-02&endDate=2025-11-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 3 - Nov 4](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-11-03&endDate=2025-11-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southeast Iowa Winery Hotels ![Reception](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/29eea63f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/4c1852e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/f0df8156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/645101d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Mount Pleasant 7.8/10 Good (105) "Staff was very helpful and friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony CA $88 CA $99 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Burlington-Hotels-Quality-Inn-Suites.h68135.Hotel-Information) ![Water park](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/3ad09b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/c12d27ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/3d54b27e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/f77198ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fun City Resort Hotel Burlington 8.4/10 Very good (290) "This was kid friendly and there were options for the kids and adults to be entertained. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dana [](https://www.expedia.ca/Burlington-Hotels-The-PZAZZ-Resort-Hotel.h1803337.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8520000/8512100/8512062/b7f01cc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8520000/8512100/8512062/dcd82ad5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Ellen's Orchard)](https://images.trvl-media.com/lodging/9000000/8520000/8512100/8512062/f324bf76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Beth's Forest)](https://images.trvl-media.com/lodging/9000000/8520000/8512100/8512062/43a16142.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nauvoo Grand Bed & Breakfast Nauvoo 8.8/10 Excellent (119) "Host is very friendly and welcoming! Our room was Very comfortable, quiet, clean, fun, I will definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller CA $244 CA $275 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Nauvoo-Hotels-Nauvoo-Grand-Bed-Breakfast.h8512062.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/23000000/22870000/22869300/22869218/529310eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/23000000/22870000/22869300/22869218/740564b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22870000/22869300/22869218/68155d5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/23000000/22870000/22869300/22869218/b53eee52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Relax on the River and Enjoy Southeast Iowa's Beauty Keosauqua 9.8/10 Exceptional (169) "Overnight stay with friend to enjoy peace and rest. Small rustic cabin on the river was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terri D. CA $161 CA $253 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Keosauqua-Hotels-Relax-On-The-River-And-Enjoy-Southeast-Iowas-Beauty.h22869218.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/84000000/83550000/83542100/83542038/dbc638da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/84000000/83550000/83542100/83542038/79ee4c6e_edited_42c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/84000000/83550000/83542100/83542038/w506h683x259y0-68106b1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/84000000/83550000/83542100/83542038/4eee3559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairy Bowery Nauvoo 8.4/10 Very good (54) "We had a great stay in the Fairy Bowery! On the website it has a single bed listed in the bedroom, we were happy to see it was a bunk bed! We had a great stay and the host was very accommodating. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura P. CA $95 CA $130 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Nauvoo-Hotels-Fairy-Bowery.h83542038.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/112000000/111040000/111035700/111035699/0c561263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111040000/111035700/111035699/9bb0b7d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111040000/111035700/111035699/aba0f90d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111040000/111035700/111035699/c8f8590c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nauvoo Windmill Farmhouse 10-12 people Niota 10/10 Exceptional (10) "Clean and well kept. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Justin M. CA $126 CA $255 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Niota-Hotels-Nauvoo-Windmill-Farmhouse.h111035699.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/113000000/112110000/112101200/112101176/0beb6801.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112110000/112101200/112101176/b0aa0631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, DVD player](https://images.trvl-media.com/lodging/113000000/112110000/112101200/112101176/b5fb8983.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112110000/112101200/112101176/w2560h3373x0y40-2a6f02c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### A four bedroom hobbit hole style home five minutes from historic Nauvoo Illinois Nauvoo 10/10 Exceptional (8) "We enjoyed our stay in the halfling house. My husband and I and our 8 kids filled the space. It is themed very well and will stocked. We stayed only 1 night as we were passing through and my kids loved it! There are costumes to dress up in and even an old fashioned key that unlocks the round door. I will be recommending this cute house to everyone! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacey M. CA $350 CA $450 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Nauvoo-Hotels-A-Four-Bedroom-Hobbit-Hole-Style-Home-Five-Minutes-From-Historic-Nauvoo-Illinois.h112101176.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/64d77fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/5404cbe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/c269f6aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/385360d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Red Front Suite - Sleeps 15 Nauvoo 9.8/10 Exceptional (82) "Wonderful stay! Would definitely stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve CA $91 CA $228 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Nauvoo-Hotels-The-Red-Front-Suite-Sleeps-15.h39192154.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/fb837b6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/58cc1522.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/af7886e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/f04272de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Experience Beautiful Pioneer Home In Nauvoo! Nauvoo 10/10 Exceptional (75) "We had a wonderful anniversary trip to Nauvoo. The historic and quaint Mix House added some period charm to our stay. While the house retains much of its 19th century charm, it has the modern conveniences needed for a relaxing stay. It may have been the off season, but food and meal choices were limited in Nauvoo itself. We were grateful for the items we ordered from The Apron Bake Shoppe." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul P. CA $266 CA $535 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Nauvoo-Hotels-Experience-Beautiful-Pioneer-Home-In-Nauvoo.h42641186.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/e15b71d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/8f36affe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/00124c26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/c8a07f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Johnston Mansion Bed and Breakfast price shown is Vrbo Mansion price Keokuk 9.0/10 Wonderful (2) "Beautiful place in lovely, walkable neighborhood near the Mississippi. The hosts couldn't have been more accommodating or kind." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathryn C. CA $1,681 CA $2,688 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Keokuk-Hotels-Johnston-Mansion-Bed-And-Breakfast-Price-Shown-Is-Vrbo-Mansion-Price.h23611929.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-16&endDate=2025-11-17®ionId=6234151&adults=2&location_highlights_explore=winery&sort=RECOMMENDED&openPlayBack=true) ## Top Southeast Iowa Hotel Reviews ![Cobblestone Inn & Suites - Fort Madison](//images.trvl-media.com/lodging/10000000/9540000/9534800/9534717/ef5745b9_y.jpg) ### Cobblestone Inn & Suites - Fort Madison 10/10 Excellent "Excellent Place to stay! Rooms great, beds comfortable, breakfast good. They do have 2 stories and no elevator, just ask for ground floor if you have problems with stairs." [](https://expedia.ca/Burlington-Hotels-Cobblestone-Inn-Suites-Fort-Madison.h9534717.Hotel-Information) ![The Inn at Old Nauvoo](//images.trvl-media.com/lodging/4000000/3160000/3151900/3151830/w1899h1230x0y0-2f3f93ff_y.jpg) ### The Inn at Old Nauvoo 10/10 Excellent "Clean room and friendly staff " [](https://expedia.ca/Nauvoo-Hotels-Nauvoo-Family-Inn-And-Suites.h3151830.Hotel-Information) ![Quality Inn & Suites Fort Madison near Hwy 61](//images.trvl-media.com/lodging/1000000/970000/966600/966544/28d171d7_y.jpg) ### Quality Inn & Suites Fort Madison near Hwy 61 10/10 Excellent "Very clean place. Good services and super friendly. Definitely we are planning to come back to this hotel. 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