Title: Book the Best South San Diego LUXURY Hotels - Upscale Hotels in South San Diego, CA | Expedia.ca

[South San Diego Travel Guide](https://expedia.ca/South-San-Diego.dx553248632063518562)[Hotels in South San Diego](https://expedia.ca/South-San-Diego-Hotels.d553248632063518562.Travel-Guide-Hotels)[Vacation Rentals in South San Diego](https://expedia.ca/South-San-Diego-Vacation-Rentals.d553248632063518562.Travel-Guide-VacationRentals)[Flights to South San Diego](https://expedia.ca/Cheap-Flights-To-South-San-Diego.d553248632063518562.Travel-Guide-Flights)[Things to do in South San Diego](https://expedia.ca/Things-To-Do-In-South-San-Diego.d553248632063518562.Travel-Guide-Activities)[South San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-South-San-Diego.d553248632063518562.Car-Rental-Guide)[South San Diego Vacation Packages](https://expedia.ca/South-San-Diego.d553248632063518562.Destination-Travel-Guides)

![Captured this guy doing a wheelie during a beautiful sunset! #imperialbeach #EndlessSummer #autographhotels #Marriott #piersouthresort](https://images.trvl-media.com/place/177683/d4a8a1a3-bd23-4c6a-826e-e0c1c12dddaa.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Karen Leone

# Find luxury hotels in South San Diego, CA

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## Check availability on South San Diego Luxury Hotels

Tonight

[Jan 7 - Jan 8](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2026-01-07&endDate=2026-01-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Jan 8 - Jan 9](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2026-01-08&endDate=2026-01-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

This weekend

[Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2026-01-09&endDate=2026-01-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2026-01-16&endDate=2026-01-18&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Our top choices for South San Diego luxury hotels

![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/4cbc3cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![On the beach, surfing](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/605f04db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/e7aa7734.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/c1170013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pier South Resort, Autograph Collection by Marriott

[](https://www.expedia.ca/Imperial-Beach-Hotels-Pier-South-Resort.h570818.Hotel-Information)

Imperial Beach

8.4/10

Very good

(1005)

"Room was beautiful, everything about my stay was perfect."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Victoria

CA $234

CA $298 total

includes taxes & fees

Jan 9 - Jan 10

[](https://www.expedia.ca/Imperial-Beach-Hotels-Pier-South-Resort.h570818.Hotel-Information)

![Water park](https://images.trvl-media.com/lodging/112000000/111760000/111750800/111750749/47291b9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/112000000/111760000/111750800/111750749/82c4a42f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bars/lounges, sports bar](https://images.trvl-media.com/lodging/112000000/111760000/111750800/111750749/b994d889.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/112000000/111760000/111750800/111750749/2812f1c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Gaylord Pacific Resort & Convention Center

[](https://www.expedia.ca/Chula-Vista-Hotels-Gaylord-Pacific-Resort-Convention-Center.h111750749.Hotel-Information)

Chula Vista

8.2/10

Very good

(223)

"Beautiful hotel I enjoyed myself"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Grace

CA $399

CA $518 total

includes taxes & fees

Jan 9 - Jan 10

[](https://www.expedia.ca/Chula-Vista-Hotels-Gaylord-Pacific-Resort-Convention-Center.h111750749.Hotel-Information)

![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/900/858/543624c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Corner](https://images.trvl-media.com/lodging/1000000/10000/900/858/721ac3a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/10000/900/858/c095adf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/10000/900/858/c6795882.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency Mission Bay Spa and Marina

[](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-Mission-Bay-Spa-And-Marina.h858.Hotel-Information)

Mission Bay

8.4/10

Very good

(1597)

"Great staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Samuel

CA $198

CA $300 total

includes taxes & fees

Jan 20 - Jan 21

[](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-Mission-Bay-Spa-And-Marina.h858.Hotel-Information)

![Outdoor pool, open 7:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/b5f2a64d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/24eddfb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/4c453903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/de48676b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Diego Mission Bay Resort

[](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Mission-Bay-Resort.h25598.Hotel-Information)

Mission Bay

8.4/10

Very good

(1331)

"Loved the bay front room with the large grass area right out the door!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Todd and Danielle

CA $210

CA $315 total

includes taxes & fees

Feb 2 - Feb 3

[](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Mission-Bay-Resort.h25598.Hotel-Information)

![5 outdoor pools, a heated pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/d0f041ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed (Bayside Bungalow Bay) | Living area](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/2fecbf54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/bc1e5add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; Californian cuisine](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/7fe47de0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Paradise Point Resort & Spa

[](https://www.expedia.ca/San-Diego-Hotels-Paradise-Point-Resort-Spa.h3731.Hotel-Information)

Mission Bay

8.6/10

Excellent

(2376)

"Great facility and amenities. We look forward to taking our family back again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andy

CA $152

CA $248 total

includes taxes & fees

Jan 19 - Jan 20

[](https://www.expedia.ca/San-Diego-Hotels-Paradise-Point-Resort-Spa.h3731.Hotel-Information)

![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/22ecf276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/250333ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/3bb415c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/700997bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sycuan Casino Resort

[](https://www.expedia.ca/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information)

El Cajon

9.2/10

Wonderful

(1663)

"Very clean resort. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Petrina

[](https://www.expedia.ca/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2d82864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/05a7ba66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cafe](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/d6929efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/97863ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Loews Coronado Bay Resort

[](https://www.expedia.ca/Coronado-Hotels-Loews-Coronado-Bay-Resort.h25840.Hotel-Information)

Silver Strand

8.8/10

Excellent

(1062)

"The staff and amenities were spectacular. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andrew

CA $275

CA $373 total

includes taxes & fees

Jan 8 - Jan 9

[](https://www.expedia.ca/Coronado-Hotels-Loews-Coronado-Bay-Resort.h25840.Hotel-Information)

![3 bars/lounges, lobby lounge, cocktail bar, cocktail bar](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/ce2dc6d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/fd80224d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, minibar, desk](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/8ea4f9d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/abbee14b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lafayette Hotel & Club

[](https://www.expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information)

University Heights

9.4/10

Exceptional

(1392)

"Amazing hotel, great staff and awesome food!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

michael

CA $316

CA $363 total

includes taxes & fees

Jan 8 - Jan 9

[](https://www.expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/717df324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/239995d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/b197cd41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/8399b5a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency La Jolla

[](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-La-Jolla.h21891.Hotel-Information)

University City

8.8/10

Excellent

(1002)

"Really clean room, comfortable towels, would definitely come back!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Samuel

CA $187

CA $266 total

includes taxes & fees

Jan 9 - Jan 10

[](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-La-Jolla.h21891.Hotel-Information)

![Junior Suite, 2 Queen Beds, Ocean View](https://images.trvl-media.com/lodging/1000000/20000/11600/11528/8f620308.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite (Pacific Sunset)](https://images.trvl-media.com/lodging/1000000/20000/11600/11528/cc0368c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/11600/11528/c1889f03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite (Pacific Sunset) | View from room](https://images.trvl-media.com/lodging/1000000/20000/11600/11528/29e330c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pacific Terrace Hotel

[](https://www.expedia.ca/San-Diego-Hotels-Pacific-Terrace-Hotel.h11528.Hotel-Information)

Pacific Beach

9.6/10

Exceptional

(1002)

"Great location, room amenities and staff"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Cristina Iuliana

CA $260

CA $299 total

includes taxes & fees

Jan 20 - Jan 21

[](https://www.expedia.ca/San-Diego-Hotels-Pacific-Terrace-Hotel.h11528.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-21&endDate=2026-01-22&regionId=553248632063518562&adults=2&sort=LUXURY&star=40,50&openPlayBack=true)

## Top South San Diego Hotel Reviews

![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg)

### Sheraton San Diego Resort

10/10 Excellent

"From the moment we check in the staff was always courteous and attentive to all of our needs. We were even given a wonderful surprise from the Hotel delivered to our suite, a bottle of champagne and desert."

[](https://expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Resort.h11109.Hotel-Information)

![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg)

### Hard Rock Hotel San Diego

10/10 Excellent

"great"

[](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information)

![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg)

### Bay Club Hotel & Marina

10/10 Excellent

"Beautiful views from room 248! Great service throughout our stay from all the departments! Quiet, serenely quiet which we really enjoyed. Everything was clean, spacious, kept up and easy to navigate."

[](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information)

![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg)

### The Dana on Mission Bay

10/10 Excellent

"excellent service and staff. nice hotel "

[](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information)

![Days Inn by Wyndham San Diego Hotel Circle](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg)

### Days Inn by Wyndham San Diego Hotel Circle

10/10 Excellent

"Good and clean"

[](https://expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information)

![Marriott Marquis San Diego Marina](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/9078a9ee_y.jpg)

### Marriott Marquis San Diego Marina

10/10 Excellent

"The room was great, great views of the city and marina. Location is great. Overall I’d recommend this hotel. Brought my girl for a weekend getaway and we both loved it. "

[](https://expedia.ca/San-Diego-Hotels-Marriott-Marquis-San-Diego-Marina.h24394.Hotel-Information)

![Best Western Plus Marina Gateway Hotel](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg)

### Best Western Plus Marina Gateway Hotel

10/10 Excellent

"Could have drain the tub better . But either then that I enjoy my stay. Always come back to this location. "

[](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information)

![San Diego Mission Bay Resort](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/bbcdbd6d_y.jpg)

### San Diego Mission Bay Resort

10/10 Excellent

"Loved the bay front room with the large grass area right out the door!"

[](https://expedia.ca/San-Diego-Hotels-San-Diego-Mission-Bay-Resort.h25598.Hotel-Information)

![The DEXTRO Little Italy, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd_y.jpg)

### The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent

"Yes "

[](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information)

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