Title: South San Diego Guest Houses | Expedia.ca [South San Diego Travel Guide](https://expedia.ca/South-San-Diego.dx553248632063518562)[Hotels in South San Diego](https://expedia.ca/South-San-Diego-Hotels.d553248632063518562.Travel-Guide-Hotels)[Vacation Rentals in South San Diego](https://expedia.ca/South-San-Diego-Vacation-Rentals.d553248632063518562.Travel-Guide-VacationRentals)[Flights to South San Diego](https://expedia.ca/Cheap-Flights-To-South-San-Diego.d553248632063518562.Travel-Guide-Flights)[Things to do in South San Diego](https://expedia.ca/Things-To-Do-In-South-San-Diego.d553248632063518562.Travel-Guide-Activities)[South San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-South-San-Diego.d553248632063518562.Car-Rental-Guide)[South San Diego Vacation Packages](https://expedia.ca/South-San-Diego.d553248632063518562.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/1577a5f9f9b33dbc18377fc367dd66b8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Guest Houses in South San Diego ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2025-11-07&endDate=2025-11-09&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2025-11-14&endDate=2025-11-16&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2025-11-28&endDate=2025-11-30&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2025-12-26&endDate=2025-12-28&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select South San Diego Guest Houses ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/40601c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/06ca5233.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/665db20b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/1dcb5057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Primero Hotel Chula Vista 9.2/10 Wonderful (1001) "I stayed in town by myself for two nights and felt very safe there. A very charming place to stay and charming people! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sierra CA $118 CA $130 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Chula-Vista-Hotels-El-Primero-Hotel.h1630286.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/da8f2406.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/aea9aa0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/f6cdb0c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/6d6bdbe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vineyard Hacienda Spring Valley 9.2/10 Wonderful (527) "Beautiful place, kind staff. We are glad we found this place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Allison CA $171 CA $185 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Spring-Valley-Hotels-Vineyard-Hacienda.h8782409.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/98000000/97080000/97072000/97071912/e31fedb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/98000000/97080000/97072000/97071912/8cd6366e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/98000000/97080000/97072000/97071912/244ce47e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/98000000/97080000/97072000/97071912/3c17e09a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy 1-bed, 1-bath, kitchenette Guest House in San Diego. Mount Hope 10/10 Exceptional (43) "It was in a convenient location, clean and had everything we needed. Perfect for two people! We would stay here again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dillon H. CA $119 CA $265 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Diego-Hotels-Cozy-1-Bed.h97071912.Hotel-Information) ![1 bedroom, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/70000000/69870000/69864700/69864680/08b97f4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/70000000/69870000/69864700/69864680/115feff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/70000000/69870000/69864700/69864680/b5618207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/70000000/69870000/69864700/69864680/8e9fa372.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hidden King Suite with Garden, Parking - 4 Guest La Mesa 10/10 Exceptional (18) "Great for short stays" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason CA $104 CA $323 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/La-Mesa-Hotels-Hidden-King-Suite-With-Garden.h69864680.Hotel-Information) ![Fridge, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/aca60f31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/12d034a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/3f572155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/f3ceca19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heart of SD | Zoo Nearby | Private Patio | Central Mid-City 8.0/10 Very good (4) "Such a great spot for a little getaway! A Cozy room with everything you need to enjoy your vacation stressfree. I would definitely stay here again in the future!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zackery B. CA $126 CA $282 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/San-Diego-Hotels-Modern-Gem-Private-Patio-Central-Heart-Of-SD.h100222473.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/104000000/103800000/103798000/103797959/5fca1b4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/104000000/103800000/103798000/103797959/6477ec50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103800000/103798000/103797959/af1e19ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/104000000/103800000/103798000/103797959/b366aa2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Escape | Modern 2BR w/ PrivateOutdoorLounge Bay Park 8.8/10 Excellent (5) "We had a great weekend here! The location is perfect and the host was very friendly and communicative. We thoroughly enjoyed our time here with our family." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley F. CA $155 CA $332 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/San-Diego-Hotels-BayFront-BackyardCozyCloseToSeaworldCloseToOcean.h103797959.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32420000/32415000/32414919/07444ca0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/33000000/32420000/32415000/32414919/270-3009c275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, travel crib, WiFi](https://images.trvl-media.com/lodging/33000000/32420000/32415000/32414919/270-ba76d170.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/33000000/32420000/32415000/32414919/270-d7901b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Perfectly located, Modern, custom built casita w/AC & rooftop igloo sunset deck University Heights 10/10 Exceptional (64) "Great unit, close driving distance to many tourist sites. Walking distance to a few restaurants and bars on Park. Fantastic water pressure for the shower! Lots of beach and kid-friendly gear provided. Would definitely recommend and would stay here again when I return " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy CA $278 CA $484 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/San-Diego-Hotels-Perfectly-Located.h32414919.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/5afb3714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/3f8053a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/6e926ef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/514bc114.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Newly Built Guest Home Mira Mesa 10/10 Exceptional (35) "Spotless, nice location, and great host." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Akiko J. CA $378 CA $741 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/San-Diego-Hotels-Newly-Built-Guest-Home.h91135120.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/198e6a6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/505cfdc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/89729cf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/3706623f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rockaway North - Family Friendly, Garage Parking & Laundry Mission Beach 9.8/10 Exceptional (26) "It was the perfect little getaway for our family. The apartment apartment is small but very efficient and the property managers were awesome about their communication with us as we were checking in and getting stuff for our kids. We really appreciate it. The effort that the owners put into the space the bed was comfortable. The shower was awesome. Appliances and cookware new and ready to use. And best of all just steps from the beach as advertised. We would would happily return and hope that... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexander C. CA $237 CA $547 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/San-Diego-Hotels-Rockaway-North-Family-Friendly.h92449548.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-13&endDate=2025-11-14®ionId=553248632063518562&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-San-Diego-Guest-Houses.d553248632063518562-aaGuestHouses.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-San-Diego-Guest-Houses.d553248632063518562-aaGuestHouses.Travel-Guide-Accommodation) ## Top South San Diego Hotel Reviews ![DoubleTree by Hilton Hotel San Diego - Mission Valley](//images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "The staff was friendly. The rooms were clean. It had a great bar and outdoor area to relax. " [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Sheraton San Diego Resort](//images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "I don’t know where to start. From the shuttle in to the shuttle out, everything was perfect!" [](https://expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) ![Kings Inn San Diego](//images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "All of the above" [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](//images.trvl-media.com/lodging/1000000/20000/13300/13205/0339a25b_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Balcony view and healthy breakfast! Excellent customer service!" [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![Comfort Inn San Diego Airport At The Harbor](//images.trvl-media.com/lodging/1000000/10000/8800/8727/17ffc972_y.jpg) ### Comfort Inn San Diego Airport At The Harbor 10/10 Excellent "Short walk to the Harbor Walk and eateries. Parking may be challenging. The pool deck and pool were clean and inviting. Busy street, there will be noise. " [](https://expedia.ca/San-Diego-Hotels-Comfort-Inn-San-Diego-Airport-At-The-Harbor.h8727.Hotel-Information) ![Bay Club Hotel & Marina](//images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Will definitely stay here again" [](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Wyndham Garden San Diego Near SeaWorld](//images.trvl-media.com/lodging/1000000/50000/41000/40962/76b78879_y.jpg) ### Wyndham Garden San Diego Near SeaWorld 10/10 Excellent "The staff were friendly. The room was clean but there were some issues in the room. Shower head was not completely sealed. There there spots on the ceiling in the bathroom and the some baseboards were messed up. " [](https://expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) ![Hampton Inn & Suites by Hilton San Diego SeaWorld](//images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/cc52443d_y.jpg) ### Hampton Inn & Suites by Hilton San Diego SeaWorld 10/10 Excellent "A nice, clean Hampton Inn. Everything that you would expect" [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "An excellent classic beachfront hotel. We have visited the property for several years, but this is the first time that we stayed in the hotel. It lived up to all of our expectations. Located on the famous Coronado Beach, the hotel offers six different dining alternatives, each maintaining a distinctive focus and personality. Loved Nobu in particular. Nice shops. Amazing beach!!" [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ## Find out more about South San Diego ## South San Diego Guest Houses information | Number of reviews | | | --- | --- | | Accommodation | Guest Houses | | Lowest Price | | | Highest Price | | ## Frequently asked questions ### What is the nightly rate for a guest house in South San Diego? > Rates for South San Diego guest houses vary, but travelers can find great-value prices with Expedia. A range of factors can affect nightly rates, such as the location, the breakfast offering, and the range of amenities. Travelers looking for a good deal should consider looking for a midweek stay, as weekend rates at South San Diego guest houses tend to be higher. Remember to also use our filters to sort prices from low to high. ### What's the difference between a South San Diego guest house and a B&B? > A guest house in South San Diego is typically a larger establishment with more rooms, offering a more hotel-like experience, and may provide additional amenities including luxury bedding. In contrast, a B&B is usually a smaller property that focuses primarily on providing a room and breakfast. A B&B is often more personal, and breakfast is typically included as part of the stay, but other services might be more limited compared to a guest house. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Hotels near Beyer Blvd Trolley Station](https://www.expedia.ca/Beyer-Blvd-Trolley-Station-Hotels.d6186828.Travel-Guide-Hotels) - [Camino Real Hotels in Castle Park](https://www.expedia.ca/Castle-Park-Chula-Vista-Hotels-Camino-Real.0-n177686-0--bCaminoReal.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Castle Park](https://www.expedia.ca/Castle-Park-Chula-Vista-Hotels-Couples-Resorts-Hotels.0-n177686-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Apartments in Chula Vista](https://www.expedia.ca/Chula-Vista-Apartments.d7442-aaApartments.Travel-Guide-Accommodation) - [Cabin Rentals in Chula Vista](https://www.expedia.ca/Chula-Vista-Cabins.d7442-aaCabins.Travel-Guide-Accommodation) - [Hotels near Chula Vista Center](https://www.expedia.ca/Chula-Vista-Center-Hotels.0-l553248621560505608-0.Travel-Guide-Filter-Hotels) - 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