Title: South San Diego Guest Houses from CA $129 | Expedia.ca [South San Diego Travel Guide](https://expedia.ca/South-San-Diego.dx553248632063518562)[Hotels in South San Diego](https://expedia.ca/South-San-Diego-Hotels.d553248632063518562.Travel-Guide-Hotels)[Vacation Rentals in South San Diego](https://expedia.ca/South-San-Diego-Vacation-Rentals.d553248632063518562.Travel-Guide-VacationRentals)[Flights to South San Diego](https://expedia.ca/Cheap-Flights-To-South-San-Diego.d553248632063518562.Travel-Guide-Flights)[Things to do in South San Diego](https://expedia.ca/Things-To-Do-In-South-San-Diego.d553248632063518562.Travel-Guide-Activities)[South San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-South-San-Diego.d553248632063518562.Car-Rental-Guide)[South San Diego Vacation Packages](https://expedia.ca/South-San-Diego.d553248632063518562.Destination-Travel-Guides) ![SanDiego_MattressFirmAmphitheatre_6128061_005](https://images.trvl-media.com/place/6128061/636e1116-2897-4eb1-8571-9a903b01ec2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Guest Houses in South San Diego from CA $129 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2026-01-09&endDate=2026-01-11&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2026-01-16&endDate=2026-01-18&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2026-01-30&endDate=2026-02-01&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2026-02-27&endDate=2026-03-01&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South San Diego guest houses ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/40601c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/1dcb5057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/06ca5233.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/c4b4e77a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Primero Hotel [](https://www.expedia.ca/Chula-Vista-Hotels-El-Primero-Hotel.h1630286.Hotel-Information) Downtown Chula Vista 9.2/10 Wonderful (1001) "The owner was very hospitable. My room was so clean and tidy." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jiabao CA $117 CA $129 total includes taxes & fees Jan 6 - Jan 7 [](https://www.expedia.ca/Chula-Vista-Hotels-El-Primero-Hotel.h1630286.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/da8f2406.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed (Wedgewood) | Living area](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/6988f242.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/6d6bdbe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/f6cdb0c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vineyard Hacienda [](https://www.expedia.ca/Spring-Valley-Hotels-Vineyard-Hacienda.h8782409.Hotel-Information) Spring Valley 9.2/10 Wonderful (542) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christophe CA $213 CA $231 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Spring-Valley-Hotels-Vineyard-Hacienda.h8782409.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99780000/99776200/99776102/995104d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/100000000/99780000/99776200/99776102/efc2a8fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/100000000/99780000/99776200/99776102/622d2be2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/100000000/99780000/99776200/99776102/8b478f21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stylish North Park Bungalow|Patio+Private Parking [](https://www.expedia.ca/San-Diego-Hotels-Stylish.h99776102.Hotel-Information) North Park 10/10 Exceptional (7) "It's close to everything. Very clean. And the property manager is there to fix any problems you may come across. Overall a wonderful little place to be. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emili F. CA $149 CA $454 total includes taxes & fees Jan 5 - Jan 6 [](https://www.expedia.ca/San-Diego-Hotels-Stylish.h99776102.Hotel-Information) ![Fridge, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/158cade6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/6043b3cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/075d2a58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/08361f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heart of SD | Zoo Nearby | Private Patio | Central [](https://www.expedia.ca/San-Diego-Hotels-Modern-Gem-Private-Patio-Central-Heart-Of-SD.h100222473.Hotel-Information) Mid-City 8.0/10 Very good (4) "Such a cute and perfect spot! Had all the thoughtful touches. Was very cozy, bed was comfy and little patio was great. I would definitely stay here again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tanya R. CA $104 CA $254 total includes taxes & fees Jan 5 - Jan 6 [](https://www.expedia.ca/San-Diego-Hotels-Modern-Gem-Private-Patio-Central-Heart-Of-SD.h100222473.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/98000000/97070000/97066900/97066837/af55d26f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/98000000/97070000/97066900/97066837/36be6976.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/98000000/97070000/97066900/97066837/5d6eb8d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/98000000/97070000/97066900/97066837/d78a202f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Designer Poolside La Mesa Retreat w/ BBQ & Yard [](https://www.expedia.ca/La-Mesa-Hotels-Designer-Poolside-1Bed1Bth-Retreat.h97066837.Hotel-Information) La Mesa 8.8/10 Excellent (6) "Nice private property. Loved sitting by the pool. Very convenient to get around the area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Jo F. CA $188 CA $495 total includes taxes & fees Jan 5 - Jan 6 [](https://www.expedia.ca/La-Mesa-Hotels-Designer-Poolside-1Bed1Bth-Retreat.h97066837.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/d4d636ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/edab4306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/eb794f40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/0d3d76b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Garden Cottage | 200Mbps | Sofabed | 55”TV | Patio [](https://www.expedia.ca/San-Diego-Hotels-Garden-Cottage-200Mbps-Sofabed-55TV-Patio.h118128543.Hotel-Information) University City 10/10 Exceptional (1) "Great place,near my son so was perfect" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) noel o. CA $169 CA $456 total includes taxes & fees Jan 5 - Jan 6 [](https://www.expedia.ca/San-Diego-Hotels-Garden-Cottage-200Mbps-Sofabed-55TV-Patio.h118128543.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/198e6a6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/89729cf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, books, streaming services](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/ab7e7ec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/3706623f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rockaway North - Family Friendly, Garage Parking & Laundry [](https://www.expedia.ca/San-Diego-Hotels-Rockaway-North-Family-Friendly.h92449548.Hotel-Information) Mission Beach 9.8/10 Exceptional (26) "A wonderful spot for our quick beach get-a-way! The property was stocked with everything we needed ... super clean and close to the market and lots of great eateries. It definitely was a plus to have access to beach chairs, umbrella and towels, and it's just steps to the beach. We look forward to our next stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raeann Z. CA $242 CA $550 total includes taxes & fees Jan 31 - Feb 1 [](https://www.expedia.ca/San-Diego-Hotels-Rockaway-North-Family-Friendly.h92449548.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/5afb3714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/3f8053a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/514bc114.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/a8221a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Newly Built Guest Home [](https://www.expedia.ca/San-Diego-Hotels-Newly-Built-Guest-Home.h91135120.Hotel-Information) Mira Mesa 10/10 Exceptional (36) "I would highly recommended to stay this property. It’s super close to everything! Brian super responsive to everything you need during your stays. It’s perfect for our family! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberta C. CA $410 CA $779 total includes taxes & fees Jan 5 - Jan 6 [](https://www.expedia.ca/San-Diego-Hotels-Newly-Built-Guest-Home.h91135120.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-18&endDate=2026-01-19®ionId=553248632063518562&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-San-Diego-Guest-Houses.d553248632063518562-aaGuestHouses.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-San-Diego-Guest-Houses.d553248632063518562-aaGuestHouses.Travel-Guide-Accommodation) ## Top South San Diego Hotel Reviews ![Marriott Marquis San Diego Marina](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/9078a9ee_y.jpg) ### Marriott Marquis San Diego Marina 10/10 Excellent "Great service " [](https://expedia.ca/San-Diego-Hotels-Marriott-Marquis-San-Diego-Marina.h24394.Hotel-Information) ![Sentral Gaslamp Quarter](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/b82a5191_y.jpg) ### Sentral Gaslamp Quarter 10/10 Excellent "Clean and friendly staff" [](https://expedia.ca/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "Yes " [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "Great " [](https://expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Resort.h11109.Hotel-Information) ![Hilton San Diego Mission Valley](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/w5586h3835x5y5-2b129a15_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Very courteous lady at the front counter. Great beds. " [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Was perfect " [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg) ### Best Western Seven Seas 10/10 Excellent "Room was good and staff was very friendly and helpful." [](https://expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "Good " [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Hampton Inn San Diego/Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg) ### Hampton Inn San Diego/Mission Valley 10/10 Excellent "Work place, meetin place, seimming pool, convenience shop, delicious and high quality breakfasts, Keeping all places very neat and clean. " [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ## Find out more about South San Diego ## South San Diego Guest Houses information | Number of reviews | 1,550 | | ----------------- | --------------- | | Accommodation | 15 Guest Houses | | Lowest Price | CA $129 | | Highest Price | CA $779 | ## Frequently asked questions ### What is the nightly rate for a guest house in South San Diego? ### What's the difference between a South San Diego guest house and a B&B? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Hotels near Beyer Blvd Trolley Station ](https://www.expedia.ca/Beyer-Blvd-Trolley-Station-Hotels.d6186828.Travel-Guide-Hotels) - [Camino Real Hotels in Castle Park ](https://www.expedia.ca/Castle-Park-Chula-Vista-Hotels-Camino-Real.0-n177686-0--bCaminoReal.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Castle Park ](https://www.expedia.ca/Castle-Park-Chula-Vista-Hotels-Couples-Resorts-Hotels.0-n177686-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - 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