Title: Book the Best BUSINESS Hotels in South of Market in 2026 | Expedia.ca [South of Market Travel Guide](https://expedia.ca/San-Francisco-South-Of-Market.dx160166)[Vacation Rentals in San Francisco](https://expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[South of Market Car Rentals](https://expedia.ca/Car-Rentals-In-South-Of-Market.d160166.Car-Rental-Guide)[South of Market Vacations](https://expedia.ca/South-Of-Market.d160166.Destination-Travel-Guides) ![South of Market showing skyline, a city and city views](https://images.trvl-media.com/place/160166/f4a16719-d8ac-4494-aeaa-4bbf3b1bebfc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/160166/f4a16719-d8ac-4494-aeaa-4bbf3b1bebfc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South of Market Business Hotels Tonight [Jan 29 - Jan 30](https://www.expedia.ca/Hotel-Search?regionId=160166&startDate=2026-01-29&endDate=2026-01-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Jan 30 - Jan 31](https://www.expedia.ca/Hotel-Search?regionId=160166&startDate=2026-01-30&endDate=2026-01-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=160166&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=160166&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for South of Market business-friendly hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/500/491/c9a2355d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Club Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/500/491/9b875e1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast served](https://images.trvl-media.com/lodging/1000000/10000/500/491/b103963b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 Bedroom | Living area](https://images.trvl-media.com/lodging/1000000/10000/500/491/14a438d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency San Francisco Downtown SOMA [](https://www.expedia.ca/San-Francisco-Hotels-The-Park-Central-San-Francisco-Hyatt-Affiliated-Hotel.h491.Hotel-Information) Downtown San Francisco 9.4/10 Exceptional (1,296 reviews) "Amazing, I would stay here again and recommend to family and friends. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tarandeep CA $213 CA $304 total includes taxes & fees Feb 20 - Feb 21 [](https://www.expedia.ca/San-Francisco-Hotels-The-Park-Central-San-Francisco-Hyatt-Affiliated-Hotel.h491.Hotel-Information) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/10000/8800/8737/ae4f08a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/10000/8800/8737/b19064bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8800/8737/6ae4adf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8800/8737/153e8bb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Francisco Marriott Marquis [](https://www.expedia.ca/San-Francisco-Hotels-San-Francisco-Marriott-Marquis.h8737.Hotel-Information) Downtown San Francisco 8.8/10 Excellent (1,242 reviews) "Convenient location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paolo CA $283 CA $381 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/San-Francisco-Hotels-San-Francisco-Marriott-Marquis.h8737.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11800/11793/d655bded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/20000/11800/11793/3f88e907.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/20000/11800/11793/289a909a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/11800/11793/0e7fe7cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Pickwick Hotel [](https://www.expedia.ca/San-Francisco-Hotels-The-Pickwick-Hotel.h11793.Hotel-Information) Downtown San Francisco 7.8/10 Good (1,102 reviews) "Fantastic Service! Loved my stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly CA $134 CA $158 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/San-Francisco-Hotels-The-Pickwick-Hotel.h11793.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/7fe7eb3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV, pay movies, MP3 dock](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/0c9770db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/f11ecdc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV, pay movies, MP3 dock](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/398a6ca9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-W-San-Francisco.h287112.Hotel-Information) Downtown San Francisco 9.0/10 Wonderful (1,002 reviews) "The check-in staff and location and were excellent! Great Wi-Fi reception and the location and ambience was the best. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randolph CA $237 CA $327 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/San-Francisco-Hotels-W-San-Francisco.h287112.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/5800bbe5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/7856c00e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/f7c5f6c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/5517eff5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental San Francisco by IHG [](https://www.expedia.ca/San-Francisco-Hotels-InterContinental-San-Francisco.h1766605.Hotel-Information) Downtown San Francisco 9.2/10 Wonderful (1,085 reviews) "Very nice hotel, great amenities and excelente service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica CA $241 CA $339 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/San-Francisco-Hotels-InterContinental-San-Francisco.h1766605.Hotel-Information) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/1000000/230000/225900/225819/b5cc10dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed, City View, Corner](https://images.trvl-media.com/lodging/1000000/230000/225900/225819/94c0b9bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/230000/225900/225819/84c87d37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/230000/225900/225819/de5c5a74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zelos San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zelos-San-Francisco.h225819.Hotel-Information) Downtown San Francisco 9.0/10 Wonderful (1,130 reviews) "Friendly staff, clean room, unbeliveably quiet interior courtyard. Nice bar and easy to get to our show. Would stay again. Valet parking was conveniant too!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tatiana CA $214 CA $308 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zelos-San-Francisco.h225819.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/004f15cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/e4464a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/e96af726.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Park View](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/3c515aa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel VIA [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-VIA.h16819669.Hotel-Information) Downtown San Francisco 9.2/10 Wonderful (1,512 reviews) "Great location and staff! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monica CA $255 CA $300 total includes taxes & fees Jan 31 - Feb 1 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-VIA.h16819669.Hotel-Information) ![Serves dinner and happy hour](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/69c56718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/1656ff5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/100ffc4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/e282d47e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Clancy, Autograph Collection by Marriott [](https://www.expedia.ca/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information) Downtown San Francisco 9.2/10 Wonderful (1,001 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey CA $235 CA $333 total includes taxes & fees Feb 20 - Feb 21 [](https://www.expedia.ca/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/w4000h2663x0y0-df4f3756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/189643db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/ad005a29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/e72fe89a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palace Hotel, a Luxury Collection Hotel, San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-Palace-Hotel.h27274.Hotel-Information) Downtown San Francisco 9.2/10 Wonderful (1,000 reviews) "Stand outs: the staff, the pool, the polar bear Christmas decorations, and close to restaurants. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet CA $413 CA $486 total includes taxes & fees Feb 20 - Feb 21 [](https://www.expedia.ca/San-Francisco-Hotels-Palace-Hotel.h27274.Hotel-Information) ![Suite (Skyline Waterfront Penthouse) | View from room](https://images.trvl-media.com/lodging/1000000/10000/400/384/1b7910ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/1000000/10000/400/384/a04417ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/400/384/6dda3257.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/1000000/10000/400/384/df9b3b05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harbor Court Hotel [](https://www.expedia.ca/San-Francisco-Hotels-Harbor-Court-Hotel.h384.Hotel-Information) Downtown San Francisco 9.0/10 Wonderful (1,001 reviews) "Beautifully remodeled, convenient, great staff. Room was nicely furnished and comfortable bed. Would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Analea CA $196 CA $295 total includes taxes & fees Jan 31 - Feb 1 [](https://www.expedia.ca/San-Francisco-Hotels-Harbor-Court-Hotel.h384.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-12&endDate=2026-02-13®ionId=160166&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top South of Market Hotel Reviews ![Holiday Inn Golden Gateway by IHG](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f_y.jpg) ### Holiday Inn Golden Gateway by IHG 10/10 Excellent "Very clean and comfy " [](https://expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information) ![Hotel Zelos San Francisco](https://images.trvl-media.com/lodging/1000000/230000/225900/225819/b5cc10dd_y.jpg) ### Hotel Zelos San Francisco 10/10 Excellent "Very impressive hotel in all ways - great location, friendly and accommodating staff, comfortable and spacious room, and a wonderful restaurant/bar hidden away on the fifth or sixth floor of the hotel." [](https://expedia.ca/San-Francisco-Hotels-Hotel-Zelos-San-Francisco.h225819.Hotel-Information) ![Hotel Riu Plaza Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg) ### Hotel Riu Plaza Fisherman's Wharf 10/10 Excellent "Everything was fantastic from check-in the beauty of the hotel the cleanliness the ease of parking friendlyness of the staff the room was made up perfectly truly enjoyed the great breakfast five stars. " [](https://expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![InterContinental San Francisco by IHG](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/5800bbe5_y.jpg) ### InterContinental San Francisco by IHG 10/10 Excellent "Very nice hotel, great amenities and excelente service " [](https://expedia.ca/San-Francisco-Hotels-InterContinental-San-Francisco.h1766605.Hotel-Information) ![Hotel VIA](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/ce95cac7_y.jpg) ### Hotel VIA 10/10 Excellent "A great stay! went here for a concert wanted to stay overnight and drink with my husband " [](https://expedia.ca/San-Francisco-Hotels-Hotel-VIA.h16819669.Hotel-Information) ![San Francisco Marriott Marquis](https://images.trvl-media.com/lodging/1000000/10000/8800/8737/71913965_y.jpg) ### San Francisco Marriott Marquis 10/10 Excellent "Excellent " [](https://expedia.ca/San-Francisco-Hotels-San-Francisco-Marriott-Marquis.h8737.Hotel-Information) ![The Pickwick Hotel](https://images.trvl-media.com/lodging/1000000/20000/11800/11793/060ec935_y.jpg) ### The Pickwick Hotel 10/10 Excellent "Fantastic Service! Loved my stay!" [](https://expedia.ca/San-Francisco-Hotels-The-Pickwick-Hotel.h11793.Hotel-Information) ![Palace Hotel, a Luxury Collection Hotel, San Francisco](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/w4000h2663x0y0-df4f3756_y.jpg) ### Palace Hotel, a Luxury Collection Hotel, San Francisco 10/10 Excellent "The bidet is the real winner! Overall, it's a good stay. " [](https://expedia.ca/San-Francisco-Hotels-Palace-Hotel.h27274.Hotel-Information) ![The Mosser](https://images.trvl-media.com/lodging/1000000/560000/553900/553859/e6dd0408_y.jpg) ### The Mosser 10/10 Excellent "Great staff and clean" [](https://expedia.ca/San-Francisco-Hotels-The-Mosser.h553859.Hotel-Information) ## Frequently asked questions ### Why book your business-friendly hotel in South of Market with Expedia? ### How can I find cheap business-friendly hotels in South of Market? ## Explore a world of travel with Expedia - Lodging - More ways to book - [Cheap Hotels in San Francisco County ](https://www.expedia.ca/Destinations-In-San-Francisco-County-Cheap-Hotels.0-0-d553248635996709347-tCheapHotels.Hotel-Filter-Destinations) - [Hotels with a Pool in San Francisco County ](https://www.expedia.ca/Destinations-In-San-Francisco-County-Hotel-With-Pool.0-0-d553248635996709347-tHotelwithPool.Hotel-Filter-Destinations) - [Luxury Hotels in San Francisco County ](https://www.expedia.ca/Destinations-In-San-Francisco-County-Luxury-Hotel.0-0-d553248635996709347-tLuxuryHotel.Hotel-Filter-Destinations) - 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