Title: Hotels by Wyndham Hotels in South Main from CA $77 | Expedia.ca [South Main Travel Guide](https://expedia.ca/Houston-South-Main.dx553248635976386992)[Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[South Main Car Rentals](https://expedia.ca/Car-Rentals-In-South-Main.d553248635976386992.Car-Rental-Guide)[South Main Vacations](https://expedia.ca/South-Main.d553248635976386992.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/7fff8623dc31b090fdc6a6747a27a07c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Hazem Abdul # Find Hotels by Wyndham Hotels in South Main from CA $77 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 19 - Oct 20](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-10-19&endDate=2025-10-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 20 - Oct 21](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-10-20&endDate=2025-10-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South Main Wyndham Hotels Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/64200/64160/d042d154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/64200/64160/57c287ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/64200/64160/c00587af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/70000/64200/64160/caf434d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham Sugar Land 8.8/10 Excellent (1026) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bernardo CA $118 CA $136 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Houston-Hotels-Heritage-Inn-Suites-HoustonSugar-Land.h64160.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/w2558h1440x0y0-44773629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/83265e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/63833027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pet-friendly](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/982edefb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Houston near NRG Park/Medical Center South Main 7.2/10 Good (1180) "Everyone was very pleasant, I will be returning." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy CA $139 CA $162 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) ![Pillowtop beds, individually decorated, individually furnished](https://images.trvl-media.com/lodging/41000000/40190000/40186600/40186592/5d4fd018.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, Multiple Beds](https://images.trvl-media.com/lodging/41000000/40190000/40186600/40186592/a2a168ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment, 1 King Bed, Corner (Corner Suite)](https://images.trvl-media.com/lodging/41000000/40190000/40186600/40186592/54edcc18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 King Bed (Studio) | Living area](https://images.trvl-media.com/lodging/41000000/40190000/40186600/40186592/99ee962a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reside Houston Dwntwn, Wyndham Downtown Houston 8.6/10 Excellent (822) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel CA $177 CA $207 total includes taxes & fees Nov 20 - Nov 21 [](https://www.expedia.ca/Houston-Hotels-Sonder-The-Hogg-Palace.h40186592.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27700/27662/f7140d86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27700/27662/bf94d0be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/27700/27662/6ae178c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/27700/27662/8a2cc3ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Houston Hobby Airport Southeast Houston 6.8/10 (955) "Convenient to airport" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Krystle CA $66 CA $77 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Houston-Hotels-Holiday-Inn-Houston-Hobby-Airport.h27662.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6400/6399/c0c41356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6400/6399/8e1b1cb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/6400/6399/2680d25b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6400/6399/a57dbff1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Houston Sugarland Alief 3.2/10 (7) "The pictures are AI generated pictures, it doesn't look like 1% of what is shown in the picture, As per attendant the hotel is going under renovations, the key card was not working and someone has to assist us with the KEY to open and close the door whenever we comes and leave, not to mention the whole hotel smells like Indian food. The exterior is all messed up, even the name is gone, parking lot is not safe as well. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nohail CA $88 CA $103 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Sugarland.h6399.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-03&endDate=2025-11-04®ionId=553248635976386992&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Main-Houston-Hotels-Wyndham-Hotels.0-n553248635976386992-0--bWyndhamHotels.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Main-Houston-Hotels-Wyndham-Hotels.0-n553248635976386992-0--bWyndhamHotels.Travel-Guide-Filter-Hotels) ## Top South Main Hotel Reviews ![Club Quarters Hotel Downtown, Houston](//images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd_y.jpg) ### Club Quarters Hotel Downtown, Houston 10/10 Excellent "Stay was great, check in was very easy and it was in a great location " [](https://expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![Crowne Plaza Houston Med Ctr-Galleria Area by IHG](//images.trvl-media.com/lodging/1000000/30000/28100/28060/38218191_y.jpg) ### Crowne Plaza Houston Med Ctr-Galleria Area by IHG 10/10 Excellent "I didn’t eat breakfast." [](https://expedia.ca/Houston-Hotels-Crowne-Plaza-Houston-River-Oaks.h28060.Hotel-Information) ![Hilton Houston Plaza/Medical Center](//images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50_y.jpg) ### Hilton Houston Plaza/Medical Center 10/10 Excellent "This hotel was comfortable and reasonably priced for the area. I’d stay here again. " [](https://expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![Magnolia Hotel Houston, A Tribute Portfolio Hotel](//images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37_y.jpg) ### Magnolia Hotel Houston, A Tribute Portfolio Hotel 10/10 Excellent "We had a perfect time for our parents weekend visiting our son at college! " [](https://expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Houston Bush IAH South](//images.trvl-media.com/lodging/1000000/170000/165600/165562/0afb5a51_y.jpg) ### La Quinta Inn & Suites by Wyndham Houston Bush IAH South 10/10 Excellent "i tried numerous times to arrange a shuttle from IAH to the hotel... but no one ever answered the front desk number that was provided. In frustration i booked a cab. As i checked in i made sure that i would be on the 8am shuttle rhe following morning. The following morning i went to wait for the airport shuttle and was told my name wasn't on the list. Thankfully an uber was available to take me to mt flight. Not happy!!" [](https://expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-Bush-IAH-South.h165562.Hotel-Information) ![Hotel Zaza Houston Museum District](//images.trvl-media.com/lodging/1000000/10000/3400/3306/47c5ade4_y.jpg) ### Hotel Zaza Houston Museum District 10/10 Excellent "Nice room- thought it would be fancier. The bathrooms were really nice! When we got back from out event there was a charcuterie board waiting for us. Loved that suprise!!" [](https://expedia.ca/Houston-Hotels-Hotel-Zaza-Houston-Museum-District.h3306.Hotel-Information) ![DoubleTree by Hilton Hotel Houston - Greenway Plaza](//images.trvl-media.com/lodging/1000000/30000/20200/20177/682ca680_y.jpg) ### DoubleTree by Hilton Hotel Houston - Greenway Plaza 10/10 Excellent "VERY GOOD PLACE TO STAY." [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Houston-Greenway-Plaza.h20177.Hotel-Information) ![DoubleTree by Hilton Hotel & Suites Houston by the Galleria](//images.trvl-media.com/lodging/1000000/30000/20200/20116/555244ce_y.jpg) ### DoubleTree by Hilton Hotel & Suites Houston by the Galleria 10/10 Excellent "Nice stay" [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Suites-Houston-By-The-Galleria.h20116.Hotel-Information) ![The Whitehall Houston](//images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056_y.jpg) ### The Whitehall Houston 10/10 Excellent "Good" [](https://expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information) ## Find out more about South Main ## South Main Hotels Guide Expedia.ca offers a selection of 6554 hotels in South Main. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in South Main. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the South Main neighborhood you prefer. Go ahead. 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