Title: Hotels by Hilton Hotels in South Main from CA $170 | Expedia.ca [South Main Travel Guide](https://expedia.ca/Houston-South-Main.dx553248635976386992)[Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[South Main Car Rentals](https://expedia.ca/Car-Rentals-In-South-Main.d553248635976386992.Car-Rental-Guide)[South Main Vacations](https://expedia.ca/South-Main.d553248635976386992.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/7fff8623dc31b090fdc6a6747a27a07c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Hazem Abdul # Find Hotels by Hilton Hotels in South Main from CA $170 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 21 - Oct 22](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-10-21&endDate=2025-10-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 22 - Oct 23](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-10-22&endDate=2025-10-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South Main Hilton Hotels Hotels ![Sundeck](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/8964faa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/12af8c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/f8ddb5e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston Plaza/Medical Center Texas Medical Center 8.4/10 Very good (1651) "Amazing stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JeVandon CA $160 CA $189 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![Serves dinner and happy hour](https://images.trvl-media.com/lodging/1000000/10000/900/809/72a26fde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/900/809/3a715a2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/809/6672412d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/10000/900/809/7dd4c532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston North Northside 8.2/10 Very good (1012) "I enjoyed my stay, the housekeeping are very nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adama CA $146 CA $170 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-North.h809.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/79245093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/w3840h2558x0y0-562426d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/8cd20a4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Americas-Houston Downtown Houston 9.4/10 Exceptional (1534) "Very pleasant staff. Lovely stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon CA $229 CA $271 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25600/25502/07704909.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/25600/25502/40af4923.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/25600/25502/4b8c552d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/30000/25600/25502/2cbe4962.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston Post Oak by the Galleria The Galleria 8.2/10 Very good (1013) "Excellent hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hassan CA $206 CA $241 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Post-Oak-By-The-Galleria.h25502.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/19000000/18990000/18989200/18989138/dab05571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/19000000/18990000/18989200/18989138/73e6e121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/19000000/18990000/18989200/18989138/6fe2f729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/19000000/18990000/18989200/18989138/w3839h2500x0y56-386e2fdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston Westchase Westchase 7.8/10 Good (1004) "Beautiful hotel. Extremely friendly staff. The hotel is in a great location with a variety of dining options." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gaynel CA $148 CA $174 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Westchase.h18989138.Hotel-Information) ![1 bedroom, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/1000000/50000/40800/40758/6849951e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/1000000/50000/40800/40758/310d4c81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/50000/40800/40758/d0cccaac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40758/6b848d1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton University of Houston Southeast Houston 8.8/10 Excellent (874) "Nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexandra CA $217 CA $254 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Houston-Hotels-Hilton-University-Of-Houston.h40758.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-04&endDate=2025-11-05®ionId=553248635976386992&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Main-Houston-Hotels-Hilton-Hotels.0-n553248635976386992-0--bHiltonHotels.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Main-Houston-Hotels-Hilton-Hotels.0-n553248635976386992-0--bHiltonHotels.Travel-Guide-Filter-Hotels) ## Top South Main Hotel Reviews ![Hyatt Place Houston/Galleria](//images.trvl-media.com/lodging/13000000/12300000/12294900/12294828/36442d5d_y.jpg) ### Hyatt Place Houston/Galleria 10/10 Excellent "Wed" [](https://expedia.ca/Houston-Hotels-Hyatt-Place-HoustonGalleria.h12294828.Hotel-Information) ![Club Quarters Hotel Downtown, Houston](//images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd_y.jpg) ### Club Quarters Hotel Downtown, Houston 10/10 Excellent "Excelente " [](https://expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![The Royal Sonesta Houston Galleria](//images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960_y.jpg) ### The Royal Sonesta Houston Galleria 10/10 Excellent "The staff was really caring and welcoming. We enjoyed our stay! " [](https://expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) ![DoubleTree by Hilton Hotel & Suites Houston by the Galleria](//images.trvl-media.com/lodging/1000000/30000/20200/20116/555244ce_y.jpg) ### DoubleTree by Hilton Hotel & Suites Houston by the Galleria 10/10 Excellent "All the staff was nice and helpful" [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Suites-Houston-By-The-Galleria.h20116.Hotel-Information) ![The Whitehall Houston](//images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056_y.jpg) ### The Whitehall Houston 10/10 Excellent "The hotel staff are all excellent! Very friendly and so welcoming. The hotel restaurant serves a delicious breakfast with great choices. The gym is small but had the basics and got the job done just fine. The room was very spacious but the split bathroom layout was a little odd" [](https://expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information) ![Crowne Plaza Houston Med Ctr-Galleria Area by IHG](//images.trvl-media.com/lodging/1000000/30000/28100/28060/38218191_y.jpg) ### Crowne Plaza Houston Med Ctr-Galleria Area by IHG 10/10 Excellent "I didn’t eat breakfast." [](https://expedia.ca/Houston-Hotels-Crowne-Plaza-Houston-River-Oaks.h28060.Hotel-Information) ![Hilton Houston Plaza/Medical Center](//images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50_y.jpg) ### Hilton Houston Plaza/Medical Center 10/10 Excellent "This hotel was comfortable and reasonably priced for the area. I’d stay here again. " [](https://expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![Magnolia Hotel Houston, A Tribute Portfolio Hotel](//images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37_y.jpg) ### Magnolia Hotel Houston, A Tribute Portfolio Hotel 10/10 Excellent "We had a perfect time for our parents weekend visiting our son at college! " [](https://expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Houston Bush IAH South](//images.trvl-media.com/lodging/1000000/170000/165600/165562/0afb5a51_y.jpg) ### La Quinta Inn & Suites by Wyndham Houston Bush IAH South 10/10 Excellent "i tried numerous times to arrange a shuttle from IAH to the hotel... but no one ever answered the front desk number that was provided. In frustration i booked a cab. As i checked in i made sure that i would be on the 8am shuttle rhe following morning. The following morning i went to wait for the airport shuttle and was told my name wasn't on the list. Thankfully an uber was available to take me to mt flight. Not happy!!" [](https://expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-Bush-IAH-South.h165562.Hotel-Information) ## Find out more about South Main ## South Main Hotels Guide Expedia.ca offers a selection of 6547 hotels in South Main. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in South Main. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the South Main neighborhood you prefer. Go ahead. 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