Title: Book the Best CHEAP Hotels in South Main, Houston from CA $121 - South Main Cheap Hotels | Expedia.ca [Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[South Main Car Rentals](https://expedia.ca/Car-Rentals-In-South-Main.d553248635976386992.Car-Rental-Guide)[South Main Vacations](https://expedia.ca/South-Main.d553248635976386992.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/7fff8623dc31b090fdc6a6747a27a07c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Hazem Abdul # Find Cheap Hotels in South Main, Houston from CA $121 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Main Cheap Hotels Tonight [Oct 13 - Oct 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-10-13&endDate=2025-10-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 14 - Oct 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-10-14&endDate=2025-10-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South Main Cheap Hotels ![Gazebo](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/ab4b9445.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/98547457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/6b2e094a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/bdf24163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wingate Houston near NRG Park/Medical Center South Main 6.6/10 (945) "Walking distance to NRG Stadium " CA $111 CA $129 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/w2558h1440x0y0-44773629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pet-friendly](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/982edefb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/63833027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 10:00 AM to 6:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/e04a9b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Houston near NRG Park/Medical Center South Main 7.2/10 Good (1179) "Everyone was very pleasant, I will be returning." CA $139 CA $162 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/168bdeac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/b0f701b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/27e929b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/13fb2418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Houston Medical Center by IHG South Main 7.4/10 Good (802) "The staff is great. The area is questionable due to homeless population." CA $104 CA $121 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855900/855816/9e6e12ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/855900/855816/f5552223.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/860000/855900/855816/e00529c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855900/855816/4db24b48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Hotel Houston Tx Medical Center Nrg Stadium South Main 3.8/10 (425) "Closed down " [](https://www.expedia.ca/Houston-Hotels-OYO-Hotel-Houston-Tx-Medical-Center-Nrg-Stadium.h855816.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-27&endDate=2025-10-28®ionId=553248635976386992&adults=2&travelerType=budget_property&sort=RECOMMENDED&openPlayBack=true) ## Top South Main Hotel Reviews ![Crowne Plaza Houston Med Ctr-Galleria Area by IHG](//images.trvl-media.com/lodging/1000000/30000/28100/28060/38218191_y.jpg) ### Crowne Plaza Houston Med Ctr-Galleria Area by IHG 10/10 Excellent "Breakfast was so so" [](https://expedia.ca/Houston-Hotels-Crowne-Plaza-Houston-River-Oaks.h28060.Hotel-Information) ![The Whitehall Houston](//images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056_y.jpg) ### The Whitehall Houston 10/10 Excellent "Only part I have something to say about is the valet workers they were rude " [](https://expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Houston Bush IAH South](//images.trvl-media.com/lodging/1000000/170000/165600/165562/0afb5a51_y.jpg) ### La Quinta Inn & Suites by Wyndham Houston Bush IAH South 10/10 Excellent "The room was clean, and the staff was friendly." [](https://expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-Bush-IAH-South.h165562.Hotel-Information) ![Club Quarters Hotel Downtown, Houston](//images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd_y.jpg) ### Club Quarters Hotel Downtown, Houston 10/10 Excellent "Loved my stay 5 stars" [](https://expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![Hilton Americas-Houston](//images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59_y.jpg) ### Hilton Americas-Houston 10/10 Excellent "Clean room, friendly staff, walkable to GRB, Discovery Green and Toyota Center " [](https://expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) ![Magnolia Hotel Houston, A Tribute Portfolio Hotel](//images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37_y.jpg) ### Magnolia Hotel Houston, A Tribute Portfolio Hotel 10/10 Excellent "Incredible value! Clean and tidy hotel with a great vibe, and the price can't be beat. Room was somewhat small, but the bathroom was spacious. Location was perfect - close to what we were doing on Texas St. in Downtown Houston. It was all we needed for a quick overnight in Houston! " [](https://expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) ![Hotel Zaza Houston Museum District](//images.trvl-media.com/lodging/1000000/10000/3400/3306/47c5ade4_y.jpg) ### Hotel Zaza Houston Museum District 10/10 Excellent "I was having some significant mental health issues…This was cheaper and more therapeutic. The staff was just reflexively nice and accommodating. Sometimes all you need is nice and well intentioned people around you, in any companies, to relax, to restores Thanks y’all ❤️" [](https://expedia.ca/Houston-Hotels-Hotel-Zaza-Houston-Museum-District.h3306.Hotel-Information) ![The Royal Sonesta Houston Galleria](//images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960_y.jpg) ### The Royal Sonesta Houston Galleria 10/10 Excellent "Close to highway, popular places. Clean facility and convenient." [](https://expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) ![Hilton Houston Plaza/Medical Center](//images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50_y.jpg) ### Hilton Houston Plaza/Medical Center 10/10 Excellent "Front desk staff were awesome " [](https://expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ## Frequently asked questions ### What is South Main like for travelers on a budget? > Check out discount places to stay in South Main on Expedia.com and book a getaway that matches your budget. You can scroll through a variety of accommodation choices with Member Prices to find great deals. With our site's helpful page filters, you can search by price per night, or by amenities that customers often look for like free breakfast and free WiFi. If you're interested in affordable options near specific attractions, such as NRG Park, try filtering by location to refine your search. As you browse, use the heart button to save your favorites so that you can return to them easily when you're ready to decide. Need a car or a flight too? Choose from the Bundle and Save vacation packages and discover big savings when you arrange your transportation at the same time. ### What is there to see and do in South Main? > You don't need to spend a lot to find places to visit in South Main. You can budget for the top local attractions on your list, such as NRG Stadium and Houston Zoo, and then make time for other wallet-friendly activities. Hunt for bargains with some shopping at Richmond Avenue and Highland Village, or get outdoors at Hermann Park. ### How can I get to South Main and get around on a budget? > Checking out these ways to get around South Main can help keep you on budget. The most convenient airport is 8.6 mi (13.8 km) from the center in Houston William Hobby Airport (HOU). If that doesn't suit your budget, you can look into flights to Houston, TX (EFD-Ellington Field), which is 15.6 mi (25.2 km) away. 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