Title: Book the Best BUSINESS Hotels in South Houston in 2026 | Expedia.ca [Hotels in South Houston](https://expedia.ca/South-Houston-Hotels.d160026.Travel-Guide-Hotels)[Vacation Rentals in South Houston](https://expedia.ca/South-Houston-Vacation-Rentals.d160026.Travel-Guide-VacationRentals)[South Houston Car Rentals](https://expedia.ca/Car-Rentals-In-South-Houston.d160026.Car-Rental-Guide)[South Houston Vacation Packages](https://expedia.ca/South-Houston.d160026.Destination-Travel-Guides) ![Houston, Texas, USA Downtown Skyline over the Highways](https://images.trvl-media.com/place/160026/1a9c43fc-f926-4dde-9b0a-4901c2bbbbdb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in South Houston, TX from CA $85 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Houston Business Hotels Tonight [Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=160026&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=160026&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=160026&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=160026&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for South Houston business-friendly hotels ![Interior](https://images.trvl-media.com/lodging/116000000/115560000/115550700/115550694/b50fb68f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115560000/115550700/115550694/w3840h2877x0y3-bf276e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/116000000/115560000/115550700/115550694/1c27d1d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/116000000/115560000/115550700/115550694/fc0f10cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Pearland/Houston Medical Center Hotel [](https://www.expedia.ca/Houston-Hotels-Best-Western-Plus-PearlandHouston-Medical-Center-Hotel.h115550694.Hotel-Information) Southeast Houston 9.4/10 Exceptional (57) "Very nice and clean staff was great!!! Will vist again if im in that area " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roderick CA $110 CA $129 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Houston-Hotels-Best-Western-Plus-PearlandHouston-Medical-Center-Hotel.h115550694.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/aa7fafd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/76e7278c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/c1fa2b90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Quarters Hotel Downtown, Houston [](https://www.expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) Downtown Houston 8.4/10 Very good (3941) "Rooms were great and the staff was absolutely amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elmer CA $104 CA $122 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![Exclusive Room, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1250000/1240800/1240788/dcc5346d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1250000/1240800/1240788/6c2cf751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1250000/1240800/1240788/557d86e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1250000/1240800/1240788/w800h584x0y0-b8e2ff5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Platinum Inn & Suites Webster [](https://www.expedia.ca/Houston-Hotels-Platinum-Inn-Suites-Webster.h1240788.Hotel-Information) Webster 7.8/10 Good (1001) "It was a great stay just perfect" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) elvin CA $72 CA $85 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Houston-Hotels-Platinum-Inn-Suites-Webster.h1240788.Hotel-Information) ![Pillowtop beds, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/35000000/34110000/34106600/34106566/05b12697.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/35000000/34110000/34106600/34106566/e7e548b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/35000000/34110000/34106600/34106566/4594e050.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/35000000/34110000/34106600/34106566/bf1b0361.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd [](https://www.expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-East-I-10.h34106566.Hotel-Information) Channelview 9.2/10 Wonderful (1002) "Very nice and clean Affordable and quiet " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda CA $96 CA $110 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-East-I-10.h34106566.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/908700/908672/bcc5356e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/908700/908672/50cb5749.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/910000/908700/908672/27503467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/908700/908672/5d091c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Suites Houston Hobby Airport [](https://www.expedia.ca/Houston-Hotels-Super-8-By-Wyndham-Houston-Hobby-Airport-North.h908672.Hotel-Information) Southeast Houston 8.4/10 Very good (1290) "Clean and spacious. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charlayne CA $82 CA $96 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Houston-Hotels-Super-8-By-Wyndham-Houston-Hobby-Airport-North.h908672.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/a403ab12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/2b2d8506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/81b3d19c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/88ce8c5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Houston Webster NASA [](https://www.expedia.ca/Houston-Hotels-Tru-By-Hilton-Houston-Webster-NASA.h27293821.Hotel-Information) Webster 9.0/10 Wonderful (1001) "The staff was super nice and the location worked great for us! " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Valeria CA $106 CA $124 total includes taxes & fees Jan 8 - Jan 9, 2026 [](https://www.expedia.ca/Houston-Hotels-Tru-By-Hilton-Houston-Webster-NASA.h27293821.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/72000000/71300000/71300000/71299937/0656f57f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/72000000/71300000/71300000/71299937/e6b0f6bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/72000000/71300000/71300000/71299937/7f9447a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room](https://images.trvl-media.com/lodging/72000000/71300000/71300000/71299937/7d0f0677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palace Inn Blue - Garth Rd [](https://www.expedia.ca/Houston-Hotels-Palace-Inn-Blue-Garth-Rd.h71299937.Hotel-Information) Baytown 9.0/10 Wonderful (259) "It was perfect for our family's movie weekend mini vacations.." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Orlando [](https://www.expedia.ca/Houston-Hotels-Palace-Inn-Blue-Garth-Rd.h71299937.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2950000/2947700/2947665/d3d99628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2950000/2947700/2947665/999ea0dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, individually decorated](https://images.trvl-media.com/lodging/3000000/2950000/2947700/2947665/515da46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2950000/2947700/2947665/7b2f6ee2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites - Houston Space Center by IHG [](https://www.expedia.ca/Houston-Hotels-Holiday-Inn-Express-Hotel-Suites-Houston-Space-Center.h2947665.Hotel-Information) Webster 9.0/10 Wonderful (1000) "Great staff and very clean hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew CA $110 CA $129 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Houston-Hotels-Holiday-Inn-Express-Hotel-Suites-Houston-Space-Center.h2947665.Hotel-Information) ![Sundeck](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/f2e085ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/8964faa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/f8ddb5e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston Plaza/Medical Center [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) Texas Medical Center 8.4/10 Very good (1757) "Loved the room, clean, friendly staff. Would reccomend :)" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rolando CA $116 CA $137 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/60000/50500/50482/8ff187b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50500/50482/d8b4e77f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/60000/50500/50482/b5b499d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/60000/50500/50482/82e8b572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Houston Baytown East [](https://www.expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-Baytown-East.h50482.Hotel-Information) Baytown 8.4/10 Very good (1003) "Nice place clean great parking" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris CA $82 CA $96 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-Baytown-East.h50482.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-02&endDate=2026-01-03®ionId=160026&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top South Houston Hotel Reviews ![DoubleTree by Hilton Hotel & Suites Houston by the Galleria](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/555244ce_y.jpg) ### DoubleTree by Hilton Hotel & Suites Houston by the Galleria 10/10 Excellent "Wonderful and the staff was awesome " [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Suites-Houston-By-The-Galleria.h20116.Hotel-Information) ![Hilton Americas-Houston](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59_y.jpg) ### Hilton Americas-Houston 10/10 Excellent "Beautiful amenities, excellent service and good staff" [](https://expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) ![Hotel Zaza Houston Museum District](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/47c5ade4_y.jpg) ### Hotel Zaza Houston Museum District 10/10 Excellent "I was not offered a free breakfast" [](https://expedia.ca/Houston-Hotels-Hotel-Zaza-Houston-Museum-District.h3306.Hotel-Information) ![Club Quarters Hotel Downtown, Houston](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd_y.jpg) ### Club Quarters Hotel Downtown, Houston 10/10 Excellent "Broken elevator was a slight frustration but overall, i liked the property." [](https://expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![Magnolia Hotel Houston, A Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37_y.jpg) ### Magnolia Hotel Houston, A Tribute Portfolio Hotel 10/10 Excellent "The hotel was beautifully decorated for Christmas. It was very clean and smelled nice. The valet service team was awesome! We had a queen double bed room. The room was appointed well and was spacious. The beds were comfortable, pillows were soft, the bathroom was roomy and I liked that the shower and toilet were separated from the bathroom sink space. We tried to use the hot tub but it was closed for maintenance. The gym was well equipped. The bar on the second floor was nice, and the staff made one of the best espresso martinis I've ever had. " [](https://expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) ![Holiday Inn Houston Downtown by IHG](https://images.trvl-media.com/lodging/9000000/8170000/8168200/8168134/f5ea3a06_y.jpg) ### Holiday Inn Houston Downtown by IHG 10/10 Excellent "The room was clean. I’m satisfied with the hair care and body lotion. It would be great if there were hair brush and more drink (soup) options." [](https://expedia.ca/Houston-Hotels-Holiday-Inn-Houston-Downtown.h8168134.Hotel-Information) ![The Westin Oaks Houston at the Galleria](https://images.trvl-media.com/lodging/1000000/10000/2800/2734/0b01ce73_y.jpg) ### The Westin Oaks Houston at the Galleria 10/10 Excellent "The room was large, beautifully decorated, comfortable mattress and pillows and very clean. We live in Houston and stayed at the Westin for a week while having work done in our house. The hotel was great and it was so nice to be connected to the Galleria for shopping and so many restaurants. The elevator system is very good and security is excellent. Self parking in the garage is free. The gym is nice and has 4 Pelotons." [](https://expedia.ca/Houston-Hotels-The-Westin-Oaks-Houston-At-The-Galleria.h2734.Hotel-Information) ![DoubleTree by Hilton Hotel Houston - Greenway Plaza](https://images.trvl-media.com/lodging/1000000/30000/20200/20177/682ca680_y.jpg) ### DoubleTree by Hilton Hotel Houston - Greenway Plaza 10/10 Excellent "Perfect " [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Houston-Greenway-Plaza.h20177.Hotel-Information) ![Omni Houston Hotel](https://images.trvl-media.com/lodging/1000000/20000/17800/17746/37423ee4_y.jpg) ### Omni Houston Hotel 10/10 Excellent "A great place to stay " [](https://expedia.ca/Houston-Hotels-Omni-Houston-Hotel.h17746.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in South Houston cost? ### What are the best business-friendly hotels in South Houston? ### How many business-friendly hotels are there in South Houston? ### What are the best cheap business-friendly hotels in South Houston? ### What are the top business-friendly motels in South Houston? ### Are there any family-friendly hotels in South Houston that are also business friendly? ### Why book your business-friendly hotel in South Houston with Expedia? ### How can I find cheap business-friendly hotels in South Houston? ### What is there to do in South Houston near my business-friendly hotel? ## Explore a world of travel with Expedia - 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