Title: Book the Best BUSINESS Hotels in South Central in 2025 | Expedia.ca [South Central Travel Guide](https://expedia.ca/Ann-Arbor-South-Central.dx896714409775411200)[Vacation Rentals in Ann Arbor](https://expedia.ca/Ann-Arbor-Vacation-Rentals.d6059241.Travel-Guide-VacationRentals)[Flights to Ann Arbor](https://expedia.ca/Cheap-Flights-To-Ann-Arbor.d6059241.Travel-Guide-Flights)[Things to do in Ann Arbor](https://expedia.ca/Things-To-Do-In-Ann-Arbor.d6059241.Travel-Guide-Activities)[South Central Car Rentals](https://expedia.ca/Car-Rentals-In-South-Central.d896714409775411200.Car-Rental-Guide)[South Central Vacations](https://expedia.ca/South-Central.d896714409775411200.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/9b3630010219c976a640056d02c7d377.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Carl Guttovz # Find Business Hotels in South Central, MI ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Central Business Hotels Tonight [Sep 29 - Sep 30](https://www.expedia.ca/Hotel-Search?regionId=896714409775411200&startDate=2025-09-29&endDate=2025-09-30&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 30 - Oct 1](https://www.expedia.ca/Hotel-Search?regionId=896714409775411200&startDate=2025-09-30&endDate=2025-10-01&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=896714409775411200&startDate=2025-10-03&endDate=2025-10-05&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=896714409775411200&startDate=2025-10-10&endDate=2025-10-12&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South Central Business Hotels ## Top South Central Hotel Reviews ![Comfort Inn & Suites University South](//images.trvl-media.com/lodging/1000000/920000/915500/915500/5c96e5f1_y.jpg) ### Comfort Inn & Suites University South 10/10 Excellent "Currently under renovation, looks nice what has been done so far." [](https://expedia.ca/Ann-Arbor-Hotels-Comfort-Inn-Suites-University-South.h915500.Hotel-Information) ![Saint John's Resort](//images.trvl-media.com/lodging/2000000/1340000/1330400/1330398/8343bf70_y.jpg) ### Saint John's Resort 10/10 Excellent "Beautiful property" [](https://expedia.ca/Detroit-Hotels-The-Inn-At-St-Johns.h1330398.Hotel-Information) ![Ann Arbor Regent Hotel & Suites](//images.trvl-media.com/lodging/1000000/20000/19000/18996/58e15b9b_y.jpg) ### Ann Arbor Regent Hotel & Suites 10/10 Excellent "On top of that the breakfast was amazing" [](https://expedia.ca/Ann-Arbor-Hotels-Ann-Arbor-Regent-Hotel-Suites.h18996.Hotel-Information) ![Wyndham Garden Ann Arbor](//images.trvl-media.com/lodging/1000000/460000/458100/458015/0abd6013_y.jpg) ### Wyndham Garden Ann Arbor 10/10 Excellent "Everything was great" [](https://expedia.ca/Ann-Arbor-Hotels-Wyndham-Garden-Ann-Arbor.h458015.Hotel-Information) ![Graduate by Hilton Ann Arbor](//images.trvl-media.com/lodging/1000000/30000/20200/20172/35526491_y.jpg) ### Graduate by Hilton Ann Arbor 10/10 Excellent "Lovely hotel a few block off the main drag in Ann Arbor and a 10-15 min walk from Kerrytown." [](https://expedia.ca/Ann-Arbor-Hotels-Graduate-Ann-Arbor.h20172.Hotel-Information) ![The Kensington Hotel](//images.trvl-media.com/lodging/1000000/10000/5800/5768/6ad931a7_y.jpg) ### The Kensington Hotel 10/10 Excellent "I stay here often and the staff is very friendly and accommodating every time. It would be nice to have updated rooms though. The decor is tired and old in many of the rooms I have stayed in but rooms are always clean. The Beekman products are really top notch. The restaurant staff were also very helpful and seated me where I could have my breakfast with my dog. I have stayed at other hotels in Ann Arbor and I still prefer to stay at the Kensington." [](https://expedia.ca/Ann-Arbor-Hotels-The-Kensington-Hotel.h5768.Hotel-Information) ![Weber's Hotel & Restaurant](//images.trvl-media.com/lodging/1000000/30000/21600/21561/ef32a41f_y.jpg) ### Weber's Hotel & Restaurant 10/10 Excellent "Comfortable. Helpful and friendly staff. " [](https://expedia.ca/Ann-Arbor-Hotels-Webers-Hotel-Restaurant.h21561.Hotel-Information) ![Fairfield Inn & Suites by Marriott Detroit Livonia](//images.trvl-media.com/lodging/1000000/290000/281100/281049/f240460c_y.jpg) ### Fairfield Inn & Suites by Marriott Detroit Livonia 10/10 Excellent "N/a" [](https://expedia.ca/Detroit-Hotels-Fairfield-Inn-Suites-By-Marriott-Detroit-Livonia.h281049.Hotel-Information) ![Larkspur Landing Ann Arbor](//images.trvl-media.com/lodging/1000000/30000/26100/26065/536d3c9f_y.jpg) ### Larkspur Landing Ann Arbor 10/10 Excellent "nice enough" [](https://expedia.ca/Ann-Arbor-Hotels-Larkspur-Landing-Ann-Arbor.h26065.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [5 Star Hotels in Ann Arbor](https://www.expedia.ca/5Star-Ann-Arbor-Hotels.s50-0-d6059241.Travel-Guide-Filter-Hotels) - [B&B in Ann Arbor](https://www.expedia.ca/Ann-Arbor-Bed-And-Breakfast.d6059241-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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[Flights from Ann Arbor](https://www.expedia.ca/lp/flights/6059241/flights-from-ann-arbor) - [Visit Allmendinger Heights](https://www.expedia.ca/Ann-Arbor-Allmendinger-Heights.dx553248635976472977) - [Visit Burns Park](https://www.expedia.ca/Ann-Arbor-Burns-Park.dx553248635976471400) - [Ann Arbor Vacations](https://www.expedia.ca/Ann-Arbor.d6059241.Destination-Travel-Guides) - [Visit Ann Arbor](https://www.expedia.ca/Ann-Arbor.dx6059241) - [Exhibit Museum of Natural History at the University Of Michigan](https://www.expedia.ca/Exhibit-Museum-Of-Natural-History-At-The-University-Of-Michigan-Central-Campus-Medical.d6074390.Vacation-Attraction) - [University of Michigan](https://www.expedia.ca/University-Of-Michigan-Bryant-Pattengill-West.d500955.Vacation-Attraction) - [Car rental Ann Arbor](https://www.expedia.ca/Car-Rentals-In-Ann-Arbor.d6059241.Car-Rental-Guide) - [Hertz Rental Cars in Ann Arbor](https://www.expedia.ca/Hertz-Car-Rentals-In-Ann-Arbor.d6059241-c40.Car-Rental-Guide-Suppliers) - 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