Title: Book the Best BUSINESS Hotels in South Central in 2025 | Expedia.ca [South Central Travel Guide](https://expedia.ca/Ann-Arbor-South-Central.dx896714409775411200)[Vacation Rentals in Ann Arbor](https://expedia.ca/Ann-Arbor-Vacation-Rentals.d6059241.Travel-Guide-VacationRentals)[Flights to Ann Arbor](https://expedia.ca/Cheap-Flights-To-Ann-Arbor.d6059241.Travel-Guide-Flights)[Things to do in Ann Arbor](https://expedia.ca/Things-To-Do-In-Ann-Arbor.d6059241.Travel-Guide-Activities)[South Central Car Rentals](https://expedia.ca/Car-Rentals-In-South-Central.d896714409775411200.Car-Rental-Guide)[South Central Vacations](https://expedia.ca/South-Central.d896714409775411200.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/9b3630010219c976a640056d02c7d377.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Carl Guttovz # Find Business Hotels in South Central, MI from CA $87 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Central Business Hotels Tonight [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=896714409775411200&startDate=2025-10-24&endDate=2025-10-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=896714409775411200&startDate=2025-10-25&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=896714409775411200&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=896714409775411200&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top South Central Business Hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/590000/581300/581221/1a31aebd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 Queen Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/590000/581300/581221/f7e03c80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/590000/581300/581221/8c597f24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/590000/581300/581221/9a8a44cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Ann Arbor Thurston 8.8/10 Excellent (1026) " Parking seemed safe and places to eat were in walking distance. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cheryl CA $114 CA $127 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Ann-Arbor-Hotels-Microtel-Inn-Suites-By-Wyndham-Ann-Arbor.h581221.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/580000/577500/577430/ab30e836.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/580000/577500/577430/d21b597a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/580000/577500/577430/adcf8749.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/580000/577500/577430/1a4cdff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Chelsea Chelsea 8.0/10 Very good (712) "Very clean room, very cordial staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tom CA $78 CA $87 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Jackson-Hotels-Comfort-Inn-Chelsea.h577430.Hotel-Information) ![Ballroom](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330398/8343bf70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330398/b9e4d7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330398/9aea63f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330398/cd16817e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Saint John's Resort Plymouth 9.6/10 Exceptional (1001) "Great location for fine dining, top notch rooms and excellent staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donald CA $196 CA $280 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Detroit-Hotels-The-Inn-At-St-Johns.h1330398.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1550000/1541100/1541083/83263dc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1550000/1541100/1541083/e630f744.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1550000/1541100/1541083/cb8e82ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1550000/1541100/1541083/420223cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn & Suites Ann Arbor Univ Michigan Area by IHG Bryant Pattengill East 8.0/10 Very good (976) "Great location for transportation and restaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenneth CA $114 CA $127 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Ann-Arbor-Hotels-Holiday-Inn-Suites-Ann-Arbor-Univ-Michigan-Area.h1541083.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/8300/8207/e8bd3a64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8300/8207/39a0a28b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8300/8207/224c2e94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/8300/8207/w4000h2665x0y2-867ca697.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn By Marriott Ann Arbor Bryant Pattengill East 8.4/10 Very good (1009) "Staff was great! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan CA $109 CA $121 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Ann-Arbor-Hotels-Fairfield-Inn-By-Marriott-Ann-Arbor.h8207.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9220000/9215400/9215322/1ab4adae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/10000000/9220000/9215400/9215322/65236de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds](https://images.trvl-media.com/lodging/10000000/9220000/9215400/9215322/6e499784.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9220000/9215400/9215322/1da52681.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Ann Arbor West by IHG Dexter 9.0/10 Wonderful (841) "Nice place, I would stay here again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brad CA $172 CA $191 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Ann-Arbor-Hotels-Holiday-Inn-Express-Suites-Ann-Arbor-West.h9215322.Hotel-Information) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/26100/26065/536d3c9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/26100/26065/5e750381.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26100/26065/abf02abf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/26100/26065/24c76310.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Larkspur Landing Ann Arbor Thurston 7.8/10 Good (1003) "Great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerome CA $105 CA $117 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Ann-Arbor-Hotels-Larkspur-Landing-Ann-Arbor.h26065.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327900/327826/dca17dc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327900/327826/ff8dd063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/1000000/330000/327900/327826/8cf5678b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, Non Smoking (1 Queen & 2 Bunk Beds)](https://images.trvl-media.com/lodging/1000000/330000/327900/327826/f7b81b84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Chelsea Chelsea 7.8/10 Good (1002) "Very friendly staff, comfortable beds and fee breakfast that has everything in minimal size " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Dani CA $87 CA $96 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Jackson-Hotels-Baymont-By-Wyndham-Chelsea.h327826.Hotel-Information) ![Suite, 1 King Bed | Private kitchenette](https://images.trvl-media.com/lodging/1000000/460000/458100/458015/0abd6013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/460000/458100/458015/cbc9a7cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/460000/458100/458015/89d2735b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/458100/458015/b8d4e003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Garden Ann Arbor Lakewood 7.2/10 Good (1297) "Great staff, very clean, comfy beds" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michaela CA $91 CA $101 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Ann-Arbor-Hotels-Wyndham-Garden-Ann-Arbor.h458015.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/130000/125500/125499/4f932e88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/125500/125499/8a4aa178.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/130000/125500/125499/39f4551d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/130000/125500/125499/cdb620cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Plymouth Plymouth 8.6/10 Excellent (920) "Stayed here to attend a wedding. I believe it was Niya at the front desk who was very helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marlon CA $139 CA $155 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Detroit-Hotels-Hilton-Garden-Inn-Plymouth.h125499.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-07&endDate=2025-11-08®ionId=896714409775411200&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top South Central Hotel Reviews ![Holiday Inn & Suites Ann Arbor Univ Michigan Area by IHG](//images.trvl-media.com/lodging/2000000/1550000/1541100/1541083/83263dc1_y.jpg) ### Holiday Inn & Suites Ann Arbor Univ Michigan Area by IHG 10/10 Excellent "Great location for transportation and restaurants." [](https://expedia.ca/Ann-Arbor-Hotels-Holiday-Inn-Suites-Ann-Arbor-Univ-Michigan-Area.h1541083.Hotel-Information) ![Saint John's Resort](//images.trvl-media.com/lodging/2000000/1340000/1330400/1330398/8343bf70_y.jpg) ### Saint John's Resort 10/10 Excellent "Nice area beautiful everything. I loved the prayer cards the most 🙏 ♥️ Staff was top notch, will be back!!!" [](https://expedia.ca/Detroit-Hotels-The-Inn-At-St-Johns.h1330398.Hotel-Information) ![Weber's Hotel & Restaurant](//images.trvl-media.com/lodging/1000000/30000/21600/21561/ef32a41f_y.jpg) ### Weber's Hotel & Restaurant 10/10 Excellent "The balcony overlooks the nice indoor pool area. The balcony deck is shared with neighbors which was a little weird. The pool requires adult supervision at all times unless your kids are 14+. No freezer in room, only a fridge. Otherwise well run hotel. " [](https://expedia.ca/Ann-Arbor-Hotels-Webers-Hotel-Restaurant.h21561.Hotel-Information) ![The Kensington Hotel](//images.trvl-media.com/lodging/1000000/10000/5800/5768/6ad931a7_y.jpg) ### The Kensington Hotel 10/10 Excellent "We could see the beautiful courtyard and the walk to it was not far at all. It such a serene " [](https://expedia.ca/Ann-Arbor-Hotels-The-Kensington-Hotel.h5768.Hotel-Information) ![Graduate by Hilton Ann Arbor](//images.trvl-media.com/lodging/1000000/30000/20200/20172/35526491_y.jpg) ### Graduate by Hilton Ann Arbor 10/10 Excellent "very clean and the beds very comfortable that’s all you need and love the decor is like Napoleon time " [](https://expedia.ca/Ann-Arbor-Hotels-Graduate-Ann-Arbor.h20172.Hotel-Information) ![Red Roof Inn Ann Arbor - U of Michigan South](//images.trvl-media.com/lodging/1000000/440000/439500/439427/fce511b1_y.jpg) ### Red Roof Inn Ann Arbor - U of Michigan South 10/10 Excellent "Clean fast check in no issues " [](https://expedia.ca/Ann-Arbor-Hotels-Red-Roof-Inn-Ann-Arbor-University-Of-Michigan-South.h439427.Hotel-Information) ![Wyndham Garden Ann Arbor](//images.trvl-media.com/lodging/1000000/460000/458100/458015/0abd6013_y.jpg) ### Wyndham Garden Ann Arbor 10/10 Excellent "The pool and hot tub were clean and temperatures were perfect! Breakfast was very fresh and hot (and we arrived at 10am). The staff that we did interact with was friendly and helpful." [](https://expedia.ca/Ann-Arbor-Hotels-Wyndham-Garden-Ann-Arbor.h458015.Hotel-Information) ![Ann Arbor Regent Hotel & Suites](//images.trvl-media.com/lodging/1000000/20000/19000/18996/58e15b9b_y.jpg) ### Ann Arbor Regent Hotel & Suites 10/10 Excellent "Clean room" [](https://expedia.ca/Ann-Arbor-Hotels-Ann-Arbor-Regent-Hotel-Suites.h18996.Hotel-Information) ![Comfort Inn & Suites University South](//images.trvl-media.com/lodging/1000000/920000/915500/915500/5c96e5f1_y.jpg) ### Comfort Inn & Suites University South 10/10 Excellent "Very clean and nice size room we enjoyed the pool and breakfast was great definitely a safe nice place.." 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